Published in Proc Soc Exp Biol Med on October 01, 1978
Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk. Int J Cancer (2011) 0.97
Microbial and metabolic profile of achlorhydric stomach: comparison of pernicious anaemia and hypogammaglobulinaemia. J Clin Pathol (1985) 0.84
p53 mutations in human cancers. Science (1991) 31.96
Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res (1994) 11.29
Mutational hotspot in the p53 gene in human hepatocellular carcinomas. Nature (1991) 6.16
Database of p53 gene somatic mutations in human tumors and cell lines. Nucleic Acids Res (1994) 5.64
Histologic fixatives suitable for diagnostic light and electron microscopy. Arch Pathol Lab Med (1976) 5.37
Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells. Mol Cell (1999) 5.28
Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3. Proc Natl Acad Sci U S A (1994) 3.76
SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity. Nat Genet (2001) 3.76
IARC Database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation tools. Nucleic Acids Res (1998) 3.74
The nomenclature of cell death: recommendations of an ad hoc Committee of the Society of Toxicologic Pathologists. Toxicol Pathol (1999) 3.73
Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiol Biomarkers Prev (2001) 3.43
Studies on cellular autophagocytosis. The formation of autophagic vacuoles in the liver after glucagon administration. Am J Pathol (1968) 3.13
Type beta transforming growth factor is the primary differentiation-inducing serum factor for normal human bronchial epithelial cells. Proc Natl Acad Sci U S A (1986) 2.93
Distribution and modulation of the cellular receptor for transforming growth factor-beta. J Cell Biol (1987) 2.87
Environmental tobacco smoke, genetic susceptibility, and risk of lung cancer in never-smoking women. J Natl Cancer Inst (1999) 2.83
Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis. Nat Genet (2001) 2.82
GADD45 induction of a G2/M cell cycle checkpoint. Proc Natl Acad Sci U S A (1999) 2.80
TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer. Oncogene (2007) 2.71
Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation. Nucleic Acids Res (1996) 2.65
New ultrastructural characteristics of cells fixed in a glutaraldehyde-osmium tetroxide mixture. Lab Invest (1966) 2.51
Mouse liver cell culture. I. Hepatocyte isolation. In Vitro (1981) 2.50
p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer. Mutat Res (1999) 2.36
Benzo(a)pyrene diol epoxides as intermediates in nucleic acid binding in vitro and in vivo. Science (1976) 2.34
Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease. Cancer Res (2000) 2.31
Renal tubular lesions caused by mercuric chloride. Electron microscopic observations: degeneration of the pars recta. Am J Pathol (1968) 2.29
Evolutionary conservation and somatic mutation hotspot maps of p53: correlation with p53 protein structural and functional features. Oncogene (1999) 2.19
Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects. Nucleic Acids Res (1997) 2.17
Frequent nitric oxide synthase-2 expression in human colon adenomas: implication for tumor angiogenesis and colon cancer progression. Cancer Res (1998) 2.15
The ultrastructure of the functioning kidney. Lab Invest (1967) 2.14
Improved SPECT quantification using compensation for scattered photons. J Nucl Med (1984) 2.14
Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45. Oncogene (1999) 2.12
Relationship between p53 mutations and inducible nitric oxide synthase expression in human colorectal cancer. J Natl Cancer Inst (1999) 2.10
Frequent mutation of the p53 gene in human esophageal cancer. Proc Natl Acad Sci U S A (1990) 2.07
Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals. Environ Health Perspect (1999) 2.03
Meta- and pooled analysis of GSTT1 and lung cancer: a HuGE-GSEC review. Am J Epidemiol (2006) 2.02
DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53. Proc Natl Acad Sci U S A (2001) 2.00
Altered differentiation of mouse epidermal cells treated with retinyl acetate in vitro. Exp Cell Res (1974) 1.94
Transformation of human bronchial epithelial cells transfected by Harvey ras oncogene. Science (1985) 1.88
Establishment and characterization of SV40 T-antigen immortalized human esophageal epithelial cells. Cancer Res (1991) 1.88
The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I. J Biol Chem (1999) 1.84
Altered expression of the cyclin D1 and retinoblastoma genes in human esophageal cancer. Proc Natl Acad Sci U S A (1993) 1.84
p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines. Carcinogenesis (1993) 1.84
Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma. Clin Cancer Res (2000) 1.81
Observations on the application to electron microscopy on the lead phosphate technique for the demonstration of acid phosphatase. Histochemie (1965) 1.81
"Thanatosomes": a unifying morphogenetic concept for tumor hyaline globules related to apoptosis. Hum Pathol (2000) 1.77
Differential DNA sequence deletions from chromosomes 3, 11, 13, and 17 in squamous-cell carcinoma, large-cell carcinoma, and adenocarcinoma of the human lung. Proc Natl Acad Sci U S A (1989) 1.73
