Published in Science on February 04, 2005
The first metazoa living in permanently anoxic conditions. BMC Biol (2010) 1.74
Ultra-deep sequencing of foraminiferal microbarcodes unveils hidden richness of early monothalamous lineages in deep-sea sediments. Proc Natl Acad Sci U S A (2011) 1.34
Trench connection. Biol Lett (2011) 0.78
New violet 3,3'-bipyridyl pigment purified from deep-sea microorganism Shewanella violacea DSS12. Extremophiles (2006) 0.76
First insights into the biodiversity and biogeography of the Southern Ocean deep sea. Nature (2007) 4.98
Exponential decline of deep-sea ecosystem functioning linked to benthic biodiversity loss. Curr Biol (2007) 4.80
Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab. Ann Rheum Dis (2007) 4.05
Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial. Arthritis Rheum (2004) 3.92
Deep-sea biodiversity in the Mediterranean Sea: the known, the unknown, and the unknowable. PLoS One (2010) 2.42
Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast. Biochem Biophys Res Commun (2005) 1.80
Biotic and human vulnerability to projected changes in ocean biogeochemistry over the 21st century. PLoS Biol (2013) 1.78
Does alendronate prevent collapse in osteonecrosis of the femoral head? Clin Orthop Relat Res (2006) 1.53
The evolution of early Foraminifera. Proc Natl Acad Sci U S A (2003) 1.46
A case of hepatitis C-associated osteosclerosis in an elderly Japanese man. Endocr J (2006) 1.45
Oxygen tension is an important mediator of the transformation of osteoblasts to osteocytes. J Bone Miner Metab (2007) 1.34
Foraminifera promote calcification by elevating their intracellular pH. Proc Natl Acad Sci U S A (2009) 1.32
Blunt thyroid trauma with acute hemorrhage and respiratory distress. J Emerg Med (2007) 1.29
Matrix extracellular phosphoglycoprotein (MEPE) is highly expressed in osteocytes in human bone. J Bone Miner Metab (2004) 1.18
Cartilage repair using an in vitro generated scaffold-free tissue-engineered construct derived from porcine synovial mesenchymal stem cells. Biomaterials (2007) 1.11
Disturbance of deep-sea environments induced by the M9.0 Tohoku Earthquake. Sci Rep (2012) 1.10
Serum adiponectin concentrations correlate with severity of rheumatoid arthritis evaluated by extent of joint destruction. Clin Rheumatol (2008) 1.09
Marine biodiversity in Japanese waters. PLoS One (2010) 1.08
Clinical impact of c-Met expression and its gene amplification in hepatocellular carcinoma. Int J Clin Oncol (2012) 1.08
Matrix extracellular phosphoglycoprotein is expressed in causative tumors of oncogenic osteomalacia. J Bone Miner Metab (2011) 1.06
Guidelines for diagnosis and management of Paget's disease of bone in Japan. J Bone Miner Metab (2006) 1.04
Imatinib mesylate inhibits osteoclastogenesis and joint destruction in rats with collagen-induced arthritis (CIA). J Bone Miner Metab (2006) 1.02
Drug free REmission/low disease activity after cessation of tocilizumab (Actemra) Monotherapy (DREAM) study. Mod Rheumatol (2014) 1.01
Response of serum carboxylated and undercarboxylated osteocalcin to alendronate monotherapy and combined therapy with vitamin K2 in postmenopausal women. J Bone Miner Metab (2008) 0.99
Characteristics of fracture and related factors in patients with rheumatoid arthritis. Mod Rheumatol (2008) 0.99
In vitro generation of a scaffold-free tissue-engineered construct (TEC) derived from human synovial mesenchymal stem cells: biological and mechanical properties and further chondrogenic potential. Tissue Eng Part A (2008) 0.97
Expression of dentin matrix protein 1 in tumors causing oncogenic osteomalacia. Mod Pathol (2004) 0.95
Vertical and temporal shifts in microbial communities in the water column and sediment of saline meromictic Lake Kaiike (Japan), as determined by a 16S rDNA-based analysis, and related to physicochemical gradients. Environ Microbiol (2004) 0.94
Adenovirus-mediated gene transfer of adiponectin reduces the severity of collagen-induced arthritis in mice. Biochem Biophys Res Commun (2008) 0.93
A new species of the genus Rimicaris (Alvinocarididae: Caridea: Decapoda) from the active hydrothermal vent field, "Kairei Field," on the Central Indian Ridge, the Indian Ocean. Zoolog Sci (2002) 0.92
Circulating endothelial cells and other angiogenesis factors in pancreatic carcinoma patients receiving gemcitabine chemotherapy. BMC Cancer (2012) 0.90
IL-6 negatively regulates osteoblast differentiation through the SHP2/MEK2 and SHP2/Akt2 pathways in vitro. J Bone Miner Metab (2014) 0.90
