H Autrup

Author PubWeight™ 99.69‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiol Biomarkers Prev 2001 3.43
2 Benzo(a)pyrene diol epoxides as intermediates in nucleic acid binding in vitro and in vivo. Science 1976 2.34
3 Environmental tobacco smoke and risk of respiratory cancer and chronic obstructive pulmonary disease in former smokers and never smokers in the EPIC prospective study. BMJ 2005 2.22
4 Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals. Environ Health Perspect 1999 2.03
5 Meta- and pooled analysis of GSTT1 and lung cancer: a HuGE-GSEC review. Am J Epidemiol 2006 2.02
6 Structures of benzo(a)pyrene--nucleic acid adducts formed in human and bovine bronchial explants. Nature 1977 1.68
7 High-frequency transfection and cytopathology of the hepatitis B virus core antigen gene in human cells. Science 1983 1.67
8 DNA repair polymorphisms and cancer risk in non-smokers in a cohort study. Carcinogenesis 2005 1.54
9 Explant culture of human colon. Gastroenterology 1978 1.50
10 Cancer risk and occupational exposure to aflatoxins in Denmark. Br J Cancer 1988 1.37
11 Clonal growth of epithelial cells from normal adult human bronchus. Cancer Res 1981 1.33
12 Interindividual variation in binding of benzo[a]pyrene to DNA in cultured human bronchi. Science 1976 1.32
13 Current smoking, occupation, N-acetyltransferase-2 and bladder cancer: a pooled analysis of genotype-based studies. Cancer Epidemiol Biomarkers Prev 2001 1.14
14 Formaldehyde damage to DNA and inhibition of DNA repair in human bronchial cells. Science 1983 1.10
15 Increased micronuclei and bulky DNA adducts in cord blood after maternal exposures to traffic-related air pollution. Environ Res 2009 1.06
16 Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) polymorphisms in susceptibility to bladder cancer: the influence of smoking. Cancer Epidemiol Biomarkers Prev 1997 1.05
17 Genetic susceptibility according to three metabolic pathways in cancers of the lung and bladder and in myeloid leukemias in nonsmokers. Ann Oncol 2007 1.05
18 Biomarkers of genotoxicity of air pollution (the AULIS project): bulky DNA adducts in subjects with moderate to low exposures to airborne polycyclic aromatic hydrocarbons and their relationship to environmental tobacco smoke and other parameters. Carcinogenesis 2001 1.04
19 Polymorphisms in NAT2, CYP2D6, CYP2C19 and GSTP1 and their association with prostate cancer. Pharmacogenetics 1999 1.03
20 Metabolism of benzo(a)pyrene and 1-naphthol in cultured human tumorous and nontumorous colon. Cancer Res 1983 1.03
21 Biological monitoring of foundry workers exposed to polycyclic aromatic hydrocarbons. Br J Ind Med 1990 1.03
22 Human exposure to genotoxic carcinogens: methods and their limitations. J Cancer Res Clin Oncol 1991 1.02
23 Endogenous nitrosation in relation to nitrate exposure from drinking water and diet in a Danish rural population. Cancer Res 1989 1.01
24 Multi-factor dimensionality reduction applied to a large prospective investigation on gene-gene and gene-environment interactions. Carcinogenesis 2006 1.01
25 Exposure of iron foundry workers to polycyclic aromatic hydrocarbons: benzo(a)pyrene-albumin adducts and 1-hydroxypyrene as biomarkers for exposure. Occup Environ Med 1994 0.99
26 Explant culture of human colon. Methods Cell Biol 1980 0.99
27 Detection of putative adduct with fluorescence characteristics identical to 2,3-dihydro-2-(7'-guanyl)-3-hydroxyaflatoxin B1 in human urine collected in Murang'a district, Kenya. Carcinogenesis 1983 0.98
28 Determination of exposure to aflatoxins among Danish workers in animal-feed production through the analysis of aflatoxin B1 adducts to serum albumin. Scand J Work Environ Health 1991 0.98
29 Genomic 5-methylcytosine determination by 32P-postlabeling analysis. Anal Biochem 1986 0.95
30 Differences in metabolism of chemical carcinogens in cultured human epithelial tissues and cells. J Cell Biochem 1982 0.94
31 Metabolism of benzo[a]pyrene by cultured tracheobronchial tissues from mice, rats, hamsters, bovines and humans. Int J Cancer 1980 0.93
32 Aflatoxin exposure measured by urinary excretion of aflatoxin B1-guanine adduct and hepatitis B virus infection in areas with different liver cancer incidence in Kenya. Cancer Res 1987 0.93
