PubRank

Matti Poutanen

Author PubWeight™ 87.76‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Male pheromone-stimulated neurogenesis in the adult female brain: possible role in mating behavior. Nat Neurosci 2007 2.55
2 The transcriptional corepressor RIP140 regulates oxidative metabolism in skeletal muscle. Cell Metab 2007 1.54
3 Human HSD17B1 expression masculinizes transgenic female mice. Mol Cell Endocrinol 2008 1.46
4 The androgen and progesterone receptors regulate distinct gene networks and cellular functions in decidualizing endometrium. Endocrinology 2008 1.42
5 Angiogenic activity of human chorionic gonadotropin through LH receptor activation on endothelial and epithelial cells of the endometrium. FASEB J 2006 1.29
6 The diversity of sex steroid action: novel functions of hydroxysteroid (17β) dehydrogenases as revealed by genetically modified mouse models. J Endocrinol 2011 1.13
7 Molecular characterization of postnatal development of testicular steroidogenesis in luteinizing hormone receptor knockout mice. Endocrinology 2003 1.12
8 Discovery in silico and characterization in vitro of novel genes exclusively expressed in the mouse epididymis. Mol Endocrinol 2003 1.10
9 Reproductive disturbances, pituitary lactotrope adenomas, and mammary gland tumors in transgenic female mice producing high levels of human chorionic gonadotropin. Endocrinology 2002 1.09
10 Targeted inactivation of the androgen receptor gene in murine proximal epididymis causes epithelial hypotrophy and obstructive azoospermia. Endocrinology 2010 1.09
11 Elevated steroidogenesis, defective reproductive organs, and infertility in transgenic male mice overexpressing human chorionic gonadotropin. Endocrinology 2003 1.05
12 A fluorescent Tie1 reporter allows monitoring of vascular development and endothelial cell isolation from transgenic mouse embryos. FASEB J 2002 1.02
13 The low gonadotropin-independent constitutive production of testicular testosterone is sufficient to maintain spermatogenesis. Proc Natl Acad Sci U S A 2003 1.01
14 Increased exposure to estrogens disturbs maturation, steroidogenesis, and cholesterol homeostasis via estrogen receptor alpha in adult mouse Leydig cells. Endocrinology 2009 1.01
15 Testosterone replacement therapy induces spermatogenesis and partially restores fertility in luteinizing hormone receptor knockout mice. Endocrinology 2004 1.00
16 Dicer1 ablation in the mouse epididymis causes dedifferentiation of the epithelium and imbalance in sex steroid signaling. PLoS One 2012 0.99
17 Inactivation of estrogen receptor α in bone-forming cells induces bone loss in female mice. FASEB J 2012 0.98
18 Mouse models of infertility due to swollen spermatozoa. Mol Cell Endocrinol 2004 0.98
19 Epididymal dysfunction initiated by the expression of simian virus 40 T-antigen leads to angulated sperm flagella and infertility in transgenic mice. Mol Endocrinol 2002 0.98
20 Sperm volume regulation: maturational changes in fertile and infertile transgenic mice and association with kinematics and tail angulation. Biol Reprod 2002 0.97
21 Knockout of luteinizing hormone receptor abolishes the effects of follicle-stimulating hormone on preovulatory maturation and ovulation of mouse graafian follicles. Mol Endocrinol 2005 0.96
22 Endometrial and endometriotic concentrations of estrone and estradiol are determined by local metabolism rather than circulating levels. J Clin Endocrinol Metab 2012 0.95
23 Female mice carrying a ubiquitin promoter-Insl3 transgene have descended ovaries and inguinal hernias but normal fertility. Mol Cell Endocrinol 2003 0.94
24 Bmx tyrosine kinase transgene induces skin hyperplasia, inflammatory angiogenesis, and accelerated wound healing. Mol Biol Cell 2004 0.94
25 Stromal activation associated with development of prostate cancer in prostate-targeted fibroblast growth factor 8b transgenic mice. Neoplasia 2010 0.94