Heterotopic ossification in bilateral knee and hip joints after long-term sedation. J Bone Miner Metab (2005) 0.89
Does presence of a mid-ocean ridge enhance biomass and biodiversity? PLoS One (2013) 0.89
Specifically modified osteopontin in rheumatoid arthritis fibroblast-like synoviocytes supports interaction with B cells and enhances production of interleukin-6. Arthritis Rheum (2009) 0.88
Three-dimensional relationship of the glenohumeral joint in the elevated position in shoulders with multidirectional instability. J Shoulder Elbow Surg (2002) 0.88
Use of bone SPECT in the evaluation of fibrous dysplasia of the skull. Clin Nucl Med (2004) 0.88
Alendronate treatment promotes bone formation with a less anisotropic microstructure during intramembranous ossification in rats. J Bone Miner Metab (2008) 0.87
Possible effects of global environmental changes on Antarctic benthos: a synthesis across five major taxa. Ecol Evol (2012) 0.87
Biogeochemical processes in the saline meromictic Lake Kaiike, Japan: implications from molecular isotopic evidences of photosynthetic pigments. Environ Microbiol (2005) 0.86
Alternative two-step matrix application method for imaging mass spectrometry to avoid tissue shrinkage and improve ionization efficiency. J Mass Spectrom (2013) 0.86
Vitamin K2 administration is associated with decreased disease activity in patients with rheumatoid arthritis. Mod Rheumatol (2012) 0.86
Creation and characterization of Japanese standards for myocardial perfusion SPECT: database from the Japanese Society of Nuclear Medicine Working Group. Ann Nucl Med (2007) 0.85
Total ankle replacement in rheumatoid arthritis. Int Orthop (2003) 0.85
Vertical niche partitioning between cryptic sibling species of a cosmopolitan marine planktonic protist. Mol Ecol (2012) 0.85
[Denosumab as the potent therapeutic agent against Paget's disease of bone]. Clin Calcium (2011) 0.84
A convenient route to the furopyran core of dysiherbaine. Org Biomol Chem (2003) 0.84
Monoclonal antibody to parathyroid hormone-related protein induces differentiation and apoptosis of chondrosarcoma cells. Cancer Lett (2003) 0.84
Whole-body MR imaging in detecting phosphaturic mesenchymal tumor (PMT) in tumor-induced hypophosphatemic osteomalacia. Magn Reson Med Sci (2013) 0.84
Radiographic study of joint destruction patterns in the rheumatoid elbow. Clin Rheumatol (2006) 0.84
Interobserver variation in diagnosis of dementia by brain perfusion SPECT. Radiat Med (2003) 0.83
Compound-specific nitrogen isotope analysis of D-alanine, L-alanine, and valine: application of diastereomer separation to delta15N and microbial peptidoglycan studies. Anal Chem (2009) 0.83
A case report of a patient with refractory adult-onset Still's disease who was successfully treated with tocilizumab over 6 years. Mod Rheumatol (2008) 0.83
Glenoid shape in atraumatic posterior instability of the shoulder. Clin Orthop Relat Res (2002) 0.83
Hadal disturbance in the Japan Trench induced by the 2011 Tohoku-Oki earthquake. Sci Rep (2013) 0.83
Efficacy, tolerability, and safety of risedronate in Japanese patients with Paget's disease of bone. J Bone Miner Metab (2010) 0.83
Serum level of oxidative stress marker is dramatically low in patients with rheumatoid arthritis treated with tocilizumab. Rheumatol Int (2011) 0.82
High oxygen tension prolongs the survival of osteoclast precursors via macrophage colony-stimulating factor. Bone (2008) 0.82
Evaluation of ischemic heart disease on a 1.5 Tesla scanner: combined first-pass perfusion and viability study. Radiat Med (2005) 0.82
Nkx3.2-induced suppression of Runx2 is a crucial mediator of hypoxia-dependent maintenance of chondrocyte phenotypes. Biochem Biophys Res Commun (2011) 0.82
A pro-inflammatory role for A20 and ABIN family proteins in human fibroblast-like synoviocytes in rheumatoid arthritis. Immunol Lett (2011) 0.81
Hydrogen, carbon and nitrogen isotopic fractionations during chlorophyll biosynthesis in C3 higher plants. Phytochemistry (2005) 0.80
Novel sandwich ELISAs for rat DMP1: age-related decrease of circulatory DMP1 levels in male rats. Bone (2013) 0.80
Oxygen and air nanobubble water solution promote the growth of plants, fishes, and mice. PLoS One (2013) 0.80
Low bacterial diversity and high labile organic matter concentrations in the sediments of the Medee deep-sea hypersaline anoxic basin. Microbes Environ (2012) 0.80
Diagnostic features of mild cellulitis phlegmon in patients with rheumatoid arthritis treated with tocilizumab: a report of two cases. Mod Rheumatol (2011) 0.80
