J L Madara

Author PubWeight™ 198.41‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J Immunol 2001 6.62
2 Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination. Science 2000 5.38
3 Salmonella typhimurium attachment to human intestinal epithelial monolayers: transcellular signalling to subepithelial neutrophils. J Cell Biol 1993 4.62
4 Occluding junction structure-function relationships in a cultured epithelial monolayer. J Cell Biol 1985 4.21
5 Neutrophil migration across a cultured intestinal epithelium. Dependence on a CD11b/CD18-mediated event and enhanced efficiency in physiological direction. J Clin Invest 1991 3.67
6 Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers. J Clin Invest 1988 3.12
7 Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation. Am J Physiol 1997 3.07
8 Structural analysis of a human intestinal epithelial cell line. Gastroenterology 1987 2.80
9 Design of lipoxin A4 stable analogs that block transmigration and adhesion of human neutrophils. Biochemistry 1995 2.75
10 Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia. Proc Natl Acad Sci U S A 1995 2.70
11 Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response. J Clin Invest 2001 2.67
12 Intestinal absorptive cell tight junctions are linked to cytoskeleton. Am J Physiol 1987 2.58
13 Effects of polymorphonuclear leukocyte transmigration on the barrier function of cultured intestinal epithelial monolayers. J Clin Invest 1987 2.56
14 Tight junctions are membrane microdomains. J Cell Sci 2000 2.55
15 Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivity. J Cell Biol 1986 2.53
16 Surface attachment of Salmonella typhimurium to intestinal epithelia imprints the subepithelial matrix with gradients chemotactic for neutrophils. J Cell Biol 1995 2.53
17 Established intestinal cell lines as model systems for electrolyte transport studies. Methods Enzymol 1990 2.48
18 Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells. Am J Physiol Gastrointest Liver Physiol 2000 2.48
19 Transepithelial signaling to neutrophils by salmonellae: a novel virulence mechanism for gastroenteritis. Infect Immun 1995 2.35
20 Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers. J Clin Invest 1993 2.15
21 Apical secretion of a pathogen-elicited epithelial chemoattractant activity in response to surface colonization of intestinal epithelia by Salmonella typhimurium. J Immunol 1998 2.06
22 Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells. J Immunol 1993 2.05
23 Mechanism of cholera toxin action on a polarized human intestinal epithelial cell line: role of vesicular traffic. J Cell Biol 1992 2.00
24 Neutrophil migration across cultured intestinal epithelial monolayers is modulated by epithelial exposure to IFN-gamma in a highly polarized fashion. J Cell Biol 1993 1.96
25 Ganglioside structure dictates signal transduction by cholera toxin and association with caveolae-like membrane domains in polarized epithelia. J Cell Biol 1998 1.90
26 Neutrophil migration across a cultured epithelial monolayer elicits a biphasic resistance response representing sequential effects on transcellular and paracellular pathways. J Cell Biol 1992 1.89
27 Intestinal epithelial restitution. Characterization of a cell culture model and mapping of cytoskeletal elements in migrating cells. J Clin Invest 1992 1.88
28 Targeting of cholera toxin and Escherichia coli heat labile toxin in polarized epithelia: role of COOH-terminal KDEL. J Cell Biol 1995 1.86
29 Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins. Infect Immun 2001 1.85
30 The A2b adenosine receptor mediates cAMP responses to adenosine receptor agonists in human intestinal epithelia. J Biol Chem 1995 1.85
31 In vitro model of intestinal crypt abscess. A novel neutrophil-derived secretagogue activity. J Clin Invest 1991 1.84
