Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Metabolic gene polymorphism frequencies in control populations.
|
Cancer Epidemiol Biomarkers Prev
|
2001
|
3.43
|
2
|
Benzo(a)pyrene diol epoxides as intermediates in nucleic acid binding in vitro and in vivo.
|
Science
|
1976
|
2.34
|
3
|
Environmental tobacco smoke and risk of respiratory cancer and chronic obstructive pulmonary disease in former smokers and never smokers in the EPIC prospective study.
|
BMJ
|
2005
|
2.22
|
4
|
Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals.
|
Environ Health Perspect
|
1999
|
2.03
|
5
|
Meta- and pooled analysis of GSTT1 and lung cancer: a HuGE-GSEC review.
|
Am J Epidemiol
|
2006
|
2.02
|
6
|
Structures of benzo(a)pyrene--nucleic acid adducts formed in human and bovine bronchial explants.
|
Nature
|
1977
|
1.68
|
7
|
High-frequency transfection and cytopathology of the hepatitis B virus core antigen gene in human cells.
|
Science
|
1983
|
1.67
|
8
|
DNA repair polymorphisms and cancer risk in non-smokers in a cohort study.
|
Carcinogenesis
|
2005
|
1.54
|
9
|
Explant culture of human colon.
|
Gastroenterology
|
1978
|
1.50
|
10
|
Cancer risk and occupational exposure to aflatoxins in Denmark.
|
Br J Cancer
|
1988
|
1.37
|
11
|
Clonal growth of epithelial cells from normal adult human bronchus.
|
Cancer Res
|
1981
|
1.33
|
12
|
Interindividual variation in binding of benzo[a]pyrene to DNA in cultured human bronchi.
|
Science
|
1976
|
1.32
|
13
|
Current smoking, occupation, N-acetyltransferase-2 and bladder cancer: a pooled analysis of genotype-based studies.
|
Cancer Epidemiol Biomarkers Prev
|
2001
|
1.14
|
14
|
Formaldehyde damage to DNA and inhibition of DNA repair in human bronchial cells.
|
Science
|
1983
|
1.10
|
15
|
Increased micronuclei and bulky DNA adducts in cord blood after maternal exposures to traffic-related air pollution.
|
Environ Res
|
2009
|
1.06
|
16
|
Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) polymorphisms in susceptibility to bladder cancer: the influence of smoking.
|
Cancer Epidemiol Biomarkers Prev
|
1997
|
1.05
|
17
|
Genetic susceptibility according to three metabolic pathways in cancers of the lung and bladder and in myeloid leukemias in nonsmokers.
|
Ann Oncol
|
2007
|
1.05
|
18
|
Biomarkers of genotoxicity of air pollution (the AULIS project): bulky DNA adducts in subjects with moderate to low exposures to airborne polycyclic aromatic hydrocarbons and their relationship to environmental tobacco smoke and other parameters.
|
Carcinogenesis
|
2001
|
1.04
|
19
|
Polymorphisms in NAT2, CYP2D6, CYP2C19 and GSTP1 and their association with prostate cancer.
|
Pharmacogenetics
|
1999
|
1.03
|
20
|
Metabolism of benzo(a)pyrene and 1-naphthol in cultured human tumorous and nontumorous colon.
|
Cancer Res
|
1983
|
1.03
|
21
|
Biological monitoring of foundry workers exposed to polycyclic aromatic hydrocarbons.
|
Br J Ind Med
|
1990
|
1.03
|
22
|
Human exposure to genotoxic carcinogens: methods and their limitations.
|
J Cancer Res Clin Oncol
|
1991
|
1.02
|
23
|
Endogenous nitrosation in relation to nitrate exposure from drinking water and diet in a Danish rural population.
|
Cancer Res
|
1989
|
1.01
|
24
|
Multi-factor dimensionality reduction applied to a large prospective investigation on gene-gene and gene-environment interactions.
|
Carcinogenesis
|
2006
|
1.01
|
25
|
Exposure of iron foundry workers to polycyclic aromatic hydrocarbons: benzo(a)pyrene-albumin adducts and 1-hydroxypyrene as biomarkers for exposure.
|
Occup Environ Med
|
1994
|
0.99
|
26
|
Explant culture of human colon.
|
Methods Cell Biol
|
1980
|
0.99
|
27
|
Detection of putative adduct with fluorescence characteristics identical to 2,3-dihydro-2-(7'-guanyl)-3-hydroxyaflatoxin B1 in human urine collected in Murang'a district, Kenya.
