D L Rothman

Author PubWeight™ 200.87‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes. N Engl J Med 1999 8.32
2 Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia 1999 8.17
3 Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy. N Engl J Med 1990 7.13
4 Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J Clin Invest 1999 6.73
5 Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest 1996 6.50
6 Energy on demand. Science 1999 3.80
7 Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study. J Clin Invest 1992 3.55
8 Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity. Proc Natl Acad Sci U S A 1998 3.17
9 Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects. N Engl J Med 1996 2.92
10 Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy. Arch Gen Psychiatry 1999 2.78
11 Determination of the rate of the glutamate/glutamine cycle in the human brain by in vivo 13C NMR. Proc Natl Acad Sci U S A 1999 2.76
12 Effect of triiodothyronine on mitochondrial energy coupling in human skeletal muscle. J Clin Invest 2001 2.68
13 Spatially localized 1H NMR spectra of metabolites in the human brain. Proc Natl Acad Sci U S A 1988 2.44
14 Analysis of macromolecule resonances in 1H NMR spectra of human brain. Magn Reson Med 1994 2.39
15 13C/31P NMR studies on the mechanism of insulin resistance in obesity. Diabetes 1998 2.21
16 In vivo 13C NMR measurements of cerebral glutamine synthesis as evidence for glutamate-glutamine cycling. Proc Natl Acad Sci U S A 1997 2.12
17 Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR. J Cereb Blood Flow Metab 1995 1.98
18 Improvements on an in vivo automatic shimming method [FASTERMAP]. Magn Reson Med 1997 1.92
19 NMR determination of the TCA cycle rate and alpha-ketoglutarate/glutamate exchange rate in rat brain. J Cereb Blood Flow Metab 1992 1.89
20 Homonuclear 1H double-resonance difference spectroscopy of the rat brain in vivo. Proc Natl Acad Sci U S A 1984 1.76
21 Mechanism by which glucose and insulin inhibit net hepatic glycogenolysis in humans. J Clin Invest 1998 1.75
22 Cerebral energetics and the glycogen shunt: neurochemical basis of functional imaging. Proc Natl Acad Sci U S A 2001 1.74
23 Increased tricarboxylic acid cycle flux in rat brain during forepaw stimulation detected with 1H[13C]NMR. Proc Natl Acad Sci U S A 1996 1.74
24 Quantitative functional imaging of the brain: towards mapping neuronal activity by BOLD fMRI. NMR Biomed 2001 1.69
25 Dynamic shim updating: a new approach towards optimized whole brain shimming. Magn Reson Med 1996 1.65
26 Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures. Neurology 2001 1.60
27 Echo-planar magnetic resonance imaging studies of frontal cortex activation during word generation in humans. Proc Natl Acad Sci U S A 1993 1.60
28 Localized 13C NMR spectroscopy in the human brain of amino acid labeling from D-[1-13C]glucose. J Neurochem 1994 1.60
29 13C NMR of intermediary metabolism: implications for systemic physiology. Annu Rev Physiol 2001 1.59
30 Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects. J Clin Invest 1996 1.58
31 Liver glycogen turnover in fed and fasted humans. Am J Physiol 1994 1.57
32 Direct assessment of liver glycogen storage by 13C nuclear magnetic resonance spectroscopy and regulation of glucose homeostasis after a mixed meal in normal subjects. J Clin Invest 1996 1.57
33 In vivo (13)C NMR measurement of neurotransmitter glutamate cycling, anaplerosis and TCA cycle flux in rat brain during. J Neurochem 2001 1.55
34 Detection of cerebral lactate in vivo during hypoxemia by 1H NMR at relatively low field strengths (1.9 T). Proc Natl Acad Sci U S A 1984 1.51