32 Partitioning of paracellular conductance along the ileal crypt-villus axis: a hypothesis based on structural analysis with detailed consideration of tight junction structure-function relationships. J Membr Biol 1984 1.82
33 CD47 mediates post-adhesive events required for neutrophil migration across polarized intestinal epithelia. J Cell Biol 1996 1.81
34 Surface expression, polarization, and functional significance of CD73 in human intestinal epithelia. J Clin Invest 1997 1.75
35 Salmonella typhimurium induces epithelial IL-8 expression via Ca(2+)-mediated activation of the NF-kappaB pathway. J Clin Invest 2000 1.74
36 Neutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6. J Clin Invest 2001 1.73
37 Intraepithelial eosinophils: a new diagnostic criterion for reflux esophagitis. Gastroenterology 1982 1.73
38 Cryptosporidium: cellular localization, structural analysis of absorptive cell-parasite membrane-membrane interactions in guinea pigs, and suggestion of protozoan transport by M cells. Gastroenterology 1986 1.70
39 Entry of cholera toxin into polarized human intestinal epithelial cells. Identification of an early brefeldin A sensitive event required for A1-peptide generation. J Clin Invest 1993 1.69
40 Clostridium difficile toxin B disrupts the barrier function of T84 monolayers. Gastroenterology 1992 1.62
41 Increases in guinea pig small intestinal transepithelial resistance induced by osmotic loads are accompanied by rapid alterations in absorptive-cell tight-junction structure. J Cell Biol 1983 1.61
42 Identification of a human enterocyte lipoxin A4 receptor that is regulated by interleukin (IL)-13 and interferon gamma and inhibits tumor necrosis factor alpha-induced IL-8 release. J Exp Med 1998 1.58
43 Pathogen-induced chemokine secretion from model intestinal epithelium is inhibited by lipoxin A4 analogs. J Clin Invest 1998 1.57
44 The role of CD47 in neutrophil transmigration. Increased rate of migration correlates with increased cell surface expression of CD47. J Biol Chem 2001 1.55
45 IL-4 directly modulates function of a model human intestinal epithelium. J Immunol 1994 1.53
46 Hepatocyte growth factor/scatter factor effects on epithelia. Regulation of intercellular junctions in transformed and nontransformed cell lines, basolateral polarization of c-met receptor in transformed and natural intestinal epithelia, and induction of rapid wound repair in a transformed model epithelium. J Clin Invest 1994 1.51
47 Stabilization of F-actin prevents cAMP-elicited Cl- secretion in T84 cells. J Clin Invest 1991 1.49
48 Transcytosis of cholera toxin subunits across model human intestinal epithelia. Proc Natl Acad Sci U S A 1995 1.46
49 Characterization of epithelial chemoattractants for human intestinal intraepithelial lymphocytes. Gastroenterology 2001 1.44
50 Orchestration of neutrophil movement by intestinal epithelial cells in response to Salmonella typhimurium can be uncoupled from bacterial internalization. Infect Immun 1999 1.40
51 Rapid barrier restitution in an in vitro model of intestinal epithelial injury. Lab Invest 1989 1.40
52 Expression and polarization of intercellular adhesion molecule-1 on human intestinal epithelia: consequences for CD11b/CD18-mediated interactions with neutrophils. Mol Med 1996 1.39
53 Interferon-gamma induces a cell surface phenotype switch on T84 intestinal epithelial cells. Am J Physiol 1994 1.38
54 C. difficile toxin A increases intestinal permeability and induces Cl- secretion. Am J Physiol 1990 1.37
55 PKC-dependent regulation of transepithelial resistance: roles of MLC and MLC kinase. Am J Physiol 1999 1.33
56 The selective and superoxide-independent disruption of intestinal epithelial tight junctions during leukocyte transmigration. Lab Invest 1988 1.32
57 Villus contraction aids repair of intestinal epithelium after injury. Am J Physiol 1989 1.30
