PubRank

P Hainaut

Author PubWeight™ 114.33‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mandated lowering of toxicants in cigarette smoke: a description of the World Health Organization TobReg proposal. Tob Control 2008 4.37
2 TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes. Oncogene 2007 4.27
3 Transfection and expression of a gene coding for a human melanoma antigen recognized by autologous cytolytic T lymphocytes. Immunogenetics 1992 2.45
4 Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study. Diabetologia 2011 2.43
5 Environmental tobacco smoke and risk of respiratory cancer and chronic obstructive pulmonary disease in former smokers and never smokers in the EPIC prospective study. BMJ 2005 2.22
6 Recent advances in p53 research: an interdisciplinary perspective. Cancer Gene Ther 2008 1.88
7 Hepatocellular carcinoma: from gene to public health. J Natl Cancer Inst 1997 1.86
8 Genetic alterations in esophageal cancer and their relevance to etiology and pathogenesis: a review. Int J Cancer 1996 1.82
9 Presence on a human melanoma of multiple antigens recognized by autologous CTL. Int J Cancer 1989 1.80
10 New approaches to understanding p53 gene tumor mutation spectra. Mutat Res 1999 1.75
11 Biological functions of p53 isoforms through evolution: lessons from animal and cellular models. Cell Death Differ 2011 1.74
12 Genetic steps in the development of squamous cell carcinoma of the esophagus. Mutat Res 2000 1.73
13 Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma. Br J Cancer 2008 1.59
14 Precursor frequency analysis of human cytolytic T lymphocytes directed against autologous melanoma cells. Int J Cancer 1992 1.57
15 TP53: a key gene in human cancer. Biochimie 2002 1.50
16 IARC p53 mutation database: a relational database to compile and analyze p53 mutations in human tumors and cell lines. International Agency for Research on Cancer. Hum Mutat 1999 1.48
17 Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies. Cancer Gene Ther 2010 1.41
18 Differences in the antigens recognized by cytolytic T cells on two successive metastases of a melanoma patient are consistent with immune selection. Eur J Immunol 1995 1.39
19 The multidisciplinary management of gastrointestinal cancer. Epidemiology of oesophagogastric cancer. Best Pract Res Clin Gastroenterol 2007 1.36
20 Properties of the six isoforms of p63: p53-like regulation in response to genotoxic stress and cross talk with DeltaNp73. Carcinogenesis 2007 1.34
21 Up-regulation of Fas (APO-1/CD95) ligand and down-regulation of Fas expression in human esophageal cancer. Cancer Res 1998 1.29
22 p53 regulates the transcription of its Delta133p53 isoform through specific response elements contained within the TP53 P2 internal promoter. Oncogene 2010 1.26
23 Genotoxic and non-genotoxic pathways of p53 induction. Cancer Lett 2001 1.25
24 Ser-249 p53 mutations in plasma DNA of patients with hepatocellular carcinoma from The Gambia. J Natl Cancer Inst 2000 1.23
25 Overweight, obesity and risk of premenopausal breast cancer according to ethnicity: a systematic review and dose-response meta-analysis. Obes Rev 2013 1.23
26 Metalloregulation of the tumor suppressor protein p53: zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells. Oncogene 2000 1.21
27 Regulation of p53 by metal ions and by antioxidants: dithiocarbamate down-regulates p53 DNA-binding activity by increasing the intracellular level of copper. Mol Cell Biol 1997 1.19
28 Inactivation of the p53 protein in cell lines derived from human esophageal cancers. Int J Cancer 1997 1.13
29 Transcriptional activation of cyclooxygenase-2 by tumor suppressor p53 requires nuclear factor-kappaB. Oncogene 2006 1.13
30 Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells. J Biol Chem 1999 1.12
31 Distinct pattern of TP53 mutations in squamous cell carcinoma of the esophagus in Iran. Oncogene 2001 1.12
