Jonathan R T Lakey

Author PubWeight™ 83.68‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 International trial of the Edmonton protocol for islet transplantation. N Engl J Med 2006 13.43
2 Five-year follow-up after clinical islet transplantation. Diabetes 2005 7.86
3 Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas. Nat Med 2006 2.41
4 Successful islet transplantation: continued insulin reserve provides long-term glycemic control. Diabetes 2002 2.36
5 A human beta-cell line for transplantation therapy to control type 1 diabetes. Nat Biotechnol 2005 2.12
6 Islet graft assessment in the Edmonton Protocol: implications for predicting long-term clinical outcome. Diabetes 2004 1.98
7 Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet {beta}-cells from pancreatic duct cells and an increase in functional {beta}-cell mass. J Clin Endocrinol Metab 2005 1.61
8 Prevalence of hepatic steatosis after islet transplantation and its relation to graft function. Diabetes 2004 1.46
9 A novel approach to increase human islet cell mass while preserving beta-cell function. Diabetes 2002 1.43
10 Beta-score: an assessment of beta-cell function after islet transplantation. Diabetes Care 2005 1.35
11 Percutaneous transhepatic pancreatic islet cell transplantation in type 1 diabetes mellitus: radiologic aspects. Radiology 2003 1.34
12 Strategic opportunities in clinical islet transplantation. Transplantation 2005 1.34
13 Intrahepatic islet transplantation in type 1 diabetic patients does not restore hypoglycemic hormonal counterregulation or symptom recognition after insulin independence. Diabetes 2002 1.32
14 Expansion of mesenchymal stem cells from human pancreatic ductal epithelium. Lab Invest 2006 1.28
15 Combination therapy with glucagon-like peptide-1 and gastrin induces beta-cell neogenesis from pancreatic duct cells in human islets transplanted in immunodeficient diabetic mice. Cell Transplant 2008 1.16
16 Enhancing the success of human islet isolation through optimization and characterization of pancreas dissociation enzyme. Am J Transplant 2007 1.14
17 The portal immunosuppressive storm: relevance to islet transplantation? Ther Drug Monit 2005 1.14
18 Estimation of pancreas weight from donor variables. Cell Transplant 2006 1.13
19 Synaptosome-associated protein of 25 kilodaltons modulates Kv2.1 voltage-dependent K(+) channels in neuroendocrine islet beta-cells through an interaction with the channel N terminus. Mol Endocrinol 2002 1.13
20 Islet isolation and transplantation outcomes of pancreas preserved with University of Wisconsin solution versus two-layer method using preoxygenated perfluorocarbon. Transplantation 2006 1.12
21 XIAP overexpression in human islets prevents early posttransplant apoptosis and reduces the islet mass needed to treat diabetes. Diabetes 2005 1.12
22 Assessment of glycemic control after islet transplantation using the continuous glucose monitor in insulin-independent versus insulin-requiring type 1 diabetes subjects. Diabetes Technol Ther 2006 1.08
23 The standardization of pancreatic donors for islet isolations. Transplantation 2005 1.07
24 Factors influencing the collagenase digestion phase of human islet isolation. Transplantation 2007 1.03
25 Comparison of aortic valve allograft decellularization techniques in the rat. J Biomed Mater Res A 2006 1.01
26 Estrogen can prevent or reverse obesity and diabetes in mice expressing human islet amyloid polypeptide. Diabetes 2002 1.00
27 Decellularization reduces the immune response to aortic valve allografts in the rat. J Thorac Cardiovasc Surg 2005 0.95
28 Pancreas divisum: a study of the cadaveric donor pancreas for islet isolation. Pancreas 2005 0.94
29 Changes in liver enzymes after clinical islet transplantation. Transplantation 2003 0.92
30 Detection of microbial contamination during human islet isolation. Cell Transplant 2007 0.90
31 Use of an allograft patch in repair of hypoplastic left heart syndrome may complicate future transplantation. Eur J Cardiothorac Surg 2005 0.90
32 Enriched human pancreatic ductal cultures obtained from selective death of acinar cells express pancreatic and duodenal homeobox gene-1 age-dependently. Rev Diabet Stud 2004 0.90
33 Clinical islet transplant: current and future directions towards tolerance. Immunol Rev 2003 0.90
34 Influence of pancreas preservation on human islet isolation outcomes: impact of the two-layer method. Transplantation 2004 0.90
