Published in Nat Rev Immunol on February 01, 2005
Current status of vaccines for schistosomiasis. Clin Microbiol Rev (2008) 3.47
Tetraspanins: push and pull in suppressing and promoting metastasis. Nat Rev Cancer (2008) 3.04
Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling. J Cell Biol (2010) 2.85
Mapping of tetraspanin-enriched microdomains that can function as gateways for HIV-1. J Cell Biol (2006) 2.38
The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascade. J Biol Chem (2007) 2.24
Routes and mechanisms of extracellular vesicle uptake. J Extracell Vesicles (2014) 2.11
CD81 is a central regulator of cellular events required for hepatitis C virus infection of human hepatocytes. J Virol (2008) 2.09
Diverse CD81 proteins support hepatitis C virus infection. J Virol (2006) 2.07
GPR56 regulates pial basement membrane integrity and cortical lamination. J Neurosci (2008) 1.93
Targeting of tetraspanin proteins--potential benefits and strategies. Nat Rev Drug Discov (2008) 1.91
The CD81 partner EWI-2wint inhibits hepatitis C virus entry. PLoS One (2008) 1.86
Uroplakins in urothelial biology, function, and disease. Kidney Int (2009) 1.79
Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms. J Cell Biol (2008) 1.75
CD81 and claudin 1 coreceptor association: role in hepatitis C virus entry. J Virol (2008) 1.62
A comprehensive transcriptome and immune-gene repertoire of the lepidopteran model host Galleria mellonella. BMC Genomics (2011) 1.59
Tetraspanins in extracellular vesicle formation and function. Front Immunol (2014) 1.56
Gene discovery for the carcinogenic human liver fluke, Opisthorchis viverrini. BMC Genomics (2007) 1.35
Structural basis for tetraspanin functions as revealed by the cryo-EM structure of uroplakin complexes at 6-A resolution. J Cell Biol (2006) 1.34
Syntenin-1 is a new component of tetraspanin-enriched microdomains: mechanisms and consequences of the interaction of syntenin-1 with CD63. Mol Cell Biol (2006) 1.32
Laminin-binding integrins and their tetraspanin partners as potential antimetastatic targets. Expert Rev Mol Med (2010) 1.30
A virulent strain of deformed wing virus (DWV) of honeybees (Apis mellifera) prevails after Varroa destructor-mediated, or in vitro, transmission. PLoS Pathog (2014) 1.28
Tetraspanin12 regulates ADAM10-dependent cleavage of amyloid precursor protein. FASEB J (2009) 1.28
Why is delta endocytosis required for effective activation of notch? Dev Dyn (2006) 1.27
Tetraspanin CD81 is required for the alpha v beta5-integrin-dependent particle-binding step of RPE phagocytosis. J Cell Sci (2007) 1.24
Arabidopsis plasmodesmal proteome. PLoS One (2011) 1.22
Parasitization by the wasp Eretmocerus mundus induces transcription of genes related to immune response and symbiotic bacteria proliferation in the whitefly Bemisia tabaci. BMC Genomics (2008) 1.20
Identification of a polyI:C-inducible membrane protein that participates in dendritic cell-mediated natural killer cell activation. J Exp Med (2010) 1.20
DHHC2 affects palmitoylation, stability, and functions of tetraspanins CD9 and CD151. Mol Biol Cell (2008) 1.19
Complete predicted three-dimensional structure of the facilitator transmembrane protein and hepatitis C virus receptor CD81: conserved and variable structural domains in the tetraspanin superfamily. Biophys J (2006) 1.18
Oncologic trogocytosis of an original stromal cells induces chemoresistance of ovarian tumours. PLoS One (2008) 1.17
Building of the tetraspanin web: distinct structural domains of CD81 function in different cellular compartments. Mol Cell Biol (2006) 1.17
Relationships between plasma membrane microdomains and HIV-1 assembly. Biol Cell (2010) 1.16
GATA factors participate in tissue-specific immune responses in Drosophila larvae. Proc Natl Acad Sci U S A (2006) 1.13
Protein kinase A-dependent step(s) in hepatitis C virus entry and infectivity. J Virol (2008) 1.12
HIV-1 Assembly at the Plasma Membrane: Gag Trafficking and Localization. Future Virol (2009) 1.11
HIV-1 assembly differentially alters dynamics and partitioning of tetraspanins and raft components. Traffic (2010) 1.11
Scavenger receptor class B is required for hepatitis C virus uptake and cross-presentation by human dendritic cells. J Virol (2008) 1.09
Engagement of CD81 induces ezrin tyrosine phosphorylation and its cellular redistribution with filamentous actin. J Cell Sci (2009) 1.05
