Charbel E-H Moussa

Author PubWeight™ 41.67‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012 20.08
2 Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury. Nat Med 2009 1.95
3 Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of α-synuclein in Parkinson's disease models. Hum Mol Genet 2013 1.94
4 Inflammation in the early stages of neurodegenerative pathology. J Neuroimmunol 2011 1.21
5 Parkin promotes intracellular Abeta1-42 clearance. Hum Mol Genet 2009 1.18
6 Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Abeta in AD models. Hum Mol Genet 2011 1.12
7 Beta-amyloid1-42 gene transfer model exhibits intraneuronal amyloid, gliosis, tau phosphorylation, and neuronal loss. J Biol Chem 2010 1.05
8 Diminished parkin solubility and co-localization with intraneuronal amyloid-β are associated with autophagic defects in Alzheimer's disease. J Alzheimers Dis 2013 1.01
9 Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells. J Biol Chem 2006 1.01
10 Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6). J Biol Chem 2012 0.97
11 The role of alpha-synuclein in both neuroprotection and neurodegeneration. Ann N Y Acad Sci 2004 0.97
12 Tyrosine kinase inhibition increases functional parkin-Beclin-1 interaction and enhances amyloid clearance and cognitive performance. EMBO Mol Med 2013 0.96
13 Parkin reverses intracellular beta-amyloid accumulation and its negative effects on proteasome function. J Neurosci Res 2010 0.93
14 Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearance. J Mol Med (Berl) 2013 0.89
15 Parkin reverses TDP-43-induced cell death and failure of amino acid homeostasis. J Neurochem 2013 0.88
16 β-amyloid triggers ALS-associated TDP-43 pathology in AD models. Brain Res 2011 0.88
17 Tyrosine kinase inhibition facilitates autophagic SNCA/α-synuclein clearance. Autophagy 2013 0.87
18 Fractalkine Mediates Communication between Pathogenic Proteins and Microglia: Implications of Anti-Inflammatory Treatments in Different Stages of Neurodegenerative Diseases. Int J Alzheimers Dis 2012 0.85
19 Wild type and P301L mutant Tau promote neuro-inflammation and α-Synuclein accumulation in lentiviral gene delivery models. Mol Cell Neurosci 2011 0.85
20 Mitochondrial dysfunction in skeletal muscle of amyloid precursor protein-overexpressing mice. J Biol Chem 2012 0.84
21 Wild type TDP-43 induces neuro-inflammation and alters APP metabolism in lentiviral gene transfer models. Exp Neurol 2012 0.81
22 Parkin prevents cortical atrophy and Aβ-induced alterations of brain metabolism: ¹³C NMR and magnetic resonance imaging studies in AD models. Neuroscience 2012 0.78
23 The Relationship between Parkin and Protein Aggregation in Neurodegenerative Diseases. Front Psychiatry 2010 0.76