Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes.
|
N Engl J Med
|
1999
|
8.32
|
2
|
Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.
|
Diabetologia
|
1999
|
8.17
|
3
|
Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy.
|
N Engl J Med
|
1990
|
7.13
|
4
|
Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity.
|
J Clin Invest
|
1999
|
6.73
|
5
|
Mechanism of free fatty acid-induced insulin resistance in humans.
|
J Clin Invest
|
1996
|
6.50
|
6
|
Energy on demand.
|
Science
|
1999
|
3.80
|
7
|
Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study.
|
J Clin Invest
|
1992
|
3.55
|
8
|
Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity.
|
Proc Natl Acad Sci U S A
|
1998
|
3.17
|
9
|
Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects.
|
N Engl J Med
|
1996
|
2.92
|
10
|
Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy.
|
Arch Gen Psychiatry
|
1999
|
2.78
|
11
|
Determination of the rate of the glutamate/glutamine cycle in the human brain by in vivo 13C NMR.
|
Proc Natl Acad Sci U S A
|
1999
|
2.76
|
12
|
Effect of triiodothyronine on mitochondrial energy coupling in human skeletal muscle.
|
J Clin Invest
|
2001
|
2.68
|
13
|
Spatially localized 1H NMR spectra of metabolites in the human brain.
|
Proc Natl Acad Sci U S A
|
1988
|
2.44
|
14
|
Analysis of macromolecule resonances in 1H NMR spectra of human brain.
|
Magn Reson Med
|
1994
|
2.39
|
15
|
13C/31P NMR studies on the mechanism of insulin resistance in obesity.
|
Diabetes
|
1998
|
2.21
|
16
|
In vivo 13C NMR measurements of cerebral glutamine synthesis as evidence for glutamate-glutamine cycling.
|
Proc Natl Acad Sci U S A
|
1997
|
2.12
|
17
|
Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR.
|
J Cereb Blood Flow Metab
|
1995
|
1.98
|
18
|
Improvements on an in vivo automatic shimming method [FASTERMAP].
|
Magn Reson Med
|
1997
|
1.92
|
19
|
NMR determination of the TCA cycle rate and alpha-ketoglutarate/glutamate exchange rate in rat brain.
|
J Cereb Blood Flow Metab
|
1992
|
1.89
|
20
|
Homonuclear 1H double-resonance difference spectroscopy of the rat brain in vivo.
|
Proc Natl Acad Sci U S A
|
1984
|
1.76
|
21
|
Mechanism by which glucose and insulin inhibit net hepatic glycogenolysis in humans.
|
J Clin Invest
|
1998
|
1.75
|
22
|
Cerebral energetics and the glycogen shunt: neurochemical basis of functional imaging.
|
Proc Natl Acad Sci U S A
|
2001
|
1.74
|
23
|
Increased tricarboxylic acid cycle flux in rat brain during forepaw stimulation detected with 1H[13C]NMR.
|
Proc Natl Acad Sci U S A
|
1996
|
1.74
|
24
|
Quantitative functional imaging of the brain: towards mapping neuronal activity by BOLD fMRI.
|
NMR Biomed
|
2001
|
1.69
|
25
|
Dynamic shim updating: a new approach towards optimized whole brain shimming.
|
Magn Reson Med
|
1996
|
1.65
|
26
|
Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures.
|
Neurology
|
2001
|
1.60
|
27
|
Echo-planar magnetic resonance imaging studies of frontal cortex activation during word generation in humans.
|
Proc Natl Acad Sci U S A
|
1993
|
1.60
|
28
|
Localized 13C NMR spectroscopy in the human brain of amino acid labeling from D-[1-13C]glucose.
|
J Neurochem
|
1994
|
1.60
|
29
|
13C NMR of intermediary metabolism: implications for systemic physiology.
|
Annu Rev Physiol
|
2001
|
1.59
|
30
|
Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects.
|
J Clin Invest
|
1996
|
1.58
|
31
|
Liver glycogen turnover in fed and fasted humans.
