V J Feron

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Nitrate, nitrite and N-nitroso compounds. Eur J Pharmacol 1994 1.81
2 Sensory irritation to mixtures of formaldehyde, acrolein, and acetaldehyde in rats. Arch Toxicol 1996 1.62
3 Two-year feeding amd multigeneration studies in rats on five chemically modified starches. Food Cosmet Toxicol 1974 1.42
4 Procedures for health risk assessment in Europe. Regul Toxicol Pharmacol 2001 1.41
5 Subacute toxicity of a mixture of nine chemicals in rats: detecting interactive effects with a fractionated two-level factorial design. Fundam Appl Toxicol 1997 1.18
6 Nasal tumours in rats after severe injury to the nasal mucosa and prolonged exposure to 10 ppm formaldehyde. J Appl Toxicol 1989 1.17
7 Inhalation toxicity of acetaldehyde in rats. III. Carcinogenicity study. Toxicology 1986 1.09
8 Respiratory tract tumors in hamsters after intratracheal instillations of benzo(a)pyrene alone and with furfural. Cancer Res 1972 1.05
9 Toxicology of simple and complex mixtures. Trends Pharmacol Sci 2001 1.03
10 Toxicological evaluation and risk assessment of chemical mixtures. Crit Rev Toxicol 1998 1.02
11 Changes in the nasal epithelium of rats exposed by inhalation to mixtures of formaldehyde, acetaldehyde, and acrolein. Fundam Appl Toxicol 1996 1.01
12 Safety assessment of allylalkoxybenzene derivatives used as flavouring substances - methyl eugenol and estragole. Food Chem Toxicol 2002 1.00
13 Subchronic inhalation toxicity of amorphous silicas and quartz dust in rats. Food Chem Toxicol 1991 0.97
14 The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. Flavor and Extract Manufacturers Association. Food Chem Toxicol 2002 0.96
15 Respiratory tract tumours in hamsters exposed to acetaldehyde vapour alone or simultaneously to benzo(a)pyrene or diethylnitrosamine. Eur J Cancer Clin Oncol 1982 0.95
16 Repeated exposure to acrolein vapour: subacute studies in hamsters, rats and rabbits. Toxicology 1978 0.95
17 Inhalation toxicity of acetaldehyde in rats. I. Acute and subacute studies. Toxicology 1982 0.93
18 Subacute (4-wk) oral toxicity of a combination of four nephrotoxins in rats: comparison with the toxicity of the individual compounds. Food Chem Toxicol 1993 0.92
19 Toxicity of mixtures of nephrotoxicants with similar or dissimilar mode of action. Food Chem Toxicol 1997 0.92
20 Letter: Dose-response correlation for the induction of respiratory-tract tumours in Syrian golden hamsters by intratracheal instillations of benzo(a)pyrene. Eur J Cancer 1973 0.91
21 Ultrastructure of pulmonary adenomas induced by intratracheal instillation of diethylnitrosamine in Syrian golden hamsters. Eur J Cancer 1973 0.90
22 Two-year drinking-water study of formaldehyde in rats. Food Chem Toxicol 1989 0.89
23 One-year time-sequence inhalation toxicity study of vinyl chloride in rats. II. Morphological changes in the respiratory tract, ceruminous glands, brain, kidneys, heart and spleen. Toxicology 1980 0.89
24 Safety evaluation of yeast grown on hydrocarbons. II. One-year feeding study in rats with yeast grown on pure n-paraffins. Food Cosmet Toxicol 1970 0.88
25 Use of factorial designs in combination toxicity studies. Food Chem Toxicol 1997 0.88
26 Safety evaluation of yeast grown on hydrocarbons. I. One-year feeding study in rats with yeast grown on gas oil. Food Cosmet Toxicol 1970 0.88
27 Chronic inhalation toxicity and carcinogenicity study of respirable polymeric methylene diphenyl diisocyanate (polymeric MDI) aerosol in rats. Fundam Appl Toxicol 1994 0.86
28 Statistically designed experiments in a tiered approach to screen mixtures of Fusarium mycotoxins for possible interactions. Food Chem Toxicol 2002 0.86
29 Acute (24 hr) toxicity of a combination of four nephrotoxicants in rats compared with the toxicity of the individual compounds. Food Chem Toxicol 1993 0.85