|
Carcinogenesis
|
1983
|
0.98
|
28
|
Determination of exposure to aflatoxins among Danish workers in animal-feed production through the analysis of aflatoxin B1 adducts to serum albumin.
|
Scand J Work Environ Health
|
1991
|
0.98
|
29
|
Genomic 5-methylcytosine determination by 32P-postlabeling analysis.
|
Anal Biochem
|
1986
|
0.95
|
30
|
Differences in metabolism of chemical carcinogens in cultured human epithelial tissues and cells.
|
J Cell Biochem
|
1982
|
0.94
|
31
|
Metabolism of benzo[a]pyrene by cultured tracheobronchial tissues from mice, rats, hamsters, bovines and humans.
|
Int J Cancer
|
1980
|
0.93
|
32
|
Aflatoxin exposure measured by urinary excretion of aflatoxin B1-guanine adduct and hepatitis B virus infection in areas with different liver cancer incidence in Kenya.
|
Cancer Res
|
1987
|
0.93
|
33
|
Biomarkers of genotoxicity of urban air pollution. Overview and descriptive data from a molecular epidemiology study on populations exposed to moderate-to-low levels of polycyclic aromatic hydrocarbons: the AULIS project.
|
Mutat Res
|
2001
|
0.92
|
34
|
Cigarette smoking, N-acetyltransferase 2 acetylation status, and bladder cancer risk: a case-series meta-analysis of a gene-environment interaction.
|
Cancer Epidemiol Biomarkers Prev
|
2000
|
0.92
|
35
|
Metabolism of [3H]benzo[a]pyrene by cultured human bronchus and cultured human pulmonary alveolar macrophages.
|
Lab Invest
|
1978
|
0.91
|
36
|
Explant culture of human peripheral lung. I. Metabolism of benzo[alpha]pyrene.
|
Lab Invest
|
1978
|
0.91
|
37
|
Glutathione S-transferases as risk factors in prostate cancer.
|
Eur J Cancer Prev
|
1999
|
0.90
|
38
|
Environmental air pollution and DNA adducts in Copenhagen bus drivers--effect of GSTM1 and NAT2 genotypes on adduct levels.
|
Carcinogenesis
|
1996
|
0.90
|
39
|
Human intestinal P-glycoprotein activity estimated by the model substrate digoxin.
|
Scand J Clin Lab Invest
|
2007
|
0.90
|
40
|
Long-term survival of normal adult human tissues as xenografts in congenitally athymic nude mice.
|
J Natl Cancer Inst
|
1981
|
0.89
|
41
|
Autoregulation of human CYP1A1 gene promotor activity in HepG2 and MCF-7 cells.
|
Carcinogenesis
|
1996
|
0.88
|
42
|
Metabolism of benzo(a)pyrene and identification of the major benzo(a)pyrene-DNA adducts in cultured human colon.
|
Cancer Res
|
1978
|
0.87
|
43
|
Induction of cytochrome P-450IA1, IA2, IIB1, IIB2 and IIE1 by broccoli in rat liver and colon.
|
Chem Biol Interact
|
1991
|
0.87
|
44
|
Transplacental exposure to tobacco smoke in human-adduct formation in placenta and umbilical cord blood vessels.
|
Teratog Carcinog Mutagen
|
1992
|
0.87
|
45
|
Metabolism of aflatoxin B1 and identification of the major aflatoxin B1-DNA adducts formed in cultured human bronchus and colon.
|
Cancer Res
|
1979
|
0.87
|
46
|
Detection of carcinogen-DNA adducts in human fetal tissues by the 32P-postlabeling procedure.
|
Environ Health Perspect
|
1993
|
0.87
|
47
|
Exposure of bus and taxi drivers to urban air pollutants as measured by DNA and protein adducts.
|
Toxicol Lett
|
1994
|
0.87
|
48
|
Effect of toxaphene on estrogen receptor functions in human breast cancer cells.
|
Carcinogenesis
|
1997
|
0.87
|
49
|
Impact of phase I or phase II enzyme polymorphisms on lymphocyte DNA adducts in subjects exposed to urban air pollution and environmental tobacco smoke.
|
Toxicol Lett
|
2004
|
0.86
|
50
|
Metabolism of benzo(a)pyrene, N-nitrosodimethylamine, and N-nitrosopyrrolidine and identification of the major carcinogen-DNA adducts formed in cultured human esophagus.