|
Am J Physiol
|
1994
|
1.57
|
32
|
Direct assessment of liver glycogen storage by 13C nuclear magnetic resonance spectroscopy and regulation of glucose homeostasis after a mixed meal in normal subjects.
|
J Clin Invest
|
1996
|
1.57
|
33
|
In vivo (13)C NMR measurement of neurotransmitter glutamate cycling, anaplerosis and TCA cycle flux in rat brain during.
|
J Neurochem
|
2001
|
1.55
|
34
|
Detection of cerebral lactate in vivo during hypoxemia by 1H NMR at relatively low field strengths (1.9 T).
|
Proc Natl Acad Sci U S A
|
1984
|
1.51
|
35
|
Validation of 13C NMR measurement of human skeletal muscle glycogen by direct biochemical assay of needle biopsy samples.
|
Magn Reson Med
|
1992
|
1.51
|
36
|
A model for the regulation of cerebral oxygen delivery.
|
J Appl Physiol (1985)
|
1998
|
1.49
|
37
|
Impaired net hepatic glycogen synthesis in insulin-dependent diabetic subjects during mixed meal ingestion. A 13C nuclear magnetic resonance spectroscopy study.
|
J Clin Invest
|
1995
|
1.47
|
38
|
Direct measurement of brain glucose concentrations in humans by 13C NMR spectroscopy.
|
Proc Natl Acad Sci U S A
|
1992
|
1.46
|
39
|
Lactate efflux and the neuroenergetic basis of brain function.
|
NMR Biomed
|
2001
|
1.45
|
40
|
1H-Observe/13C-decouple spectroscopic measurements of lactate and glutamate in the rat brain in vivo.
|
Proc Natl Acad Sci U S A
|
1985
|
1.44
|
41
|
Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy.
|
Arch Gen Psychiatry
|
2001
|
1.43
|
42
|
The roles of insulin and glucagon in the regulation of hepatic glycogen synthesis and turnover in humans.
|
J Clin Invest
|
1996
|
1.41
|
43
|
Contribution of net hepatic glycogenolysis to glucose production during the early postprandial period.
|
Am J Physiol
|
1996
|
1.37
|
44
|
Interpreting functional imaging studies in terms of neurotransmitter cycling.
|
Proc Natl Acad Sci U S A
|
1998
|
1.35
|
45
|
High-resolution CMR(O2) mapping in rat cortex: a multiparametric approach to calibration of BOLD image contrast at 7 Tesla.
|
J Cereb Blood Flow Metab
|
2000
|
1.32
|
46
|
In vivo regulation of muscle glycogen synthase and the control of glycogen synthesis.
|
Proc Natl Acad Sci U S A
|
1995
|
1.29
|
47
|
Stimulated changes in localized cerebral energy consumption under anesthesia.
|
Proc Natl Acad Sci U S A
|
1999
|
1.29
|
48
|
Intramuscular glycogen and intramyocellular lipid utilization during prolonged exercise and recovery in man: a 13C and 1H nuclear magnetic resonance spectroscopy study.
|
J Clin Endocrinol Metab
|
2000
|
1.27
|
49
|
Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy.
|
Neurology
|
1999
|
1.26
|
50
|
Mechanism of liver glycogen repletion in vivo by nuclear magnetic resonance spectroscopy.
|
J Clin Invest
|
1985
|
1.25
|
51
|
Quantitative analysis of glycogen repletion by nuclear magnetic resonance spectroscopy in the conscious rat.
|
J Clin Invest
|
1987
|
1.25
|
52
|
Preliminary evidence of low cortical GABA levels in localized 1H-MR spectra of alcohol-dependent and hepatic encephalopathy patients.
|
Am J Psychiatry
|
1999
|
1.25
|
53
|
13C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes mellitus.
|
J Clin Invest
|
1994
|
1.21
|
54
|
Differentiation of glucose transport in human brain gray and white matter.