32 BTG gene expression in the p53-dependent and -independent cellular response to DNA damage. Mol Carcinog 2000 1.12
33 Nitric oxide induces conformational and functional modifications of wild-type p53 tumor suppressor protein. Cancer Res 1997 1.11
34 Hepatitis B viral load and risk for liver cirrhosis and hepatocellular carcinoma in The Gambia, West Africa. J Viral Hepat 2009 1.10
35 TP53 PIN3 and MDM2 SNP309 polymorphisms as genetic modifiers in the Li-Fraumeni syndrome: impact on age at first diagnosis. J Med Genet 2009 1.10
36 Mutant p53 reactivation by PRIMA-1MET induces multiple signaling pathways converging on apoptosis. Oncogene 2009 1.10
37 Effects of tobacco smoke and benzo[a]pyrene on human endothelial cell and monocyte stress responses. Am J Physiol Heart Circ Physiol 2001 1.09
38 TP53, EGFR, and KRAS mutations in relation to VHL inactivation and lifestyle risk factors in renal-cell carcinoma from central and eastern Europe. Cancer Lett 2010 1.05
39 Lung tumor KRAS and TP53 mutations in nonsmokers reflect exposure to PAH-rich coal combustion emissions. Cancer Res 2001 1.04
40 Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation. Cell Death Differ 2012 1.02
41 Absence of association between HPV DNA, TP53 codon 72 polymorphism, and risk of oesophageal cancer in a high-risk area of China. Cancer Lett 2001 1.01
42 Redox signalling and transition metals in the control of the p53 pathway. Biochem Pharmacol 2000 1.00
43 Quantitative analysis of DNA methylation after whole bisulfitome amplification of a minute amount of DNA from body fluids. Epigenetics 2009 1.00
44 Molecular and clinical differences between adenocarcinomas of the esophagus and of the gastric cardia. Am J Pathol 2001 1.00
45 Nitric oxide nitrates tyrosine residues of tumor-suppressor p53 protein in MCF-7 cells. Biochem Biophys Res Commun 2000 0.99
46 Esophageal cancer: cases and causes (part I). Endoscopy 2007 0.99
47 TP53 and long-term prognosis in colorectal cancer: mutations in the L3 zinc-binding domain predict poor survival. Clin Cancer Res 1998 0.98
48 p53 isoforms - a conspiracy to kidnap p53 tumor suppressor activity? Cell Mol Life Sci 2009 0.98
49 TP53 PIN3 and PEX4 polymorphisms and infertility associated with endometriosis or with post-in vitro fertilization implantation failure. Cell Death Dis 2012 0.95
50 TP53 mutation patterns in breast cancers: searching for clues of environmental carcinogenesis. Semin Cancer Biol 2001 0.94
51 Hepatitis B surface antigenaemia and alpha-foetoprotein detection from dried blood spots: applications to field-based studies and to clinical care in hepatitis B virus endemic areas. J Viral Hepat 2005 0.92
52 Cadmium in the environment: sources, mechanisms of biotoxicity, and biomarkers. Rev Environ Health 2001 0.92
53 TP53 mutations, amplification of P63 and expression of cell cycle proteins in squamous cell carcinoma of the oesophagus from a low incidence area in Western Europe. Br J Cancer 2001 0.92
54 Modulation of p53 protein conformation and DNA-binding activity by intracellular chelation of zinc. Mol Carcinog 1998 0.91
55 A specific spectrum of p53 mutations in lung cancer from smokers: review of mutations compiled in the IARC p53 database. Environ Health Perspect 1998 0.91
56 Using dual-detector helical CT angiography to detect deep venous thrombosis in patients with suspicion of pulmonary embolism: diagnostic value and additional findings. AJR Am J Roentgenol 2001 0.91
57 The cytoprotective aminothiol WR1065 activates p21waf-1 and down regulates cell cycle progression through a p53-dependent pathway. Oncogene 2000 0.90
58 EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration. Eur Respir J 2009 0.89
59 TP53 mutations and MDM2 gene amplification in squamous-cell carcinomas of the esophagus in south Thailand. Int J Cancer 2000 0.89
60 Premalignant lesions of the esophagogastric mucosa. Semin Oncol 2004 0.89
61 Lymphocytic gastritis: an unusual cause of hypoproteinaemia. J Intern Med 1993 0.89
