PubRank

Randy J Seeley

Author PubWeight™ 203.61‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Hypothalamic mTOR signaling regulates food intake. Science 2006 8.62
2 High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. Hepatology 2010 4.11
3 A randomized trial comparing a very low carbohydrate diet and a calorie-restricted low fat diet on body weight and cardiovascular risk factors in healthy women. J Clin Endocrinol Metab 2003 3.93
4 Mice lacking ghrelin receptors resist the development of diet-induced obesity. J Clin Invest 2005 3.92
5 Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding. Cell Metab 2009 3.07
6 Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia. Diabetes 2003 2.90
7 A controlled high-fat diet induces an obese syndrome in rats. J Nutr 2003 2.80
8 Obesity and leptin resistance: distinguishing cause from effect. Trends Endocrinol Metab 2010 2.79
9 Cloned mice have an obese phenotype not transmitted to their offspring. Nat Med 2002 2.68
10 Weight-independent changes in blood glucose homeostasis after gastric bypass or vertical sleeve gastrectomy in rats. Gastroenterology 2011 2.45
11 Effects of a fixed meal pattern on ghrelin secretion: evidence for a learned response independent of nutrient status. Endocrinology 2005 2.43
12 A surgical model in male obese rats uncovers protective effects of bile acids post-bariatric surgery. Endocrinology 2013 2.39
13 Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats. Endocrinology 2007 2.37
14 A role for central nervous system PPAR-γ in the regulation of energy balance. Nat Med 2011 2.34
15 Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake. Diabetes 2008 2.33
16 The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness. J Neurosci 2002 2.26
17 Weight loss through ileal transposition is accompanied by increased ileal hormone secretion and synthesis in rats. Am J Physiol Endocrinol Metab 2004 2.21
18 Is the energy homeostasis system inherently biased toward weight gain? Diabetes 2003 2.14
19 Comparative analysis of ACTH and corticosterone sampling methods in rats. Am J Physiol Endocrinol Metab 2005 2.02
20 The catabolic action of insulin in the brain is mediated by melanocortins. J Neurosci 2002 1.95
21 Sleeve gastrectomy induces loss of weight and fat mass in obese rats, but does not affect leptin sensitivity. Gastroenterology 2010 1.80
22 All bariatric surgeries are not created equal: insights from mechanistic comparisons. Endocr Rev 2012 1.74
23 The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity. J Neurosci 2008 1.71
24 The integrative role of CNS fuel-sensing mechanisms in energy balance and glucose regulation. Annu Rev Physiol 2008 1.67
25 Vertical sleeve gastrectomy is effective in two genetic mouse models of glucagon-like Peptide 1 receptor deficiency. Diabetes 2013 1.64
26 Sleeve gastrectomy in rats improves postprandial lipid clearance by reducing intestinal triglyceride secretion. Gastroenterology 2011 1.64
27 GLP-1 and energy balance: an integrated model of short-term and long-term control. Nat Rev Endocrinol 2011 1.62
28 Insulin and leptin as adiposity signals. Recent Prog Horm Res 2004 1.60
29 CNS glucagon-like peptide-1 receptors mediate endocrine and anxiety responses to interoceptive and psychogenic stressors. J Neurosci 2003 1.60
30 Cooperation between brain and islet in glucose homeostasis and diabetes. Nature 2013 1.59
31 GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats. Diabetes 2013 1.58
32 Duodenal-jejunal exclusion improves glucose tolerance in the diabetic, Goto-Kakizaki rat by a GLP-1 receptor-mediated mechanism. J Gastrointest Surg 2009 1.54
33 Improved rodent maternal metabolism but reduced intrauterine growth after vertical sleeve gastrectomy. Sci Transl Med 2013 1.54
