PubRank

Seth A Darst

Author PubWeight™ 100.81‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex. Science 2002 6.17
2 Structural basis of transcription initiation: RNA polymerase holoenzyme at 4 A resolution. Science 2002 5.18
3 Structure of the bacterial RNA polymerase promoter specificity sigma subunit. Mol Cell 2002 4.22
4 Bacterial RNA polymerases: the wholo story. Curr Opin Struct Biol 2003 4.12
5 Structure and function of the transcription elongation factor GreB bound to bacterial RNA polymerase. Cell 2003 3.14
6 Catabolite activator protein: DNA binding and transcription activation. Curr Opin Struct Biol 2004 2.91
7 Structural basis for promoter-10 element recognition by the bacterial RNA polymerase σ subunit. Cell 2011 2.82
8 Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA. Mol Cell 2003 2.50
9 Insights into antiparallel microtubule crosslinking by PRC1, a conserved nonmotor microtubule binding protein. Cell 2010 2.50
10 The structural basis for promoter -35 element recognition by the group IV sigma factors. PLoS Biol 2006 2.18
11 Structural basis for bacterial transcription-coupled DNA repair. Cell 2006 2.16
12 Marking and measuring single microtubules by PRC1 and kinesin-4. Cell 2013 1.86
13 A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria. Mol Cell 2007 1.76
14 Sigma and RNA polymerase: an on-again, off-again relationship? Mol Cell 2005 1.74
15 Structural basis of transcriptional pausing in bacteria. Cell 2013 1.71
16 Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase. EMBO J 2005 1.71
17 Complete structural model of Escherichia coli RNA polymerase from a hybrid approach. PLoS Biol 2010 1.69
18 Structure of a ternary transcription activation complex. Mol Cell 2004 1.68
19 Molecular evolution of multisubunit RNA polymerases: sequence analysis. J Mol Biol 2009 1.67
20 Crystal structure of the flagellar sigma/anti-sigma complex sigma(28)/FlgM reveals an intact sigma factor in an inactive conformation. Mol Cell 2004 1.61
21 Structure of microcin J25, a peptide inhibitor of bacterial RNA polymerase, is a lassoed tail. J Am Chem Soc 2003 1.56
22 Regulation of bacterial RNA polymerase sigma factor activity: a structural perspective. Curr Opin Microbiol 2008 1.52
23 Region 4 of sigma as a target for transcription regulation. Mol Microbiol 2003 1.50
24 Bacterial sigma factors: a historical, structural, and genomic perspective. Annu Rev Microbiol 2014 1.49
25 Utilization of variably spaced promoter-like elements by the bacterial RNA polymerase holoenzyme during early elongation. Mol Microbiol 2010 1.48
26 Molecular evolution of multisubunit RNA polymerases: structural analysis. J Mol Biol 2009 1.45
27 Protein-protein and protein-DNA interactions of sigma70 region 4 involved in transcription activation by lambdacI. J Mol Biol 2002 1.42
28 Structure and function of lineage-specific sequence insertions in the bacterial RNA polymerase beta' subunit. J Mol Biol 2005 1.41
29 Autoregulation of a bacterial sigma factor explored by using segmental isotopic labeling and NMR. Proc Natl Acad Sci U S A 2002 1.36
30 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of σ70 domain 1.1. Proc Natl Acad Sci U S A 2013 1.35
31 Structure of the filamentous phage pIV multimer by cryo-electron microscopy. J Mol Biol 2003 1.34
32 How to switch off a histidine kinase: crystal structure of Geobacillus stearothermophilus KinB with the inhibitor Sda. J Mol Biol 2008 1.33
33 Crystal structure of the Bacillus stearothermophilus anti-sigma factor SpoIIAB with the sporulation sigma factor sigmaF. Cell 2002 1.32
34 Structural basis for the bacterial transcription-repair coupling factor/RNA polymerase interaction. Nucleic Acids Res 2010 1.30
35 Structure and function of CarD, an essential mycobacterial transcription factor. Proc Natl Acad Sci U S A 2013 1.25
36 Rifamycins do not function by allosteric modulation of binding of Mg2+ to the RNA polymerase active center. Proc Natl Acad Sci U S A 2008 1.16
