Published in Nat Genet on January 13, 2008
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
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Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
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A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans. Hum Mol Genet (2010) 1.60
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Four additional mouse crosses improve the lipid QTL landscape and identify Lipg as a QTL gene. J Lipid Res (2009) 1.16
Genome-wide association study identifies common variants associated with circulating vitamin E levels. Hum Mol Genet (2011) 1.14
Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample. J Lipid Res (2009) 1.14
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Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP). Biochem Biophys Res Commun (2010) 1.10
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A genome-wide association analysis of Framingham Heart Study longitudinal data using multivariate adaptive splines. BMC Proc (2009) 1.08
WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels. Am J Hum Genet (2008) 1.06
A single nucleotide polymorphism in the FADS1/FADS2 gene is associated with plasma lipid profiles in two genetically similar Asian ethnic groups with distinctive differences in lifestyle. Hum Genet (2010) 1.03
Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site. Am J Hum Genet (2012) 1.01
Pleiotropic genes for metabolic syndrome and inflammation. Mol Genet Metab (2014) 1.01
Genetic determinants of phenotypic diversity in humans. Genome Biol (2008) 1.00
Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project. PLoS One (2012) 0.98
Implications of discoveries from genome-wide association studies in current cardiovascular practice. World J Cardiol (2011) 0.97
Effects of genetic variants on lipid parameters and dyslipidemia in a Chinese population. J Lipid Res (2010) 0.96
A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol. Twin Res Hum Genet (2012) 0.95
Athsq1 is an atherosclerosis modifier locus with dramatic effects on lesion area and prominent accumulation of versican. Arterioscler Thromb Vasc Biol (2008) 0.95
Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1. J Lipid Res (2009) 0.95
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Fine mapping of a linkage peak with integration of lipid traits identifies novel coronary artery disease genes on chromosome 5. BMC Genet (2012) 0.92
Relation of lipid gene scores to longitudinal trends in lipid levels and incidence of abnormal lipid levels among individuals of European ancestry: the Atherosclerosis Risk in Communities (ARIC) study. Circ Cardiovasc Genet (2011) 0.92
Sex-specific association of rs16996148 SNP in the NCAN/CILP2/PBX4 and serum lipid levels in the Mulao and Han populations. Lipids Health Dis (2011) 0.91
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A systems genetic analysis of high density lipoprotein metabolism and network preservation across mouse models. Biochim Biophys Acta (2011) 0.88
Polymorphisms in the hepatic lipase gene affect plasma HDL-cholesterol levels in a Turkish population. J Lipid Res (2009) 0.88
A multiethnic replication study of plasma lipoprotein levels-associated SNPs identified in recent GWAS. PLoS One (2013) 0.88
Genetic architecture of circulating lipid levels. Eur J Hum Genet (2011) 0.88
Joint linkage and association analysis with exome sequence data implicates SLC25A40 in hypertriglyceridemia. Am J Hum Genet (2013) 0.87
Association analysis of dyslipidemia-related genes in diabetic nephropathy. PLoS One (2013) 0.87
Association between the MLX interacting protein-like, BUD13 homolog and zinc finger protein 259 gene polymorphisms and serum lipid levels. Sci Rep (2014) 0.87
Application of statistical and functional methodologies for the investigation of genetic determinants of coronary heart disease biomarkers: lipoprotein lipase genotype and plasma triglycerides as an exemplar. Hum Mol Genet (2010) 0.87
Localization of multiple pleiotropic genes for lipoprotein metabolism in baboons. J Lipid Res (2009) 0.87
Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study. Cardiovasc Diabetol (2012) 0.86
Adaptive genetic variation and heart disease risk. Curr Opin Lipidol (2010) 0.86
The association of common SNPs and haplotypes in CETP gene with HDL cholesterol levels in Latvian population. PLoS One (2013) 0.86
Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study. BMC Genet (2013) 0.86
Diplotyper: diplotype-based association analysis. BMC Med Genomics (2013) 0.85