30 4-week oral toxicity study of a combination of eight chemicals in rats: comparison with the toxicity of the individual compounds. Food Chem Toxicol 1990 0.85
31 Carcinogenic response of the nasal cavity to inhaled chemical mixtures. Mutat Res 1997 0.85
32 Short-term toxicity studies on some salts and oxides of tin in rats. Food Cosmet Toxicol 1973 0.85
33 Lifespan oral toxicity study of vinyl chloride in rats. Food Cosmet Toxicol 1981 0.85
34 Inhalation toxicity of acetaldehyde in rats. IV. Progression and regression of nasal lesions after discontinuation of exposure. Toxicology 1987 0.84
35 Effects of alkali-treated proteins: feeding studies with free and protein-bound lysinoalanine in rats and other animals. J Nutr 1976 0.84
36 Chronic (89-week) feeding study with hydroxypropyl distarch phosphate, starch acetate, lactose and sodium alginate in mice. Food Chem Toxicol 1986 0.84
37 An evaluation of the criterion "organ weight" under conditions of growth retardation. Food Cosmet Toxicol 1973 0.84
38 Inhalation toxicity of acetaldehyde in rats. II. Carcinogenicity study: interim results after 15 months. Toxicology 1984 0.84
39 Subchronic (13-week) inhalation toxicity study of formaldehyde in rats. J Appl Toxicol 1987 0.84
40 Repeated exposure to acetaldehyde vapor. Studies in Syrian golden hamsters. Arch Environ Health 1975 0.83
41 Nutritional effects of alkali-treated soyprotein in rats. J Nutr 1974 0.83
42 Chronic inhalation toxicity and carcinogenicity study of methyl bromide in Wistar rats. Food Chem Toxicol 1991 0.82
43 Induction of hyperplasia in the bladder epithelium of rats by a dietary excess of acid or base: implications for toxicity/carcinogenicity testing. Food Chem Toxicol 1988 0.82
44 One-year inhalation toxicity study of formaldehyde in male rats with a damaged or undamaged nasal mucosa. J Appl Toxicol 1988 0.82
45 Comparative study of the ultrastructure of Tracheal and pulmonary tumours induced by multiple intratracheal instillations of diethylnitrosamine in Syrian golden hamsters. Eur J Cancer 1975 0.82
46 Effects of exposure to furfural vapour in hamsters simultaneously treated with benzo[alpha] pyrene or diethylnitrosamine. Toxicology 1978 0.82
47 Evaluation of the oral toxicity of acetaldehyde and formaldehyde in a 4-week drinking-water study in rats. Food Chem Toxicol 1988 0.82
48 The FEMA GRAS assessment of aliphatic and aromatic terpene hydrocarbons used as flavor ingredients. Food Chem Toxicol 2011 0.81
49 Lifetime (149-week) oral carcinogenicity study of vinyl chloride in rats. Food Chem Toxicol 1991 0.81
50 Safety assessment of lactate esters. Regul Toxicol Pharmacol 1998 0.81
51 Nature and histogenesis of sulfite-induced gastric lesions in rats. Exp Mol Pathol 1982 0.81
52 Gastric lesions in rats after the feeding of sulphite. Pathol Eur 1972 0.81
53 The toxicity of sulphite. I. Long-term feeding and multigeneration studies in rats. Food Cosmet Toxicol 1972 0.80
54 Chronic inhalation toxicity and carcinogenicity study of propylene oxide in Wistar rats. Food Chem Toxicol 1988 0.80
55 A critical appraisal of intratracheal instillation of benzo[a]pyrene to Syrian golden hamsters as a model in respiratory tract carcinogenesis. Cancer Lett 1995 0.80
56 Immunocytochemical identification of DNA adducts, O6-methylguanine and 7-methylguanine, in respiratory and other tissues of rat, mouse and Syrian hamster exposed to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Carcinogenesis 1994 0.80
57 Statistically designed experiments to screen chemical mixtures for possible interactions. Environ Health Perspect 1998 0.80
58 Safety evaluation of chemical mixtures and combinations of chemical and non-chemical stressors. Rev Environ Health 2004 0.79
59 One-year time sequence inhalation toxicity study of vinyl chloride in rats. I. Growth, mortality, haematology, clinical chemistry and organ weights. Toxicology 1979 0.79