34 Impaired glucose tolerance in rats fed low-carbohydrate, high-fat diets. Am J Physiol Endocrinol Metab 2013 1.54
35 Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. Am J Physiol Gastrointest Liver Physiol 2010 1.54
36 Hyperphagia and increased fat accumulation in two models of chronic CNS glucagon-like peptide-1 loss of function. J Neurosci 2011 1.54
37 Targeted estrogen delivery reverses the metabolic syndrome. Nat Med 2012 1.51
38 Sexual differences in the control of energy homeostasis. Front Neuroendocrinol 2009 1.50
39 Insulin and the blood-brain barrier. Curr Pharm Des 2003 1.49
40 Targeting the CNS to treat type 2 diabetes. Nat Rev Drug Discov 2009 1.45
41 Consumption of a high-fat diet alters the homeostatic regulation of energy balance. Physiol Behav 2004 1.43
42 Perinatal exposure to bisphenol-a and the development of metabolic syndrome in CD-1 mice. Endocrinology 2010 1.38
43 Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect. J Clin Invest 2014 1.33
44 Pleasurable behaviors reduce stress via brain reward pathways. Proc Natl Acad Sci U S A 2010 1.33
45 Physiology: obesity and gut flora. Nature 2006 1.32
46 The effects of vertical sleeve gastrectomy in rodents are ghrelin independent. Gastroenterology 2012 1.28
47 The role of GM-CSF in adipose tissue inflammation. Am J Physiol Endocrinol Metab 2008 1.26
48 Roux en Y gastric bypass increases ethanol intake in the rat. Obes Surg 2013 1.25
49 Mechanisms of oleoylethanolamide-induced changes in feeding behavior and motor activity. Am J Physiol Regul Integr Comp Physiol 2005 1.23
50 Central nervous system mechanisms linking the consumption of palatable high-fat diets to the defense of greater adiposity. Cell Metab 2012 1.23
51 GM-CSF action in the CNS decreases food intake and body weight. J Clin Invest 2005 1.23
52 Role of central nervous system glucagon-like Peptide-1 receptors in enteric glucose sensing. Diabetes 2008 1.22
53 Regulation of food intake through hypothalamic signaling networks involving mTOR. Annu Rev Nutr 2008 1.22
54 Eating elicited by orexin-a, but not melanin-concentrating hormone, is opioid mediated. Endocrinology 2002 1.22
55 Fibroblast growth factor 21 mediates specific glucagon actions. Diabetes 2013 1.20
56 Sexually different actions of leptin in proopiomelanocortin neurons to regulate glucose homeostasis. Am J Physiol Endocrinol Metab 2008 1.20
57 The role of CNS fuel sensing in energy and glucose regulation. Gastroenterology 2007 1.19
58 Complex regulation of mammalian target of rapamycin complex 1 in the basomedial hypothalamus by leptin and nutritional status. Endocrinology 2009 1.19
59 Effect of growth hormone on susceptibility to diet-induced obesity. Endocrinology 2006 1.18
60 Insulin and leptin combine additively to reduce food intake and body weight in rats. Endocrinology 2002 1.18
61 Similar effects of roux-en-Y gastric bypass and vertical sleeve gastrectomy on glucose regulation in rats. Physiol Behav 2011 1.15
62 Fibroblast growth factor-19 action in the brain reduces food intake and body weight and improves glucose tolerance in male rats. Endocrinology 2012 1.15
63 Hormones and diet, but not body weight, control hypothalamic microglial activity. Glia 2013 1.15
64 Vertical sleeve gastrectomy reduces hepatic steatosis while increasing serum bile acids in a weight-loss-independent manner. Obesity (Silver Spring) 2013 1.13
65 Expression of new loci associated with obesity in diet-induced obese rats: from genetics to physiology. Obesity (Silver Spring) 2011 1.12
66 Mice lacking the syndecan-3 gene are resistant to diet-induced obesity. J Clin Invest 2004 1.11
67 Diet-induced weight loss is associated with decreases in plasma serum amyloid a and C-reactive protein independent of dietary macronutrient composition in obese subjects. J Clin Endocrinol Metab 2005 1.11