|
Cancer Res
|
1979
|
0.86
|
51
|
Human bronchus-mediated mutagenesis of mammalian cells by carcinogenic polynuclear aromatic hydrocarbons.
|
Proc Natl Acad Sci U S A
|
1978
|
0.86
|
52
|
Monitoring human exposure to 2-hydroxyethylating carcinogens.
|
Environ Health Perspect
|
1996
|
0.86
|
53
|
Biomonitoring of diesel exhaust-exposed workers. DNA and hemoglobin adducts and urinary 1-hydroxypyrene as markers of exposure.
|
Toxicol Lett
|
1996
|
0.85
|
54
|
Methodology of laboratory measurements in prospective studies on gene-environment interactions: the experience of GenAir.
|
Mutat Res
|
2005
|
0.85
|
55
|
Explant culture of rat colon: a model system for studying metabolism of chemical carcinogens.
|
In Vitro
|
1978
|
0.85
|
56
|
Activation of chemical carcinogens by cultured human fetal liver, esophagus and stomach.
|
Chem Biol Interact
|
1984
|
0.84
|
57
|
Future research needs associated with the assessment of potential human health risks from exposure to toxic ambient air pollutants.
|
Environ Health Perspect
|
1994
|
0.84
|
58
|
Exposure to urban and rural air pollution: DNA and protein adducts and effect of glutathione-S-transferase genotype on adduct levels.
|
Int Arch Occup Environ Health
|
1996
|
0.83
|
59
|
Metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in cultured human bronchus and pancreatic duct.
|
Cancer Res
|
1977
|
0.83
|
60
|
Repair of DNA lesions induced by ultraviolet irradiation and aromatic amines in normal and repair-deficient human lymphoblastoid cell lines.
|
Carcinogenesis
|
1995
|
0.83
|
61
|
Induction of cytochrome P450IA1 in rat colon and liver by indole-3-carbinol and 5,6-benzoflavone.
|
Carcinogenesis
|
1990
|
0.82
|
62
|
Metabolism of acyclic and cyclic N-nitrosamines in cultured human bronchi.
|
J Natl Cancer Inst
|
1977
|
0.82
|
63
|
Exposure to aflatoxin B1 in animal-feed production plant workers.
|
Environ Health Perspect
|
1993
|
0.81
|
64
|
Long-term organ culture of adult rat colon.
|
Pathol Res Pract
|
1978
|
0.81
|
65
|
Comparison of benzo(a)pyrene metabolism in bronchus, esophagus, colon, and duodenum from the same individual.
|
Cancer Res
|
1982
|
0.81
|
66
|
Metabolism of 1,2-dimethylhydrazine by cultured human colon.
|
Carcinogenesis
|
1980
|
0.81
|
67
|
Excretion of benzo[a]pyrene-Gua adduct in the urine of benzo[a]pyrene-treated rats.
|
Chem Biol Interact
|
1986
|
0.81
|
68
|
Induction of cytochrome P-450IA1 gene expression in human breast tumour cell lines.
|
Chem Biol Interact
|
1988
|
0.81
|
69
|
Nitrate exposure from drinking water and diet in a Danish rural population.
|
Int J Epidemiol
|
1989
|
0.81
|
70
|
Metabolism of acyclic and cyclic N-nitrosamines by cultured human colon.
|
Proc Soc Exp Biol Med
|
1978
|
0.80
|
71
|
Differences in 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible CYP1A1 expression in human breast carcinoma cell lines involve altered trans-acting factors.
|
Eur J Biochem
|
1991
|
0.80
|
72
|
Metabolic activation of benzo(a)pyrene and binding to DNA in cultured human bronchus.
|
Cancer Res
|
1977
|
0.80
|
73
|
Metabolism of chemical carcinogens by cultured human and rat bladder epithelial cells.
|
Carcinogenesis
|
1981
|
0.80
|
74
|
BIOMarkers for occupational diesel exhaust exposure monitoring (BIOMODEM)--a study in underground mining.
|
Toxicol Lett
|
2002
|
0.80
|
75
|
Substances with affinity to a monoclonal aflatoxin B1 antibody in Danish urine samples.
|
Food Chem Toxicol
|
1988
|
0.80
|
76
|
Inter-individual variations in carcinogen metabolism.
|
Arch Toxicol Suppl
|
1986
|
0.79
|
77
|
Separation of water-soluble metabolites of benzo[a]pyrene formed by cultured human colon.
