Published in Mol Cell Neurosci on February 01, 2005
The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron (2006) 4.12
Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLoS Biol (2013) 2.61
Mitochondrial CB₁ receptors regulate neuronal energy metabolism. Nat Neurosci (2012) 2.15
Treatment of human disease by adeno-associated viral gene transfer. Hum Genet (2006) 1.84
The Homer family proteins. Genome Biol (2007) 1.78
Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities. Nat Neurosci (2012) 1.66
Parvalbumin interneurons provide grid cell-driven recurrent inhibition in the medial entorhinal cortex. Nat Neurosci (2014) 1.66
Dimensions of a projection column and architecture of VPM and POm axons in rat vibrissal cortex. Cereb Cortex (2010) 1.62
Arc regulates spine morphology and maintains network stability in vivo. Proc Natl Acad Sci U S A (2010) 1.51
Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: functional implications for alcoholism. J Neurosci (2009) 1.47
Homers regulate drug-induced neuroplasticity: implications for addiction. Biochem Pharmacol (2007) 1.43
Production and titering of recombinant adeno-associated viral vectors. J Vis Exp (2011) 1.41
Nerve terminal nicotinic acetylcholine receptors initiate quantal GABA release from perisomatic interneurons by activating axonal T-type (Cav3) Ca²⁺ channels and Ca²⁺ release from stores. J Neurosci (2011) 1.10
Accumbens Homer2-mediated signaling: a factor contributing to mouse strain differences in alcohol drinking? Genes Brain Behav (2010) 1.09
CNS-targeted viral delivery of G-CSF in an animal model for ALS: improved efficacy and preservation of the neuromuscular unit. Mol Ther (2010) 1.08
Successful cognitive aging in rats: a role for mGluR5 glutamate receptors, homer 1 proteins and downstream signaling pathways. PLoS One (2012) 1.07
Adeno-associated virus-mediated expression and constitutive secretion of NPY or NPY13-36 suppresses seizure activity in vivo. Gene Ther (2007) 1.05
Anti-Abeta single-chain antibody delivery via adeno-associated virus for treatment of Alzheimer's disease. Neurobiol Dis (2006) 1.04
Homer 1a gates the induction mechanism for endocannabinoid-mediated synaptic plasticity. J Neurosci (2010) 1.04
Select overexpression of homer1a in dorsal hippocampus impairs spatial working memory. Front Neurosci (2007) 1.00
Glial promoter selectivity following AAV-delivery to the immature brain. PLoS One (2013) 1.00
Requirement of the immediate early gene vesl-1S/homer-1a for fear memory formation. Mol Brain (2009) 0.99
Regulation of motor performance and striatal function by synaptic scaffolding proteins of the Homer1 family. Proc Natl Acad Sci U S A (2006) 0.99
Imaging synaptic inhibition throughout the brain via genetically targeted Clomeleon. Brain Cell Biol (2008) 0.99
Optogenetic release of ACh induces rhythmic bursts of perisomatic IPSCs in hippocampus. PLoS One (2011) 0.99
AAV vector-mediated overexpression of CB1 cannabinoid receptor in pyramidal neurons of the hippocampus protects against seizure-induced excitoxicity. PLoS One (2010) 0.98
Rescue of synaptic plasticity and spatial learning deficits in the hippocampus of Homer1 knockout mice by recombinant Adeno-associated viral gene delivery of Homer1c. Neurobiol Learn Mem (2011) 0.97
KIBRA (KIdney/BRAin protein) regulates learning and memory and stabilizes Protein kinase Mζ. J Neurochem (2013) 0.95
Imbalances in prefrontal cortex CC-Homer1 versus CC-Homer2 expression promote cocaine preference. J Neurosci (2013) 0.94
Wakefulness Is Governed by GABA and Histamine Cotransmission. Neuron (2015) 0.89
Gene delivery of Homer1c rescues spatial learning in a rodent model of cognitive aging. Neurobiol Aging (2013) 0.88
Gene therapy in epilepsy. Epilepsia (2008) 0.87
Neuronal ensembles sufficient for recovery sleep and the sedative actions of α2 adrenergic agonists. Nat Neurosci (2015) 0.86
Cocaine activates Homer1 immediate early gene transcription in the mesocorticolimbic circuit: differential regulation by dopamine and glutamate signaling. Synapse (2009) 0.86
Adeno-associated virus (AAV)-mediated suppression of Ca2+/calmodulin kinase IV activity in the nucleus accumbens modulates emotional behaviour in mice. BMC Neurosci (2007) 0.86
AAV-Mediated Overexpression of the CB1 Receptor in the mPFC of Adult Rats Alters Cognitive Flexibility, Social Behavior, and Emotional Reactivity. Front Behav Neurosci (2011) 0.86