68 Leptin in energy balance and reward: two faces of the same coin? Neuron 2006 1.11
69 Wired on sugar: the role of the CNS in the regulation of glucose homeostasis. Nat Rev Neurosci 2012 1.10
70 Differences in the central anorectic effects of glucagon-like peptide-1 and exendin-4 in rats. Diabetes 2009 1.10
71 The role of central glucagon-like peptide-1 in mediating the effects of visceral illness: differential effects in rats and mice. Endocrinology 2004 1.09
72 Meal-anticipatory glucagon-like peptide-1 secretion in rats. Endocrinology 2009 1.08
73 The role of energy expenditure in the differential weight loss in obese women on low-fat and low-carbohydrate diets. J Clin Endocrinol Metab 2004 1.08
74 The effect of fat removal on glucose tolerance is depot specific in male and female mice. Am J Physiol Endocrinol Metab 2007 1.08
75 Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity. PLoS One 2008 1.07
76 Consumption of a high-fat diet induces central insulin resistance independent of adiposity. Physiol Behav 2011 1.07
77 Comparison of central and peripheral administration of C75 on food intake, body weight, and conditioned taste aversion. Diabetes 2002 1.07
78 Roux-en-Y gastric bypass surgery but not vertical sleeve gastrectomy decreases bone mass in male rats. Endocrinology 2013 1.05
79 Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism. Obesity (Silver Spring) 2009 1.04
80 New ways in which GLP-1 can regulate glucose homeostasis. J Clin Invest 2005 1.04
81 Gastric bypass surgery attenuates ethanol consumption in ethanol-preferring rats. Biol Psychiatry 2012 1.04
82 Diet-induced obese mice are leptin insufficient after weight reduction. Obesity (Silver Spring) 2009 1.04
83 Effect of vertical sleeve gastrectomy on food selection and satiation in rats. Am J Physiol Endocrinol Metab 2012 1.04
84 Sexually dimorphic responses to fat loss after caloric restriction or surgical lipectomy. Am J Physiol Endocrinol Metab 2007 1.03
85 Synaptic plasticity in neuronal circuits regulating energy balance. Nat Neurosci 2012 1.03
86 Expression of biologically active rat apolipoprotein AIV in Escherichia coli. Physiol Behav 2003 1.02
87 Bypassing the duodenum does not improve insulin resistance associated with diet-induced obesity in rodents. Obesity (Silver Spring) 2010 1.02
88 Peptide designed to elicit apoptosis in adipose tissue endothelium reduces food intake and body weight. Diabetes 2010 1.00
89 High-fat-diet-induced obesity causes an inflammatory and tumor-promoting microenvironment in the rat kidney. Dis Model Mech 2012 1.00
90 Syndecan-3 modulates food intake by interacting with the melanocortin/AgRP pathway. Ann N Y Acad Sci 2003 0.99
91 Central angiotensin II has catabolic action at white and brown adipose tissue. Am J Physiol Endocrinol Metab 2011 0.98
92 Angiotensin type 1a receptors in the paraventricular nucleus of the hypothalamus protect against diet-induced obesity. J Neurosci 2013 0.97
93 The effect of angiotensin-converting enzyme inhibition using captopril on energy balance and glucose homeostasis. Endocrinology 2009 0.95
94 Effect of vertical sleeve gastrectomy in melanocortin receptor 4-deficient rats. Am J Physiol Endocrinol Metab 2012 0.95
95 Increased dietary fat attenuates the anorexic effects of intracerebroventricular injections of MTII. Endocrinology 2003 0.95
96 Ciliary neurotrophic factor and leptin induce distinct patterns of immediate early gene expression in the brain. Diabetes 2004 0.93
97 The role of previous exposure in the appetitive and consummatory effects of orexigenic neuropeptides. Peptides 2005 0.93
98 Role of central glucagon-like peptide-1 in hypothalamo-pituitary-adrenocortical facilitation following chronic stress. Exp Neurol 2007 0.92