35 Validation of 13C NMR measurement of human skeletal muscle glycogen by direct biochemical assay of needle biopsy samples. Magn Reson Med 1992 1.51
36 A model for the regulation of cerebral oxygen delivery. J Appl Physiol (1985) 1998 1.49
37 Impaired net hepatic glycogen synthesis in insulin-dependent diabetic subjects during mixed meal ingestion. A 13C nuclear magnetic resonance spectroscopy study. J Clin Invest 1995 1.47
38 Direct measurement of brain glucose concentrations in humans by 13C NMR spectroscopy. Proc Natl Acad Sci U S A 1992 1.46
39 Lactate efflux and the neuroenergetic basis of brain function. NMR Biomed 2001 1.45
40 1H-Observe/13C-decouple spectroscopic measurements of lactate and glutamate in the rat brain in vivo. Proc Natl Acad Sci U S A 1985 1.44
41 Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy. Arch Gen Psychiatry 2001 1.43
42 The roles of insulin and glucagon in the regulation of hepatic glycogen synthesis and turnover in humans. J Clin Invest 1996 1.41
43 Contribution of net hepatic glycogenolysis to glucose production during the early postprandial period. Am J Physiol 1996 1.37
44 Interpreting functional imaging studies in terms of neurotransmitter cycling. Proc Natl Acad Sci U S A 1998 1.35
45 High-resolution CMR(O2) mapping in rat cortex: a multiparametric approach to calibration of BOLD image contrast at 7 Tesla. J Cereb Blood Flow Metab 2000 1.32
46 In vivo regulation of muscle glycogen synthase and the control of glycogen synthesis. Proc Natl Acad Sci U S A 1995 1.29
47 Stimulated changes in localized cerebral energy consumption under anesthesia. Proc Natl Acad Sci U S A 1999 1.29
48 Intramuscular glycogen and intramyocellular lipid utilization during prolonged exercise and recovery in man: a 13C and 1H nuclear magnetic resonance spectroscopy study. J Clin Endocrinol Metab 2000 1.27
49 Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy. Neurology 1999 1.26
50 Mechanism of liver glycogen repletion in vivo by nuclear magnetic resonance spectroscopy. J Clin Invest 1985 1.25
51 Quantitative analysis of glycogen repletion by nuclear magnetic resonance spectroscopy in the conscious rat. J Clin Invest 1987 1.25
52 Preliminary evidence of low cortical GABA levels in localized 1H-MR spectra of alcohol-dependent and hepatic encephalopathy patients. Am J Psychiatry 1999 1.25
53 13C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes mellitus. J Clin Invest 1994 1.21
54 Differentiation of glucose transport in human brain gray and white matter. J Cereb Blood Flow Metab 2001 1.21
55 Effect of dietary protein on in vivo insulin action and liver glycogen repletion. Am J Physiol 1989 1.21
56 Human muscle glycogen resynthesis after exercise: insulin-dependent and -independent phases. J Appl Physiol (1985) 1994 1.20
57 Localized 1H NMR measurement of glucose consumption in the human brain during visual stimulation. Proc Natl Acad Sci U S A 1993 1.17
58 Validation of 13C NMR measurements of liver glycogen in vivo. Magn Reson Med 1994 1.16
59 Contribution of hepatic glycogenolysis to glucose production in humans in response to a physiological increase in plasma glucagon concentration. Diabetes 1995 1.16
60 Glutamine is the major precursor for GABA synthesis in rat neocortex in vivo following acute GABA-transaminase inhibition. Brain Res 2001 1.14
61 Decrease in GABA synthesis rate in rat cortex following GABA-transaminase inhibition correlates with the decrease in GAD(67) protein. Brain Res 2001 1.13