33 Biomarkers of genotoxicity of urban air pollution. Overview and descriptive data from a molecular epidemiology study on populations exposed to moderate-to-low levels of polycyclic aromatic hydrocarbons: the AULIS project. Mutat Res 2001 0.92
34 Cigarette smoking, N-acetyltransferase 2 acetylation status, and bladder cancer risk: a case-series meta-analysis of a gene-environment interaction. Cancer Epidemiol Biomarkers Prev 2000 0.92
35 Metabolism of [3H]benzo[a]pyrene by cultured human bronchus and cultured human pulmonary alveolar macrophages. Lab Invest 1978 0.91
36 Explant culture of human peripheral lung. I. Metabolism of benzo[alpha]pyrene. Lab Invest 1978 0.91
37 Glutathione S-transferases as risk factors in prostate cancer. Eur J Cancer Prev 1999 0.90
38 Environmental air pollution and DNA adducts in Copenhagen bus drivers--effect of GSTM1 and NAT2 genotypes on adduct levels. Carcinogenesis 1996 0.90
39 Human intestinal P-glycoprotein activity estimated by the model substrate digoxin. Scand J Clin Lab Invest 2007 0.90
40 Long-term survival of normal adult human tissues as xenografts in congenitally athymic nude mice. J Natl Cancer Inst 1981 0.89
41 Autoregulation of human CYP1A1 gene promotor activity in HepG2 and MCF-7 cells. Carcinogenesis 1996 0.88
42 Metabolism of benzo(a)pyrene and identification of the major benzo(a)pyrene-DNA adducts in cultured human colon. Cancer Res 1978 0.87
43 Induction of cytochrome P-450IA1, IA2, IIB1, IIB2 and IIE1 by broccoli in rat liver and colon. Chem Biol Interact 1991 0.87
44 Transplacental exposure to tobacco smoke in human-adduct formation in placenta and umbilical cord blood vessels. Teratog Carcinog Mutagen 1992 0.87
45 Metabolism of aflatoxin B1 and identification of the major aflatoxin B1-DNA adducts formed in cultured human bronchus and colon. Cancer Res 1979 0.87
46 Detection of carcinogen-DNA adducts in human fetal tissues by the 32P-postlabeling procedure. Environ Health Perspect 1993 0.87
47 Exposure of bus and taxi drivers to urban air pollutants as measured by DNA and protein adducts. Toxicol Lett 1994 0.87
48 Effect of toxaphene on estrogen receptor functions in human breast cancer cells. Carcinogenesis 1997 0.87
49 Impact of phase I or phase II enzyme polymorphisms on lymphocyte DNA adducts in subjects exposed to urban air pollution and environmental tobacco smoke. Toxicol Lett 2004 0.86
50 Metabolism of benzo(a)pyrene, N-nitrosodimethylamine, and N-nitrosopyrrolidine and identification of the major carcinogen-DNA adducts formed in cultured human esophagus. Cancer Res 1979 0.86
51 Human bronchus-mediated mutagenesis of mammalian cells by carcinogenic polynuclear aromatic hydrocarbons. Proc Natl Acad Sci U S A 1978 0.86
52 Monitoring human exposure to 2-hydroxyethylating carcinogens. Environ Health Perspect 1996 0.86
53 Biomonitoring of diesel exhaust-exposed workers. DNA and hemoglobin adducts and urinary 1-hydroxypyrene as markers of exposure. Toxicol Lett 1996 0.85
54 Methodology of laboratory measurements in prospective studies on gene-environment interactions: the experience of GenAir. Mutat Res 2005 0.85
55 Explant culture of rat colon: a model system for studying metabolism of chemical carcinogens. In Vitro 1978 0.85
56 Activation of chemical carcinogens by cultured human fetal liver, esophagus and stomach. Chem Biol Interact 1984 0.84
57 Future research needs associated with the assessment of potential human health risks from exposure to toxic ambient air pollutants. Environ Health Perspect 1994 0.84
58 Exposure to urban and rural air pollution: DNA and protein adducts and effect of glutathione-S-transferase genotype on adduct levels. Int Arch Occup Environ Health 1996 0.83
59 Metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in cultured human bronchus and pancreatic duct. Cancer Res 1977 0.83
60 Repair of DNA lesions induced by ultraviolet irradiation and aromatic amines in normal and repair-deficient human lymphoblastoid cell lines. Carcinogenesis 1995 0.83
61 Induction of cytochrome P450IA1 in rat colon and liver by indole-3-carbinol and 5,6-benzoflavone. Carcinogenesis 1990 0.82