Celecoxib prevents juxta-articular osteopenia and growth plate destruction adjacent to inflamed joints in rats with collagen-induced arthritis. Mod Rheumatol (2007) 0.79
Nkx3.2 promotes primary chondrogenic differentiation by upregulating Col2a1 transcription. PLoS One (2012) 0.79
Treatment of juxta-articular intraosseous cystic lesions in rheumatoid arthritis patients with interconnected porous calcium hydroxyapatite ceramic. Mod Rheumatol (2009) 0.79
Hydroxyapatite augmentation for bone atrophy in total ankle replacement in rheumatoid arthritis. J Foot Ankle Surg (2006) 0.79
Radiological study of joint destruction patterns in rheumatoid flatfoot. Clin Rheumatol (2007) 0.79
Characterization of Japanese standards for myocardial sympathetic and metabolic imaging in comparison with perfusion imaging. Ann Nucl Med (2009) 0.79
A feasibility study of outpatient chemotherapy with S-1 + cisplatin in patients with advanced gastric cancer. Gastric Cancer (2012) 0.78
Value of CT thallium-201 SPECT fusion imaging over SPECT alone for detection and localization of nasopharyngeal and maxillary cancers. AJR Am J Roentgenol (2006) 0.78
Nurse-like cells from patients with rheumatoid arthritis support the survival of osteoclast precursors via macrophage colony-stimulating factor production. Arthritis Rheum (2005) 0.78
The levels of somatostatin receptors in causative tumors of oncogenic osteomalacia are insufficient for their agonist to normalize serum phosphate levels. Calcif Tissue Int (2010) 0.78
The validity of multi-center common normal database for identifying myocardial ischemia: Japanese Society of Nuclear Medicine working group database. Ann Nucl Med (2009) 0.78
Extended high circular polarization in the Orion massive star forming region: implications for the origin of homochirality in the solar system. Orig Life Evol Biosph (2010) 0.78
Biodistribution of immunoliposome labeled with Tc-99m in tumor xenografted mice. Ann Nucl Med (2009) 0.78
Computer assisted planning and custom-made surgical guide for malunited pronation deformity after first metatarsophalangeal joint arthrodesis in rheumatoid arthritis: a case report. Comput Aided Surg (2014) 0.78
Impact of medium volume and oxygen concentration in the incubator on pericellular oxygen concentration and differentiation of murine chondrogenic cell culture. In Vitro Cell Dev Biol Anim (2012) 0.78
An improved method for isolation and purification of sedimentary porphyrins by high-performance liquid chromatography for compound-specific isotopic analysis. J Chromatogr A (2006) 0.78
Bioaccumulation of mercury in a vestimentiferan worm living in Kagoshima Bay, Japan. Chemosphere (2002) 0.78
In vivo three-dimensional skeletal alignment analysis of the hindfoot valgus deformity in patients with rheumatoid arthritis. J Orthop Res (2007) 0.78
Cholangiolocellular Carcinoma of the Liver Exhibiting High F-18 FDG Uptake. Tokai J Exp Clin Med (2016) 0.78
Distribution of chloropigments in suspended particulate matter and benthic microbial mat of a meromictic lake, Lake Kaiike, Japan. Environ Microbiol (2003) 0.77
Characteristics of the fatty acid composition of a deep-sea vent gastropod, Ifremeria nautilei. Lipids (2010) 0.77
Use of virtual, interactive, musculoskeletal system (VIMS) in modeling and analysis of shoulder throwing activity. J Biomech Eng (2005) 0.77
Three-dimensional kinematics of the rheumatoid wrist after partial arthrodesis. J Bone Joint Surg Am (2009) 0.77
Retreatment efficacy and safety of tocilizumab in patients with rheumatoid arthritis in recurrence (RESTORE) study. Mod Rheumatol (2014) 0.77
Involvement of valgus hindfoot deformity in hallux valgus deformity in rheumatoid arthritis. Mod Rheumatol (2013) 0.77
Role of salivary gland scintigraphy with Tc-99m pertechnetate in determining treatment of solitary parotid gland tumors: a retrospective study. Clin Nucl Med (2007) 0.77
Analysis of radiocarpal and midcarpal motion in stable and unstable rheumatoid wrists using 3-dimensional computed tomography. J Hand Surg Am (2008) 0.76
The mode of destruction in shoulders with rheumatoid arthritis based on radiographic findings. J Shoulder Elbow Surg (2007) 0.76
Scatter correction based on an artificial neural network for 99mTc and 123I dual-isotope SPECT in myocardial and brain imaging. Ann Nucl Med (2007) 0.75
Prevalence of gastroesophageal reflux disease symptoms and related factors in patients with rheumatoid arthritis. J Clin Biochem Nutr (2013) 0.75
Radiographic study on the pattern of wrist joint destruction in rheumatoid arthritis. Clin Rheumatol (2010) 0.75
Precambrian biota: protistan origin of trace fossils? Curr Biol (2009) 0.75