John Koomen

Author PubWeight™ 34.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Feature extraction and quantification for mass spectrometry in biomedical applications using the mean spectrum. Bioinformatics 2005 4.26
2 HDAC6 modulates cell motility by altering the acetylation level of cortactin. Mol Cell 2007 3.99
3 A chemical and phosphoproteomic characterization of dasatinib action in lung cancer. Nat Chem Biol 2010 2.53
4 Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities. Oncogene 2005 1.43
5 Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation. PLoS One 2010 1.41
6 Lipid/peptide/nucleotide separation with MALDI-ion mobility-TOF MS. Anal Chem 2004 1.38
7 SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities. Mol Cell Biol 2011 1.35
8 Involvement of the conserved adaptor protein Alix in actin cytoskeleton assembly. J Biol Chem 2006 1.30
9 Charting the landscape of tandem BRCT domain-mediated protein interactions. Sci Signal 2012 1.19
10 Phosphoproteomics identifies driver tyrosine kinases in sarcoma cell lines and tumors. Cancer Res 2012 1.16
11 SIRT1 negatively regulates the activities, functions, and protein levels of hMOF and TIP60. Mol Cell Biol 2012 1.15
12 Pharmacoproteomic analysis of prechemotherapy and postchemotherapy plasma samples from patients receiving neoadjuvant or adjuvant chemotherapy for breast carcinoma. Cancer 2004 1.12
13 Mass spectrometry mapping of epidermal growth factor receptor phosphorylation related to oncogenic mutations and tyrosine kinase inhibitor sensitivity. J Proteome Res 2010 1.10
14 Urine collection and processing for protein biomarker discovery and quantification. Cancer Epidemiol Biomarkers Prev 2010 1.08
15 Stemness of B-cell progenitors in multiple myeloma bone marrow. Clin Cancer Res 2012 1.06
16 MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output. EMBO J 2010 1.03
17 Characterizing tyrosine phosphorylation signaling in lung cancer using SH2 profiling. PLoS One 2010 0.98
18 Extracellular signal-regulated kinase (ERK) phosphorylates histone deacetylase 6 (HDAC6) at serine 1035 to stimulate cell migration. J Biol Chem 2013 0.95
19 Serum amyloid A as a tumor marker in sera of nude mice with orthotopic human pancreatic cancer and in plasma of patients with pancreatic cancer. Int J Oncol 2005 0.94
20 Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms. Mol Syst Biol 2013 0.93
21 Regulation of SirT1-nucleomethylin binding by rRNA coordinates ribosome biogenesis with nutrient availability. Mol Cell Biol 2013 0.89
22 A circulating ligand for galectin-3 is a haptoglobin-related glycoprotein elevated in individuals with colon cancer. Gastroenterology 2004 0.87
23 hMOF acetylation of DBC1/CCAR2 prevents binding and inhibition of SirT1. Mol Cell Biol 2013 0.86
24 The NAD+ synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) regulates ribosomal RNA transcription. J Biol Chem 2013 0.81
25 IPEP: an in silico tool to examine proteolytic peptides for mass spectrometry. Bioinformatics 2008 0.80
26 Oxadiazole-isopropylamides as potent and noncovalent proteasome inhibitors. J Med Chem 2013 0.77