|
Biochem Pharmacol
|
1979
|
0.79
|
78
|
Genotoxic damage in mine workers exposed to diesel exhaust, and the effects of glutathione transferase genotypes.
|
Mutat Res
|
2005
|
0.79
|
79
|
Metabolism of benzo[a]pyrene by cultured rat and human buccal mucosa cells.
|
Carcinogenesis
|
1985
|
0.79
|
80
|
Abstracts of the 6th FECS Conference 1998 Lectures.
|
Environ Sci Pollut Res Int
|
1998
|
0.79
|
81
|
The effects of the continuous administration of N,N-dimethyl-4-phenylazoaniline (DAB) on the activities and the inducibilities of some drug-metabolizing enzymes in rat liver.
|
Chem Biol Interact
|
1975
|
0.79
|
82
|
Uptake of benzo[a]pyrene--ferric oxide particulates by human pulmonary macrophages and release of benzo[a]pyrene and its metabolites.
|
Proc Soc Exp Biol Med
|
1979
|
0.78
|
83
|
Carcinogen metabolism in human tissues and cells.
|
Drug Metab Rev
|
1982
|
0.78
|
84
|
Inhibition of intercellular communication by condensates of high and low tar cigarettes.
|
Arch Toxicol
|
1995
|
0.78
|
85
|
Effect of a negative regulatory element (NRE) on the human CYP1A1 gene expression in breast carcinoma MCF-7 and hepatoma HepG2 cells.
|
FEBS Lett
|
1995
|
0.78
|
86
|
Biomonitoring human exposure to environmental carcinogenic chemicals.
|
Mutagenesis
|
1996
|
0.78
|
87
|
Metabolism of aflatoxin B1, benzo[a]pyrene, and 1,2-dimethylhydrazine by cultured rat and human colon.
|
Teratog Carcinog Mutagen
|
1980
|
0.78
|
88
|
Extracts of airborne particulates collected at different locations in the Copenhagen area induce the expression of cytochrome P-450IA1.
|
J Toxicol Environ Health
|
1990
|
0.78
|
89
|
Metabolism of N-nitrosamines by cultured human and rat esophagus.
|
Cancer Res
|
1982
|
0.77
|
90
|
Chromosomal aberrations in humans induced by urban air pollution: influence of DNA repair and polymorphisms of glutathione S-transferase M1 and N-acetyltransferase 2.
|
Cancer Epidemiol Biomarkers Prev
|
1999
|
0.77
|
91
|
Thresholds in genetic toxicology - concluding remarks.
|
Mutat Res
|
2000
|
0.77
|
92
|
Detection of tobacco smoke carcinogen-DNA adducts in cultured rat buccal mucosa cells following exposure to ethanol and total cigarette smoke condensate or chewing tobacco.
|
Chem Biol Interact
|
1992
|
0.77
|
93
|
Glutathione S-transferase mu as a risk factor in bladder tumours.
|
Pharmacogenetics
|
1996
|
0.77
|
94
|
Biochemical and molecular epidemiology of human cancer risk.
|
Monogr Pathol
|
1985
|
0.77
|
95
|
Risk assessment: the importance of genetic polymorphisms in man.
|
Mutat Res
|
2001
|
0.76
|
96
|
Methylated DNA adducts in the large intestine of ICR/Ha and C57BL/Ha mice given 1,2-dimethylhydrazine.
|
J Natl Cancer Inst
|
1983
|
0.76
|
97
|
The skin tumor-promoter 12-O-tetradecanoylphorbol-13-acetate induces transcription of the c-fos proto-oncogene in human bladder epithelial cells.
|
Carcinogenesis
|
1986
|
0.76
|
98
|
Comparative synchronous fluorescence spectrophotometry and 32P-postlabeling analysis of PAH-DNA adducts in human lung and the relationship to TP53 mutations.
|
Mutat Res
|
1996
|
0.76
|
99
|
Prostaglandin H synthase-dependent co-oxygenation of (+/-)-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene in hamster trachea and human bronchus explants.
|
Carcinogenesis
|
1984
|
0.76
|
100
|
Sucrose, glucose and fructose have similar genotoxicity in the rat colon and affect the metabolome.
|
Food Chem Toxicol
|
2007
|
0.75
|
101
|
Urinary 1-hydroxypyrene, a PAH biomarker in foundry workers.
|
Cancer Detect Prev
|
1996
|
0.75
|
102
|
Detection of 8,9-dihydro-(7'-guanyl)-9-hydroxyaflatoxin B1 in human urine.
