Published in Development on February 01, 2005
The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age. PLoS Biol (2007) 2.54
Multifactorial origins of heart and gut defects in nipbl-deficient zebrafish, a model of Cornelia de Lange Syndrome. PLoS Biol (2011) 1.77
Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube. Genes Dev (2010) 1.51
Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. BMC Genomics (2008) 1.35
Postmitotic specification of Drosophila insulinergic neurons from pioneer neurons. PLoS Biol (2008) 1.21
Probing the diversity of serotonin neurons. Philos Trans R Soc Lond B Biol Sci (2012) 1.14
Foxj1 regulates floor plate cilia architecture and modifies the response of cells to sonic hedgehog signalling. Development (2010) 1.13
Multiple roles for Med12 in vertebrate endoderm development. Dev Biol (2008) 1.06
Conservation and regulatory associations of a wide affinity range of mouse transcription factor binding sites. Genomics (2010) 1.02
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm. Dev Biol (2006) 0.98
Conserved and non-conserved enhancers direct tissue specific transcription in ancient germ layer specific developmental control genes. BMC Dev Biol (2011) 0.93
Genomewide expression profiling in the zebrafish embryo identifies target genes regulated by Hedgehog signaling during vertebrate development. Genetics (2006) 0.90
Glial cell development and function in zebrafish. Cold Spring Harb Perspect Biol (2014) 0.90
Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors. Development (2012) 0.89
Deep mRNA sequencing analysis to capture the transcriptome landscape of zebrafish embryos and larvae. PLoS One (2013) 0.86
A novel role for FOXA2 and SHH in organizing midbrain signaling centers. Dev Biol (2012) 0.82
Genetic dissection of myelinated axons in zebrafish. Curr Opin Neurobiol (2009) 0.82
Genes and signaling networks regulated during zebrafish optic vesicle morphogenesis. BMC Genomics (2014) 0.80
Complexity of cis-regulatory organization of six3a during forebrain and eye development in zebrafish. BMC Dev Biol (2010) 0.78
Selection Based on FOXA2 Expression Is Not Sufficient to Enrich for Dopamine Neurons From Human Pluripotent Stem Cells. Stem Cells Transl Med (2014) 0.78
Both ciliary and non-ciliary functions of Foxj1a confer Wnt/β-catenin signaling in zebrafish left-right patterning. Biol Open (2015) 0.77
Rasl11b knock down in zebrafish suppresses one-eyed-pinhead mutant phenotype. PLoS One (2008) 0.77
Copy number variants in patients with intellectual disability affect the regulation of ARX transcription factor gene. Hum Genet (2015) 0.77
Identification of proliferative progenitors associated with prominent postnatal growth of the pons. Nat Commun (2016) 0.75
Intraspinal serotonergic neurons consist of two, temporally distinct populations in developing zebrafish. Dev Neurobiol (2015) 0.75
FoxA4 favours notochord formation by inhibiting contiguous mesodermal fates and restricts anterior neural development in Xenopus embryos. PLoS One (2014) 0.75
Preservation of duplicate genes by complementary, degenerative mutations. Genetics (1999) 18.29
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine. Nature (2000) 10.04
Vertebrate genome evolution and the zebrafish gene map. Nat Genet (1998) 5.16
HNF-3 beta is essential for node and notochord formation in mouse development. Cell (1994) 4.08
Gli and hedgehog in cancer: tumours, embryos and stem cells. Nat Rev Cancer (2002) 3.91
A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell (1993) 3.90
The teratogenic Veratrum alkaloid cyclopamine inhibits sonic hedgehog signal transduction. Development (1998) 3.89
The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo. Cell (1994) 3.71
The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. Cell (2003) 3.66
Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog. Science (2003) 3.62
FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell (1998) 3.33
Visualization of cranial motor neurons in live transgenic zebrafish expressing green fluorescent protein under the control of the islet-1 promoter/enhancer. J Neurosci (2000) 3.24
A comparative map of the zebrafish genome. Genome Res (2000) 2.90
fork head domain genes in zebrafish. Dev Genes Evol (1998) 2.58
Patterning activities of vertebrate hedgehog proteins in the developing eye and brain. Curr Biol (1995) 2.54
Zebrafish smoothened functions in ventral neural tube specification and axon tract formation. Development (2001) 2.26
The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity. Development (2000) 2.25
Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans. Development (2003) 2.18
Hedgehog-Gli signalling and the growth of the brain. Nat Rev Neurosci (2002) 2.10
Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling. Nature (1998) 2.10
A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord. Genes Dev (2002) 2.09
