Published in Mol Vis on January 25, 2005
Functions of the intermediate filament cytoskeleton in the eye lens. J Clin Invest (2009) 1.26
A novel mutation in the major intrinsic protein (MIP) associated with autosomal dominant congenital cataracts in a Chinese family. Mol Vis (2010) 1.13
Functional expression of aquaporins in embryonic, postnatal, and adult mouse lenses. Dev Dyn (2007) 1.11
Aquaporin 0 enhances gap junction coupling via its cell adhesion function and interaction with connexin 50. J Cell Sci (2010) 1.07
A proteome map of the zebrafish (Danio rerio) lens reveals similarities between zebrafish and mammalian crystallin expression. Mol Vis (2008) 0.98
Two distinct aquaporin 0s required for development and transparency of the zebrafish lens. Invest Ophthalmol Vis Sci (2010) 0.93
Expression profiling after retinal detachment and reattachment: a possible role for aquaporin-0. Invest Ophthalmol Vis Sci (2008) 0.92
Interaction of cytosolic glutamine synthetase of soybean root nodules with the C-terminal domain of the symbiosome membrane nodulin 26 aquaglyceroporin. J Biol Chem (2010) 0.92
PKC putative phosphorylation site Ser235 is required for MIP/AQP0 translocation to the plasma membrane. Mol Vis (2008) 0.85
Lengsin expression and function during zebrafish lens formation. Exp Eye Res (2008) 0.83
Major intrinsic protein (MIP) polymorphism is associated with age-related cataract in Chinese. Mol Vis (2011) 0.80
Endogenous retroviral insertion in Cryge in the mouse No3 cataract mutant. Genomics (2007) 0.77
A γA-Crystallin Mouse Mutant Secc with Small Eye, Cataract and Closed Eyelid. PLoS One (2016) 0.75
Connexin 50 Functions as an Adhesive Molecule and Promotes Lens Cell Differentiation. Sci Rep (2017) 0.75
Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat Genet (2006) 9.99
Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris. Nat Genet (2006) 4.55
Ageing and vision: structure, stability and function of lens crystallins. Prog Biophys Mol Biol (2004) 4.26
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming. Nat Genet (2009) 2.96
Glial fibrillary acidic protein mutations in infantile, juvenile, and adult forms of Alexander disease. Ann Neurol (2005) 2.16
Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity. Proc Natl Acad Sci U S A (2008) 2.07
High-resolution X-ray crystal structures of human gammaD crystallin (1.25 A) and the R58H mutant (1.15 A) associated with aculeiform cataract. J Mol Biol (2003) 2.02
Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect. J Invest Dermatol (2011) 1.97
Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants. Mol Vis (2002) 1.91
Filaggrin in atopic dermatitis. J Allergy Clin Immunol (2008) 1.89
Polydispersity of a mammalian chaperone: mass spectrometry reveals the population of oligomers in alphaB-crystallin. Proc Natl Acad Sci U S A (2003) 1.76
Age-related macular degeneration: genetics and biology coming together. Annu Rev Genomics Hum Genet (2014) 1.69
Microglia in the mouse retina alter the structure and function of retinal pigmented epithelial cells: a potential cellular interaction relevant to AMD. PLoS One (2009) 1.68
The persistence of atopic dermatitis and filaggrin (FLG) mutations in a US longitudinal cohort. J Allergy Clin Immunol (2012) 1.52
Crystal structure of truncated human betaB1-crystallin. Protein Sci (2003) 1.50
Age-related alterations in the dynamic behavior of microglia. Aging Cell (2010) 1.49
Microglial morphology and dynamic behavior is regulated by ionotropic glutamatergic and GABAergic neurotransmission. PLoS One (2011) 1.49
Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis. Invest Ophthalmol Vis Sci (2003) 1.48
Uptake of cholesterol by the retina occurs primarily via a low density lipoprotein receptor-mediated process. Mol Vis (2006) 1.47
Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis. J Allergy Clin Immunol (2007) 1.45
Wrapping the alpha-crystallin domain fold in a chaperone assembly. J Mol Biol (2005) 1.43
Ex vivo dynamic imaging of retinal microglia using time-lapse confocal microscopy. Invest Ophthalmol Vis Sci (2008) 1.42
Defining the human macula transcriptome and candidate retinal disease genes using EyeSAGE. Invest Ophthalmol Vis Sci (2006) 1.41
Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function. Am J Pathol (2011) 1.41
A retinal neuronal developmental wave of retinoschisin expression begins in ganglion cells during layer formation. Invest Ophthalmol Vis Sci (2004) 1.40
Regulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin. EMBO J (2006) 1.38
Urochordate betagamma-crystallin and the evolutionary origin of the vertebrate eye lens. Curr Biol (2005) 1.36
Regulation of dynamic behavior of retinal microglia by CX3CR1 signaling. Invest Ophthalmol Vis Sci (2009) 1.34
Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation. J Exp Med (2010) 1.33
Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects. J Allergy Clin Immunol (2013) 1.30
Pigment epithelium-derived factor in the monkey retinal pigment epithelium and interphotoreceptor matrix: apical secretion and distribution. Exp Eye Res (2004) 1.29
Waldenström's macroglobulinemia-associated retinopathy. Ophthalmology (2004) 1.26
Raman profiles of the stratum corneum define 3 filaggrin genotype-determined atopic dermatitis endophenotypes. J Allergy Clin Immunol (2010) 1.23
Filaggrin in atopic dermatitis. J Allergy Clin Immunol (2009) 1.22
Gene expression profile studies of human keratoconus cornea for NEIBank: a novel cornea-expressed gene and the absence of transcripts for aquaporin 5. Invest Ophthalmol Vis Sci (2005) 1.21
gammaN-crystallin and the evolution of the betagamma-crystallin superfamily in vertebrates. FEBS J (2005) 1.19
Immunological protein expression profile in Ccl2/Cx3cr1 deficient mice with lesions similar to age-related macular degeneration. Exp Eye Res (2008) 1.19
Mafs, Prox1, and Pax6 can regulate chicken betaB1-crystallin gene expression. J Biol Chem (2004) 1.18
betaA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during development. Mol Cell Neurosci (2007) 1.18
Retina-specific expression of 5A11/Basigin-2, a member of the immunoglobulin gene superfamily. Invest Ophthalmol Vis Sci (2003) 1.18
A novel imaging technique for experimental choroidal neovascularization. Invest Ophthalmol Vis Sci (2006) 1.17
Filaggrin null mutations and childhood atopic eczema: a population-based case-control study. J Allergy Clin Immunol (2008) 1.17
Clinical severity correlates with impaired barrier in filaggrin-related eczema. J Invest Dermatol (2008) 1.16
Deamidation in human gamma S-crystallin from cataractous lenses is influenced by surface exposure. Biochemistry (2002) 1.16
Haploinsufficiency is not the key mechanism of pathogenesis in a heterozygous Elovl4 knockout mouse model of STGD3 disease. Invest Ophthalmol Vis Sci (2006) 1.14
Increased solubility of lamins and redistribution of lamin C in X-linked Emery-Dreifuss muscular dystrophy fibroblasts. J Struct Biol (2002) 1.14
Adaptive Müller cell responses to microglial activation mediate neuroprotection and coordinate inflammation in the retina. J Neuroinflammation (2011) 1.11
Retinoschisin expression and localization in rodent and human pineal and consequences of mouse RS1 gene knockout. Mol Vis (2006) 1.11
Mutation of interfaces in domain-swapped human betaB2-crystallin. Protein Sci (2007) 1.10
Expressed sequence tag analysis of zebrafish eye tissues for NEIBank. Mol Vis (2005) 1.10
RPE cells internalize low-density lipoprotein (LDL) and oxidized LDL (oxLDL) in large quantities in vitro and in vivo. Invest Ophthalmol Vis Sci (2004) 1.09
PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets. Proc Natl Acad Sci U S A (2010) 1.08
Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema. J Invest Dermatol (2007) 1.08
A unique pattern of up- and down-regulation of chemokine receptor CXCR3 on inflammation-inducing Th1 cells. Eur J Immunol (2004) 1.08
Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma. Nat Genet (2012) 1.08
Pdlim2, a novel PDZ-LIM domain protein, interacts with alpha-actinins and filamin A. Invest Ophthalmol Vis Sci (2004) 1.08
Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency. J Allergy Clin Immunol (2012) 1.07
Transscleral-RPE permeability of PEDF and ovalbumin proteins: implications for subconjunctival protein delivery. Invest Ophthalmol Vis Sci (2005) 1.07
Macroglia-microglia interactions via TSPO signaling regulates microglial activation in the mouse retina. J Neurosci (2014) 1.06
Solution structure of (gamma)S-crystallin by molecular fragment replacement NMR. Protein Sci (2005) 1.06
Lens major intrinsic protein (MIP)/aquaporin 0 expression in rat lens epithelia explants requires fibroblast growth factor-induced ERK and JNK signaling. J Biol Chem (2004) 1.06
Specific filaggrin mutations cause ichthyosis vulgaris and are significantly associated with atopic dermatitis in Japan. J Invest Dermatol (2008) 1.06