60 Empirical approaches to risk estimation and prediction. IARC Sci Publ 1999 0.79
61 Effects of exposure to acetaldehyde in syrian hamsters simultaneously treated with benzo(a)pyrene or diethylnitrosamine. Prog Exp Tumor Res 1979 0.79
62 Effects of exposure to acrolein vapor in hamsters simultaneously treated with benzo[a]pyrene or diethylnitrosamine. J Toxicol Environ Health 1977 0.79
63 Significance of particle size of benzo(a)pyrene for the induction of respiratory tract tumours in hamsters. Int J Cancer 1980 0.79
64 Pathogenesis of blood-filled cavities in estrogen-induced anterior pituitary tumors in male Sprague-Dawley rats. Toxicol Pathol 1992 0.79
65 Toxicity of formaldehyde and acrolein mixtures: in vitro studies using nasal epithelial cells. Exp Toxicol Pathol 1996 0.78
66 Toxicology of sulphiting agents. I: Animal studies. Food Addit Contam 1993 0.78
67 An analysis of the possibility for health implications of joint actions and interactions between food additives. Regul Toxicol Pharmacol 2000 0.78
68 Vitamin A and beta-carotene influence the level of benzo[a]pyrene-induced DNA adducts and DNA-repair activities in hamster tracheal epithelium in organ culture. Cancer Lett 1995 0.78
69 Magnetic resonance imaging compared with hormonal effects and histopathology of estrogen-induced pituitary lesions in the rat. Carcinogenesis 1991 0.78
70 Effects of the exposure profile on the inhalation toxicity of carbon tetrachloride in male rats. J Appl Toxicol 1987 0.78
71 The FEMA GRAS assessment of hydroxy- and alkoxy-substituted benzyl derivatives used as flavor ingredients. Food Chem Toxicol 2005 0.78
72 Subchronic (13-week) inhalation toxicity study of formaldehyde in male rats: 8-hour intermittent versus 8-hour continuous exposures. Toxicol Lett 1989 0.77
73 Effects of a dietary load of acid or base on changes induced by lactose in rats. Food Chem Toxicol 1995 0.77
74 Sub-acute versus sub-chronic oral toxicity study in rats: comparative study of 82 compounds. J Appl Toxicol 1984 0.77
75 Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10. Xenobiotica 1996 0.77
76 Inhalation toxicity studies: OECD guidelines in relation to REACH and scientific developments. Exp Toxicol Pathol 2008 0.77
77 Subacute (4-week) inhalation toxicity study of formaldehyde in male rats: 8-hour intermittent versus 8-hour continuous exposures. J Appl Toxicol 1987 0.77
78 Cytotoxic and adaptive effects in rat nasal epithelium after 3-day and 13-week exposure to low concentrations of formaldehyde vapour. Toxicology 1988 0.77
79 The FEMA GRAS assessment of phenethyl alcohol, aldehyde, acid, and related acetals and esters used as flavor ingredients. Food Chem Toxicol 2005 0.77
80 Biochemical and histopathological changes in nasal epithelium of rats after 3-day intermittent exposure to formaldehyde and ozone alone or in combination. Toxicol Lett 1994 0.77
81 Repeated exposure to furfural vapour: 13-week study in Syrian golden hamsters. Zentralbl Bakteriol B 1979 0.77
82 Repeated exposure to alpha-ethylacrolein vapour: subacute toxicity study in rats. Toxicology 1981 0.77
83 Estimation of toxicity of chemical mixtures through modeling of chemical interactions. Environ Health Perspect 1998 0.77
84 Mucosal cysts in the gastrointestinal tract of beagle dogs. Lab Anim 1971 0.77
85 The FEMA GRAS assessment of benzyl derivatives used as flavor ingredients. Food Chem Toxicol 2005 0.77
86 Ultrastructure of hepatic angiosarcoma in rats induced by vinyl chloride. Exp Mol Pathol 1981 0.77
87 A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils. Food Chem Toxicol 2005 0.76
88 Complex mixtures: hazard identification and risk assessment. Food Chem Toxicol 1997 0.76
89 Spontaneous hyperplastic and metaplastic duct epithelium in the sublingual salivary glands of Wistar rats. Lab Anim 1986 0.76
