Published in Circ Res on February 03, 2005
Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system. Nat Rev Mol Cell Biol (2009) 5.55
Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans. PLoS Med (2006) 3.72
Autocrine and paracrine angiopoietin 1/Tie-2 signaling promotes muscle satellite cell self-renewal. Cell Stem Cell (2009) 2.53
Signaling and functions of angiopoietin-1 in vascular protection. Circ Res (2006) 2.34
Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium. Mol Cell Biol (2009) 2.09
Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling. J Clin Invest (2012) 1.85
Angiopoietin-2 stimulates breast cancer metastasis through the alpha(5)beta(1) integrin-mediated pathway. Cancer Res (2007) 1.68
Endothelial-cardiomyocyte interactions in cardiac development and repair. Annu Rev Physiol (2006) 1.68
Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway. Cancer Res (2006) 1.55
Bench-to-bedside review: Angiopoietin signalling in critical illness - a future target? Crit Care (2009) 1.45
COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model. Proc Natl Acad Sci U S A (2006) 1.42
Molecular signature of a right heart failure program in chronic severe pulmonary hypertension. Am J Respir Cell Mol Biol (2011) 1.36
Integrin and growth factor receptor alliance in angiogenesis. Cell Biochem Biophys (2008) 1.31
Angiopoietin-2: development of inhibitors for cancer therapy. Curr Oncol Rep (2009) 1.29
Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality. Am J Physiol Lung Cell Mol Physiol (2011) 1.25
Angiopoietin-1 protects heart against ischemia/reperfusion injury through VE-cadherin dephosphorylation and myocardiac integrin-β1/ERK/caspase-9 phosphorylation cascade. Mol Med (2011) 1.05
Angiopoietin-1 induces neurite outgrowth of PC12 cells in a Tie2-independent, beta1-integrin-dependent manner. Neurosci Res (2009) 1.00
PlGF repairs myocardial ischemia through mechanisms of angiogenesis, cardioprotection and recruitment of myo-angiogenic competent marrow progenitors. PLoS One (2011) 0.99
Intra and extravascular transmembrane signalling of angiopoietin-1-Tie2 receptor in health and disease. J Cell Mol Med (2008) 0.97
Endothelial-cardiomyocyte crosstalk enhances pharmacological cardioprotection. J Mol Cell Cardiol (2011) 0.96
Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy. FASEB J (2008) 0.96
Genome-wide association study identifies Loci and candidate genes for body composition and meat quality traits in Beijing-You chickens. PLoS One (2013) 0.96
Association of serum angiopoietin-1, angiopoietin-2 and angiopoietin-2 to angiopoietin-1 ratio with heart failure in patients with acute myocardial infarction. Exp Ther Med (2013) 0.86
The angiopoietin-Tie2 signaling axis in the vascular leakage of systemic inflammation. Tissue Barriers (2015) 0.85
Expression and functional roles of angiopoietin-2 in skeletal muscles. PLoS One (2011) 0.85
Primary monocytes regulate endothelial cell survival through secretion of angiopoietin-1 and activation of endothelial Tie2. Arterioscler Thromb Vasc Biol (2011) 0.84
Vascular disruption and the role of angiogenic proteins after spinal cord injury. Transl Stroke Res (2011) 0.84
Association of Ang-2 with integrin beta 2 controls Ang-2/PDGF-BB-dependent upregulation of human peripheral blood monocyte fibrinolysis. Inflammation (2009) 0.83
Molecular basis of cardioprotective effect of antioxidant vitamins in myocardial infarction. Biomed Res Int (2013) 0.82
Angiopoietins Modulate Survival, Migration, and the Components of the Ang-Tie2 Pathway of Chronic Lymphocytic Leukaemia (CLL) Cells In Vitro. Cancer Microenviron (2016) 0.82
Muscle cell derived angiopoietin-1 contributes to both myogenesis and angiogenesis in the ischemic environment. Front Physiol (2015) 0.82
Angiopoietin-1 enhances skeletal muscle regeneration in mice. Am J Physiol Regul Integr Comp Physiol (2015) 0.81
Prevention of postoperative atrial fibrillation: novel and safe strategy based on the modulation of the antioxidant system. Front Physiol (2012) 0.81
Role of angiopoietin/tie2 in critical illness: promising biomarker, disease mediator, and therapeutic target? Scientifica (Cairo) (2012) 0.81
Gene control of tyrosine kinase TIE2 and vascular manifestations of infections. Proc Natl Acad Sci U S A (2016) 0.80
QHREDGS enhances tube formation, metabolism and survival of endothelial cells in collagen-chitosan hydrogels. PLoS One (2013) 0.80
Overexpression of angiopoietin-1 reduces doxorubicin-induced apoptosis in cardiomyocytes. J Biomed Res (2012) 0.79
Integrin-mediated cell-matrix interaction in physiological and pathological blood vessel formation. J Oncol (2011) 0.79
Inhibition of apoptosis in human induced pluripotent stem cells during expansion in a defined culture using angiopoietin-1 derived peptide QHREDGS. Biomaterials (2014) 0.78