|
Environ Health Perspect
|
1985
|
0.75
|
103
|
Interindividual variation in carcinogen metabolism, DNA damage and DNA repair.
|
IARC Sci Publ
|
1984
|
0.75
|
104
|
Urinary excretion of N-nitrosoproline in relation to consumption of raw and cooked vegetables in a Danish rural population.
|
IARC Sci Publ
|
1991
|
0.75
|
105
|
Deregulation in trans or c-myc expression in immortalized human urothelial cells and in T24 bladder carcinoma cells.
|
Mol Carcinog
|
1990
|
0.75
|
106
|
Cytochrome P450-mediated metabolism of tumour promoters modifies the inhibition of intercellular communication: a modified assay for tumour promotion.
|
Carcinogenesis
|
1993
|
0.75
|
107
|
Two phorbol ester receptor affinities in partially transformed human urothelial cells and decrease of receptor binding in desensitized cells.
|
Experientia
|
1993
|
0.75
|
108
|
Metabolism of chemical carcinogens by tracheobronchial tissues.
|
Basic Life Sci
|
1983
|
0.75
|
109
|
Detection of metabolites of N-nitrosopyrrolidine and N-nitrosoethylmethylamine in cultures of human bladder epithelial cells of normal origin.
|
IARC Sci Publ
|
1982
|
0.75
|
110
|
[Lead-free gasoline].
|
Ugeskr Laeger
|
1998
|
0.75
|
111
|
Analysis of native human plasma proteins and haemoglobin for the presence of bityrosine by high-performance liquid chromatography.
|
Pharmacol Toxicol
|
1997
|
0.75
|
112
|
A strong genotoxic effect in mouse skin of a single painting of coal tar in hairless mice and in MutaMouse.
|
Mutat Res
|
2000
|
0.75
|
113
|
Metabolism of tobacco specific carcinogens in cultured rat buccal mucosa epithelial cells.
|
Acta Pharmacol Toxicol (Copenh)
|
1986
|
0.75
|
114
|
DNA and protein adducts.
|
Toxicology
|
1995
|
0.75
|
115
|
Microsomal drug-metabolizing enzymes in the olive baboon (Papio anabis).
|
Comp Biochem Physiol B
|
1975
|
0.75
|
116
|
Malignant transformation of human bladder epithelial cells by DNA transfection with the v-raf oncogene.
|
Mol Carcinog
|
1989
|
0.75
|
117
|
Metabolism of dimethylnitrosamine and 1,2-dimethylhydrazine in cultured human bronchi.
|
Cancer Res
|
1977
|
0.75
|
118
|
Studies of host factors in carcinogenesis using cultured human tissues and cells.
|
IARC Sci Publ
|
1982
|
0.75
|
119
|
Effect of various chemicals on the metabolism of benzo(a)pyrene by cultured rat colon.
|
Chem Biol Interact
|
1977
|
0.75
|
120
|
Some characteristics of two azoreductase systems in rat liver. Relevance to the activity of 2-[4'-di(2"-bromopropyl)-aminophenylazo]benzoic acid (CB10-252), a compound possessing latent cytotoxic activity.
|
Chem Biol Interact
|
1975
|
0.75
|
121
|
Differential induction of transcription of c-myc and c-fos proto-oncogenes by 12-O-tetradecanoylphorbol-13-acetate in mortal and immortal human urothelial cells.
|
J Cell Biochem
|
1987
|
0.75
|
122
|
Report from the working group on cancer and the non-occupational environment.
|
Pharmacol Toxicol
|
1993
|
0.75
|
123
|
[Excretion of aflatoxin in dockers with occupational exposure].
|
Ugeskr Laeger
|
1985
|
0.75
|
124
|
Activation by reductive cleavage of potentially cytotoxic azo compounds by human hepatocellular carcinoma.
|
Biochem Pharmacol
|
1974
|
0.75
|
125
|
Sulphoxidation of S-carboxymethyl-L-cysteine in the rhesus monkey (Macaca mulatta), cynomologus monkey (Macaca fascicularis), African green monkey (Cercopithecus aethiops) and the marmoset (Callithrix jacchus).
|
Comp Biochem Physiol B
|
1986
|
0.75
|
126
|
Glutathione S-transferase genotype and p53 mutations in adenocarcinoma of the small intestine.
|
Scand J Gastroenterol
|
2003
|
0.75
|