35 Pulsatile intravenous insulin therapy: the best practice to reverse diabetes complications? Med Hypotheses 2009 0.89
36 Pancreatic islet autotransplantation with completion pancreatectomy in the management of uncontrolled pancreatic fistula after whipple resection for ampullary adenocarcinoma. Pancreas 2006 0.87
37 Human islet transplantation from pancreases with prolonged cold ischemia using additional preservation by the two-layer (UW solution/perfluorochemical) cold-storage method. Transplantation 2002 0.87
38 Clinical islet transplantation at the University of Alberta--the Edmonton experience. Clin Transpl 2005 0.86
39 Maintenance of mouse, rat, and pig pancreatic islet functions by coculture with human islet-derived fibroblasts. Cell Transplant 2006 0.86
40 Quantitative assessment of collagenase blends for human islet isolation. Transplantation 2005 0.86
41 In vitro maturation of viable islets from partially digested young pig pancreas. Cell Transplant 2013 0.84
42 Evaluation of Pefabloc as a serine protease inhibitor during human-islet isolation. Transplantation 2003 0.84
43 The use of an approved biodegradable polymer scaffold as a solid support system for improvement of islet engraftment. Artif Organs 2008 0.82
44 The current situation in human pancreatic islet transplantation: problems and prospects. J Artif Organs 2004 0.82
45 Cross-sectional and prospective association between proinsulin secretion and graft function after clinical islet transplantation. Transplantation 2004 0.82
46 Alleviating ischemia-reperfusion injury in small bowel. Am J Transplant 2004 0.82
47 Current status of islet encapsulation. Cell Transplant 2013 0.81
48 Islet auto-transplantation into an omental or splenic site results in a normal beta cell but abnormal alpha cell response to mild non-insulin-induced hypoglycemia. Am J Transplant 2005 0.81
49 Endogenous pancreatic enzyme activity levels show no significant effect on human islet isolation yield. Cell Transplant 2004 0.81
50 Development of a novel beta-cell specific promoter system for the identification of insulin-producing cells in in vitro cell cultures. Exp Cell Res 2006 0.80
51 Compaction of islets is detrimental to transplant outcome in mice. Transplantation 2006 0.80
52 An evaluation of endogenous pancreatic enzyme levels after human islet isolation. Pancreas 2003 0.79
53 Stem cell sources for clinical islet transplantation in type 1 diabetes: embryonic and adult stem cells. Med Hypotheses 2006 0.79
54 Defining optimal immunosuppression for islet transplantation based on reduced diabetogenicity in canine islet autografts. Transplantation 2002 0.79
55 Maintenance of glucose-sensitive insulin secretion of cryopreserved human islets with University of Wisconsin solution and ascorbic acid-2 glucoside. Artif Organs 2004 0.79
56 Short-term storage of the ischemically damaged human pancreas by the two-layer method prior to islet isolation. Cell Transplant 2004 0.78
57 Ameliorating injury during preservation and isolation of human islets using the two-layer method with perfluorocarbon and UW solution. Cell Transplant 2006 0.78
58 Sirolimus-induced ulceration of the small bowel in islet transplant recipients: report of two cases. Am J Transplant 2005 0.78
59 Noninvasive evaluation of the vascular response to transplantation of alginate encapsulated islets using the dorsal skin-fold model. Biomaterials 2013 0.76
60 Islet isolation and transplantation from an annular pancreas: a case report. JOP 2005 0.76
61 The Efficacy of a Prevascularized, Retrievable Poly(D,L,-lactide-co-ε-caprolactone) Subcutaneous Scaffold as Transplantation Site for Pancreatic Islets. Transplantation 2017 0.75
62 Oxygen and pancreas preservation. Transplantation 2006 0.75
63 Comparison of cooling systems during islet purification. Cell Transplant 2006 0.75
64 Evaluating the effect of serine proteases on collagenase activity during human islet isolation. Cell Transplant 2002 0.75
65 Pancreatic duct: A suitable route to oxygenate tissue during pancreas hypothermic preservation? Transpl Immunol 2009 0.75
66 A novel technique of hypothermic luminal perfusion for small bowel preservation. Transplantation 2003 0.75
67 DEVELOPING A RAPID ALGORITHM TO ENABLE RAPID CHARACTERIZATION OF ALGINATE MICROCAPSULES. Cell Transplant 2016 0.75