|
J Cereb Blood Flow Metab
|
2001
|
1.21
|
55
|
Effect of dietary protein on in vivo insulin action and liver glycogen repletion.
|
Am J Physiol
|
1989
|
1.21
|
56
|
Human muscle glycogen resynthesis after exercise: insulin-dependent and -independent phases.
|
J Appl Physiol (1985)
|
1994
|
1.20
|
57
|
Localized 1H NMR measurement of glucose consumption in the human brain during visual stimulation.
|
Proc Natl Acad Sci U S A
|
1993
|
1.17
|
58
|
Validation of 13C NMR measurements of liver glycogen in vivo.
|
Magn Reson Med
|
1994
|
1.16
|
59
|
Contribution of hepatic glycogenolysis to glucose production in humans in response to a physiological increase in plasma glucagon concentration.
|
Diabetes
|
1995
|
1.16
|
60
|
Glutamine is the major precursor for GABA synthesis in rat neocortex in vivo following acute GABA-transaminase inhibition.
|
Brain Res
|
2001
|
1.14
|
61
|
Decrease in GABA synthesis rate in rat cortex following GABA-transaminase inhibition correlates with the decrease in GAD(67) protein.
|
Brain Res
|
2001
|
1.13
|
62
|
NMR determination of intracerebral glucose concentration and transport kinetics in rat brain.
|
J Cereb Blood Flow Metab
|
1992
|
1.12
|
63
|
Oxidative glucose metabolism in rat brain during single forepaw stimulation: a spatially localized 1H[13C] nuclear magnetic resonance study.
|
J Cereb Blood Flow Metab
|
1997
|
1.12
|
64
|
Image reconstruction of sequentially sampled echo-planar data.
|
Magn Reson Imaging
|
1995
|
1.09
|
65
|
Effects of gabapentin on brain GABA, homocarnosine, and pyrrolidinone in epilepsy patients.
|
Epilepsia
|
2000
|
1.07
|
66
|
Detection of human muscle glycogen by natural abundance 13C NMR.
|
Proc Natl Acad Sci U S A
|
1988
|
1.06
|
67
|
Proton MRS: GABA and glutamate.
|
Adv Neurol
|
2000
|
1.06
|
68
|
13C NMR studies of glycogen turnover in the perfused rat liver.
|
J Biol Chem
|
1988
|
1.04
|
69
|
Mechanism of impaired insulin-stimulated muscle glucose metabolism in subjects with insulin-dependent diabetes mellitus.
|
J Clin Invest
|
1997
|
1.04
|
70
|
The "glycogen shunt" in exercising muscle: A role for glycogen in muscle energetics and fatigue.
|
Proc Natl Acad Sci U S A
|
2001
|
1.03
|
71
|
The effect of gabapentin on brain gamma-aminobutyric acid in patients with epilepsy.
|
Ann Neurol
|
1996
|
1.02
|
72
|
Intracellular pH in human skeletal muscle by 1H NMR.
|
Proc Natl Acad Sci U S A
|
1988
|
1.02
|
73
|
In vivo chemical shift imaging of gamma-aminobutyric acid in the human brain.
|
Magn Reson Med
|
1999
|
1.02
|
74
|
Natural-abundance 13C NMR study of glycogen repletion in human liver and muscle.
|
Proc Natl Acad Sci U S A
|
1989
|
1.01
|
75
|
Low brain GABA level is associated with poor seizure control.
|
Ann Neurol
|
1996
|
1.01
|
76
|
In vivo nuclear magnetic resonance studies of glutamate-gamma-aminobutyric acid-glutamine cycling in rodent and human cortex: the central role of glutamine.
|
J Nutr
|
2001
|
1.01
|
77
|
Functional energy metabolism: in vivo 13C-NMR spectroscopy evidence for coupling of cerebral glucose consumption and glutamatergic neuronalactivity.
|
Dev Neurosci
|
1998
|
1.00
|
78
|
Nuclear magnetic resonance imaging and spectroscopy of human brain function.