Hepatocyte permissiveness to Plasmodium infection is conveyed by a short and structurally conserved region of the CD81 large extracellular domain. PLoS Pathog (2008) 1.05
Whole transcriptome profiling of successful immune response to Vibrio infections in the oyster Crassostrea gigas by digital gene expression analysis. PLoS One (2011) 1.04
Tetraspanin CD151 regulates growth of mammary epithelial cells in three-dimensional extracellular matrix: implication for mammary ductal carcinoma in situ. Cancer Res (2010) 1.03
Primary hepatocytes as targets for hepatitis C virus replication. J Viral Hepat (2008) 1.03
The crucial role of the Pls1 tetraspanin during ascospore germination in Podospora anserina provides an example of the convergent evolution of morphogenetic processes in fungal plant pathogens and saprobes. Eukaryot Cell (2008) 1.01
Spatiotemporal resolution of mast cell granule exocytosis reveals correlation with Ca2+ wave initiation. J Cell Sci (2012) 1.01
Intron evolution: testing hypotheses of intron evolution using the phylogenomics of tetraspanins. PLoS One (2009) 1.00
Human immunodeficiency virus type 1 and influenza virus exit via different membrane microdomains. J Virol (2007) 1.00
Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains. Biochem J (2009) 1.00
Fungi have three tetraspanin families with distinct functions. BMC Genomics (2008) 0.99
Sarcospan reduces dystrophic pathology: stabilization of the utrophin-glycoprotein complex. J Cell Biol (2008) 0.99
Genome-wide RNAi screen identifies novel host proteins required for alphavirus entry. PLoS Pathog (2013) 0.99
Activation of peripheral-blood granulocytes is strongly correlated with patient outcome after immunotherapy with anti-GD2 monoclonal antibody and granulocyte-macrophage colony-stimulating factor. J Clin Oncol (2011) 0.99
Fertilization Mechanisms in Flowering Plants. Curr Biol (2016) 0.98
Nanoscale arrangement of apoptotic ligands reveals a demand for a minimal lateral distance for efficient death receptor activation. Nano Lett (2009) 0.98
The tetraspanin Tm4sf3 is localized to the ventral pancreas and regulates fusion of the dorsal and ventral pancreatic buds. Development (2009) 0.97
High-level expression, single-step immunoaffinity purification and characterization of human tetraspanin membrane protein CD81. PLoS One (2008) 0.97
Gangliosides play an important role in the organization of CD82-enriched microdomains. Biochem J (2006) 0.96
Membrane-Associated RING-CH proteins associate with Bap31 and target CD81 and CD44 to lysosomes. PLoS One (2010) 0.95
Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells. Mol Cell Proteomics (2009) 0.95
CD82 endocytosis and cholesterol-dependent reorganization of tetraspanin webs and lipid rafts. FASEB J (2009) 0.95
CD81/CD9 tetraspanins aid plasmacytoid dendritic cells in recognition of hepatitis C virus-infected cells and induction of interferon-alpha. Hepatology (2013) 0.93
Interacting regions of CD81 and two of its partners, EWI-2 and EWI-2wint, and their effect on hepatitis C virus infection. J Biol Chem (2011) 0.92
Major histocompatibility complex class I downregulation induced by equine herpesvirus type 1 pUL56 is through dynamin-dependent endocytosis. J Virol (2014) 0.92
Mutation of juxtamembrane cysteines in the tetraspanin CD81 affects palmitoylation and alters interaction with other proteins at the cell surface. Exp Cell Res (2009) 0.92
Dual function of CD81 in influenza virus uncoating and budding. PLoS Pathog (2013) 0.92
Determination of protein regions responsible for interactions of amelogenin with CD63 and LAMP1. Biochem J (2007) 0.92
CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway. PLoS Biol (2011) 0.91
Arabidopsis tetraspanins are confined to discrete expression domains and cell types in reproductive tissues and form homo- and heterodimers when expressed in yeast. Plant Physiol (2013) 0.91
Uropathogenic E. coli adhesin-induced host cell receptor conformational changes: implications in transmembrane signaling transduction. J Mol Biol (2009) 0.90
Hepatoma polarization limits CD81 and hepatitis C virus dynamics. Cell Microbiol (2012) 0.90
CD9 clustering and formation of microvilli zippers between contacting cells regulates virus-induced cell fusion. Traffic (2008) 0.90