58 Intestinal cryptosporidiosis complicated by disseminated cytomegalovirus infection. Gastroenterology 1981 1.27
59 Structural abnormalities of jejunal epithelial cell membranes in celiac sprue. Lab Invest 1980 1.26
60 Colonic epithelial hPepT1 expression occurs in inflammatory bowel disease: transport of bacterial peptides influences expression of MHC class 1 molecules. Gastroenterology 2001 1.26
61 Effects of phlorizin and sodium on glucose-elicited alterations of cell junctions in intestinal epithelia. Am J Physiol 1990 1.23
62 Interleukin-4 and interleukin-13 differentially regulate epithelial chloride secretion. J Biol Chem 1996 1.23
63 Small intestine transplantation in the rat--immunology and function. Surgery 1984 1.23
64 Assessment of inflammatory events in epithelial permeability: a rapid screening method using fluorescein dextrans. Epithelial Cell Biol 1995 1.22
65 Structure and permeability of goblet cell tight junctions in rat small intestine. J Membr Biol 1982 1.18
66 Proteolytic activation of cholera toxin and Escherichia coli labile toxin by entry into host epithelial cells. Signal transduction by a protease-resistant toxin variant. J Biol Chem 1997 1.18
67 Unmasking of intestinal epithelial lateral membrane beta1 integrin consequent to transepithelial neutrophil migration in vitro facilitates inv-mediated invasion by Yersinia pseudotuberculosis. Infect Immun 1997 1.18
68 Neutrophil migration across model intestinal epithelia: monolayer disruption and subsequent events in epithelial repair. Gastroenterology 1997 1.17
69 Intestinal epithelial restitution. Involvement of specific laminin isoforms and integrin laminin receptors in wound closure of a transformed model epithelium. Am J Pathol 1997 1.17
70 Signal transduction by cholera toxin: processing in vesicular compartments does not require acidification. Am J Physiol 1995 1.15
71 Transepithelial resistance can be regulated by the intestinal brush-border Na(+)/H(+) exchanger NHE3. Am J Physiol Cell Physiol 2000 1.14
72 Junctional complexes in fetal rat small intestine during morphogenesis. Dev Biol 1981 1.13
73 Characterization of spontaneous colitis in cotton-top tamarins (Saguinus oedipus) and its response to sulfasalazine. Gastroenterology 1985 1.11
74 Molecular cross talk between epithelial cells and pathogenic microorganisms. Cell 1991 1.11
75 Carboxy-terminal vesicular stomatitis virus G protein-tagged intestinal Na+-dependent glucose cotransporter (SGLT1): maintenance of surface expression and global transport function with selective perturbation of transport kinetics and polarized expression. J Biol Chem 1996 1.10
76 Intestinal epithelia (T84) possess basolateral ligands for CD11b/CD18-mediated neutrophil adherence. Am J Physiol 1995 1.10
77 Large intrahepatic cysts and pseudocysts. Pitfalls in diagnosis and treatment. Am J Surg 1978 1.10
78 Acute induction of human IL-8 production by intestinal epithelium triggers neutrophil infiltration without mucosal injury. Gut 2005 1.09
79 Induction of epithelial chloride secretion by channel-forming cryptdins 2 and 3. Proc Natl Acad Sci U S A 1997 1.08
80 hPepT1-mediated epithelial transport of bacteria-derived chemotactic peptides enhances neutrophil-epithelial interactions. J Clin Invest 1998 1.08
81 Metabolic aspects of small bowel transplantation in inbred rats. J Surg Res 1987 1.08
82 CD98-mediated links between amino acid transport and beta 1 integrin distribution in polarized columnar epithelia. J Biol Chem 2001 1.05
83 Interactions of neutrophils with epithelial cells: lessons from the intestine. J Am Soc Nephrol 1994 1.05
84 Na-K-2Cl cotransport in intestinal epithelial cells. Influence of chloride efflux and F-actin on regulation of cotransporter activity and bumetanide binding. J Biol Chem 1994 1.05
85 Structure and function of the intestinal epithelial barrier in health and disease. Monogr Pathol 1990 1.04
