Bernhard Schermer

Author PubWeight™ 101.02‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 2007 34.03
2 Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nat Genet 2005 6.67
3 Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination. Nat Genet 2003 5.24
4 Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis. Nat Genet 2003 4.14
5 Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia. Am J Hum Genet 2008 2.74
6 Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling. Mol Cell Biol 2003 2.69
7 Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. J Am Soc Nephrol 2008 2.69
8 Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. Cell 2012 2.54
9 Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels. Proc Natl Acad Sci U S A 2006 2.16
10 Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation. EMBO J 2005 2.12
11 PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome. J Clin Invest 2010 1.85
12 Nephrocystin specifically localizes to the transition zone of renal and respiratory cilia and photoreceptor connecting cilia. J Am Soc Nephrol 2006 1.79
13 Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics. J Clin Invest 2011 1.60
14 Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol 2011 1.49
15 Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem 2008 1.43
16 The carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1. J Biol Chem 2003 1.42
17 KIBRA modulates directional migration of podocytes. J Am Soc Nephrol 2008 1.36
18 NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway. J Cell Biol 2011 1.34
19 Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags. Nat Med 2013 1.22
20 Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1. Genome Med 2009 1.15
21 p35, the non-cyclin activator of Cdk5, protects podocytes against apoptosis in vitro and in vivo. Kidney Int 2010 1.12
22 Podocin organizes ion channel-lipid supercomplexes: implications for mechanosensation at the slit diaphragm. Nephron Exp Nephrol 2007 1.03
23 Light microscopic visualization of podocyte ultrastructure demonstrates oscillating glomerular contractions. Am J Pathol 2012 1.03
24 AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis. EMBO J 2012 1.02
25 Intrinsic proinflammatory signaling in podocytes contributes to podocyte damage and prolonged proteinuria. Am J Physiol Renal Physiol 2012 1.00
26 The von Hippel Lindau tumor suppressor limits longevity. J Am Soc Nephrol 2009 1.00
27 Interaction of 14-3-3 protein with regulator of G protein signaling 7 is dynamically regulated by tumor necrosis factor-alpha. J Biol Chem 2002 0.98
28 Listeria monocytogenes infection in macrophages induces vacuolar-dependent host miRNA response. PLoS One 2011 0.97
29 Mutations in NEK8 link multiple organ dysplasia with altered Hippo signalling and increased c-MYC expression. Hum Mol Genet 2013 0.96
30 Clinical spectrum and pathogenesis of nephronophthisis. Curr Opin Nephrol Hypertens 2012 0.94
31 Comparative analysis of Neph gene expression in mouse and chicken development. Histochem Cell Biol 2011 0.91
32 Extracellular phosphorylation of collagen XVII by ecto-casein kinase 2 inhibits ectodomain shedding. J Biol Chem 2007 0.91
33 Dysregulated autophagy contributes to podocyte damage in Fabry's disease. PLoS One 2013 0.91
34 Conditional loss of kidney microRNAs results in congenital anomalies of the kidney and urinary tract (CAKUT). J Mol Med (Berl) 2013 0.90
35 The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ. Hum Mol Genet 2012 0.90
36 Label-free quantitative proteomic analysis of the YAP/TAZ interactome. Am J Physiol Cell Physiol 2014 0.90
37 The ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate β-catenin signaling. J Biol Chem 2012 0.89
38 Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia. J Biol Chem 2011 0.87
39 Breaking the chain at the membrane: paraoxonase 2 counteracts lipid peroxidation at the plasma membrane. FASEB J 2014 0.87
40 The centrosomal kinase Plk1 localizes to the transition zone of primary cilia and induces phosphorylation of nephrocystin-1. PLoS One 2012 0.86
41 Loss of the Birt-Hogg-Dubé gene product folliculin induces longevity in a hypoxia-inducible factor-dependent manner. Aging Cell 2013 0.81
42 Putting the brakes on p53-driven apoptosis. Cell Cycle 2012 0.81
43 A disease-causing mutation illuminates the protein membrane topology of the kidney-expressed prohibitin homology (PHB) domain protein podocin. J Biol Chem 2014 0.79
44 Transition zone proteins and cilia dynamics. Nat Genet 2011 0.78
45 Comparative phosphoproteomic analysis of mammalian glomeruli reveals conserved podocin C-terminal phosphorylation as a determinant of slit diaphragm complex architecture. Proteomics 2015 0.78
46 Characterization of a short isoform of the kidney protein podocin in human kidney. BMC Nephrol 2013 0.77
47 The BAR domain protein PICK1 regulates cell recognition and morphogenesis by interacting with Neph proteins. Mol Cell Biol 2011 0.75