Photooxidation-guided ultrastructural identification and analysis of cells in neuronal tissue labeled with green fluorescent protein. PLoS One (2013) 0.85
Group 1 metabotropic glutamate receptor function and its regulation of learning and memory in the aging brain. Front Pharmacol (2012) 0.85
A novel, rapidly acquired and persistent spatial memory task that induces immediate early gene expression. Behav Brain Funct (2010) 0.84
Enhanced expression of Pctk1, Tcf12 and Ccnd1 in hippocampus of rats: Impact on cognitive function, synaptic plasticity and pathology. Neurobiol Learn Mem (2011) 0.84
FGF22 signaling regulates synapse formation during post-injury remodeling of the spinal cord. EMBO J (2015) 0.83
Cocaine-elicited imbalances in ventromedial prefrontal cortex Homer1 versus Homer2 expression: implications for relapse. Addict Biol (2013) 0.82
Controlled and localized genetic manipulation in the brain. J Cell Mol Med (2006) 0.81
Increasing levels of wild-type CREB up-regulates several activity-regulated inhibitor of death (AID) genes and promotes neuronal survival. BMC Neurosci (2012) 0.81
Selective reduction of AMPA currents onto hippocampal interneurons impairs network oscillatory activity. PLoS One (2012) 0.81
Homer-1a immediate early gene expression correlates with better cognitive performance in aging. Age (Dordr) (2012) 0.81
Recombinant Human Myelin-Associated Glycoprotein Promoter Drives Selective AAV-Mediated Transgene Expression in Oligodendrocytes. Front Mol Neurosci (2016) 0.79
Homers at the Interface between Reward and Pain. Front Psychiatry (2013) 0.79
The nuclear calcium signaling target, activating transcription factor 3 (ATF3), protects against dendrotoxicity and facilitates the recovery of synaptic transmission after an excitotoxic insult. J Biol Chem (2014) 0.78
Epileptic stimulus increases Homer 1a expression to modulate endocannabinoid signaling in cultured hippocampal neurons. Neuropharmacology (2012) 0.78
RANGE: Gene Transfer of Reversibly Controlled Polycistronic Genes. Mol Ther Nucleic Acids (2013) 0.78
Mitochondrial redox and pH signaling occurs in axonal and synaptic organelle clusters. Sci Rep (2016) 0.78
Semaphorin 6A improves functional recovery in conjunction with motor training after cerebral ischemia. PLoS One (2010) 0.78
Differential up-regulation of Vesl-1/Homer 1 protein isoforms associated with decline in visual performance in a preclinical glaucoma model. Vision Res (2013) 0.77
Homer2 within the nucleus accumbens core bidirectionally regulates alcohol intake by both P and Wistar rats. Alcohol (2015) 0.77
Cocaine-Induced Synaptic Alterations in Thalamus to Nucleus Accumbens Projection. Neuropsychopharmacology (2016) 0.76
Glutamatergic signaling and low prodynorphin expression are associated with intact memory and reduced anxiety in rat models of healthy aging. Front Aging Neurosci (2014) 0.76
AAV-mediated overexpression of neuroserpin in the hippocampus decreases PSD-95 expression but does not affect hippocampal-dependent learning and memory. PLoS One (2014) 0.76
Overexpression of synapsin Ia in the rat calyx of Held accelerates short-term plasticity and decreases synaptic vesicle volume and active zone area. Front Cell Neurosci (2013) 0.75
Bottom-Up versus Top-Down Induction of Sleep by Zolpidem Acting on Histaminergic and Neocortex Neurons. J Neurosci (2016) 0.75
Heterotopic Transcallosal Projections Are Present throughout the Mouse Cortex. Front Cell Neurosci (2017) 0.75
Hippocampal Homer1 levels influence motivational behavior in an operant conditioning task. PLoS One (2014) 0.75
Nuclear Calcium Buffering Capacity Shapes Neuronal Architecture. J Biol Chem (2015) 0.75
Homer1a protein expression in schizophrenia, bipolar disorder, and major depression. J Neural Transm (Vienna) (2017) 0.75
Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial. Lancet (2007) 7.01
AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial. Lancet Neurol (2011) 4.23
Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach. Neuron (2009) 4.18
Environmental and genetic activation of a brain-adipocyte BDNF/leptin axis causes cancer remission and inhibition. Cell (2010) 3.71
VEGF links hippocampal activity with neurogenesis, learning and memory. Nat Genet (2004) 3.60