62 NMR determination of intracerebral glucose concentration and transport kinetics in rat brain. J Cereb Blood Flow Metab 1992 1.12
63 Oxidative glucose metabolism in rat brain during single forepaw stimulation: a spatially localized 1H[13C] nuclear magnetic resonance study. J Cereb Blood Flow Metab 1997 1.12
64 Image reconstruction of sequentially sampled echo-planar data. Magn Reson Imaging 1995 1.09
65 Effects of gabapentin on brain GABA, homocarnosine, and pyrrolidinone in epilepsy patients. Epilepsia 2000 1.07
66 Detection of human muscle glycogen by natural abundance 13C NMR. Proc Natl Acad Sci U S A 1988 1.06
67 Proton MRS: GABA and glutamate. Adv Neurol 2000 1.06
68 13C NMR studies of glycogen turnover in the perfused rat liver. J Biol Chem 1988 1.04
69 Mechanism of impaired insulin-stimulated muscle glucose metabolism in subjects with insulin-dependent diabetes mellitus. J Clin Invest 1997 1.04
70 The "glycogen shunt" in exercising muscle: A role for glycogen in muscle energetics and fatigue. Proc Natl Acad Sci U S A 2001 1.03
71 The effect of gabapentin on brain gamma-aminobutyric acid in patients with epilepsy. Ann Neurol 1996 1.02
72 Intracellular pH in human skeletal muscle by 1H NMR. Proc Natl Acad Sci U S A 1988 1.02
73 In vivo chemical shift imaging of gamma-aminobutyric acid in the human brain. Magn Reson Med 1999 1.02
74 Natural-abundance 13C NMR study of glycogen repletion in human liver and muscle. Proc Natl Acad Sci U S A 1989 1.01
75 Low brain GABA level is associated with poor seizure control. Ann Neurol 1996 1.01
76 In vivo nuclear magnetic resonance studies of glutamate-gamma-aminobutyric acid-glutamine cycling in rodent and human cortex: the central role of glutamine. J Nutr 2001 1.01
77 Functional energy metabolism: in vivo 13C-NMR spectroscopy evidence for coupling of cerebral glucose consumption and glutamatergic neuronalactivity. Dev Neurosci 1998 1.00
78 Nuclear magnetic resonance imaging and spectroscopy of human brain function. Proc Natl Acad Sci U S A 1993 1.00
79 13C-NMR measurements of muscle glycogen during low-intensity exercise. J Appl Physiol (1985) 1991 1.00
80 Spectroscopic imaging of stroke in humans: histopathology correlates of spectral changes. Neurology 1992 0.99
81 Human brain gamma-aminobutyric acid levels and seizure control following initiation of vigabatrin therapy. J Neurochem 1996 0.99
82 Detection and assignment of the glucose signal in 1H NMR difference spectra of the human brain. Magn Reson Med 1992 0.98
83 1H NMR studies of glucose transport in the human brain. J Cereb Blood Flow Metab 1996 0.98
84 Correlation of lactate and pH in human skeletal muscle after exercise by 1H NMR. Magn Reson Med 1991 0.97
85 Proton spectroscopy of human stroke: assessment of transverse relaxation times and partial volume effects in single volume steam MRS. Magn Reson Imaging 1994 0.96
86 Turnover of human muscle glycogen with low-intensity exercise. Med Sci Sports Exerc 1994 0.95
87 Initial observations on effect of vigabatrin on in vivo 1H spectroscopic measurements of gamma-aminobutyric acid, glutamate, and glutamine in human brain. Epilepsia 1995 0.95
88 Linear projection method for automatic slice shimming. Magn Reson Med 1999 0.95
89 Early temporal variation of cerebral metabolites after human stroke. A proton magnetic resonance spectroscopy study. Stroke 1993 0.94
90 The rate of turnover of cortical GABA from [1-13C]glucose is reduced in rats treated with the GABA-transaminase inhibitor vigabatrin (gamma-vinyl GABA). Neurochem Res 1996 0.94
91 Direct observation of glycogen synthesis in human muscle with 13C NMR. Proc Natl Acad Sci U S A 1989 0.94