62 Mutation spectra resulting from carcinogenic exposure: from model systems to cancer-related genes. Recent Results Cancer Res 1998 0.88
63 p53 and cell-cycle control: a finger in every pie. Pathol Biol (Paris) 2000 0.88
64 Mutant p53 protein, master regulator of human malignancies: a report on the Fifth Mutant p53 Workshop. Cell Death Differ 2011 0.87
65 Relationships between lung adenocarcinoma and gender, age, smoking and occupational risk factors: A case-case study. Lung Cancer 2009 0.87
66 Low frequency of p16/CDKN2 gene mutations in esophageal carcinomas. Int J Cancer 1996 0.86
67 Insulin binding to its receptor induces a conformational change in the receptor C-terminus. Biochemistry 1990 0.86
68 Peroral infection of suckling mice with milk-borne mouse mammary tumour virus: uptake of the main viral antigens by the gut. J Gen Virol 1983 0.86
69 TP53 polymorphism, HPV infection, and risk of cervical cancer. Cancer Epidemiol Biomarkers Prev 2001 0.85
70 TP53 mutation spectrum in lung cancers and mutagenic signature of components of tobacco smoke: lessons from the IARC TP53 mutation database. Mutagenesis 2001 0.85
71 Application of a novel, rapid, and sensitive oligonucleotide ligation assay for detection of cancer-predicting mutations in the precore and basal core promoter of hepatitis B virus. J Clin Microbiol 2008 0.85
72 Methodology of laboratory measurements in prospective studies on gene-environment interactions: the experience of GenAir. Mutat Res 2005 0.85
73 [Epidemiology, prevention, screening and diagnosis of hepatocellular carcinoma]. Bull Cancer 2009 0.85
74 Amifostine (WR2721) restores transcriptional activity of specific p53 mutant proteins in a yeast functional assay. Oncogene 2001 0.85
75 Circulating lupus type anticoagulant and pulmonary hypertension associated with mixed connective tissue disease. Clin Rheumatol 1986 0.84
76 A meta-analysis of cancer risk associated with the TP53 intron 3 duplication polymorphism (rs17878362): geographic and tumor-specific effects. Cell Death Dis 2013 0.84
77 Regulation of body temperature after acute organophosphate poisoning. Can J Anaesth 1996 0.83
78 TP53 and EGFR mutations in combination with lifestyle risk factors in tumours of the upper aerodigestive tract from South America. Carcinogenesis 2009 0.83
79 First International p53 Isoforms Meeting: 'p53 isoforms through evolution: from identification to biological function'. Cell Death Differ 2010 0.83
80 A sample storage management system for biobanks. Bioinformatics 2010 0.83
81 Natural infection of Swiss mice with mouse mammary tumor virus (MMTV): viral expression in milk and transmission of infection. Arch Virol 1985 0.83
82 TP63 P2 promoter functional analysis identifies β-catenin as a key regulator of ΔNp63 expression. Oncogene 2011 0.82
83 Molecular precursor lesions in oesophageal cancer. Cancer Surv 1998 0.82
84 Metal ions as regulators of the conformation and function of the tumour suppressor protein p53: implications for carcinogenesis. Proc Nutr Soc 1999 0.81
85 Antigenic heterogeneity of a human melanoma tumor detected by autologous CTL clones. Eur J Immunol 1988 0.81
86 Esophageal cancer: the precursors (Part II). Endoscopy 2007 0.81
87 Increased salt concentration reversibly destabilizes p53 quaternary structure and sequence-specific DNA binding. Biochem J 1994 0.80
88 Temporary vena caval filtration. Preliminary clinical experience with removable vena caval filters. Acta Clin Belg 1999 0.80
89 Assessment of transformed properties in vitro and of tumorigenicity in vivo in primary keratinocytes cultured for epidermal sheet transplantation. J Skin Cancer 2010 0.80
90 Sources of bias in the detection and reporting of p53 mutations in human cancer: analysis of the IARC p53 mutation database. Genet Anal 1999 0.80
91 Prostate abscess following intravesical BCG therapy. Acta Clin Belg 2009 0.79