White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis. Cell Metab (2011) 2.68
Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1. Nat Med (2007) 2.20
Modulation of metabolic brain networks after subthalamic gene therapy for Parkinson's disease. Proc Natl Acad Sci U S A (2007) 1.98
Homer proteins regulate sensitivity to cocaine. Neuron (2004) 1.83
Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo. Neuron (2011) 1.78
Anticonvulsant and antiepileptogenic effects mediated by adeno-associated virus vector neuropeptide Y expression in the rat hippocampus. J Neurosci (2004) 1.66
Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates. Mol Ther (2009) 1.66
The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage. Proc Natl Acad Sci U S A (2007) 1.57
NMDA receptors inhibit synapse unsilencing during brain development. Proc Natl Acad Sci U S A (2008) 1.52
Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease. Proc Natl Acad Sci U S A (2006) 1.51
Striking differences in glucose and lactate levels between brain extracellular fluid and plasma in conscious human subjects: effects of hyperglycemia and hypoglycemia. J Cereb Blood Flow Metab (2002) 1.48
Promoters and regulatory elements that improve adeno-associated virus transgene expression in the brain. Methods (2002) 1.42
Gene therapy for spinal cord injury and disease. J Spinal Cord Med (2002) 1.41
Subthalamic GAD gene therapy in a Parkinson's disease rat model. Science (2002) 1.40
Neuropeptide Y gene therapy decreases chronic spontaneous seizures in a rat model of temporal lobe epilepsy. Brain (2008) 1.36
Synaptic scaffolding protein Homer1a protects against chronic inflammatory pain. Nat Med (2006) 1.35
Role of noradrenergic signaling by the nucleus tractus solitarius in mediating opiate reward. Science (2006) 1.35
Recombinant AAV-mediated expression of galanin in rat hippocampus suppresses seizure development. Eur J Neurosci (2003) 1.32
AAV vector-mediated RNAi of mutant huntingtin expression is neuroprotective in a novel genetic rat model of Huntington's disease. Mol Ther (2008) 1.31
Immunological aspects of recombinant adeno-associated virus delivery to the mammalian brain. J Virol (2002) 1.30
Early life stress alters adult serotonin 2C receptor pre-mRNA editing and expression of the alpha subunit of the heterotrimeric G-protein G q. J Neurosci (2007) 1.29
Molecular therapy of obesity and diabetes by a physiological autoregulatory approach. Nat Med (2009) 1.28
Subthalamic glutamic acid decarboxylase gene therapy: changes in motor function and cortical metabolism. J Cereb Blood Flow Metab (2006) 1.26
Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo. Proc Natl Acad Sci U S A (2005) 1.26
Brain uptake of the glucagon-like peptide-1 antagonist exendin(9-39) after intranasal administration. J Pharmacol Exp Ther (2004) 1.23
Development and optimization of adeno-associated virus vector transfer into the central nervous system. Methods Mol Med (2003) 1.23
Long-term follow-up after gene therapy for canavan disease. Sci Transl Med (2012) 1.22
IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice. J Clin Invest (2008) 1.17
AAV-mediated gene delivery of BDNF or GDNF is neuroprotective in a model of Huntington disease. Mol Ther (2004) 1.16
Novel role of Y1 receptors in the coordinated regulation of bone and energy homeostasis. J Biol Chem (2007) 1.14
Antiapoptotic and trophic effects of dominant-negative forms of dual leucine zipper kinase in dopamine neurons of the substantia nigra in vivo. J Neurosci (2008) 1.12
In vitro potency, pharmacokinetic profiles, and pharmacological activity of optimized anti-IL-21R antibodies in a mouse model of lupus. MAbs (2010) 1.09
Restoration of aspartoacylase activity in CNS neurons does not ameliorate motor deficits and demyelination in a model of Canavan disease. Mol Ther (2005) 1.08
Distinct roles for different Homer1 isoforms in behaviors and associated prefrontal cortex function. J Neurosci (2005) 1.08
Regression of upper gastric cancer in mice by FHIT gene delivery. FASEB J (2003) 1.06
Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Abeta levels. Mol Neurodegener (2007) 1.06
IL-21 receptor is critical for the development of memory B cell responses. J Immunol (2010) 1.05
What is the brain-cancer connection? Annu Rev Neurosci (2012) 1.04