92 Spectroscopic imaging of glutamate C4 turnover in human brain. Magn Reson Med 2000 0.94
93 Measurement of beta-hydroxybutyrate in acute hyperketonemia in human brain. J Neurochem 2001 0.93
94 15N-NMR spectroscopy studies of ammonia transport and glutamine synthesis in the hyperammonemic rat brain. Dev Neurosci 1998 0.93
95 NMR studies of muscle glycogen synthesis in insulin-resistant offspring of parents with non-insulin-dependent diabetes mellitus immediately after glycogen-depleting exercise. Proc Natl Acad Sci U S A 1996 0.93
96 Carbon-13 nuclear magnetic resonance studies of myocardial glycogen metabolism in live guinea pigs. Biochemistry 1984 0.92
97 Effects of valproate and other antiepileptic drugs on brain glutamate, glutamine, and GABA in patients with refractory complex partial seizures. Seizure 1999 0.91
98 Acute effects of vigabatrin on brain GABA and homocarnosine in patients with complex partial seizures. Epilepsia 1999 0.91
99 Short echo time proton magnetic resonance spectroscopic imaging of macromolecule and metabolite signal intensities in the human brain. Magn Reson Med 1996 0.91
100 13C NMR relaxation times of hepatic glycogen in vitro and in vivo. Biochemistry 1990 0.91
101 Quantitative multi-modal functional MRI with blood oxygenation level dependent exponential decays adjusted for flow attenuated inversion recovery (BOLDED AFFAIR). Magn Reson Imaging 2000 0.90
102 Measuring human brain GABA in vivo: effects of GABA-transaminase inhibition with vigabatrin. Mol Neurobiol 1998 0.90
103 Detection of gamma-aminobutyric acid (GABA) by longitudinal scalar order difference editing. J Magn Reson 2001 0.89
104 Human brain GABA levels rise rapidly after initiation of vigabatrin therapy. Neurology 1996 0.89
105 Contribution of net hepatic glycogen synthesis to disposal of an oral glucose load in humans. Metabolism 2001 0.89
106 Cerebral metabolism in hyper- and hypocarbia: 31P and 1H nuclear magnetic resonance studies. Neurology 1985 0.89
107 The effect of controlled ascorbic acid depletion and supplementation on periodontal health. J Periodontol 1986 0.89
108 Human brain GABA levels rise after initiation of vigabatrin therapy but fail to rise further with increasing dose. Neurology 1996 0.88
109 Diagnostic laparotomy for fever or abdominal pain of unknown origin. Am J Surg 1977 0.87
110 1H NMR visibility of mammalian glycogen in solution. Proc Natl Acad Sci U S A 1990 0.87
111 Measurement of ethanol in the human brain using NMR spectroscopy. J Stud Alcohol 1990 0.87
112 Effects of vigabatrin on the GABAergic system as determined by [123I]iomazenil SPECT and GABA MRS. Epilepsia 1999 0.87
113 Unusual impaction of a primary lateral incisor. ASDC J Dent Child 1994 0.87
114 Enzymatic phosphorylation of muscle glycogen synthase: a mechanism for maintenance of metabolic homeostasis. Proc Natl Acad Sci U S A 1996 0.86
115 Vigabatrin increases human brain homocarnosine and improves seizure control. Ann Neurol 1998 0.86
116 In vivo measurement of phenylalanine in human brain by proton nuclear magnetic resonance spectroscopy. Pediatr Res 1995 0.86
117 Proton magnetic resonance spectroscopy of cerebral lactate and other metabolites in stroke patients. Stroke 1992 0.85
118 Topiramate rapidly raises brain GABA in epilepsy patients. Epilepsia 2001 0.85
119 NMR of glycogen in exercise. Proc Nutr Soc 1999 0.85
120 Surface coil localization of 31P NMR signals from orthotopic human kidney and liver. Proc Natl Acad Sci U S A 1988 0.85
121 Localized 13C NMR spectroscopy of myo-inositol in the human brain in vivo. Magn Reson Med 1992 0.83
