Dirk Eick

Author PubWeight™ 72.23‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7. Science 2007 4.18
2 Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression. Science 2007 3.36
3 Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters. Nat Struct Mol Biol 2011 2.79
4 TFIIH kinase places bivalent marks on the carboxy-terminal domain of RNA polymerase II. Mol Cell 2009 2.61
5 H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex. Mol Cell 2007 2.32
6 CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II. Science 2012 2.05
7 Chemotherapeutic drugs inhibit ribosome biogenesis at various levels. J Biol Chem 2010 2.00
8 Dissection of transcriptional programmes in response to serum and c-Myc in a human B-cell line. Oncogene 2005 1.93
9 Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36. Nat Struct Mol Biol 2011 1.85
10 Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs. Cell Stem Cell 2012 1.80
11 A role for c-Myc in the regulation of ribosomal RNA processing. Nucleic Acids Res 2003 1.80
12 Chemical-genomic dissection of the CTD code. Nat Struct Mol Biol 2010 1.76
13 Dynamic phosphorylation patterns of RNA polymerase II CTD during transcription. Biochim Biophys Acta 2012 1.73
14 Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation. J Cell Biol 2005 1.69
15 CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3'-end processing. EMBO Rep 2009 1.69
16 Molecular evolution of the RNA polymerase II CTD. Trends Genet 2008 1.64
17 Role of the mammalian RNA polymerase II C-terminal domain (CTD) nonconsensus repeats in CTD stability and cell proliferation. Mol Cell Biol 2005 1.55
18 Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation. EMBO J 2012 1.55
19 The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing. EMBO Rep 2008 1.47
20 Latent membrane protein 1 of Epstein-Barr virus coordinately regulates proliferation with control of apoptosis. Oncogene 2005 1.47
21 Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development. EMBO J 2011 1.41
22 Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex. Nucleic Acids Res 2006 1.41
23 Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules. Chem Biol 2006 1.35
24 Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit. Mol Cell Biol 2007 1.31
25 Defects in 18 S or 28 S rRNA processing activate the p53 pathway. J Biol Chem 2010 1.30
26 Ultrashort and progressive 4sU-tagging reveals key characteristics of RNA processing at nucleotide resolution. Genome Res 2012 1.24
27 The last CTD repeat of the mammalian RNA polymerase II large subunit is important for its stability. Nucleic Acids Res 2004 1.23
28 Interferon antagonist NSs of La Crosse virus triggers a DNA damage response-like degradation of transcribing RNA polymerase II. J Biol Chem 2010 1.17
29 In vivo live imaging of RNA polymerase II transcription factories in primary cells. Genes Dev 2013 1.12
30 RNA polymerase II C-terminal heptarepeat domain Ser-7 phosphorylation is established in a mediator-dependent fashion. J Biol Chem 2009 1.12
31 C-myc activation impairs the NF-kappaB and the interferon response: implications for the pathogenesis of Burkitt's lymphoma. Int J Cancer 2007 1.11
32 Estrogen-dependent gene transcription in human breast cancer cells relies upon proteasome-dependent monoubiquitination of histone H2B. Cancer Res 2011 1.08
33 CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo. Nucleic Acids Res 2012 1.05
34 Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription. Nat Cell Biol 2011 1.04
35 Phosphorylation by cyclin-dependent kinase-9 controls ubiquitin-conjugating enzyme-2A function. Cell Cycle 2012 1.01
36 The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing. Nucleic Acids Res 2006 0.97
37 The nuclear organization of Polycomb/Trithorax group response elements in larval tissues of Drosophila melanogaster. Chromosome Res 2008 0.97
38 Synthetic lethality-based targets for discovery of new cancer therapeutics. Cancer Genomics Proteomics 2011 0.92
39 Nuclei of chicken neurons in tissues and three-dimensional cell cultures are organized into distinct radial zones. Chromosome Res 2011 0.91
40 Dose-dependent regulation of target gene expression and cell proliferation by c-Myc levels. Transcription 2013 0.86
41 The tumor suppressor p53 connects ribosome biogenesis to cell cycle control: a double-edged sword. Oncotarget 2010 0.85
42 Emerging roles for RNA polymerase II CTD in Arabidopsis. Trends Plant Sci 2013 0.85
43 Rapid conditional knock-down-knock-in system for mammalian cells. Nucleic Acids Res 2006 0.83
44 Functional ribosome biogenesis is a prerequisite for p53 destabilization: impact of chemotherapy on nucleolar functions and RNA metabolism. Biol Chem 2013 0.82
45 Tyrosine-1 and threonine-4 phosphorylation marks complete the RNA polymerase II CTD phospho-code. RNA Biol 2012 0.82
46 The CALM and CALM/AF10 interactor CATS is a marker for proliferation. Mol Oncol 2008 0.82
47 Cyclin-dependent kinase 9 links RNA polymerase II transcription to processing of ribosomal RNA. J Biol Chem 2013 0.80
48 Myb-binding protein 1a (Mybbp1a) regulates levels and processing of pre-ribosomal RNA. J Biol Chem 2012 0.80
49 Notch1, Notch2, and Epstein-Barr virus-encoded nuclear antigen 2 signaling differentially affects proliferation and survival of Epstein-Barr virus-infected B cells. Blood 2009 0.80
50 Epstein-Barr virus antagonizes the antiproliferative activity of transforming growth factor-beta but does not abolish its signaling. Int J Cancer 2002 0.76