92 Increased uptake of indium-111 pentetreotide up to 10 years after external thoracic irradiation: report of two cases. Eur J Nucl Med 1996 0.79
93 Nitric oxide prevents gamma-radiation-induced cell cycle arrest by impairing p53 function in MCF-7 cells. Biochem Biophys Res Commun 2001 0.79
94 Somatic mutation databases as tools for molecular epidemiology and molecular pathology of cancer: proposed guidelines for improving data collection, distribution, and integration. Hum Mutat 2009 0.79
95 The first case of Li-Fraumeni syndrome in Bosnia and Herzegovina: case report. Pathologica 2006 0.78
96 Rarity and potential severity of Gemella haemolysans endocarditis. Acta Clin Belg 1993 0.78
97 Molecular etiopathogenesis of esophageal cancers. Ann Ist Super Sanita 1996 0.78
98 Chronic aortic dissection masquerading as systemic disease. Acta Clin Belg 1998 0.76
99 Antigens recognized on a melanoma cell line by autologous cytolytic T lymphocytes are also expressed on freshly collected tumor cells. Eur J Immunol 1990 0.76
100 Somatic mutations in human cancer: applications in molecular epidemiology. Rev Epidemiol Sante Publique 2005 0.76
101 Analysis of p53, p16MTS, p21WAF1 and H-ras in archived bladder tumours from workers exposed to aromatic amines. Br J Cancer 1998 0.76
102 Activation and regulation of the insulin receptor kinase. Diabete Metab 1992 0.75
103 D-lactic acidosis: an unusual cause of encephalopathy in a patient with short bowel syndrome. Acta Clin Belg 2013 0.75
104 Chemical-induced genetic alterations in human cancers: relevance to aetiology and pathogenesis. Eur J Cancer Prev 1996 0.75
105 Intravascular haemolysis in hypertrophic cardiomyopathy. Eur Heart J 1996 0.75
106 [Rivaroxaban: Xarelto--recommendations for pharmacists]. J Pharm Belg 2013 0.75
107 Evaluation of tumorigenic risk of tissue-engineered oral mucosal epithelial cells by using combinational examinations. Cell Transplant 2010 0.75
108 Aortic mural thrombi associated with ulcerative colitis. Acta Clin Belg 2010 0.75
109 Identification of genes encoding T cell defined tum- antigens. Princess Takamatsu Symp 1988 0.75
110 [Renal insufficiency manifesting a heterozygote form of Fabry's disease]. Acta Clin Belg 1988 0.75
111 Analysis of somatic mutations of the p53 gene in human cancers: a tool to generate hypotheses about the natural history of cancer. IARC Sci Publ 1999 0.75
112 Acute renal failure due to diffuse extramedullary plasmocytoma. Acta Clin Belg 2013 0.75
113 ELISA D-dimer measurement for the clinical suspicion of pulmonary embolism in the emergency department: one-year observational study of the safety profile and physician's prescription. Acta Clin Belg 2003 0.75
114 Hereditary paraganglioma. J Intern Med 1999 0.75
115 Anti-tumor immune response. Acta Clin Belg 1993 0.75
116 Statin-induced rhabdomyolysis mimicking polymyositis on (18)F-FDG PET imaging. Acta Clin Belg 2014 0.75
117 Among the human antibodies reacting with intracytoplasmic a particles of mouse mammary tumor virus, some react with MMTV p14, the nucleic-acid-binding protein, and others with MMTV p28, the main core protein. Int J Cancer 1983 0.75
118 Nocardiosis: a rare cause of pleuropulmonary disease in the immunocompromised host. Acta Clin Belg 1996 0.75
119 Low-molecular-weight heparin-induced skin necrosis: about 2 cases. Acta Clin Belg 2009 0.75
120 Heparin-induced thrombocytopaenia complicated by arterial and venous thrombosis: report of 2 cases successfully treated by a danaparoid sodium. Acta Clin Belg 2000 0.75
121 The use of biomarkers to study pathogenesis and mechanisms of cancer: oesophagus and skin cancer as models. IARC Sci Publ 1997 0.75
122 Simultaneous occurrence of metastatic breast cancer, Hodgkin's disease and tuberculous lymphadenitis in homolateral axillary lymph nodes--a case report. Acta Clin Belg 2009 0.75
123 Poststreptococcal reactive arthritis: a form of acute rheumatic fever in adulthood. Acta Clin Belg 1995 0.75