99 Fatty acid synthase inhibitors modulate energy balance via mammalian target of rapamycin complex 1 signaling in the central nervous system. Diabetes 2008 0.92
100 Regulation of gastric emptying rate and its role in nutrient-induced GLP-1 secretion in rats after vertical sleeve gastrectomy. Am J Physiol Endocrinol Metab 2013 0.92
101 Intraventricular melanin-concentrating hormone stimulates water intake independent of food intake. Am J Physiol Regul Integr Comp Physiol 2003 0.90
102 Mice with chronically increased circulating ghrelin develop age-related glucose intolerance. Am J Physiol Endocrinol Metab 2008 0.90
103 C75 inhibits food intake by increasing CNS glucose metabolism. Nat Med 2003 0.89
104 Visceral abdominal fat is correlated with whole-body fat and physical activity among 8-y-old children at risk of obesity. Am J Clin Nutr 2007 0.89
105 Transplantation or removal of intra-abdominal adipose tissue prevents age-induced glucose insensitivity. Physiol Behav 2010 0.89
106 Adrenalectomy alters the sensitivity of the central nervous system melanocortin system. Diabetes 2003 0.89
107 The roles of leptin receptors on POMC neurons in the regulation of sex-specific energy homeostasis. Physiol Behav 2010 0.88
108 Report of the American Gastroenterological Association (AGA) Institute Obesity Task Force. Gastroenterology 2007 0.88
109 Obesity induced by a high-fat diet downregulates apolipoprotein A-IV gene expression in rat hypothalamus. Am J Physiol Endocrinol Metab 2004 0.88
110 Reversal of diet-induced obesity increases insulin transport into cerebrospinal fluid and restores sensitivity to the anorexic action of central insulin in male rats. Endocrinology 2013 0.88
111 Mechanisms underlying weight loss and metabolic improvements in rodent models of bariatric surgery. Diabetologia 2014 0.87
112 Apolipoprotein A-IV interacts synergistically with melanocortins to reduce food intake. Am J Physiol Regul Integr Comp Physiol 2005 0.87
113 Integration of satiety signals by the central nervous system. Curr Biol 2013 0.87
114 Rapid and weight-independent improvement of glucose tolerance induced by a peptide designed to elicit apoptosis in adipose tissue endothelium. Diabetes 2012 0.87
115 High-fat diet changes the temporal profile of GLP-1 receptor-mediated hypophagia in rats. Am J Physiol Regul Integr Comp Physiol 2013 0.86
116 High fat diet alters lactation outcomes: possible involvement of inflammatory and serotonergic pathways. PLoS One 2012 0.86
117 The anorectic effect of GLP-1 in rats is nutrient dependent. PLoS One 2012 0.85
118 Physiology. Food as a hormone. Science 2013 0.85
119 Suppression of food intake by glucagon-like peptide-1 receptor agonists: relative potencies and role of dipeptidyl peptidase-4. Endocrinology 2012 0.85
120 Learned meal initiation attenuates the anorexic effects of the melanocortin agonist MTII. Diabetes 2003 0.84
121 High-fat diet induced adiposity in mice with targeted disruption of the dopamine-3 receptor gene. Behav Brain Res 2004 0.84
122 Oral L-arginine stimulates GLP-1 secretion to improve glucose tolerance in male mice. Endocrinology 2013 0.83
123 Neuropeptide Y and lipid increase apolipoprotein AIV gene expression in rat hypothalamus. Brain Res 2003 0.82
124 Clinical endocrinology and metabolism. Regulation of energy homeostasis by peripheral signals. Best Pract Res Clin Endocrinol Metab 2004 0.82
125 Ethanol consumption in mice with a targeted disruption of the dopamine-3 receptor gene. Addict Biol 2003 0.82
126 Two novel paradigms for the simultaneous assessment of conditioned taste aversion and food intake effects of anorexic agents. Physiol Behav 2003 0.81
127 Alcohol drinking in MCH receptor-1-deficient mice. Alcohol Clin Exp Res 2007 0.81
