1
|
Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7.
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Science
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2007
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4.18
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2
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Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression.
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Science
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2007
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3.36
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3
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Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters.
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Nat Struct Mol Biol
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2011
|
2.79
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4
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TFIIH kinase places bivalent marks on the carboxy-terminal domain of RNA polymerase II.
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Mol Cell
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2009
|
2.61
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5
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H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex.
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Mol Cell
|
2007
|
2.32
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6
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CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II.
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Science
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2012
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2.05
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7
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Chemotherapeutic drugs inhibit ribosome biogenesis at various levels.
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J Biol Chem
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2010
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2.00
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8
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Dissection of transcriptional programmes in response to serum and c-Myc in a human B-cell line.
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Oncogene
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2005
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1.93
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9
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Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36.
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Nat Struct Mol Biol
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2011
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1.85
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10
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Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs.
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Cell Stem Cell
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2012
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1.80
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11
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A role for c-Myc in the regulation of ribosomal RNA processing.
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Nucleic Acids Res
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2003
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1.80
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12
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Chemical-genomic dissection of the CTD code.
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Nat Struct Mol Biol
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2010
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1.76
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13
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Dynamic phosphorylation patterns of RNA polymerase II CTD during transcription.
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Biochim Biophys Acta
|
2012
|
1.73
|
14
|
Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation.
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J Cell Biol
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2005
|
1.69
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15
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CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3'-end processing.
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EMBO Rep
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2009
|
1.69
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16
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Molecular evolution of the RNA polymerase II CTD.
|
Trends Genet
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2008
|
1.64
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17
|
Role of the mammalian RNA polymerase II C-terminal domain (CTD) nonconsensus repeats in CTD stability and cell proliferation.
|
Mol Cell Biol
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2005
|
1.55
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18
|
Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation.
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EMBO J
|
2012
|
1.55
|
19
|
The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing.
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EMBO Rep
|
2008
|
1.47
|
20
|
Latent membrane protein 1 of Epstein-Barr virus coordinately regulates proliferation with control of apoptosis.
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Oncogene
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2005
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1.47
|
21
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Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development.
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EMBO J
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2011
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1.41
|
22
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Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex.
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Nucleic Acids Res
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2006
|
1.41
|
23
|
Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules.
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Chem Biol
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2006
|
1.35
|
24
|
Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit.
|
Mol Cell Biol
|
2007
|
1.31
|
25
|
Defects in 18 S or 28 S rRNA processing activate the p53 pathway.
|
J Biol Chem
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2010
|
1.30
|
26
|
Ultrashort and progressive 4sU-tagging reveals key characteristics of RNA processing at nucleotide resolution.
|
Genome Res
|
2012
|
1.24
|
27
|
The last CTD repeat of the mammalian RNA polymerase II large subunit is important for its stability.
|
Nucleic Acids Res
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2004
|
1.23
|
28
|
Interferon antagonist NSs of La Crosse virus triggers a DNA damage response-like degradation of transcribing RNA polymerase II.
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J Biol Chem
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2010
|
1.17
|
29
|
In vivo live imaging of RNA polymerase II transcription factories in primary cells.
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Genes Dev
|
2013
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1.12
|
30
|
RNA polymerase II C-terminal heptarepeat domain Ser-7 phosphorylation is established in a mediator-dependent fashion.
|
J Biol Chem
|
2009
|
1.12
|
31
|
C-myc activation impairs the NF-kappaB and the interferon response: implications for the pathogenesis of Burkitt's lymphoma.
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Int J Cancer
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2007
|
1.11
|
32
|
Estrogen-dependent gene transcription in human breast cancer cells relies upon proteasome-dependent monoubiquitination of histone H2B.
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Cancer Res
|
2011
|
1.08
|
33
|
CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo.
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Nucleic Acids Res
|
2012
|
1.05
|
34
|
Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription.
|
Nat Cell Biol
|
2011
|
1.04
|
35
|
Phosphorylation by cyclin-dependent kinase-9 controls ubiquitin-conjugating enzyme-2A function.
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Cell Cycle
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2012
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1.01
|
36
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The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing.
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Nucleic Acids Res
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2006
|
0.97
|
37
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The nuclear organization of Polycomb/Trithorax group response elements in larval tissues of Drosophila melanogaster.
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Chromosome Res
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2008
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0.97
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38
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Synthetic lethality-based targets for discovery of new cancer therapeutics.
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Cancer Genomics Proteomics
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2011
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0.92
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39
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Nuclei of chicken neurons in tissues and three-dimensional cell cultures are organized into distinct radial zones.
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Chromosome Res
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2011
|
0.91
|
40
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Dose-dependent regulation of target gene expression and cell proliferation by c-Myc levels.
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Transcription
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2013
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0.86
|
41
|
The tumor suppressor p53 connects ribosome biogenesis to cell cycle control: a double-edged sword.
|
Oncotarget
|
2010
|
0.85
|
42
|
Emerging roles for RNA polymerase II CTD in Arabidopsis.
|
Trends Plant Sci
|
2013
|
0.85
|
43
|
Rapid conditional knock-down-knock-in system for mammalian cells.
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Nucleic Acids Res
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2006
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0.83
|
44
|
Functional ribosome biogenesis is a prerequisite for p53 destabilization: impact of chemotherapy on nucleolar functions and RNA metabolism.
|
Biol Chem
|
2013
|
0.82
|
45
|
Tyrosine-1 and threonine-4 phosphorylation marks complete the RNA polymerase II CTD phospho-code.
|
RNA Biol
|
2012
|
0.82
|
46
|
The CALM and CALM/AF10 interactor CATS is a marker for proliferation.
|
Mol Oncol
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2008
|
0.82
|
47
|
Cyclin-dependent kinase 9 links RNA polymerase II transcription to processing of ribosomal RNA.
|
J Biol Chem
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2013
|
0.80
|
48
|
Myb-binding protein 1a (Mybbp1a) regulates levels and processing of pre-ribosomal RNA.
|
J Biol Chem
|
2012
|
0.80
|
49
|
Notch1, Notch2, and Epstein-Barr virus-encoded nuclear antigen 2 signaling differentially affects proliferation and survival of Epstein-Barr virus-infected B cells.
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Blood
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2009
|
0.80
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50
|
Epstein-Barr virus antagonizes the antiproliferative activity of transforming growth factor-beta but does not abolish its signaling.
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Int J Cancer
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2002
|
0.76
|