Tetraspanin CD9 links junctional adhesion molecule-A to αvβ3 integrin to mediate basic fibroblast growth factor-specific angiogenic signaling. Mol Biol Cell (2013) 0.90
The roles of tetraspanins in HIV-1 replication. Curr Top Microbiol Immunol (2009) 0.89
Expression and function of CD9 in melanoma cells. Mol Carcinog (2010) 0.89
Epithelial membrane protein-2 promotes endometrial tumor formation through activation of FAK and Src. PLoS One (2011) 0.89
The tetraspanins CD151 and Tspan8 are essential exosome components for the crosstalk between cancer initiating cells and their surrounding. Oncotarget (2015) 0.89
Functional consequences of interactions between FAK and epithelial membrane protein 2 (EMP2). Invest Ophthalmol Vis Sci (2009) 0.89
Profiling of the tetraspanin CD151 web and conspiracy of CD151/integrin β1 complex in the progression of hepatocellular carcinoma. PLoS One (2011) 0.89
The tetraspanin web revisited by super-resolution microscopy. Sci Rep (2015) 0.89
Autoimmune manifestations in viral hepatitis. Semin Immunopathol (2012) 0.88
Noncytotoxic suppression of human immunodeficiency virus type 1 transcription by exosomes secreted from CD8+ T cells. J Virol (2009) 0.88
Loss of Col3a1, the gene for Ehlers-Danlos syndrome type IV, results in neocortical dyslamination. PLoS One (2012) 0.88
The tetraspanins CD9 and CD81 regulate CD9P1-induced effects on cell migration. PLoS One (2010) 0.88
Identification of novel cell-adhesion molecules in peripheral nerves using a signal-sequence trap. Neuron Glia Biol (2006) 0.88
The first transmembrane region of the beta-chain stabilizes the tetrameric Fc epsilon RI complex. Mol Immunol (2009) 0.87
The association of CD81 with tetraspanin-enriched microdomains is not essential for Hepatitis C virus entry. BMC Microbiol (2009) 0.87
CD9 tetraspanin interacts with CD36 on the surface of macrophages: a possible regulatory influence on uptake of oxidized low density lipoprotein. PLoS One (2011) 0.86
CD81 controls sustained T cell activation signaling and defines the maturation stages of cognate immunological synapses. Mol Cell Biol (2013) 0.86
Molecular characterization of a tetraspanin from the human liver fluke, Opisthorchis viverrini. PLoS Negl Trop Dis (2012) 0.86
Targeting HCV entry for development of therapeutics. Viruses (2010) 0.86
Structural characterization of recombinant human CD81 produced in Pichia pastoris. Protein Expr Purif (2007) 0.85
Replication study confirms link between TSPAN18 mutation and schizophrenia in Han Chinese. PLoS One (2013) 0.85
The tetraspanin CD81 protein increases melanoma cell motility by up-regulating metalloproteinase MT1-MMP expression through the pro-oncogenic Akt-dependent Sp1 activation signaling pathways. J Biol Chem (2014) 0.85
Entry inhibitors: New advances in HCV treatment. Emerg Microbes Infect (2016) 0.84
CD81 and hepatitis C virus (HCV) infection. Viruses (2014) 0.84
The extracellular δ-domain is essential for the formation of CD81 tetraspanin webs. Biophys J (2014) 0.84
Novel function of CD81 in controlling hepatitis C virus replication. J Virol (2010) 0.84
CD81 protein is expressed at high levels in normal germinal center B cells and in subtypes of human lymphomas. Hum Pathol (2009) 0.83
The tetraspanin CD82 is specifically recruited to fungal and bacterial phagosomes prior to acidification. Infect Immun (2010) 0.83
CD81-receptor associations--impact for hepatitis C virus entry and antiviral therapies. Viruses (2014) 0.83
Structural and functional analysis of the sarcoglycan-sarcospan subcomplex. Exp Cell Res (2006) 0.83
Protein-protein interactions in the tetraspanin web. Physiology (Bethesda) (2005) 1.79
The tetraspanin CD81 is necessary for partitioning of coligated CD19/CD21-B cell antigen receptor complexes into signaling-active lipid rafts. J Immunol (2004) 1.23
Structural and functional bases for allosteric control of MMP activities: can it pave the path for selective inhibition? Biochim Biophys Acta (2009) 1.15
Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential. Nat Med (2011) 0.99
The CD9 tetraspanin is not required for the development of peripheral B cells or for humoral immunity. J Immunol (2005) 0.81
Development of allogeneic NK cell adoptive transfer therapy in metastatic melanoma patients: in vitro preclinical optimization studies. PLoS One (2013) 0.79