86 Structural changes in the plasma membrane accompanying differentiation of epithelial cells in human and monkey small intestine. Gastroenterology 1980 1.01
87 Structural features of the apical and tubulovesicular membranes of rodent small intestinal tuft cells. Anat Rec 1987 1.00
88 Microfilament-dependent activation of Na+/K+/2Cl- cotransport by cAMP in intestinal epithelial monolayers. J Clin Invest 1992 0.99
89 IFN-gamma modulates CD1d surface expression on intestinal epithelia. Am J Physiol 1996 0.99
90 Na:K:2Cl cotransporter (NKCC) of intestinal epithelial cells. Surface expression in response to cAMP. J Biol Chem 1996 0.99
91 Studies on role of calmodulin in Ca2+ regulation of rabbit ileal Na and Cl transport. Am J Physiol 1985 0.99
92 Intestinal epithelial cytoskeleton selectively constrains lumen-to-tissue migration of neutrophils. Am J Physiol 1996 0.97
93 Isolation of plasma membrane fractions from the intestinal epithelial model T84. Am J Physiol 1993 0.97
94 An oligopeptide permeates intestinal tight junctions at glucose-elicited dilatations. Implications for oligopeptide absorption. Gastroenterology 1991 0.97
95 Structural and functional evolution of jejunal allograft rejection in rats and the ameliorating effects of cyclosporine therapy. J Clin Invest 1985 0.96
96 Distinct Ca2+- and cAMP-dependent anion conductances in the apical membrane of polarized T84 cells. Am J Physiol 1998 0.96
97 Noninvasive in vivo analysis of human small intestinal paracellular absorption: regulation by Na+-glucose cotransport. Dig Dis Sci 2000 0.96
98 Constitutive and regulated secretion of secretory leukocyte proteinase inhibitor by human intestinal epithelial cells. Gastroenterology 2000 0.96
99 Evidence for an adenoma-carcinoma sequence in dimethylhydrazine-induced neoplasms of rat intestinal epithelium. Am J Pathol 1983 0.95
100 The myeloid leukemia cell line HL-60 produces a factor that induces chloride secretion in cultured epithelial cells. J Leukoc Biol 1992 0.95
101 Intestinal adaptation to diabetes. Altered Na-dependent nutrient absorption in streptozocin-treated chronically diabetic rats. J Clin Invest 1987 0.94
102 LXA4, aspirin-triggered 15-epi-LXA4, and their analogs selectively downregulate PMN azurophilic degranulation. Am J Physiol 1999 0.92
103 Reconstitution of cultured intestinal epithelial monolayers with a mucosal-derived T lymphocyte cell line. Modulation of epithelial phenotype dependent on lymphocyte-basolateral membrane apposition. J Clin Invest 1994 0.92
104 Receptors involved in carbohydrate binding modulate intestinal epithelial-neutrophil interactions. J Biol Chem 1995 0.92
105 Colonic mucin composition in primates. Selective alterations associated with spontaneous colitis in the cotton-top tamarin. Gastroenterology 1985 0.92
106 Production and characterization of multiple antigenic peptide antibodies to the adenosine A2b receptor. Mol Pharmacol 1995 0.92
107 Cup cells: structure and distribution of a unique class of epithelial cells in guinea pig, rabbit, and monkey small intestine. Gastroenterology 1982 0.91
108 Effect of extracellular calcium depletion on epithelial structure and function in rabbit ileum: a model for selective crypt or villus epithelial cell damage and suggestion of secretion by villus epithelial cells. Gastroenterology 1982 0.91
109 211At radiocolloid therapy: further observations and comparison with radiocolloids of 32P, 165Dy, and 90Y. Int J Radiat Oncol Biol Phys 1984 0.90
110 Phorbol ester sequentially downregulates cAMP-regulated basolateral and apical Cl- transport pathways in T84 cells. Am J Physiol 1993 0.89
111 Migration of intestinal intraepithelial lymphocytes into a polarized epithelial monolayer. Am J Physiol 1998 0.89
112 Adhesion molecules expressed on homing lymphocytes in model intestinal epithelia. Gastroenterology 2000 0.89