The matricellular protein SPARC is expressed in human trabecular meshwork. Exp Eye Res (2003) 1.04
Mapping of the neonatal Fc receptor in the rodent eye. Invest Ophthalmol Vis Sci (2008) 1.04
Oligomers of mutant glial fibrillary acidic protein (GFAP) Inhibit the proteasome system in alexander disease astrocytes, and the small heat shock protein alphaB-crystallin reverses the inhibition. J Biol Chem (2010) 1.03
A2E accumulation influences retinal microglial activation and complement regulation. Neurobiol Aging (2012) 1.01
Regulation of ocular angiogenesis by Notch signaling: implications in neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci (2011) 1.00
Preservation of cone photoreceptors after a rapid yet transient degeneration and remodeling in cone-only Nrl-/- mouse retina. J Neurosci (2012) 1.00
Photopic ERG negative response from amacrine cell signaling in RCS rat retinal degeneration. Invest Ophthalmol Vis Sci (2008) 0.99
The X-ray crystal structure of human gamma S-crystallin C-terminal domain. J Biol Chem (2001) 0.98
Mutated mouse and human myocilins have similar properties and do not block general secretory pathway. Invest Ophthalmol Vis Sci (2006) 0.98
Biophysical properties of gammaC-crystallin in human and mouse eye lens: the role of molecular dipoles. J Mol Biol (2007) 0.98
An intramembrane glutamic acid governs peripherin/rds function for photoreceptor disk morphogenesis. Invest Ophthalmol Vis Sci (2007) 0.97
Unfolding crystallins: the destabilizing role of a beta-hairpin cysteine in betaB2-crystallin by simulation and experiment. Protein Sci (2005) 0.96
A specific interaction between muskelin and the cyclin-dependent kinase 5 activator p39 promotes peripheral localization of muskelin. J Biol Chem (2005) 0.96
Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk. J Allergy Clin Immunol (2008) 0.96
A role for lengsin, a recruited enzyme, in terminal differentiation in the vertebrate lens. J Biol Chem (2008) 0.96
sHSP in the eye lens: crystallin mutations, cataract and proteostasis. Int J Biochem Cell Biol (2012) 0.95
A single destabilizing mutation (F9S) promotes concerted unfolding of an entire globular domain in gammaS-crystallin. J Mol Biol (2010) 0.95
Doxycycline-mediated inhibition of choroidal neovascularization. Invest Ophthalmol Vis Sci (2009) 0.95
Silencing of the CHM gene alters phagocytic and secretory pathways in the retinal pigment epithelium. Invest Ophthalmol Vis Sci (2009) 0.94
Explosive expansion of betagamma-crystallin genes in the ancestral vertebrate. J Mol Evol (2010) 0.94
Morphological characterization of the retinal degeneration in three strains of mice carrying the rd-3 mutation. Vis Neurosci (2006) 0.93
Central immunotolerance in transgenic mice expressing a foreign antigen under control of the rhodopsin promoter. Invest Ophthalmol Vis Sci (2004) 0.93
In vivo heteromer formation. Expression of soluble betaA4-crystallin requires coexpression of a heteromeric partner. FEBS J (2006) 0.93
Development of a microarray chip for gene expression in rabbit ocular research. Mol Vis (2007) 0.92
EyeSite: a semi-automated database of protein families in the eye. Nucleic Acids Res (2004) 0.92
Minocycline attenuates photoreceptor degeneration in a mouse model of subretinal hemorrhage microglial: inhibition as a potential therapeutic strategy. Am J Pathol (2011) 0.91
Unique and recurrent mutations in the filaggrin gene in Singaporean Chinese patients with ichthyosis vulgaris. J Invest Dermatol (2008) 0.90
Activation of STAT signaling pathways and induction of suppressors of cytokine signaling (SOCS) proteins in mammalian lens by growth factors. Invest Ophthalmol Vis Sci (2004) 0.89
A survey of molecular expression by photoreceptors after experimental retinal detachment. Invest Ophthalmol Vis Sci (2002) 0.89
gammaE-crystallin recruitment to the plasma membrane by specific interaction between lens MIP/aquaporin-0 and gammaE-crystallin. Invest Ophthalmol Vis Sci (2004) 0.89
Differentiation of human retinal pigment epithelial cells into neuronal phenotype by N-(4-hydroxyphenyl)retinamide. J Neurochem (2003) 0.89
De novo occurrence of the filaggrin mutation p.R501X with prevalent mutation c.3321delA in a Japanese family with ichthyosis vulgaris complicated by atopic dermatitis. J Invest Dermatol (2007) 0.89
Expression of GITR ligand abrogates immunosuppressive function of ocular tissue and differentially modulates inflammatory cytokines and chemokines. Eur J Immunol (2006) 0.89