Viral restoration of dopamine to the nucleus accumbens is sufficient to induce a locomotor response to amphetamine. Brain Res (2003) 1.04
Somatic gene transfer of cAMP response element-binding protein attenuates memory impairment in aging rats. Proc Natl Acad Sci U S A (2006) 1.03
ATF3 enhances c-Jun-mediated neurite sprouting. Brain Res Mol Brain Res (2003) 1.03
IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice. J Immunol (2012) 1.02
Recombinant adeno-associated virus serotypes 2- and 5-mediated gene transfer in the mammalian brain: quantitative analysis of heparin co-infusion. Mol Ther (2002) 1.02
Restoration of receptor-type protein tyrosine phosphatase eta function inhibits human pancreatic carcinoma cell growth in vitro and in vivo. Carcinogenesis (2004) 1.00
Local dopamine production in the dorsal striatum restores goal-directed behavior in dopamine-deficient mice. Behav Neurosci (2006) 0.97
Differential actions of NPY on seizure modulation via Y1 and Y2 receptors: evidence from receptor knockout mice. Epilepsia (2006) 0.97
A novel role of circadian transcription factor DBP in hippocampal plasticity. Mol Cell Neurosci (2005) 0.97
Structural and functional neuroprotection in a rat model of Huntington's disease by viral gene transfer of GDNF. Exp Neurol (2003) 0.94
Disulfiram facilitates the development and expression of locomotor sensitization to cocaine in rats. Biol Psychiatry (2003) 0.93
IL-21 is an antitolerogenic cytokine of the late-phase alloimmune response. Diabetes (2011) 0.92
Identification and distribution of aspartoacylase in the postnatal rat brain. Neuroreport (2003) 0.92
Paradoxical facilitatory effect of low-dose alcohol consumption on memory mediated by NMDA receptors. J Neurosci (2007) 0.92
Over expression of ATF-3 protects rat hippocampal neurons from in vivo injection of kainic acid. Brain Res Mol Brain Res (2004) 0.92
Screening the yeast deletant mutant collection for hypersensitivity and hyper-resistance to sorbate, a weak organic acid food preservative. Yeast (2004) 0.92
Essential role of cytoplasmic cdk5 and Prx2 in multiple ischemic injury models, in vivo. J Neurosci (2009) 0.91
Molecular investigation of TBP allele length: a SCA17 cellular model and population study. Neurobiol Dis (2003) 0.90
Correlation of pharmacodynamic activity, pharmacokinetics, and anti-product antibody responses to anti-IL-21R antibody therapeutics following IV administration to cynomolgus monkeys. J Transl Med (2010) 0.90
Localized disruption of Narp in medial prefrontal cortex blocks reinforcer devaluation performance. Learn Mem (2010) 0.90
Assessment of tropism and effectiveness of new primate-derived hybrid recombinant AAV serotypes in the mouse and primate retina. PLoS One (2013) 0.90
Network modulation following sham surgery in Parkinson's disease. J Clin Invest (2014) 0.89
Dysregulation of striatal dopamine signaling by amphetamine inhibits feeding by hungry mice. Neuron (2004) 0.89
Combined deletion of Y1, Y2, and Y4 receptors prevents hypothalamic neuropeptide Y overexpression-induced hyperinsulinemia despite persistence of hyperphagia and obesity. Endocrinology (2006) 0.88
NPY gene transfer in the hippocampus attenuates synaptic plasticity and learning. Hippocampus (2008) 0.88
Viral mediated neuropeptide Y expression in the rat paraventricular nucleus results in obesity. Obesity (Silver Spring) (2007) 0.87
Interleukin-21 receptor deficiency increases the initial toll-like receptor 2 response but protects against joint pathology by reducing Th1 and Th17 cells during streptococcal cell wall arthritis. Arthritis Rheumatol (2014) 0.87
Adult-onset hippocampal-specific neuropeptide Y overexpression confers mild anxiolytic effect in mice. Eur Neuropsychopharmacol (2009) 0.87
Gene therapy in epilepsy. Epilepsia (2008) 0.87
A role for dopamine in feeding responses produced by orexigenic agents. Brain Res (2004) 0.86
Stroke patients develop antibodies that react with components of N-methyl-D-aspartate receptor subunit 1 in proportion to lesion size. Stroke (2013) 0.86
Regulation of the postnatal development of dopamine neurons of the substantia nigra in vivo by Akt/protein kinase B. J Neurochem (2009) 0.86
Hippocampal NPY gene transfer attenuates seizures without affecting epilepsy-induced impairment of LTP. Exp Neurol (2008) 0.86