Induction of midbrain dopaminergic neurons by Sonic hedgehog. Neuron (1995) 2.08
Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish. Development (1998) 2.08
Analysis of the zebrafish smoothened mutant reveals conserved and divergent functions of hedgehog activity. Development (2001) 2.05
Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation. Development (2004) 2.01
Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation. Cell (1998) 2.00
A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube. Mol Cell (2001) 1.99
A regulator of transcriptional elongation controls vertebrate neuronal development. Nature (2000) 1.87
olig2 is required for zebrafish primary motor neuron and oligodendrocyte development. Dev Biol (2002) 1.79
cyclops encodes a nodal-related factor involved in midline signaling. Proc Natl Acad Sci U S A (1998) 1.75
The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail. Development (1997) 1.73
Gli proteins and the control of spinal-cord patterning. EMBO Rep (2003) 1.68
A reference cross DNA panel for zebrafish (Danio rerio) anchored with simple sequence length polymorphisms. Development (1996) 1.67
HNF-3 beta as a regulator of floor plate development. Cell (1994) 1.66
Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain. Development (1995) 1.66
Mutations affecting development of the midline and general body shape during zebrafish embryogenesis. Development (1996) 1.65
Characterization of myelination in the developing zebrafish. Glia (2002) 1.64
Axial, a zebrafish gene expressed along the developing body axis, shows altered expression in cyclops mutant embryos. Genes Dev (1993) 1.62
Coordinated temporal and spatial control of motor neuron and serotonergic neuron generation from a common pool of CNS progenitors. Genes Dev (2003) 1.60
The development of a simple scaffold of axon tracts in the brain of the embryonic zebrafish, Brachydanio rerio. Development (1990) 1.54
Dopamine transporter expression distinguishes dopaminergic neurons from other catecholaminergic neurons in the developing zebrafish embryo. Mech Dev (2001) 1.54
Expression of a novel aristaless related homeobox gene 'Arx' in the vertebrate telencephalon, diencephalon and floor plate. Mech Dev (1997) 1.53
Regionalization of Sonic hedgehog transcription along the anteroposterior axis of the mouse central nervous system is regulated by Hnf3-dependent and -independent mechanisms. Development (1999) 1.52
The zebrafish T-box genes no tail and spadetail are required for development of trunk and tail mesoderm and medial floor plate. Development (2002) 1.41
Intronic enhancers control expression of zebrafish sonic hedgehog in floor plate and notochord. Development (1999) 1.39
The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system. Nature (1991) 1.39
The emergent design of the neural tube: prepattern, SHH morphogen and GLI code. Curr Opin Genet Dev (2003) 1.38
Distinct regulators of Shh transcription in the floor plate and notochord indicate separate origins for these tissues in the mouse node. Development (2003) 1.34
Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain. Neuron (1994) 1.31
The zebrafish forkhead transcription factor FoxH1/Fast1 is a modulator of nodal signaling required for organizer formation. Curr Biol (2000) 1.27
Expression and regulation of a netrin homologue in the zebrafish embryo. Mech Dev (1997) 1.24
Axon guidance at the midline choice point. Dev Dyn (2001) 1.19
Search for enhancers: teleost models in comparative genomic and transgenic analysis of cis regulatory elements. Bioessays (2002) 1.17
Mindin/F-spondin family: novel ECM proteins expressed in the zebrafish embryonic axis. Dev Biol (1997) 1.16
Two distinct cell populations in the floor plate of the zebrafish are induced by different pathways. Dev Biol (2000) 1.12
Direct action of the nodal-related signal cyclops in induction of sonic hedgehog in the ventral midline of the CNS. Development (2000) 1.10
Fast1 is required for the development of dorsal axial structures in zebrafish. Curr Biol (2000) 1.07
Hedgehog and retinoid signalling confines nkx2.2b expression to the lateral floor plate of the zebrafish trunk. Mech Dev (2005) 1.07
Fate maps of the zebrafish embryo. Curr Opin Genet Dev (1995) 1.02
Vertebrate floor-plate specification: variations on common themes. Trends Genet (2004) 1.01
Hedgehog and Fgf signaling pathways regulate the development of tphR-expressing serotonergic raphe neurons in zebrafish embryos. J Neurobiol (2004) 1.00
Axial (HNF3beta) and retinoic acid receptors are regulators of the zebrafish sonic hedgehog promoter. EMBO J (1997) 0.99
Expression profiling and comparative genomics identify a conserved regulatory region controlling midline expression in the zebrafish embryo. Genome Res (2004) 0.98
one-eyed pinhead is required for development of the ventral midline of the zebrafish (Danio rerio) neural tube. Genes Funct (1997) 0.95
Dual origin of the floor plate in the avian embryo. Development (2002) 0.95