26 Elevated aromatase expression in osteoblasts leads to increased bone mass without systemic adverse effects. J Bone Miner Res 2009 0.93
27 Human chorionic gonadotropin (hCG) up-regulates wnt5b and wnt7b in the mammary gland, and hCGbeta transgenic female mice present with mammary Gland tumors exhibiting characteristics of the Wnt/beta-catenin pathway activation. Endocrinology 2007 0.92
28 Improved statistical modeling of tumor growth and treatment effect in preclinical animal studies with highly heterogeneous responses in vivo. Clin Cancer Res 2012 0.92
29 Human hydroxysteroid (17-beta) dehydrogenase 1 expression enhances estrogen sensitivity of MCF-7 breast cancer cell xenografts. Endocrinology 2006 0.91
30 Mouse cysteine-rich secretory protein 4 (CRISP4): a member of the Crisp family exclusively expressed in the epididymis in an androgen-dependent manner. Biol Reprod 2005 0.91
31 Multiple sites of tumorigenesis in transgenic mice overproducing hCG. Mol Cell Endocrinol 2005 0.91
32 Infravesical obstruction in aromatase over expressing transgenic male mice with increased ratio of serum estrogen-to-androgen concentration. J Urol 2002 0.91
33 Estrogen biosynthesis and signaling in endometriosis. Mol Cell Endocrinol 2011 0.90
34 Transgenic mice expressing p450 aromatase as a model for male infertility associated with chronic inflammation in the testis. Endocrinology 2005 0.90
35 Epididymal protein Rnase10 is required for post-testicular sperm maturation and male fertility. FASEB J 2012 0.90
36 Mammary gland development in transgenic male mice expressing human P450 aromatase. Endocrinology 2002 0.89
37 Increased endogenous estrogen synthesis leads to the sequential induction of prostatic inflammation (prostatitis) and prostatic pre-malignancy. Am J Pathol 2009 0.88
38 Interactions between inflammatory signals and the progesterone receptor in regulating gene expression in pregnant human uterine myocytes. J Cell Mol Med 2012 0.88
39 ERβ1 represses FOXM1 expression through targeting ERα to control cell proliferation in breast cancer. Am J Pathol 2011 0.88
40 Human testicular peritubular cells host putative stem Leydig cells with steroidogenic capacity. J Clin Endocrinol Metab 2014 0.88
41 Genetically modified mouse models in studies of luteinising hormone action. Mol Cell Endocrinol 2006 0.88
42 Fast and sensitive liquid chromatography-mass spectrometry assay for seven androgenic and progestagenic steroids in human serum. J Steroid Biochem Mol Biol 2011 0.88
43 Elevated expression of the metabolic regulator receptor-interacting protein 140 results in cardiac hypertrophy and impaired cardiac function. Cardiovasc Res 2010 0.88
44 Discovery and characterization of new epididymis-specific beta-defensins in mice. Biochim Biophys Acta 2005 0.88
45 Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice. Hum Mol Genet 2010 0.87
46 Fetal but not adult Leydig cells are susceptible to adenoma formation in response to persistently high hCG level: a study on hCG overexpressing transgenic mice. Oncogene 2005 0.87
47 Bfk, a novel member of the bcl2 gene family, is highly expressed in principal cells of the mouse epididymis and demonstrates a predominant nuclear localization. Endocrinology 2007 0.87
48 Murine relaxin-like factor promoter: functional characterization and regulation by transcription factors steroidogenic factor 1 and DAX-1. Endocrinology 2002 0.87
49 Hydroxysteroid (17beta) dehydrogenase 7 activity is essential for fetal de novo cholesterol synthesis and for neuroectodermal survival and cardiovascular differentiation in early mouse embryos. Endocrinology 2010 0.86
50 FELASA guidelines for the refinement of methods for genotyping genetically-modified rodents: a report of the Federation of European Laboratory Animal Science Associations Working Group. Lab Anim 2013 0.86
51 Female mice expressing constitutively active mutants of FSH receptor present with a phenotype of premature follicle depletion and estrogen excess. Endocrinology 2010 0.86