90 Pulmonary response of hamsters to fibrous glass: chronic effects of repeated intratracheal instillation with or without benzo[a]pyrene. Carcinogenesis 1985 0.76
91 Acute, subacute, and subchronic inhalation toxicity studies of respirable polymeric methylene diphenyl diisocyanate (polymeric MDI) aerosol in rats. Fundam Appl Toxicol 1994 0.76
92 Glass fibers and vapor phase components of cigarette smoke as cofactors in experimental respiratory tract carcinogenesis. Carcinog Compr Surv 1985 0.76
93 Effect of variable versus fixed exposure levels on the toxicity of acetaldehyde in rats. J Appl Toxicol 1986 0.76
94 Rat pituitary changes observed with magnetic resonance imaging following removal of estrogen stimulus: correlation with histopathology and immunohistology. Carcinogenesis 1992 0.76
95 Lower respiratory tract tumours in Syrian golden hamsters after intratracheal instillations of diethylnitrosamine alone and with ferric oxide. Eur J Cancer 1972 0.76
96 The FEMA GRAS assessment of alpha,beta-unsaturated aldehydes and related substances used as flavor ingredients. Food Chem Toxicol 2008 0.76
97 An analysis of human response to the irritancy of acetone vapors. Crit Rev Toxicol 2002 0.76
98 Interactive effects of ozone and formaldehyde on the nasal respiratory lining epithelium in rats. J Toxicol Environ Health 1990 0.75
99 One-year time-sequence inhalation toxicity study of vinyl chloride in rats. III. Morphological changes in the liver. Toxicology 1980 0.75
100 Drinking water studies of formaldehyde in Sprague-Dawley rats. Toxicol Ind Health 1990 0.75
101 Chronic toxicity and oncogenicity inhalation study with vinyl acetate in the rat and mouse. Fundam Appl Toxicol 1994 0.75
102 Tissue damage and nutritional factors in experimental respiratory tract (Co-)carcinogenesis. Environ Health Perspect 1983 0.75
103 Bioassays for carcinogenicity in animals. Early preneoplastic lesions. IARC Sci Publ 1986 0.75
104 Naturally occurring endocardial disease in the rat. Arch Pathol 1973 0.75
105 Safety evaluation of synthetic beta-carotene. Crit Rev Toxicol 1999 0.75
106 Restoration of the rat nasal septum and turbinates after damage by intranasal electrocoagulation. Z Versuchstierkd 1988 0.75
107 Clearance of benzo(a)pyrene from the respiratory tract of hamsters following its intratracheal instillation with or without ferric oxide. Zentralbl Bakteriol Orig B 1976 0.75
108 Evaluation of potential neurotoxic effects of occupational exposure to (L)-lactates. Regul Toxicol Pharmacol 2001 0.75
109 Relation between benzo[a]pyrene-DNA adducts, cell proliferation and p53 expression in tracheal epithelium of hamsters fed a high beta-carotene diet. Carcinogenesis 1995 0.75
110 DNA adduct formation and repair in hamster and rat tracheas exposed to benzo[a]pyrene in organ culture. Carcinogenesis 1994 0.75
111 Repeated exposure to cyclopentenone vapour: long-term study in Syrian golden hamsters. Zentralbl Bakteriol Orig B 1976 0.75
112 Toxicity of beta-chloroprene (2-chlorobutadiene-1,3): acute and subacute toxicity. Toxicol Appl Pharmacol 1978 0.75
113 Gastric and caecal lesions in pigs following the feeding of sulphite. Tijdschr Diergeneeskd 1973 0.75
114 Short-term feeding study of thiodiethyleneglycol-bis-(beta-aminocrotonate) in rats. Food Cosmet Toxicol 1969 0.75
115 Repeated exposure to butenolide vapour: subacute study in Syrian golden hamsters. Toxicology 1979 0.75
116 Observations on the oral administration and toxicity of vinyl chloride in rats. Food Cosmet Toxicol 1975 0.75
117 Significance of the dog as 'second animal species' in toxicity testing for establishing the lowest 'no-toxic-effect level'. J Appl Toxicol 1986 0.75
118 Ciliated cells in vitamin A-deprived cultured hamster tracheal epithelium do divide. In Vitro Cell Dev Biol 1988 0.75
119 Testing of complex chemical mixtures (for carcinogenicity). IARC Sci Publ 1986 0.75
