Published in Oncogene on March 03, 2005
The coupling of synthesis and partitioning of EBV's plasmid replicon is revealed in live cells. EMBO J (2007) 2.71
Why do viruses cause cancer? Highlights of the first century of human tumour virology. Nat Rev Cancer (2010) 2.68
Epstein-Barr virus provides a new paradigm: a requirement for the immediate inhibition of apoptosis. PLoS Biol (2005) 2.08
Epstein-Barr virus-induced miR-155 attenuates NF-kappaB signaling and stabilizes latent virus persistence. J Virol (2008) 1.86
Transcriptional activation by EBV nuclear antigen 1 is essential for the expression of EBV's transforming genes. Proc Natl Acad Sci U S A (2006) 1.81
Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival. Blood (2007) 1.50
Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication. Cell Host Microbe (2011) 1.43
The LMP1 oncogene of EBV activates PERK and the unfolded protein response to drive its own synthesis. Blood (2007) 1.32
Regulation of Epstein-Barr virus latency type by the chromatin boundary factor CTCF. J Virol (2006) 1.24
Rescue of "crippled" germinal center B cells from apoptosis by Epstein-Barr virus. Blood (2005) 1.18
c-Myc and Rel/NF-kappaB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells. J Virol (2009) 1.14
How does Epstein-Barr virus (EBV) complement the activation of Myc in the pathogenesis of Burkitt's lymphoma? Semin Cancer Biol (2009) 1.13
Cellular target genes of Epstein-Barr virus nuclear antigen 2. J Virol (2006) 1.10
Epstein-barr virus-induced resistance to drugs that activate the mitotic spindle assembly checkpoint in Burkitt's lymphoma cells. J Virol (2006) 1.07
The latent membrane protein 1 (LMP1) oncogene of Epstein-Barr virus can simultaneously induce and inhibit apoptosis in B cells. J Virol (2012) 1.04
Regulation of the retinoblastoma proteins by the human herpesviruses. Cell Div (2009) 1.02
Proof for EBV's sustaining role in Burkitt's lymphomas. Semin Cancer Biol (2009) 0.99
Zinc coordination is required for and regulates transcription activation by Epstein-Barr nuclear antigen 1. PLoS Pathog (2009) 0.96
The A20 deubiquitinase activity negatively regulates LMP1 activation of IRF7. J Virol (2010) 0.96
Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation. Blood (2015) 0.94
TRAF5 is a critical mediator of in vitro signals and in vivo functions of LMP1, the viral oncogenic mimic of CD40. Proc Natl Acad Sci U S A (2009) 0.94
The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor. PLoS Biol (2012) 0.94
In nasopharyngeal carcinoma cells, Epstein-Barr virus LMP1 interacts with galectin 9 in membrane raft elements resistant to simvastatin. J Virol (2005) 0.94
A membrane leucine heptad contributes to trafficking, signaling, and transformation by latent membrane protein 1. J Virol (2007) 0.90
Correlation of Epstein-Barr virus and its encoded proteins with Helicobacter pylori and expression of c-met and c-myc in gastric carcinoma. World J Gastroenterol (2006) 0.89
Heat shock protein 90 inhibitors repress latent membrane protein 1 (LMP1) expression and proliferation of Epstein-Barr virus-positive natural killer cell lymphoma. PLoS One (2013) 0.86
Oxysterol-EBI2 signaling in immune regulation and viral infection. Eur J Immunol (2014) 0.84
Potential cellular functions of Epstein-Barr Nuclear Antigen 1 (EBNA1) of Epstein-Barr Virus. Viruses (2013) 0.84
Emerging roles of small Epstein-Barr virus derived non-coding RNAs in epithelial malignancy. Int J Mol Sci (2013) 0.83
TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation. PLoS Pathog (2015) 0.81
The landscape of host transcriptional response programs commonly perturbed by bacterial pathogens: towards host-oriented broad-spectrum drug targets. PLoS One (2013) 0.79
Induction of Epstein-Barr Virus Oncoprotein LMP1 by Transcription Factors AP-2 and Early B Cell Factor. J Virol (2016) 0.78
The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-κB in lymphocytes and contributes to their invasive migration. Cell Commun Signal (2014) 0.78
c-Rel deficiency increases caspase-4 expression and leads to ER stress and necrosis in EBV-transformed cells. PLoS One (2011) 0.77
The Modulation of Apoptotic Pathways by Gammaherpesviruses. Front Microbiol (2016) 0.76
Intrafollicular Epstein-Barr virus-positive large B cell lymphoma. A variant of "germinotropic" lymphoproliferative disorder. Virchows Arch (2016) 0.76
RUNX3 is oncogenic in natural killer/T-cell lymphoma and is transcriptionally regulated by MYC. Leukemia (2017) 0.76
How human tumor viruses make use of autophagy. Cells (2012) 0.76
Castration resistance in prostate cancer is mediated by the kinase NEK6. Cancer Res (2016) 0.75
[Epstein-Barr virus-associated lymphoproliferations and lymphomas]. Pathologe (2013) 0.75
Progression of understanding for the role of Epstein-Barr virus and management of nasopharyngeal carcinoma. Cancer Metastasis Rev (2017) 0.75
Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host. Science (2006) 6.47
Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7. Science (2007) 4.18
MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins. Proc Natl Acad Sci U S A (2008) 4.06
Nuclear signalling by tumour-associated antigen EpCAM. Nat Cell Biol (2009) 4.05
Serine-7 of the RNA polymerase II CTD is specifically required for snRNA gene expression. Science (2007) 3.36
The emerging role of EpCAM in cancer and stem cell signaling. Cancer Res (2009) 3.25
Comparison of gene expression profiles between human and mouse monocyte subsets. Blood (2009) 3.15
High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay. RNA (2008) 3.13
Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation. Science (2003) 3.00
Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters. Nat Struct Mol Biol (2011) 2.79
The coupling of synthesis and partitioning of EBV's plasmid replicon is revealed in live cells. EMBO J (2007) 2.71
The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation. Oncogene (2004) 2.67
TFIIH kinase places bivalent marks on the carboxy-terminal domain of RNA polymerase II. Mol Cell (2009) 2.61
H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex. Mol Cell (2007) 2.32
Epstein-Barr virus provides a new paradigm: a requirement for the immediate inhibition of apoptosis. PLoS Biol (2005) 2.08
CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II. Science (2012) 2.05
Chemotherapeutic drugs inhibit ribosome biogenesis at various levels. J Biol Chem (2010) 2.00
Dissection of transcriptional programmes in response to serum and c-Myc in a human B-cell line. Oncogene (2005) 1.93
Systematic analysis of viral and cellular microRNA targets in cells latently infected with human gamma-herpesviruses by RISC immunoprecipitation assay. Cell Host Microbe (2010) 1.91
Conditional immortalization of human B cells by CD40 ligation. PLoS One (2008) 1.89
Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance. Nat Immunol (2010) 1.89
Dynamics of adaptive microevolution of hypermutable Pseudomonas aeruginosa during chronic pulmonary infection in patients with cystic fibrosis. J Infect Dis (2009) 1.87
Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36. Nat Struct Mol Biol (2011) 1.85
Transcriptional activation by EBV nuclear antigen 1 is essential for the expression of EBV's transforming genes. Proc Natl Acad Sci U S A (2006) 1.81
Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs. Cell Stem Cell (2012) 1.80
Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells. PLoS Pathog (2010) 1.80
Strain-specific genes of Helicobacter pylori: genome evolution driven by a novel type IV secretion system and genomic island transfer. Nucleic Acids Res (2010) 1.80
A role for c-Myc in the regulation of ribosomal RNA processing. Nucleic Acids Res (2003) 1.80
The microRNAs of Epstein-Barr Virus are expressed at dramatically differing levels among cell lines. Virology (2009) 1.79
Chemical-genomic dissection of the CTD code. Nat Struct Mol Biol (2010) 1.76
The EBV nuclear antigen 1 (EBNA1) enhances B cell immortalization several thousandfold. Proc Natl Acad Sci U S A (2003) 1.75
Lymphomas differ in their dependence on Epstein-Barr virus. Blood (2010) 1.74
Dynamic phosphorylation patterns of RNA polymerase II CTD during transcription. Biochim Biophys Acta (2012) 1.73
The plasmid replicon of Epstein-Barr virus: mechanistic insights into efficient, licensed, extrachromosomal replication in human cells. Plasmid (2007) 1.72
Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1β production. J Immunol (2012) 1.71
Epstein-Barr virus provides a survival factor to Burkitt's lymphomas. Proc Natl Acad Sci U S A (2003) 1.69
CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3'-end processing. EMBO Rep (2009) 1.69
Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation. J Cell Biol (2005) 1.69
Molecular evolution of the RNA polymerase II CTD. Trends Genet (2008) 1.64
Genome-wide expression profiling reveals EBV-associated inhibition of MHC class I expression in nasopharyngeal carcinoma. Cancer Res (2006) 1.62
Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus. J Cell Sci (2003) 1.62
Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis. Mol Cell Proteomics (2011) 1.59
Genetically determined susceptibility to tuberculosis in mice causally involves accelerated and enhanced recruitment of granulocytes. Infect Immun (2006) 1.57
Latent membrane protein 1 is critical for efficient growth transformation of human B cells by epstein-barr virus. Cancer Res (2003) 1.56
Role of the mammalian RNA polymerase II C-terminal domain (CTD) nonconsensus repeats in CTD stability and cell proliferation. Mol Cell Biol (2005) 1.55
Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation. EMBO J (2012) 1.55
Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival. Blood (2007) 1.50
EBNA-1, a bifunctional transcriptional activator. Mol Cell Biol (2003) 1.48
Treatment algorithms for chronic osteomyelitis. Dtsch Arztebl Int (2012) 1.47
The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing. EMBO Rep (2008) 1.47
CD8 T cell recognition of endogenously expressed epstein-barr virus nuclear antigen 1. J Exp Med (2004) 1.47
AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome. Proc Natl Acad Sci U S A (2009) 1.46
Negative regulation of the EGFR-MAPK cascade by actin-MAL-mediated Mig6/Errfi-1 induction. Mol Cell (2009) 1.44
Identification and functional analysis of tumor-infiltrating plasmacytoid dendritic cells in head and neck cancer. Cancer Res (2003) 1.44
Cystatin C modulates cerebral beta-amyloidosis. Nat Genet (2007) 1.42
Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2. Blood (2010) 1.42
Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development. EMBO J (2011) 1.41
On the abundance of EpCAM on cancer stem cells. Nat Rev Cancer (2009) 1.41
Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex. Nucleic Acids Res (2006) 1.41
Epstein-Barr virus mRNA export factor EB2 is essential for production of infectious virus. J Virol (2002) 1.36
Interaction between HMGA1a and the origin recognition complex creates site-specific replication origins. Proc Natl Acad Sci U S A (2008) 1.36
Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules. Chem Biol (2006) 1.35
Molecular signatures of self-renewal, differentiation, and lineage choice in multipotential hemopoietic progenitor cells in vitro. Mol Cell Biol (2004) 1.35
Effective and long-term control of EBV PTLD after transfer of peptide-selected T cells. Blood (2010) 1.35
Embryonic endothelial progenitor cells expressing a broad range of proangiogenic and remodeling factors enhance vascularization and tissue recovery in acute and chronic ischemia. FASEB J (2005) 1.33
Efficient isolation and gene expression profiling of small numbers of neural crest stem cells and developing Schwann cells. J Neurosci (2004) 1.33
CD44s and CD44v6 expression in head and neck epithelia. PLoS One (2008) 1.33
The LMP1 oncogene of EBV activates PERK and the unfolded protein response to drive its own synthesis. Blood (2007) 1.32
Interdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunit. Mol Cell Biol (2007) 1.31
EpCAM is involved in maintenance of the murine embryonic stem cell phenotype. Stem Cells (2009) 1.31
Defects in 18 S or 28 S rRNA processing activate the p53 pathway. J Biol Chem (2010) 1.30
Activation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein. J Virol (2003) 1.30
Common and unique gene expression signatures of human macrophages in response to four strains of Mycobacterium avium that differ in their growth and persistence characteristics. Infect Immun (2005) 1.29
CpG-methylation regulates a class of Epstein-Barr virus promoters. PLoS Pathog (2010) 1.28
Ultrashort and progressive 4sU-tagging reveals key characteristics of RNA processing at nucleotide resolution. Genome Res (2012) 1.24
The last CTD repeat of the mammalian RNA polymerase II large subunit is important for its stability. Nucleic Acids Res (2004) 1.23
CD40 and its viral mimic, LMP1: similar means to different ends. Cell Signal (2003) 1.22
Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease. Proc Natl Acad Sci U S A (2010) 1.21
AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer. J Exp Med (2013) 1.19
Rescue of "crippled" germinal center B cells from apoptosis by Epstein-Barr virus. Blood (2005) 1.18
Temperature-sensitive eIF5A mutant accumulates transcripts targeted to the nonsense-mediated decay pathway. J Biol Chem (2006) 1.18
Essential elements of a licensed, mammalian plasmid origin of DNA synthesis. Mol Cell Biol (2006) 1.18
Interferon antagonist NSs of La Crosse virus triggers a DNA damage response-like degradation of transcribing RNA polymerase II. J Biol Chem (2010) 1.17
High physiological levels of LMP1 result in phosphorylation of eIF2 alpha in Epstein-Barr virus-infected cells. J Virol (2004) 1.15
Initial activation of EpCAM cleavage via cell-to-cell contact. BMC Cancer (2009) 1.14
The proinflammatory cytokine-induced IRG1 protein associates with mitochondria. J Interferon Cytokine Res (2009) 1.13
In vivo live imaging of RNA polymerase II transcription factories in primary cells. Genes Dev (2013) 1.12
RNA polymerase II C-terminal heptarepeat domain Ser-7 phosphorylation is established in a mediator-dependent fashion. J Biol Chem (2009) 1.12
Transcript profiling of CD16-positive monocytes reveals a unique molecular fingerprint. Eur J Immunol (2012) 1.11
C-myc activation impairs the NF-kappaB and the interferon response: implications for the pathogenesis of Burkitt's lymphoma. Int J Cancer (2007) 1.11
Cellular target genes of Epstein-Barr virus nuclear antigen 2. J Virol (2006) 1.10
Epstein-Barr virus sustains Burkitt's lymphomas and Hodgkin's disease. Trends Mol Med (2004) 1.10
Coupled transcriptome and proteome analysis of human lymphotropic tumor viruses: insights on the detection and discovery of viral genes. BMC Genomics (2011) 1.09
Estrogen-dependent gene transcription in human breast cancer cells relies upon proteasome-dependent monoubiquitination of histone H2B. Cancer Res (2011) 1.08
The EBV immunoevasins vIL-10 and BNLF2a protect newly infected B cells from immune recognition and elimination. PLoS Pathog (2012) 1.08
Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A. Nucleic Acids Res (2006) 1.08