113 Neutrophil transepithelial migration: regulation at the apical epithelial surface by Fc-mediated events. Am J Physiol Gastrointest Liver Physiol 2001 0.88
114 Collagens facilitate epithelial migration in restitution of native guinea pig intestinal epithelium. Gastroenterology 1992 0.88
115 Na(+)-K(+)-2Cl- cotransport and Cl- secretion evoked by heat-stable enterotoxin is microfilament dependent in T84 cells. Am J Physiol 1993 0.88
116 Physiological regulation of intestinal epithelial tight junctions as a consequence of Na(+)-coupled nutrient transport. Gastroenterology 1995 0.88
117 Regulation of tight junction resistance in T84 monolayers by elevation in intracellular Ca2+: a protein kinase C effect. J Membr Biol 1996 0.87
118 Activated eosinophils evoke chloride secretion in model intestinal epithelia primarily via regulated release of 5'-AMP. J Immunol 1993 0.86
119 Sodium-glucose cotransport and epithelial permeability. Gastroenterology 1994 0.85
120 Cryptdin-3 induces novel apical conductance(s) in Cl- secretory, including cystic fibrosis, epithelia. Am J Physiol Cell Physiol 2001 0.84
121 Negative regulation of epithelium-neutrophil interactions via activation of CD44. Am J Physiol Cell Physiol 2001 0.84
122 Polarity of A2b adenosine receptor expression determines characteristics of receptor desensitization. Am J Physiol Cell Physiol 2000 0.84
123 Human eosinophils migrate across an intestinal epithelium in response to platelet-activating factor. Gastroenterology 1995 0.82
124 Structural features of and cholesterol distribution in M-cell membranes in guinea pig, rat, and mouse Peyer's patches. Gastroenterology 1984 0.80
125 Cup cells: further structural characterization of the brush border and the suggestion that they may serve as an attachment site for an unidentified bacillus in guinea pig ileum. Gastroenterology 1985 0.78
126 Analysis of absorptive cell occluding junction structure-function relationships in a state of enhanced junctional permeability. Lab Invest 1987 0.78
127 Flounder intestinal absorptive cells have abundant gap junctions and may be coupled. Am J Physiol 1984 0.78
128 Structural features of the rat small intestinal microvillus membrane in acute experimental diabetes. Dig Dis Sci 1982 0.77
129 Enterocytes adhere preferentially to collagen IV in a differentially regulated divalent cation-dependent manner. Am J Physiol 1994 0.77
130 Modulation of intercellular junctions of epithelia by scatter factor (hepatocyte growth factor). EXS 1995 0.77
131 New insights on molecular pathways utilized by salmonella species in cell binding. Front Biosci 1996 0.77
132 Failure of cyclosporine to prevent small bowel allograft rejection in pigs. J Surg Res 1985 0.76
133 Periscope, up! Monitoring microbes in the intestine. Nat Immunol 2001 0.75
134 Proceedings of the 1988 Subspecialty Conference on Gastrointestinal Pathology at the USCAP. United States and Canadian Academy of Pathology. Diagnostic nonproblems in gastrointestinal biopsy pathology. Mod Pathol 1989 0.75
135 Terminal ileum or colon? Gastroenterology 1988 0.75
136 Lipoxin-stable analogs: potential therapeutic downregulators of intestinal inflammation. Ernst Schering Res Found Workshop 2000 0.75
137 Structural correlates of intestinal tight-junction permeability. Kroc Found Ser 1984 0.75
138 Distribution of filipin-sterol complexes in villus goblet cell membranes of rat small intestine. Lab Invest 1984 0.75
139 Intranuclear inclusions of the human vas deferens. Arch Pathol Lab Med 1978 0.75
140 Gastroesophageal reflux and Barrett's esophagus in developmentally disabled patients. Am J Gastroenterol 1986 0.75
141 Age-related loss of nongoblet crypt cells parallels decreased secretion in rabbit descending colon. Am J Physiol 1988 0.75
142 Hollow visceral myopathy: a light- and electron-microscopic study. Am J Surg Pathol 1982 0.75