Maintenance of the specification of the anterior definitive endoderm and forebrain depends on the axial mesendoderm: a study using HNF3beta/Foxa2 conditional mutants. Dev Biol (2002) 0.93
Restrictions to floor plate induction by hedgehog and winged-helix genes in the neural tube of frog embryos. Mol Cell Neurosci (1995) 0.93
her9 promotes floor plate development in zebrafish. Dev Dyn (2005) 0.91
Homologues of c-hairy1 (her9) and lunatic fringe in zebrafish are expressed in the developing central nervous system, but not in the presomitic mesoderm. Dev Genes Evol (2001) 0.91
A temperature-sensitive mutation in the nodal-related gene cyclops reveals that the floor plate is induced during gastrulation in zebrafish. Development (2003) 0.90
Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction. Development (2003) 0.89
Floor plate develops upon depletion of tiggy-winkle and sonic hedgehog. Genesis (2001) 0.89
Expression of genes encoding the collagen-binding heat shock protein (Hsp47) and type II collagen in developing zebrafish embryos. Mech Dev (1997) 0.87
A floor plate enhancer of the zebrafish netrin1 gene requires Cyclops (Nodal) signalling and the winged helix transcription factor FoxA2. Dev Biol (2002) 0.86
Cyclops-independent floor plate differentiation in zebrafish embryos. Dev Dyn (2003) 0.81
Cloning of two tryptophan hydroxylase genes expressed in the diencephalon of the developing zebrafish brain. Gene Expr Patterns (2002) 0.80
The zebrafish reference genome sequence and its relationship to the human genome. Nature (2013) 8.52
SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes. Neuron (2006) 3.96
Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction. Blood (2010) 3.82
Migration of zebrafish primordial germ cells: a role for myosin contraction and cytoplasmic flow. Dev Cell (2006) 3.39
The zebrafish gene map defines ancestral vertebrate chromosomes. Genome Res (2005) 3.18
A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor. Nature (2002) 3.15
Zebrafish as a model vertebrate for investigating chemical toxicity. Toxicol Sci (2005) 3.08
Molecular genetics of axis formation in zebrafish. Annu Rev Genet (2005) 3.06
MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system. Genome Biol (2007) 3.05
Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells. Nature (2004) 3.02
In vivo protein trapping produces a functional expression codex of the vertebrate proteome. Nat Methods (2011) 2.85
A G protein-coupled receptor is essential for Schwann cells to initiate myelination. Science (2009) 2.77
Wnt11 functions in gastrulation by controlling cell cohesion through Rab5c and E-cadherin. Dev Cell (2005) 2.62
erbb3 and erbb2 are essential for schwann cell migration and myelination in zebrafish. Curr Biol (2005) 2.55
Proteomics of early zebrafish embryos. BMC Dev Biol (2006) 2.36
Hedgehog signaling is required for cranial neural crest morphogenesis and chondrogenesis at the midline in the zebrafish skull. Development (2005) 2.36
Early steps in the development of the forebrain. Dev Cell (2004) 2.34
Single-cell force spectroscopy. J Cell Sci (2008) 2.29
Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish. Development (2003) 2.26
The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation. Nat Genet (2010) 2.25
Rapid mapping of zebrafish mutations with SNPs and oligonucleotide microarrays. Genome Res (2002) 2.22
Diabetes prevention in the real world: effectiveness of pragmatic lifestyle interventions for the prevention of type 2 diabetes and of the impact of adherence to guideline recommendations: a systematic review and meta-analysis. Diabetes Care (2014) 2.21
Cohesin-dependent regulation of Runx genes. Development (2007) 2.15
Fgf10 regulates hepatopancreatic ductal system patterning and differentiation. Nat Genet (2007) 2.14
Adhesion functions in cell sorting by mechanically coupling the cortices of adhering cells. Science (2012) 2.12
The Bmp gradient of the zebrafish gastrula guides migrating lateral cells by regulating cell-cell adhesion. Curr Biol (2007) 2.10
Mutations in radial spoke head protein genes RSPH9 and RSPH4A cause primary ciliary dyskinesia with central-microtubular-pair abnormalities. Am J Hum Genet (2009) 2.07
beamter/deltaC and the role of Notch ligands in the zebrafish somite segmentation, hindbrain neurogenesis and hypochord differentiation. Dev Biol (2005) 2.06
A role for Rho GTPases and cell-cell adhesion in single-cell motility in vivo. Nat Cell Biol (2009) 2.05
Laterotopic representation of left-right information onto the dorso-ventral axis of a zebrafish midbrain target nucleus. Curr Biol (2005) 2.03
Control of directed cell migration in vivo by membrane-to-cortex attachment. PLoS Biol (2010) 2.03
Wise, a context-dependent activator and inhibitor of Wnt signalling. Development (2003) 1.97
Aryl hydrocarbon receptor 2 mediates 2,3,7,8-tetrachlorodibenzo-p-dioxin developmental toxicity in zebrafish. Toxicol Sci (2003) 1.90