|
Proc Natl Acad Sci U S A
|
1993
|
1.00
|
79
|
13C-NMR measurements of muscle glycogen during low-intensity exercise.
|
J Appl Physiol (1985)
|
1991
|
1.00
|
80
|
Spectroscopic imaging of stroke in humans: histopathology correlates of spectral changes.
|
Neurology
|
1992
|
0.99
|
81
|
Human brain gamma-aminobutyric acid levels and seizure control following initiation of vigabatrin therapy.
|
J Neurochem
|
1996
|
0.99
|
82
|
Detection and assignment of the glucose signal in 1H NMR difference spectra of the human brain.
|
Magn Reson Med
|
1992
|
0.98
|
83
|
1H NMR studies of glucose transport in the human brain.
|
J Cereb Blood Flow Metab
|
1996
|
0.98
|
84
|
Correlation of lactate and pH in human skeletal muscle after exercise by 1H NMR.
|
Magn Reson Med
|
1991
|
0.97
|
85
|
Proton spectroscopy of human stroke: assessment of transverse relaxation times and partial volume effects in single volume steam MRS.
|
Magn Reson Imaging
|
1994
|
0.96
|
86
|
Turnover of human muscle glycogen with low-intensity exercise.
|
Med Sci Sports Exerc
|
1994
|
0.95
|
87
|
Initial observations on effect of vigabatrin on in vivo 1H spectroscopic measurements of gamma-aminobutyric acid, glutamate, and glutamine in human brain.
|
Epilepsia
|
1995
|
0.95
|
88
|
Linear projection method for automatic slice shimming.
|
Magn Reson Med
|
1999
|
0.95
|
89
|
Early temporal variation of cerebral metabolites after human stroke. A proton magnetic resonance spectroscopy study.
|
Stroke
|
1993
|
0.94
|
90
|
The rate of turnover of cortical GABA from [1-13C]glucose is reduced in rats treated with the GABA-transaminase inhibitor vigabatrin (gamma-vinyl GABA).
|
Neurochem Res
|
1996
|
0.94
|
91
|
Direct observation of glycogen synthesis in human muscle with 13C NMR.
|
Proc Natl Acad Sci U S A
|
1989
|
0.94
|
92
|
Spectroscopic imaging of glutamate C4 turnover in human brain.
|
Magn Reson Med
|
2000
|
0.94
|
93
|
Measurement of beta-hydroxybutyrate in acute hyperketonemia in human brain.
|
J Neurochem
|
2001
|
0.93
|
94
|
15N-NMR spectroscopy studies of ammonia transport and glutamine synthesis in the hyperammonemic rat brain.
|
Dev Neurosci
|
1998
|
0.93
|
95
|
NMR studies of muscle glycogen synthesis in insulin-resistant offspring of parents with non-insulin-dependent diabetes mellitus immediately after glycogen-depleting exercise.
|
Proc Natl Acad Sci U S A
|
1996
|
0.93
|
96
|
Carbon-13 nuclear magnetic resonance studies of myocardial glycogen metabolism in live guinea pigs.
|
Biochemistry
|
1984
|
0.92
|
97
|
Effects of valproate and other antiepileptic drugs on brain glutamate, glutamine, and GABA in patients with refractory complex partial seizures.
|
Seizure
|
1999
|
0.91
|
98
|
Acute effects of vigabatrin on brain GABA and homocarnosine in patients with complex partial seizures.
|
Epilepsia
|
1999
|
0.91
|
99
|
Short echo time proton magnetic resonance spectroscopic imaging of macromolecule and metabolite signal intensities in the human brain.
|
Magn Reson Med
|
1996
|
0.91
|
100
|
13C NMR relaxation times of hepatic glycogen in vitro and in vivo.
|
Biochemistry
|
1990
|
0.91
|
101
|
Quantitative multi-modal functional MRI with blood oxygenation level dependent exponential decays adjusted for flow attenuated inversion recovery (BOLDED AFFAIR).