120 Basic requirements for long-term assays for carcinogenicity. IARC Monogr Eval Carcinog Risk Chem Hum Suppl 1980 0.75
121 Spontaneous tumors of the brain in rats. A report of 3 cases. Pathol Vet 1968 0.75
122 Letter: Rat feeding studies with alkali-treated soy protein. Nutr Rev 1974 0.75
123 The FEMA GRAS assessment of aromatic substituted secondary alcohols, ketones, and related esters used as flavor ingredients. Food Chem Toxicol 2006 0.75
124 Restoration of the hamster tracheal wall following injury by electrocoagulation. Exp Mol Pathol 1984 0.75
125 Safety evaluation of yeast grown on hydrocarbons. IV. Two-year feeding and multigeneration study in rats with yeast grown on pure n-paraffins. Food Cosmet Toxicol 1975 0.75
126 High survival rate of hamsters given intratracheal instillations of benzo[a]pyrene and ferric oxide and kept on a high beta-carotene diet. Carcinogenesis 1994 0.75
127 Safety evaluation of natural flavour complexes. Toxicol Lett 2004 0.75
128 Toxicologic studies of iocetamic acid in rats and dogs. Toxicol Appl Pharmacol 1969 0.75
129 Adenomatoid odontogenic tumorlike lesion in a male Wistar rat. J Oral Pathol Med 1992 0.75
130 Pancreatic atrophy and other pathological changes in rats following the feeding of stannous chloride. Pathol Eur 1974 0.75
131 Pulmonary response of hamsters to fibrous glass. Clearance and morphology after a single intratracheal instillation. Exp Pathol 1986 0.75
132 Cell proliferation and DNA adducts in hamster tracheal epithelium exposed to benzo[a]pyrene in organ culture. Toxicol In Vitro 1996 0.75
133 [Carcinogenicity studies in experimental animals. I. Design and performance]. Ned Tijdschr Geneeskd 1986 0.75
134 Safety evaluation of yeast grown on hydrocarbons. 3. Two-year feeding and multigeneration study in rats with yeast grown on gas oil. Food Cosmet Toxicol 1971 0.75
135 Toxicologic and pharmacologic properties of iocetamic acid, a new oral cholecystographic agent. Toxicol Appl Pharmacol 1969 0.75
136 Long-term assays for carcinogenicity in animals. IARC Sci Publ 1986 0.75
137 Electrocoagulation as a method to induce local lesions in the tracheal wall of Syrian hamsters. Z Versuchstierkd 1984 0.75
138 General toxicity testing: sense and non-sense, science and policy. Fundam Appl Toxicol 1984 0.75
139 Bioassays for carcinogenicity in animals. Assays for initiating and promoting activities. IARC Sci Publ 1986 0.75
140 The long-term study in rodents for identifying carcinogens: some controversies and suggestions for improvements. J Appl Toxicol 1986 0.75
141 [Carcinogenicity studies in experimental animals. II. Interpretation of the results and significance for man]. Ned Tijdschr Geneeskd 1986 0.75
142 Influence of growth factors and medium composition on benzo[a]pyrene- and vitamin A-induced cell proliferation and differentiation in hamster tracheal epithelium in organ culture. Toxicol In Vitro 1996 0.75
143 Respiratory tract tumors in hamsters after severe focal injury to the trachea and intratracheal instillation of benzo[a]pyrene. Cancer Lett 1985 0.75
144 Benzo[a]pyrene-induced respiratory tract cancer in hamsters fed a diet rich in beta-carotene. A histomorphological study. J Environ Pathol Toxicol Oncol 1995 0.75
145 Intranasal electrocoagulation in rats. Z Versuchstierkd 1987 0.75
146 Spontaneous squamous cell carcinoma of nasal and paranasal structures in the Cpb:WU (Wistar random) rat: nasolachrymal duct as major site of origin. J Environ Pathol Toxicol Oncol 1994 0.75
147 Multi-compartment model to study the effect of air-blood and blood-tissue partition coefficients on concentration-time-effect relationships. Arch Toxicol Suppl 1992 0.75
148 Ultrastructural changes in the kidneys of rabbits treated with lead acetate. Arch Toxicol 1981 0.75
149 Short-term inhalation toxicity studies with peroxyacetyl nitrate in rats. Toxicology 1977 0.75