122 Direct carbon versus proton heteronuclear editing of 2-13C ethanol in rabbit brain in vivo: a sensitivity comparison. Magn Reson Med 1990 0.82
123 1H NMR study of renal trimethylamine responses to dehydration and acute volume loading in man. Proc Natl Acad Sci U S A 1991 0.82
124 Response of lingual ascorbic acid test and salivary ascorbate levels to changes in ascorbic acid intake. J Dent Res 1986 0.81
125 In vivo carbon-edited detection with proton echo-planar spectroscopic imaging (ICED PEPSI): [3,4-(13)CH(2)]glutamate/glutamine tomography in rat brain. Magn Reson Med 1999 0.81
126 Noninvasive assessment of hepatic triglyceride content in humans with 13C nuclear magnetic resonance spectroscopy. Hepatology 1996 0.81
127 In vivo lactate and beta-hydroxybutyrate editing using a pure-phase refocusing pulse train. Magn Reson Med 1998 0.80
128 Nuclear magnetic resonance studies of muscle and applications to exercise and diabetes. Diabetes 1996 0.80
129 Flux control in the rat gastrocnemius glycogen synthesis pathway by in vivo 13C/31P NMR spectroscopy. Am J Physiol Endocrinol Metab 2001 0.80
130 Spectroscopic assessment of alterations in macromolecule and small-molecule metabolites in human brain after stroke. Stroke 2001 0.80
131 Glycogen loading alters muscle glycogen resynthesis after exercise. J Appl Physiol (1985) 2000 0.79
132 Non-invasive measurements of the cerebral steady-state glucose concentration and transport in humans by 13C nuclear magnetic resonance. Adv Exp Med Biol 1993 0.79
133 GABA changes with vigabatrin in the developing human brain. Epilepsia 1999 0.78
134 Cerebral lactate turnover after electroshock: in vivo measurements by 1H/13C magnetic resonance spectroscopy. J Cereb Blood Flow Metab 1992 0.78
135 NMR spectroscopic investigation of the recovery of energy and acid-base homeostasis in the cat brain after prolonged ischemia. J Cereb Blood Flow Metab 1989 0.77
136 Experimental vitamin C depletion and supplementation in young men. Nutrient interactions and dental health effects. Ann N Y Acad Sci 1987 0.77
137 Fast automatic adjustment of on-axis shims for high-resolution NMR. J Magn Reson 1997 0.77
138 Meeting report: transcranial magnetic stimulation and studies of human cognition. J Cogn Neurosci 2000 0.77
139 High resolution NMR studies of cerebral glucose metabolism in rats and humans. Adv Exp Med Biol 1991 0.77
140 Localized 1H NMR measurements of 2-pyrrolidinone in human brain in vivo. Magn Reson Med 1999 0.76
141 New NMR measurements in epilepsy. Measuring brain GABA in patients with complex partial seizures. Adv Neurol 1999 0.76
142 Proton NMR observation of phenylalanine and an aromatic metabolite in the rabbit brain in vivo. Pediatr Res 1990 0.75
143 Combined 1H and 31P NMR studies of the rat brain in vivo: effects of altered intracellular pH on metabolism. Ann N Y Acad Sci 1987 0.75
144 NMR-spectroscopic investigation of cerebral reanimation after prolonged ischemia. Acta Neurochir Suppl (Wien) 1993 0.75
145 Caries removal system: preliminary case reports of four pediatric dental patients. CDA J 1985 0.75
146 NMR studies of human brain function. Trends Biochem Sci 1994 0.75
147 The future direction of pediatric dentistry. CDA J 1986 0.75
148 Effects of trauma on pulmonary plasminogen activator activity. Surg Forum 1975 0.75
149 Adiabatic slice-selective excitation for surface coils. J Magn Reson 1997 0.75
150 Application of multipulse NMR to observe 13C-labeled metabolites in biological systems. Magn Reson Med 1985 0.75
151 Regulation of cerebral oxygen delivery. Adv Exp Med Biol 1999 0.75