Genome-wide linkage scan for plasma high density lipoprotein cholesterol, apolipoprotein A-1 and triglyceride variation among American Indian populations: the Strong Heart Family Study. J Med Genet (2009) 0.84
Increased high-density lipoprotein cholesterol levels in mice with XX versus XY sex chromosomes. Arterioscler Thromb Vasc Biol (2015) 0.84
High prevalence of diabetes and pre-diabetes in adults with Williams syndrome. Am J Med Genet C Semin Med Genet (2010) 0.84
Linkage and association analyses identify a candidate region for apoB level on chromosome 4q32.3 in FCHL families. Hum Genet (2010) 0.84
Deep sequencing of the LRRK2 gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe. Hum Mutat (2012) 0.83
Genetics of coronary artery disease: focus on genome-wide association studies. Am J Transl Res (2009) 0.83
Evaluation of seven common lipid associated loci in a large Indian sib pair study. Lipids Health Dis (2012) 0.82
A genome-wide linkage scan identifies multiple quantitative trait loci for HDL-cholesterol levels in families with premature CAD and MI. J Lipid Res (2010) 0.81
A gene-centric association scan for Coagulation Factor VII levels in European and African Americans: the Candidate Gene Association Resource (CARe) Consortium. Hum Mol Genet (2011) 0.81
The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis. Trends Endocrinol Metab (2016) 0.81
Fatty acids intake in the Mexican population. Results of the National Nutrition Survey 2006. Nutr Metab (Lond) (2011) 0.81
Genome-wide association study of metabolic syndrome in koreans. Genomics Inform (2014) 0.81
The genetic architecture of lipoprotein subclasses in Gullah-speaking African American families enriched for type 2 diabetes: the Sea Islands Genetic African American Registry (Project SuGAR). J Lipid Res (2009) 0.81
Genetic and environmental determinants of the susceptibility of Amerindian derived populations for having hypertriglyceridemia. Metabolism (2014) 0.81
ChREBP regulates fructose-induced glucose production independently of insulin signaling. J Clin Invest (2016) 0.80
A Drosophila functional evaluation of candidates from human genome-wide association studies of type 2 diabetes and related metabolic traits identifies tissue-specific roles for dHHEX. BMC Genomics (2013) 0.80
Association between Eight Functional Polymorphisms and Haplotypes in the Cholesterol Ester Transfer Protein (CETP) Gene and Dyslipidemia in National Minority Adults in the Far West Region of China. Int J Environ Res Public Health (2015) 0.80
MLXIPL variant in individuals with low and high triglyceridemia in white population in Central Europe. Hum Genet (2008) 0.79
Association of FURIN and ZPR1 polymorphisms with metabolic syndrome. Biomed Rep (2015) 0.79
The transcription factor Cabut coordinates energy metabolism and the circadian clock in response to sugar sensing. EMBO J (2015) 0.78
VNN1 gene expression levels and the G-137T polymorphism are associated with HDL-C levels in Mexican prepubertal children. PLoS One (2012) 0.78
ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer. BMC Med Genomics (2013) 0.77
Pathway-Based Genome-Wide Association Studies for Plasma Triglycerides in Obese Females and Normal-Weight Controls. PLoS One (2015) 0.77
Genome-wide linkage and positional association analyses identify associations of novel AFF3 and NTM genes with triglycerides: the GenSalt study. J Genet Genomics (2015) 0.76
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol (2009) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Whole-genome patterns of common DNA variation in three human populations. Science (2005) 21.22
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
A common allele on chromosome 9 associated with coronary heart disease. Science (2007) 20.37
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Sentinel-node biopsy or nodal observation in melanoma. N Engl J Med (2006) 15.64
New models of collaboration in genome-wide association studies: the Genetic Association Information Network. Nat Genet (2007) 13.76
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
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Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
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Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature (2011) 7.43
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Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat Genet (2009) 6.39
9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response. Nature (2011) 6.25
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
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