|
Magn Reson Imaging
|
2000
|
0.90
|
102
|
Measuring human brain GABA in vivo: effects of GABA-transaminase inhibition with vigabatrin.
|
Mol Neurobiol
|
1998
|
0.90
|
103
|
Detection of gamma-aminobutyric acid (GABA) by longitudinal scalar order difference editing.
|
J Magn Reson
|
2001
|
0.89
|
104
|
Human brain GABA levels rise rapidly after initiation of vigabatrin therapy.
|
Neurology
|
1996
|
0.89
|
105
|
Contribution of net hepatic glycogen synthesis to disposal of an oral glucose load in humans.
|
Metabolism
|
2001
|
0.89
|
106
|
Cerebral metabolism in hyper- and hypocarbia: 31P and 1H nuclear magnetic resonance studies.
|
Neurology
|
1985
|
0.89
|
107
|
The effect of controlled ascorbic acid depletion and supplementation on periodontal health.
|
J Periodontol
|
1986
|
0.89
|
108
|
Human brain GABA levels rise after initiation of vigabatrin therapy but fail to rise further with increasing dose.
|
Neurology
|
1996
|
0.88
|
109
|
Diagnostic laparotomy for fever or abdominal pain of unknown origin.
|
Am J Surg
|
1977
|
0.87
|
110
|
1H NMR visibility of mammalian glycogen in solution.
|
Proc Natl Acad Sci U S A
|
1990
|
0.87
|
111
|
Measurement of ethanol in the human brain using NMR spectroscopy.
|
J Stud Alcohol
|
1990
|
0.87
|
112
|
Effects of vigabatrin on the GABAergic system as determined by [123I]iomazenil SPECT and GABA MRS.
|
Epilepsia
|
1999
|
0.87
|
113
|
Unusual impaction of a primary lateral incisor.
|
ASDC J Dent Child
|
1994
|
0.87
|
114
|
Enzymatic phosphorylation of muscle glycogen synthase: a mechanism for maintenance of metabolic homeostasis.
|
Proc Natl Acad Sci U S A
|
1996
|
0.86
|
115
|
Vigabatrin increases human brain homocarnosine and improves seizure control.
|
Ann Neurol
|
1998
|
0.86
|
116
|
In vivo measurement of phenylalanine in human brain by proton nuclear magnetic resonance spectroscopy.
|
Pediatr Res
|
1995
|
0.86
|
117
|
Proton magnetic resonance spectroscopy of cerebral lactate and other metabolites in stroke patients.
|
Stroke
|
1992
|
0.85
|
118
|
Topiramate rapidly raises brain GABA in epilepsy patients.
|
Epilepsia
|
2001
|
0.85
|
119
|
NMR of glycogen in exercise.
|
Proc Nutr Soc
|
1999
|
0.85
|
120
|
Surface coil localization of 31P NMR signals from orthotopic human kidney and liver.
|
Proc Natl Acad Sci U S A
|
1988
|
0.85
|
121
|
Localized 13C NMR spectroscopy of myo-inositol in the human brain in vivo.
|
Magn Reson Med
|
1992
|
0.83
|
122
|
Direct carbon versus proton heteronuclear editing of 2-13C ethanol in rabbit brain in vivo: a sensitivity comparison.
|
Magn Reson Med
|
1990
|
0.82
|
123
|
1H NMR study of renal trimethylamine responses to dehydration and acute volume loading in man.
|
Proc Natl Acad Sci U S A
|
1991
|
0.82
|
124
|
Response of lingual ascorbic acid test and salivary ascorbate levels to changes in ascorbic acid intake.
|
J Dent Res
|
1986
|
0.81
|
125
|
In vivo carbon-edited detection with proton echo-planar spectroscopic imaging (ICED PEPSI): [3,4-(13)CH(2)]glutamate/glutamine tomography in rat brain.
|
Magn Reson Med
|
1999
|
0.81
|
126
|
Noninvasive assessment of hepatic triglyceride content in humans with 13C nuclear magnetic resonance spectroscopy.