Forces driving epithelial spreading in zebrafish gastrulation. Science (2012) 1.89
fsi zebrafish show concordant reversal of laterality of viscera, neuroanatomy, and a subset of behavioral responses. Curr Biol (2005) 1.86
Scube/You activity mediates release of dually lipid-modified Hedgehog signal in soluble form. Genes Dev (2012) 1.84
N-cadherin mediates retinal lamination, maintenance of forebrain compartments and patterning of retinal neurites. Development (2003) 1.79
Multiple regulatory elements with spatially and temporally distinct activities control neurogenin1 expression in primary neurons of the zebrafish embryo. Mech Dev (2003) 1.79
Multifactorial origins of heart and gut defects in nipbl-deficient zebrafish, a model of Cornelia de Lange Syndrome. PLoS Biol (2011) 1.77
Gpr126 is essential for peripheral nerve development and myelination in mammals. Development (2011) 1.77
her1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somitogenesis. Development (2002) 1.77
Coordinated cell-shape changes control epithelial movement in zebrafish and Drosophila. Development (2006) 1.76
Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development (2003) 1.76
The habenular nuclei: a conserved asymmetric relay station in the vertebrate brain. Philos Trans R Soc Lond B Biol Sci (2009) 1.72
Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo. PLoS Biol (2007) 1.68
Wnt11 controls cell contact persistence by local accumulation of Frizzled 7 at the plasma membrane. J Cell Biol (2006) 1.67
The UCS factor Steif/Unc-45b interacts with the heat shock protein Hsp90a during myofibrillogenesis. Dev Biol (2007) 1.65
Conserved and acquired features of adult neurogenesis in the zebrafish telencephalon. Dev Biol (2006) 1.64
Local tissue interactions across the dorsal midline of the forebrain establish CNS laterality. Neuron (2003) 1.63
Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/beta-catenin pathway. Neuron (2005) 1.62
A genetic screen identifies genes essential for development of myelinated axons in zebrafish. Dev Biol (2006) 1.60
Aryl hydrocarbon receptor-independent toxicity of weathered crude oil during fish development. Environ Health Perspect (2005) 1.57
Axon sorting in the optic tract requires HSPG synthesis by ext2 (dackel) and extl3 (boxer). Neuron (2004) 1.56
Distinct roles for Fgf, Wnt and retinoic acid in posteriorizing the neural ectoderm. Development (2002) 1.54
parachute/n-cadherin is required for morphogenesis and maintained integrity of the zebrafish neural tube. Development (2002) 1.53
The ATPase-dependent chaperoning activity of Hsp90a regulates thick filament formation and integration during skeletal muscle myofibrillogenesis. Development (2008) 1.52
Zebrafish atlastin controls motility and spinal motor axon architecture via inhibition of the BMP pathway. Nat Neurosci (2010) 1.52
Shield formation at the onset of zebrafish gastrulation. Development (2005) 1.52
Zebrafish embryos as an alternative to animal experiments--a commentary on the definition of the onset of protected life stages in animal welfare regulations. Reprod Toxicol (2011) 1.51
Morphogenesis underlying the development of the everted teleost telencephalon. Neural Dev (2012) 1.51
Phosphoinositide 3-kinase is required for process outgrowth and cell polarization of gastrulating mesendodermal cells. Curr Biol (2003) 1.50
Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cells. Development (2006) 1.50
Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud. Development (2002) 1.50
Planar cell polarization requires Widerborst, a B' regulatory subunit of protein phosphatase 2A. Development (2002) 1.48
Quantitative differences in tissue surface tension influence zebrafish germ layer positioning. HFSP J (2008) 1.47
Convergent extension movements and ciliary function are mediated by ofd1, a zebrafish orthologue of the human oral-facial-digital type 1 syndrome gene. Hum Mol Genet (2008) 1.46
Eph/Ephrin signaling regulates the mesenchymal-to-epithelial transition of the paraxial mesoderm during somite morphogenesis. Curr Biol (2003) 1.45
Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation. Development (2003) 1.45
Cranial neural crest and development of the head skeleton. Adv Exp Med Biol (2006) 1.44
Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo. Nat Neurosci (2002) 1.44
Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity. Development (2003) 1.43
Sonic hedgehog, secreted by amacrine cells, acts as a short-range signal to direct differentiation and lamination in the zebrafish retina. Development (2004) 1.43
The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans. Development (2003) 1.43
Measuring cell adhesion forces of primary gastrulating cells from zebrafish using atomic force microscopy. J Cell Sci (2005) 1.42
Leukocyte tyrosine kinase functions in pigment cell development. PLoS Genet (2008) 1.41