52 Placenta defects and embryonic lethality resulting from disruption of mouse hydroxysteroid (17-beta) dehydrogenase 2 gene. Mol Endocrinol 2007 0.85
53 Phenotype characteristics of transgenic male mice expressing human aromatase under ubiquitin C promoter. J Steroid Biochem Mol Biol 2003 0.85
54 Hydroxysteroid (17{beta}) dehydrogenase 12 is essential for mouse organogenesis and embryonic survival. Endocrinology 2010 0.84
55 Phenotypic characterisation of mice with exaggerated and missing LH/hCG action. Mol Cell Endocrinol 2006 0.84
56 Multiple structural and functional abnormalities in the p450 aromatase expressing transgenic male mice are ameliorated by a p450 aromatase inhibitor. Am J Pathol 2004 0.84
57 Fertility in luteinizing hormone receptor-knockout mice after wild-type ovary transplantation demonstrates redundancy of extragonadal luteinizing hormone action. J Clin Invest 2005 0.83
58 Differential endocrine regulation of genes enriched in initial segment and distal caput of the mouse epididymis as revealed by genome-wide expression profiling. Biol Reprod 2006 0.83
59 The transcriptional co-factor RIP140 regulates mammary gland development by promoting the generation of key mitogenic signals. Development 2013 0.83
60 A single dose of enterolactone activates estrogen signaling and regulates expression of circadian clock genes in mice. J Nutr 2011 0.82
61 Loss of cysteine-rich secretory protein 4 (Crisp4) leads to deficiency in sperm-zona pellucida interaction in mice. Biol Reprod 2012 0.82
62 Down-regulation of the histone methyltransferase EZH2 contributes to the epigenetic programming of decidualizing human endometrial stromal cells. Mol Endocrinol 2011 0.82
63 Novel epididymal protease inhibitors with Kazal or WAP family domain. Biochem Biophys Res Commun 2006 0.82
64 Epithelial cells are the major site of hydroxysteroid (17beta) dehydrogenase 2 and androgen receptor expression in fetal mouse lungs during the period overlapping the surge of surfactant. J Steroid Biochem Mol Biol 2009 0.82
65 High levels of luteinizing hormone analog stimulate gonadal and adrenal tumorigenesis in mice transgenic for the mouse inhibin-alpha-subunit promoter/Simian virus 40 T-antigen fusion gene. Oncogene 2003 0.82
66 Extragonadal LH/hCG action--not yet time to rewrite textbooks. Mol Cell Endocrinol 2007 0.82
67 Immortalization of epididymal epithelium in transgenic mice expressing simian virus 40 T antigen: characterization of cell lines and regulation of the polyoma enhancer activator 3. Endocrinology 2003 0.81
68 [Pathogenesis of endometriosis]. Duodecim 2011 0.81
69 Intra-tissue steroid profiling indicates differential progesterone and testosterone metabolism in the endometrium and endometriosis lesions. J Clin Endocrinol Metab 2014 0.81
70 Resampling reveals sample-level differential expression in clinical genome-wide studies. OMICS 2009 0.81
71 Developmental, estrogen induced infravesical obstruction is reversible in adult male rodents. J Urol 2002 0.80
72 Adenosine triphosphate induces Ca2+ signal in epithelial cells of the mouse caput epididymis through activation of P2X and P2Y purinergic receptors. Biol Reprod 2002 0.80
73 Fibroblast growth factor 8b causes progressive stromal and epithelial changes in the epididymis and degeneration of the seminiferous epithelium in the testis of transgenic mice. Biol Reprod 2012 0.80
74 Transgenic and knockout mouse models for the study of luteinizing hormone and luteinizing hormone receptor function. Mol Cell Endocrinol 2002 0.80
75 Overexpression of Bcl-W in the testis disrupts spermatogenesis: revelation of a role of BCL-W in male germ cell cycle control. Mol Endocrinol 2003 0.80
76 Novel hydroxysteroid (17beta) dehydrogenase 1 inhibitors reverse estrogen-induced endometrial hyperplasia in transgenic mice. Am J Pathol 2010 0.79