37 Crystal structure of Thermus aquaticus Gfh1, a Gre-factor paralog that inhibits rather than stimulates transcript cleavage. J Mol Biol 2005 1.11
38 Initiation of transcription-coupled repair characterized at single-molecule resolution. Nature 2012 1.10
39 Crystal structure of the Escherichia coli regulator of sigma70, Rsd, in complex with sigma70 domain 4. J Mol Biol 2007 1.10
40 Interaction of CarD with RNA polymerase mediates Mycobacterium tuberculosis viability, rifampin resistance, and pathogenesis. J Bacteriol 2012 1.10
41 The bacterial transcription repair coupling factor. Curr Opin Struct Biol 2007 1.06
42 Crystal structures of the ADP and ATP bound forms of the Bacillus anti-sigma factor SpoIIAB in complex with the anti-anti-sigma SpoIIAA. J Mol Biol 2004 1.05
43 Crystal structure of bacteriophage lambda cII and its DNA complex. Mol Cell 2005 1.04
44 Recombinant Thermus aquaticus RNA polymerase for structural studies. J Mol Biol 2006 1.01
45 Crystal structure of Escherichia coli Rnk, a new RNA polymerase-interacting protein. J Mol Biol 2008 0.99
46 Rapid isolation and identification of bacteriophage T4-encoded modifications of Escherichia coli RNA polymerase: a generic method to study bacteriophage/host interactions. J Proteome Res 2008 0.98
47 Promoter melting triggered by bacterial RNA polymerase occurs in three steps. Proc Natl Acad Sci U S A 2010 0.97
48 An altered-specificity DNA-binding mutant of Escherichia coli sigma70 facilitates the analysis of sigma70 function in vivo. Mol Microbiol 2005 0.95
49 Disulfide cross-linking indicates that FlgM-bound and free sigma28 adopt similar conformations. Proc Natl Acad Sci U S A 2006 0.94
50 Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein. Cell 2012 0.92
51 Derepression of bacterial transcription-repair coupling factor is associated with a profound conformational change. J Mol Biol 2010 0.91
52 Identification of the gate regions in the primary structure of the secretin pIV. Mol Microbiol 2010 0.91
53 A novel method for the production of in vivo-assembled, recombinant Escherichia coli RNA polymerase lacking the α C-terminal domain. Protein Sci 2011 0.89
54 Crystallization and preliminary structure determination of Escherichia coli Mfd, the transcription-repair coupling factor. Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 0.89
55 Temporal regulation of gene expression of the Thermus thermophilus bacteriophage P23-45. J Mol Biol 2010 0.88
56 Crystal structure of the in vivo-assembled Bacillus subtilis Spx/RNA polymerase alpha subunit C-terminal domain complex. J Struct Biol 2009 0.87
57 Crystal structures of the glycopeptide sulfotransferase Teg12 in a complex with the teicoplanin aglycone. Biochemistry 2010 0.86
58 Crystallographic analysis of Thermus aquaticus RNA polymerase holoenzyme and a holoenzyme/promoter DNA complex. Methods Enzymol 2003 0.84
59 Crystal structure of the bacteriophage T4 late-transcription coactivator gp33 with the β-subunit flap domain of Escherichia coli RNA polymerase. Proc Natl Acad Sci U S A 2011 0.83
60 Phage-encoded inhibitor of Staphylococcus aureus transcription exerts context-dependent effects on promoter function in a modified Escherichia coli-based transcription system. J Bacteriol 2013 0.82
61 Promoter recognition by bacterial alternative sigma factors: the price of high selectivity? Genes Dev 2009 0.81
62 RNA-Seq reveals differential gene expression in Staphylococcus aureus with single-nucleotide resolution. PLoS One 2013 0.80
63 The 2.7 Å resolution structure of the glycopeptide sulfotransferase Teg14. Acta Crystallogr D Biol Crystallogr 2010 0.79
64 Crystallographic analysis of an RNA polymerase σ-subunit fragment complexed with -10 promoter element ssDNA: quadruplex formation as a possible tool for engineering crystal contacts in protein-ssDNA complexes. Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 0.77
65 Biochemical insights into the function of phage G1 gp67 in Staphylococcus aureus. Bacteriophage 2013 0.76
66 [11] Two-dimensional protein crystals in aid of three-dimensional protein crystal growth. Methods Enzymol 1997 0.75