Published in Oncogene on March 03, 2005
GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis. Proc Natl Acad Sci U S A (2006) 2.08
G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and lamination. Proc Natl Acad Sci U S A (2011) 1.53
Expression analysis of all protease genes reveals cathepsin K to be overexpressed in glioblastoma. PLoS One (2014) 1.41
Persistent transactivation by meis1 replaces hox function in myeloid leukemogenesis models: evidence for co-occupancy of meis1-pbx and hox-pbx complexes on promoters of leukemia-associated genes. Mol Cell Biol (2006) 1.36
The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity. J Biol Chem (2011) 1.35
International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. Pharmacol Rev (2015) 1.29
GPR56-regulated granule cell adhesion is essential for rostral cerebellar development. J Neurosci (2009) 1.23
Clearance and prevention of prion infection in cell culture by anti-PrP antibodies. Eur J Neurosci (2006) 1.22
Sharpening the edges of understanding the structure/function of the LPA1 receptor: expression in cancer and mechanisms of regulation. Biochim Biophys Acta (2008) 1.03
Congenital muscular dystrophies: a brief review. Semin Pediatr Neurol (2011) 1.02
Disease-associated GPR56 mutations cause bilateral frontoparietal polymicrogyria via multiple mechanisms. J Biol Chem (2011) 0.97
Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist. Proc Natl Acad Sci U S A (2015) 0.92
GPR56 and the developing cerebral cortex: cells, matrix, and neuronal migration. Mol Neurobiol (2012) 0.88
Splicing variants of the orphan G-protein-coupled receptor GPR56 regulate the activity of transcription factors associated with tumorigenesis. J Cancer Res Clin Oncol (2010) 0.88
SSeCKS/Gravin/AKAP12 attenuates expression of proliferative and angiogenic genes during suppression of v-Src-induced oncogenesis. BMC Cancer (2006) 0.88
Disease-associated mutations prevent GPR56-collagen III interaction. PLoS One (2012) 0.86
GPR56 plays varying roles in endogenous cancer progression. Clin Exp Metastasis (2010) 0.83
A novel GPR56 mutation causes bilateral frontoparietal polymicrogyria. Pediatr Neurol (2011) 0.83
Adhesion G Protein-Coupled Receptors: From In Vitro Pharmacology to In Vivo Mechanisms. Mol Pharmacol (2015) 0.83
Quantitative comparison of a human cancer cell surface proteome between interphase and mitosis. EMBO J (2014) 0.81
Mechanism for adhesion G protein-coupled receptor GPR56-mediated RhoA activation induced by collagen III stimulation. PLoS One (2014) 0.80
Identification of novel tumor-associated cell surface sialoglycoproteins in human glioblastoma tumors using quantitative proteomics. PLoS One (2014) 0.79
Gpr97 is essential for the follicular versus marginal zone B-lymphocyte fate decision. Cell Death Dis (2013) 0.79
Generation and Characterization of UL21-Null Herpes Simplex Virus Type 1. Front Microbiol (2012) 0.78
Dihydromunduletone Is a Small-Molecule Selective Adhesion G Protein-Coupled Receptor Antagonist. Mol Pharmacol (2016) 0.78
High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice. Stem Cell Res (2015) 0.77
G protein-coupled receptors as oncogenic signals in glioma: emerging therapeutic avenues. Neuroscience (2014) 0.76
Adhesion G-protein-coupled receptors: elusive hybrids come of age. Cell Commun Adhes (2013) 0.75
Deletion of Gpr128 results in weight loss and increased intestinal contraction frequency. World J Gastroenterol (2014) 0.75
Expression of G protein-coupled receptor 56 is associated with tumor progression in non-small-cell lung carcinoma patients. Onco Targets Ther (2016) 0.75
Gnaq and Gna11 in the Endothelin Signaling Pathway and Melanoma. Front Genet (2016) 0.75
Gpr110 deficiency decelerates carcinogen-induced hepatocarcinogenesis via activation of the IL-6/STAT3 pathway. Am J Cancer Res (2017) 0.75
Adhesion GPCRs in Tumorigenesis. Handb Exp Pharmacol (2016) 0.75
GPR78 promotes lung cancer cell migration and metastasis by activation of Gαq-Rho GTPase pathway. BMB Rep (2016) 0.75