Simian virus 40 large tumor antigen-immortalized normal human liver epithelial cells express hepatocyte characteristics and metabolize chemical carcinogens. Proc Natl Acad Sci U S A (1993) 1.71
Structures of benzo(a)pyrene--nucleic acid adducts formed in human and bovine bronchial explants. Nature (1977) 1.68
Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53. Proc Natl Acad Sci U S A (1996) 1.68
High-frequency transfection and cytopathology of the hepatitis B virus core antigen gene in human cells. Science (1983) 1.67
Intermediate filament and cross-linked envelope expression in human lung tumor cell lines. Cancer Res (1985) 1.66
Deletions and insertions in the p53 tumor suppressor gene in human cancers: confirmation of the DNA polymerase slippage/misalignment model. Cancer Res (1996) 1.65
Abrogation of p53-induced apoptosis by the hepatitis B virus X gene. Cancer Res (1995) 1.64
Human bronchial epithelial cells with integrated SV40 virus T antigen genes retain the ability to undergo squamous differentiation. Differentiation (1988) 1.64
Molecular epidemiology of human cancer: contribution of mutation spectra studies of tumor suppressor genes. Cancer Res (1998) 1.64
The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway. Genes Dev (1996) 1.63
Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer. J Pathol (1999) 1.62
Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis. Proc Natl Acad Sci U S A (1997) 1.60
Asbestos-associated chromosomal changes in human mesothelial cells. Proc Natl Acad Sci U S A (1985) 1.60
Ultrasensitive enzymatic radioimmunoassay: application to detection of cholera toxin and rotavirus. Proc Natl Acad Sci U S A (1979) 1.58
Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines. Int J Cancer (1994) 1.57
Cancer risk and low-penetrance susceptibility genes in gene-environment interactions. J Clin Oncol (2000) 1.56
p53 mutations in lung cancers from non-smoking atomic-bomb survivors. Lancet (1994) 1.56
p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells. Nat Med (1998) 1.55
DNA repair polymorphisms and cancer risk in non-smokers in a cohort study. Carcinogenesis (2005) 1.54
Detection of benzo[a]pyrene diol epoxide-DNA adducts in peripheral blood lymphocytes and antibodies to the adducts in serum from coke oven workers. Proc Natl Acad Sci U S A (1985) 1.54
Mutations of p53 and ras genes in radon-associated lung cancer from uranium miners. Lancet (1992) 1.53
Geographic variation of p53 mutational profile in nonmalignant human liver. Science (1994) 1.51
Establishment of a human in vitro mesothelial cell model system for investigating mechanisms of asbestos-induced mesothelioma. Am J Pathol (1989) 1.51
Explant culture of human colon. Gastroenterology (1978) 1.50
Conformation-dependent phosphorylation of p53. Proc Natl Acad Sci U S A (1997) 1.49
Defective interplay of activators and repressors with TFIH in xeroderma pigmentosum. Cell (2001) 1.47
Disorders of cell volume regulation. I. Effects of inhibition of plasma membrane adenosine triphosphatase with ouabain. Am J Pathol (1968) 1.45
Human renal ultrastructure. I. Proximal tubule of healthy individuals. Lab Invest (1966) 1.45
Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases. Proc Natl Acad Sci U S A (2000) 1.44
Interaction of p53 with the human Rad51 protein. Nucleic Acids Res (1997) 1.43
Archival analysis of p53 genetic and protein alterations in Chinese esophageal cancer. Oncogene (1991) 1.40
Bombesin and the C-terminal tetradecapeptide of gastrin-releasing peptide are growth factors for normal human bronchial epithelial cells. Exp Cell Res (1984) 1.40
p53-mediated apoptosis is attenuated in Werner syndrome cells. Genes Dev (1999) 1.39
Strontium phosphate transfection of human cells in primary culture: stable expression of the simian virus 40 large-T-antigen gene in primary human bronchial epithelial cells. Mol Cell Biol (1987) 1.39
Functional interaction of p53 and BLM DNA helicase in apoptosis. J Biol Chem (2001) 1.37
Inflammation and oxidative stress in carcinogenesis. Cancer Cells (1991) 1.37
Cancer risk and occupational exposure to aflatoxins in Denmark. Br J Cancer (1988) 1.37
Interlaboratory comparison of antisera and immunoassays for benzo[a]pyrene-diol-epoxide-I-modified DNA. Carcinogenesis (1988) 1.37
Studies on cellular autophagocytosis. Relationship between heterophagy and autophagy in HeLa cells. Lab Invest (1971) 1.35
The respiratory epithelium. V. Histogenesis of lung carcinomas in the human. J Natl Cancer Inst (1978) 1.35
Genetic polymorphisms in DNA repair genes and risk of lung cancer. Carcinogenesis (2001) 1.35
Clonal growth of epithelial cells from normal adult human bronchus. Cancer Res (1981) 1.33
The glomerular capillary wall in human kidney disease: acute glomerulonephritis, systemic lupus erythematosus, and preeclampsia-eclampsia. Comparative electron microscopic observations and a review. Lab Invest (1966) 1.33
Studies of mouse liver necrosis in vitro. Ultrastructural and cytochemical alterations in hepatic parenchymal cell nuclei. Lab Invest (1965) 1.33