John C Chambers

Author PubWeight™ 164.57‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 2008 20.66
2 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 2011 13.25
3 Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet 2009 12.44
4 Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet 2010 8.55
5 Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet 2012 7.59
6 Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Nat Genet 2008 6.06
7 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009 5.81
8 Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease. JAMA 2009 5.32
9 The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am J Hum Genet 2008 4.79
10 Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. Am J Hum Genet 2008 4.69
11 Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet 2012 4.63
12 Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol 2010 4.08
13 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nat Genet 2011 3.46
14 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet 2011 3.40
15 New gene functions in megakaryopoiesis and platelet formation. Nature 2011 3.14
16 Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet 2012 3.04
17 Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 2013 2.92
18 Population-based reference values for 3D echocardiographic LV volumes and ejection fraction. JACC Cardiovasc Imaging 2012 2.92
19 Seventy-five genetic loci influencing the human red blood cell. Nature 2012 2.77
20 Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet 2011 2.73
21 Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet 2012 2.05
22 Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A 2011 2.01
23 Arrhythmogenic cardiomyopathy: etiology, diagnosis, and treatment. Annu Rev Med 2010 1.86
24 Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation 2013 1.77
25 Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet 2013 1.72
26 A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies. Genome Biol 2015 1.71
27 Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. Stroke 2013 1.51
28 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. Diabetes 2013 1.36
29 Normative reference values for the tissue Doppler imaging parameters of left ventricular function: a population-based study. Eur J Echocardiogr 2009 1.35
30 Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies. Hum Mol Genet 2013 1.34
31 Ethnicity-related differences in left ventricular function, structure and geometry: a population study of UK Indian Asian and European white subjects. Heart 2009 1.33
32 Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias. PLoS Med 2012 1.27
33 Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood 2012 1.26
34 The C-CURE Randomized Clinical Trial (Cardiopoietic stem Cell therapy in heart failURE). J Am Coll Cardiol 2013 1.26
35 A replication study of GWAS-derived lipid genes in Asian Indians: the chromosomal region 11q23.3 harbors loci contributing to triglycerides. PLoS One 2012 1.11
36 Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci. Genome Res 2013 1.10
37 Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr 2013 1.08
38 Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. PLoS Genet 2013 1.02
39 New insights into the relationship of left ventricular geometry and left ventricular mass with cardiac function: A population study of hypertensive subjects. Eur Heart J 2009 0.92
40 Guidelines in cardiac clinical practice: evaluation of their methodological quality using the AGREE II instrument. J R Soc Med 2013 0.91
41 Mutational heterogeneity, modifier genes, and environmental influences contribute to phenotypic diversity of arrhythmogenic cardiomyopathy. Circ Cardiovasc Genet 2010 0.84
42 Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis. Clin Endocrinol (Oxf) 2014 0.81
43 Fine-scale estimation of location of birth from genome-wide single-nucleotide polymorphism data. Genetics 2011 0.79
44 Ethnic and gender differences in the relationship between hostility and metabolic and autonomic risk factors for coronary heart disease. Psychosom Med 2010 0.79
45 The distinct relationships of carotid plaque disease and carotid intima-media thickness with left ventricular function. J Am Soc Echocardiogr 2010 0.79
46 Does subclinical atherosclerosis burden identify the increased risk of cardiovascular disease mortality among United Kingdom Indian Asians? A population study. Am Heart J 2011 0.78
47 The CXCL16 A181V mutation selectively inhibits monocyte adhesion to CXCR6 but is not associated with human coronary heart disease. Arterioscler Thromb Vasc Biol 2011 0.76
48 Prophylactic heparin in palliative care: ...to a challenging idea. BMJ 2006 0.75
49 Doctors and climate change: Impact of medical ethics. BMJ 2008 0.75
50 Please do not resuscitate: do we perform cardiopulmonary resuscitation on living or dead people? BMJ 2006 0.75
51 Strange things happen when we never qualify the frequency. BMJ 2006 0.75
52 Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet 2016 0.75
53 "Right to die": legal view of right to life and death could threaten philosophy of palliative care. BMJ 2005 0.75
54 A 12-hour interval between evening and morning drug rounds does not compromise symptom management. Palliat Med 2005 0.75
55 Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet 2017 0.75
56 Hydration for myoclonus. Palliat Med 2005 0.75
57 Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet 2017 0.75
58 Hospices and CPR guidelines. CPR in a hospice in perspective. BMJ 2009 0.75
59 Bacterial parotitis secondary to antisecretory medication. Palliat Med 2008 0.75
60 New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circ Cardiovasc Genet 2017 0.75
61 Magnesium sulfate via a mucous fistula in the management of short bowel syndrome. J Pain Symptom Manage 2008 0.75
62 Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels. Thromb Haemost 2016 0.75