Identification of differential splicing genes in gliomas using exon expression profiling. Mol Med Rep (2014) 0.75
Potent and highly selective hypoxia-activated achiral phosphoramidate mustards as anticancer drugs. J Med Chem (2008) 2.35
Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma. Nat Med (2003) 2.35
Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302. Mol Cancer Ther (2011) 1.58
Regulation of NMDA receptor trafficking and function by striatal-enriched tyrosine phosphatase (STEP). Eur J Neurosci (2006) 1.52
Mechanisms of neural plasticity following brain injury. Curr Opin Neurobiol (2006) 1.42
Complex interactions between the laminin alpha 4 subunit and integrins regulate endothelial cell behavior in vitro and angiogenesis in vivo. Proc Natl Acad Sci U S A (2002) 1.31
The sigma-1 receptor enhances brain plasticity and functional recovery after experimental stroke. Brain (2011) 1.18
Validation of an LC-MS/MS assay for detecting relevant disaccharides from keratan sulfate as a biomarker for Morquio A syndrome. Bioanalysis (2011) 1.17
Death-associated protein kinase is activated by dephosphorylation in response to cerebral ischemia. J Biol Chem (2005) 1.09
KIBRA: A New Gateway to Learning and Memory? Front Aging Neurosci (2010) 1.09
Targeting of the receptor protein tyrosine phosphatase beta with a monoclonal antibody delays tumor growth in a glioblastoma model. Cancer Res (2006) 1.08
Identification of cathepsin B as a mediator of neuronal death induced by Abeta-activated microglial cells using a functional genomics approach. J Biol Chem (2003) 1.08
Npas4, a novel helix-loop-helix PAS domain protein, is regulated in response to cerebral ischemia. Eur J Neurosci (2006) 1.07
A phase I study of the safety and pharmacokinetics of the hypoxia-activated prodrug TH-302 in combination with doxorubicin in patients with advanced soft tissue sarcoma. Oncology (2011) 1.07
Discoidin domain receptor-1a (DDR1a) promotes glioma cell invasion and adhesion in association with matrix metalloproteinase-2. J Neurooncol (2006) 1.02
A high-throughput turbidometric assay for screening inhibitors of protein disulfide isomerase activity. J Biomol Screen (2004) 0.98
FAS associated phosphatase (FAP-1) blocks apoptosis of astrocytomas through dephosphorylation of FAS. J Neurooncol (2005) 0.95
Expression and function of striatal enriched protein tyrosine phosphatase is profoundly altered in cerebral ischemia. Eur J Neurosci (2008) 0.91
Telomerase-immortalized lymphatic and blood vessel endothelial cells are functionally stable and retain their lineage specificity. Microcirculation (2004) 0.90
Sigma-1 receptor chaperones regulate the secretion of brain-derived neurotrophic factor. Synapse (2012) 0.88
Receptor protein tyrosine phosphatase zeta as a therapeutic target for glioblastoma therapy. Expert Opin Ther Targets (2004) 0.87
Detection of tetrahydrobiopterin by LC-MS/MS in plasma from multiple species. Bioanalysis (2009) 0.84
Biomarker analysis of Morquio syndrome: identification of disease state and drug responsive markers. Orphanet J Rare Dis (2011) 0.83
Aging and survival of cutaneous microvasculature. J Invest Dermatol (2002) 0.83
A pharmacological screening approach for discovery of neuroprotective compounds in ischemic stroke. PLoS One (2013) 0.80
Relative bioavailability of sapropterin from intact and dissolved sapropterin dihydrochloride tablets and the effects of food: a randomized, open-label, crossover study in healthy adults. Clin Ther (2010) 0.78
Functional comparison of long and short splice forms of RPTPbeta: implications for glioblastoma treatment. Neuro Oncol (2005) 0.77
The effects of a sensory motor activities protocol based on the theory of sensory integration on children diagnosed with preprimary impairments. Occup Ther Health Care (2003) 0.75
Linking solubility and permeability assays for maximum throughput and reproducibility. J Biomol Screen (2005) 0.75
A role for antimetabolites in glaucoma tube surgery: current evidence and future directions. Curr Opin Ophthalmol (2016) 0.75