|
Hepatology
|
1996
|
0.81
|
127
|
In vivo lactate and beta-hydroxybutyrate editing using a pure-phase refocusing pulse train.
|
Magn Reson Med
|
1998
|
0.80
|
128
|
Nuclear magnetic resonance studies of muscle and applications to exercise and diabetes.
|
Diabetes
|
1996
|
0.80
|
129
|
Flux control in the rat gastrocnemius glycogen synthesis pathway by in vivo 13C/31P NMR spectroscopy.
|
Am J Physiol Endocrinol Metab
|
2001
|
0.80
|
130
|
Spectroscopic assessment of alterations in macromolecule and small-molecule metabolites in human brain after stroke.
|
Stroke
|
2001
|
0.80
|
131
|
Glycogen loading alters muscle glycogen resynthesis after exercise.
|
J Appl Physiol (1985)
|
2000
|
0.79
|
132
|
Non-invasive measurements of the cerebral steady-state glucose concentration and transport in humans by 13C nuclear magnetic resonance.
|
Adv Exp Med Biol
|
1993
|
0.79
|
133
|
GABA changes with vigabatrin in the developing human brain.
|
Epilepsia
|
1999
|
0.78
|
134
|
Cerebral lactate turnover after electroshock: in vivo measurements by 1H/13C magnetic resonance spectroscopy.
|
J Cereb Blood Flow Metab
|
1992
|
0.78
|
135
|
NMR spectroscopic investigation of the recovery of energy and acid-base homeostasis in the cat brain after prolonged ischemia.
|
J Cereb Blood Flow Metab
|
1989
|
0.77
|
136
|
Experimental vitamin C depletion and supplementation in young men. Nutrient interactions and dental health effects.
|
Ann N Y Acad Sci
|
1987
|
0.77
|
137
|
Fast automatic adjustment of on-axis shims for high-resolution NMR.
|
J Magn Reson
|
1997
|
0.77
|
138
|
Meeting report: transcranial magnetic stimulation and studies of human cognition.
|
J Cogn Neurosci
|
2000
|
0.77
|
139
|
High resolution NMR studies of cerebral glucose metabolism in rats and humans.
|
Adv Exp Med Biol
|
1991
|
0.77
|
140
|
Localized 1H NMR measurements of 2-pyrrolidinone in human brain in vivo.
|
Magn Reson Med
|
1999
|
0.76
|
141
|
New NMR measurements in epilepsy. Measuring brain GABA in patients with complex partial seizures.
|
Adv Neurol
|
1999
|
0.76
|
142
|
Proton NMR observation of phenylalanine and an aromatic metabolite in the rabbit brain in vivo.
|
Pediatr Res
|
1990
|
0.75
|
143
|
Combined 1H and 31P NMR studies of the rat brain in vivo: effects of altered intracellular pH on metabolism.
|
Ann N Y Acad Sci
|
1987
|
0.75
|
144
|
NMR-spectroscopic investigation of cerebral reanimation after prolonged ischemia.
|
Acta Neurochir Suppl (Wien)
|
1993
|
0.75
|
145
|
Caries removal system: preliminary case reports of four pediatric dental patients.
|
CDA J
|
1985
|
0.75
|
146
|
NMR studies of human brain function.
|
Trends Biochem Sci
|
1994
|
0.75
|
147
|
The future direction of pediatric dentistry.
|
CDA J
|
1986
|
0.75
|
148
|
Effects of trauma on pulmonary plasminogen activator activity.
|
Surg Forum
|
1975
|
0.75
|
149
|
Adiabatic slice-selective excitation for surface coils.
|
J Magn Reson
|
1997
|
0.75
|
150
|
Application of multipulse NMR to observe 13C-labeled metabolites in biological systems.
|
Magn Reson Med
|
1985
|
0.75
|
151
|
Regulation of cerebral oxygen delivery.
|
Adv Exp Med Biol
|
1999
|
0.75
|