77 Obesity in transgenic female mice with constitutively elevated luteinizing hormone secretion. Am J Physiol Endocrinol Metab 2003 0.78
78 Understanding the diversity of sex steroid action. J Endocrinol 2012 0.78
79 Regional expression of androgen receptor coregulators and androgen action in the mouse epididymis. J Androl 2011 0.78
80 Endogenously elevated androgens alter the developmental programming of the hypothalamic-pituitary axis in male mice. Mol Cell Endocrinol 2010 0.78
81 Identification of novel epididymal genes by expression profiling and in silico gene discovery. Mol Cell Endocrinol 2006 0.78
82 LC-MS analysis of estradiol in human serum and endometrial tissue: Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization. J Mass Spectrom 2013 0.78
83 Sex steroid-dependent and -independent action of hydroxysteroid (17beta) Dehydrogenase 2: evidence from transgenic female mice. Endocrinology 2009 0.78
84 In vivo mouse model for analysis of hydroxysteroid (17beta) dehydrogenase 1 inhibitors. Mol Cell Endocrinol 2008 0.77
85 Loss of Bmyc results in increased apoptosis associated with upregulation of Myc expression in juvenile murine testis. Reproduction 2012 0.77
86 Indirect Sertoli cell-mediated ablation of germ cells in mice expressing the inhibin-alpha promoter/herpes simplex virus thymidine kinase transgene. Biol Reprod 2004 0.77
87 Inhibition of oocyte growth factors in vivo modulates ovarian folliculogenesis in neonatal and immature mice. Reproduction 2009 0.77
88 Members of the murine Pate family are predominantly expressed in the epididymis in a segment-specific fashion and regulated by androgens and other testicular factors. Reprod Biol Endocrinol 2011 0.77
89 ErbB4, a receptor tyrosine kinase, coordinates organization of the seminiferous tubules in the developing testis. Mol Endocrinol 2014 0.76
90 Transgenic mice harboring murine luteinizing hormone receptor promoter/beta-galactosidase fusion genes: different structural and hormonal requirements of expression in the testis, ovary, and adrenal gland. Endocrinology 2002 0.76
91 Ovarian endometriosis signatures established through discovery and directed mass spectrometry analysis. J Proteome Res 2014 0.76
92 Immortalization by large T-antigen of the adult epididymal duct epithelium. Mol Cell Endocrinol 2004 0.76
93 Activation of androgens by hydroxysteroid (17beta) dehydrogenase 1 in vivo as a cause of prenatal masculinization and ovarian benign serous cystadenomas. Mol Endocrinol 2007 0.76
94 Delay of postnatal maturation sensitizes the mouse prostate to testosterone-induced pronounced hyperplasia: protective role of estrogen receptor-beta. Am J Pathol 2007 0.76
95 Skeletal changes in transgenic male mice expressing human cytochrome p450 aromatase. J Bone Miner Res 2004 0.76
96 Overexpression of human hydroxysteroid (17beta) dehydrogenase 2 induces disturbance in skeletal development in young male mice. J Bone Miner Res 2008 0.76
97 Short-term pharmacological suppression of the hyperprolactinemia of infertile hCG-overproducing female mice persistently restores their fertility. Endocrinology 2012 0.76
98 Transgenic male mice expressing human hydroxysteroid dehydrogenase 2 indicate a role for the enzyme independent of its action on sex steroids. Endocrinology 2007 0.75
99 Transgenic and knockout mouse models for aberrant pituitary-testicular function: relevance to the pathogenesis of cryptorchidism. Turk J Pediatr 2004 0.75
100 Seminal vesicles and urinary bladder as sites of aromatization of androgens in men, evidenced by a CYP19A1-driven luciferase reporter mouse and human tissue specimens. FASEB J 2012 0.75
101 Epididymis-specific promoter-driven gene targeting: a new approach to control epididymal function? Mol Cell Endocrinol 2004 0.75
102 Comparison of liquid chromatography-microchip/mass spectrometry to conventional liquid chromatography-mass spectrometry for the analysis of steroids. Anal Chim Acta 2012 0.75