62 Metabolism of acyclic and cyclic N-nitrosamines in cultured human bronchi. J Natl Cancer Inst 1977 0.82
63 Exposure to aflatoxin B1 in animal-feed production plant workers. Environ Health Perspect 1993 0.81
64 Long-term organ culture of adult rat colon. Pathol Res Pract 1978 0.81
65 Comparison of benzo(a)pyrene metabolism in bronchus, esophagus, colon, and duodenum from the same individual. Cancer Res 1982 0.81
66 Metabolism of 1,2-dimethylhydrazine by cultured human colon. Carcinogenesis 1980 0.81
67 Excretion of benzo[a]pyrene-Gua adduct in the urine of benzo[a]pyrene-treated rats. Chem Biol Interact 1986 0.81
68 Induction of cytochrome P-450IA1 gene expression in human breast tumour cell lines. Chem Biol Interact 1988 0.81
69 Nitrate exposure from drinking water and diet in a Danish rural population. Int J Epidemiol 1989 0.81
70 Metabolism of acyclic and cyclic N-nitrosamines by cultured human colon. Proc Soc Exp Biol Med 1978 0.80
71 Differences in 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible CYP1A1 expression in human breast carcinoma cell lines involve altered trans-acting factors. Eur J Biochem 1991 0.80
72 Metabolic activation of benzo(a)pyrene and binding to DNA in cultured human bronchus. Cancer Res 1977 0.80
73 Metabolism of chemical carcinogens by cultured human and rat bladder epithelial cells. Carcinogenesis 1981 0.80
74 BIOMarkers for occupational diesel exhaust exposure monitoring (BIOMODEM)--a study in underground mining. Toxicol Lett 2002 0.80
75 Substances with affinity to a monoclonal aflatoxin B1 antibody in Danish urine samples. Food Chem Toxicol 1988 0.80
76 Inter-individual variations in carcinogen metabolism. Arch Toxicol Suppl 1986 0.79
77 Separation of water-soluble metabolites of benzo[a]pyrene formed by cultured human colon. Biochem Pharmacol 1979 0.79
78 Genotoxic damage in mine workers exposed to diesel exhaust, and the effects of glutathione transferase genotypes. Mutat Res 2005 0.79
79 Metabolism of benzo[a]pyrene by cultured rat and human buccal mucosa cells. Carcinogenesis 1985 0.79
80 Abstracts of the 6th FECS Conference 1998 Lectures. Environ Sci Pollut Res Int 1998 0.79
81 The effects of the continuous administration of N,N-dimethyl-4-phenylazoaniline (DAB) on the activities and the inducibilities of some drug-metabolizing enzymes in rat liver. Chem Biol Interact 1975 0.79
82 Uptake of benzo[a]pyrene--ferric oxide particulates by human pulmonary macrophages and release of benzo[a]pyrene and its metabolites. Proc Soc Exp Biol Med 1979 0.78
83 Carcinogen metabolism in human tissues and cells. Drug Metab Rev 1982 0.78
84 Inhibition of intercellular communication by condensates of high and low tar cigarettes. Arch Toxicol 1995 0.78
85 Effect of a negative regulatory element (NRE) on the human CYP1A1 gene expression in breast carcinoma MCF-7 and hepatoma HepG2 cells. FEBS Lett 1995 0.78
86 Biomonitoring human exposure to environmental carcinogenic chemicals. Mutagenesis 1996 0.78
87 Metabolism of aflatoxin B1, benzo[a]pyrene, and 1,2-dimethylhydrazine by cultured rat and human colon. Teratog Carcinog Mutagen 1980 0.78
88 Extracts of airborne particulates collected at different locations in the Copenhagen area induce the expression of cytochrome P-450IA1. J Toxicol Environ Health 1990 0.78
89 Metabolism of N-nitrosamines by cultured human and rat esophagus. Cancer Res 1982 0.77
90 Chromosomal aberrations in humans induced by urban air pollution: influence of DNA repair and polymorphisms of glutathione S-transferase M1 and N-acetyltransferase 2. Cancer Epidemiol Biomarkers Prev 1999 0.77
91 Thresholds in genetic toxicology - concluding remarks. Mutat Res 2000 0.77
92 Detection of tobacco smoke carcinogen-DNA adducts in cultured rat buccal mucosa cells following exposure to ethanol and total cigarette smoke condensate or chewing tobacco. Chem Biol Interact 1992 0.77
93 Glutathione S-transferase mu as a risk factor in bladder tumours. Pharmacogenetics 1996 0.77
94 Biochemical and molecular epidemiology of human cancer risk. Monogr Pathol 1985 0.77
95 Risk assessment: the importance of genetic polymorphisms in man. Mutat Res 2001 0.76
96 Methylated DNA adducts in the large intestine of ICR/Ha and C57BL/Ha mice given 1,2-dimethylhydrazine. J Natl Cancer Inst 1983 0.76