128 7-OH-DPAT selectively reduces intake of both chow and high fat diets in different food intake regimens. Pharmacol Biochem Behav 2003 0.81
129 Role for dopamine-3 receptor in the hyperphagia of an unanticipated high-fat meal in rats. Pharmacol Biochem Behav 2006 0.80
130 Physiological responses to acute psychological stress are reduced by the PPARγ agonist rosiglitazone. Endocrinology 2012 0.80
131 Carbohydrate content of post-operative diet influences the effect of vertical sleeve gastrectomy on body weight reduction in obese rats. Obes Surg 2012 0.80
132 Acute 3rd-ventricular amylin infusion potently reduces food intake but does not produce aversive consequences. Peptides 2002 0.80
133 Hyperphagia: current concepts and future directions proceedings of the 2nd international conference on hyperphagia. Obesity (Silver Spring) 2014 0.80
134 Removal of intra-abdominal visceral adipose tissue improves glucose tolerance in rats: role of hepatic triglyceride storage. Physiol Behav 2011 0.80
135 Differential effects of adrenalectomy on melanin-concentrating hormone and orexin A. Endocrinology 2004 0.80
136 Hap1 and GABA: thinking about food intake. Cell Metab 2006 0.79
137 Fat hormones pull their weight in the CNS. Nat Med 2004 0.79
138 The effects of GLP-1 infusion in the hepatic portal region on food intake. Regul Pept 2009 0.79
139 Medicine. The microbes made me eat it. Science 2010 0.79
140 Neuropeptide Y prepares rats for scheduled feeding. Am J Physiol Regul Integr Comp Physiol 2005 0.79
141 The role of small heterodimer partner in nonalcoholic fatty liver disease improvement after sleeve gastrectomy in mice. Obesity (Silver Spring) 2014 0.78
142 The effects of the melanocortin agonist (MT-II) on subcutaneous and visceral adipose tissue in rodents. J Pharmacol Exp Ther 2007 0.78
143 Hypothalamic Akt/PKB signaling in regulation of food intake. Front Biosci (Schol Ed) 2012 0.78
144 Diabetes: the search for mechanisms underlying bariatric surgery. Nat Rev Endocrinol 2013 0.78
145 Chronic food restriction and reduced dietary fat: risk factors for bouts of overeating. Physiol Behav 2005 0.78
146 Bile Acid Signaling: Mechanism for Bariatric Surgery, Cure for NASH? Dig Dis 2015 0.78
147 Metabolic, behavioral, and reproductive effects of vertical sleeve gastrectomy in an obese rat model of polycystic ovary syndrome. Obes Surg 2014 0.78
148 The role of the transcription factor ETV5 in insulin exocytosis. Diabetologia 2013 0.78
149 The effect of vertical sleeve gastrectomy on a rat model of polycystic ovarian syndrome. Endocrinology 2011 0.78
150 Altered feeding responses in mice with targeted disruption of the dopamine-3 receptor gene. Behav Neurosci 2003 0.77
151 Angiotensin-converting enzyme inhibition reduces food intake and weight gain and improves glucose tolerance in melanocortin-4 receptor deficient female rats. Physiol Behav 2013 0.77
152 GLP-1R agonism enhances adjustable gastric banding in diet-induced obese rats. Diabetes 2013 0.77
153 More neurons, less weight. Nat Med 2005 0.77
154 Weight loss by calorie restriction versus bariatric surgery differentially regulates the hypothalamo-pituitary-adrenocortical axis in male rats. Stress 2014 0.77
155 How diabetes went to our heads. Nat Med 2006 0.77
156 Efficacy of increasing physical activity to reduce children's visceral fat: a pilot randomized controlled trial. Int J Pediatr Obes 2010 0.76
157 The melanocortin-4 receptor integrates circadian light cues and metabolism. Endocrinology 2015 0.76
158 The regulation of energy balance by the central nervous system. Psychiatr Clin North Am 2005 0.76
159 Voluntary consumption of ethyl oleate reduces food intake and body weight in rats. Physiol Behav 2007 0.75
160 Our evolving understanding of the interaction between leptin and dopamine system to regulate ingestive behaviors. Mol Metab 2012 0.75