Differentiation of human CD14+ monocytes: an experimental investigation of the optimal culture medium and evidence of a lack of differentiation along the endothelial line. Exp Mol Med (2016) 0.77
Mesenchymal stem cells modified with angiopoietin-1 gene promote wound healing. Stem Cell Res Ther (2013) 0.77
Angiopoietin-1 peptide QHREDGS promotes osteoblast differentiation, bone matrix deposition and mineralization on biomedical materials. Biomater Sci (2014) 0.77
Angiopoietin1 inhibits mast cell activation and protects against anaphylaxis. PLoS One (2014) 0.77
Effects of angiopoietin-1 on attachment and metastasis of human gastric cancer cell line BGC-823. World J Gastroenterol (2009) 0.76
Proinflammatory stem cell signaling in cardiac ischemia. Antioxid Redox Signal (2009) 0.76
COMP-angiopoietin1 potentiates the effects of bone morphogenic protein-2 on ischemic necrosis of the femoral head in rats. PLoS One (2014) 0.75
Angiopoietin-1 improves endothelial progenitor cell-dependent neovascularization in diabetic wounds. Surgery (2015) 0.75
Diabetic wound regeneration using peptide-modified hydrogels to target re-epithelialization. Proc Natl Acad Sci U S A (2016) 0.75
Angiopoietin 2 signaling plays a critical role in neural crest cell migration. BMC Biol (2016) 0.75
Vasculotide, an Angiopoietin-1 mimetic, ameliorates several features of experimental atopic dermatitis-like disease. BMC Res Notes (2016) 0.75
A focus on extracellular Ca(2+) entry into skeletal muscle. Exp Mol Med (2017) 0.75
Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib. Lancet (2007) 6.76
Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med (2011) 3.80
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle like cells and form vascular networks in vivo. Circ Res (2007) 2.12
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. Nat Genet (2011) 2.10
A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Hum Mol Genet (2011) 1.98
A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study. J Allergy Clin Immunol (2011) 1.65
Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans. J Allergy Clin Immunol (2012) 1.54
Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma. Am J Respir Cell Mol Biol (2010) 1.39
Statins and pulmonary fibrosis: the potential role of NLRP3 inflammasome activation. Am J Respir Crit Care Med (2012) 1.27
Analyses of shared genetic factors between asthma and obesity in children. J Allergy Clin Immunol (2010) 1.13
Endostatin inhibits the growth of endometriotic lesions but does not affect fertility. Fertil Steril (2005) 1.08
Adipose tissue growth and regression are regulated by angiopoietin-1. Biochem Biophys Res Commun (2003) 1.05
Genome Wide Association Study to predict severe asthma exacerbations in children using random forests classifiers. BMC Med Genet (2011) 1.04
A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations. J Allergy Clin Immunol (2012) 1.01
PDE11A associations with asthma: results of a genome-wide association scan. J Allergy Clin Immunol (2010) 1.00
Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy. FASEB J (2008) 0.96
Association of variants in innate immune genes with asthma and eczema. Pediatr Allergy Immunol (2011) 0.93
Comprehensive genetic assessment of a functional TLR9 promoter polymorphism: no replicable association with asthma or asthma-related phenotypes. BMC Med Genet (2011) 0.89
Contrary effects of the receptor tyrosine kinase inhibitor vandetanib on constitutive and flow-stimulated nitric oxide elaboration in humans. Hypertension (2011) 0.89
Photocrosslinkable chitosan modified with angiopoietin-1 peptide, QHREDGS, promotes survival of neonatal rat heart cells. J Biomed Mater Res A (2010) 0.88
Regulatory haplotypes in ARG1 are associated with altered bronchodilator response. Am J Respir Crit Care Med (2010) 0.88
Nonsteroidal antiinflammatory drugs differentially suppress endometriosis in a murine model. Fertil Steril (2005) 0.87
The CD4+ T-cell transcriptome and serum IgE in asthma: IL17RB and the role of sex. BMC Pulm Med (2011) 0.86
Assessing the reproducibility of asthma genome-wide association studies in a general clinical population. J Allergy Clin Immunol (2011) 0.86
Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis. BMC Med Genomics (2014) 0.81
Predictive genomics of cardioembolic stroke. Stroke (2008) 0.80
QHREDGS enhances tube formation, metabolism and survival of endothelial cells in collagen-chitosan hydrogels. PLoS One (2013) 0.80
Polygenic heritability estimates in pharmacogenetics: focus on asthma and related phenotypes. Pharmacogenet Genomics (2013) 0.80
Development of a Pharmacogenetic Predictive Test in asthma: proof of concept. Pharmacogenet Genomics (2010) 0.79