97 The skin tumor-promoter 12-O-tetradecanoylphorbol-13-acetate induces transcription of the c-fos proto-oncogene in human bladder epithelial cells. Carcinogenesis 1986 0.76
98 Comparative synchronous fluorescence spectrophotometry and 32P-postlabeling analysis of PAH-DNA adducts in human lung and the relationship to TP53 mutations. Mutat Res 1996 0.76
99 Prostaglandin H synthase-dependent co-oxygenation of (+/-)-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene in hamster trachea and human bronchus explants. Carcinogenesis 1984 0.76
100 Sucrose, glucose and fructose have similar genotoxicity in the rat colon and affect the metabolome. Food Chem Toxicol 2007 0.75
101 Urinary 1-hydroxypyrene, a PAH biomarker in foundry workers. Cancer Detect Prev 1996 0.75
102 Detection of 8,9-dihydro-(7'-guanyl)-9-hydroxyaflatoxin B1 in human urine. Environ Health Perspect 1985 0.75
103 Interindividual variation in carcinogen metabolism, DNA damage and DNA repair. IARC Sci Publ 1984 0.75
104 Urinary excretion of N-nitrosoproline in relation to consumption of raw and cooked vegetables in a Danish rural population. IARC Sci Publ 1991 0.75
105 Deregulation in trans or c-myc expression in immortalized human urothelial cells and in T24 bladder carcinoma cells. Mol Carcinog 1990 0.75
106 Cytochrome P450-mediated metabolism of tumour promoters modifies the inhibition of intercellular communication: a modified assay for tumour promotion. Carcinogenesis 1993 0.75
107 Two phorbol ester receptor affinities in partially transformed human urothelial cells and decrease of receptor binding in desensitized cells. Experientia 1993 0.75
108 Metabolism of chemical carcinogens by tracheobronchial tissues. Basic Life Sci 1983 0.75
109 Detection of metabolites of N-nitrosopyrrolidine and N-nitrosoethylmethylamine in cultures of human bladder epithelial cells of normal origin. IARC Sci Publ 1982 0.75
110 [Lead-free gasoline]. Ugeskr Laeger 1998 0.75
111 Analysis of native human plasma proteins and haemoglobin for the presence of bityrosine by high-performance liquid chromatography. Pharmacol Toxicol 1997 0.75
112 A strong genotoxic effect in mouse skin of a single painting of coal tar in hairless mice and in MutaMouse. Mutat Res 2000 0.75
113 Metabolism of tobacco specific carcinogens in cultured rat buccal mucosa epithelial cells. Acta Pharmacol Toxicol (Copenh) 1986 0.75
114 DNA and protein adducts. Toxicology 1995 0.75
115 Microsomal drug-metabolizing enzymes in the olive baboon (Papio anabis). Comp Biochem Physiol B 1975 0.75
116 Malignant transformation of human bladder epithelial cells by DNA transfection with the v-raf oncogene. Mol Carcinog 1989 0.75
117 Metabolism of dimethylnitrosamine and 1,2-dimethylhydrazine in cultured human bronchi. Cancer Res 1977 0.75
118 Studies of host factors in carcinogenesis using cultured human tissues and cells. IARC Sci Publ 1982 0.75
119 Effect of various chemicals on the metabolism of benzo(a)pyrene by cultured rat colon. Chem Biol Interact 1977 0.75
120 Some characteristics of two azoreductase systems in rat liver. Relevance to the activity of 2-[4'-di(2"-bromopropyl)-aminophenylazo]benzoic acid (CB10-252), a compound possessing latent cytotoxic activity. Chem Biol Interact 1975 0.75
121 Differential induction of transcription of c-myc and c-fos proto-oncogenes by 12-O-tetradecanoylphorbol-13-acetate in mortal and immortal human urothelial cells. J Cell Biochem 1987 0.75
122 Report from the working group on cancer and the non-occupational environment. Pharmacol Toxicol 1993 0.75
123 [Excretion of aflatoxin in dockers with occupational exposure]. Ugeskr Laeger 1985 0.75
124 Activation by reductive cleavage of potentially cytotoxic azo compounds by human hepatocellular carcinoma. Biochem Pharmacol 1974 0.75
125 Sulphoxidation of S-carboxymethyl-L-cysteine in the rhesus monkey (Macaca mulatta), cynomologus monkey (Macaca fascicularis), African green monkey (Cercopithecus aethiops) and the marmoset (Callithrix jacchus). Comp Biochem Physiol B 1986 0.75
126 Glutathione S-transferase genotype and p53 mutations in adenocarcinoma of the small intestine. Scand J Gastroenterol 2003 0.75