Brian Tomlinson

Author PubWeight™ 113.79‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Impact of TNF inhibition on insulin resistance and lipids levels in patients with rheumatoid arthritis. Clin Rheumatol 2007 2.18
2 Ganoderma lucidum ("Lingzhi"), a Chinese medicinal mushroom: biomarker responses in a controlled human supplementation study. Br J Nutr 2004 1.58
3 Patients with systemic lupus erythematosus show increased platelet activation and endothelial dysfunction induced by acute hyperhomocysteinemia. J Rheumatol 2003 1.58
4 OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine. Pharmacogenet Genomics 2008 1.50
5 The beneficial effects of Tai Chi Chuan on blood pressure and lipid profile and anxiety status in a randomized controlled trial. J Altern Complement Med 2003 1.43
6 Association of the D8S282 marker near the lipoprotein lipase gene locus with systolic blood pressure in healthy Chinese subjects. J Hypertens 2002 1.38
7 Total antioxidant and ascorbic acid content of fresh fruits and vegetables: implications for dietary planning and food preservation. Br J Nutr 2002 1.19
8 The effects of nasal continuous positive airway pressure on platelet activation in obstructive sleep apnea syndrome. Chest 2004 1.17
9 100 or 30 years after Janeway or Bartter, Healthwatch helps avoid 'flying blind'. Biomed Pharmacother 2004 1.15
10 Prevalence and clinicopathological characteristics of islet amyloid in chinese patients with type 2 diabetes. Diabetes 2003 1.13
11 Protective effects of trilinolein extracted from panax notoginseng against cardiovascular disease. Acta Pharmacol Sin 2002 1.13
12 Association between adherence to statin therapy and lipid control in Hong Kong Chinese patients at high risk of coronary heart disease. Br J Clin Pharmacol 2004 1.10
13 Subclinical carotid atherosclerosis in patients with psoriatic arthritis. Arthritis Rheum 2008 1.09
14 Innate and adaptive cellular immunity in flavivirus-naïve human recipients of a live-attenuated dengue serotype 3 vaccine produced in Vero cells (VDV3). Vaccine 2006 1.08
15 Lessons from the severe acute respiratory syndrome outbreak in Hong Kong. Emerg Infect Dis 2003 1.06
16 Ezetimibe treatment should be considered for patients with sitosterolemia. Pediatr Nephrol 2014 1.06
17 Identification of IGF1, SLC4A4, WWOX, and SFMBT1 as hypertension susceptibility genes in Han Chinese with a genome-wide gene-based association study. PLoS One 2012 1.03
18 Pharmacogenetics and herb-drug interactions: experience with Ginkgo biloba and omeprazole. Pharmacogenetics 2004 1.02
19 Effects of polymorphisms in ABCG2, SLCO1B1, SLC10A1 and CYP2C9/19 on plasma concentrations of rosuvastatin and lipid response in Chinese patients. Pharmacogenomics 2013 0.99
20 Effects of Tai Chi and resistance training on cardiovascular risk factors in elderly Chinese subjects: a 12-month longitudinal, randomized, controlled intervention study. Clin Endocrinol (Oxf) 2005 0.98
21 An affected pedigree member analysis of linkage between the dopamine D2 receptor gene TaqI polymorphism and obesity and hypertension. Int J Cardiol 2005 0.97
22 Cholesterol goal attainment in patients with coronary heart disease and elevated coronary risk: results of the Hong Kong hospital audit study. Value Health 2008 0.96
23 A randomised study comparing the efficacy and safety of rosuvastatin with atorvastatin for achieving lipid goals in clinical practice in Asian patients at high risk of cardiovascular disease (DISCOVERY-Asia study). Curr Med Res Opin 2007 0.95
24 Measuring job stress and family stress in Chinese working women: a validation study focusing on blood pressure and psychosomatic symptoms. Women Health 2004 0.95
25 Telmisartan inhibits vasoconstriction via PPARγ-dependent expression and activation of endothelial nitric oxide synthase. Cardiovasc Res 2010 0.94
26 A genome-wide linkage and association scan reveals novel loci for hypertension and blood pressure traits. PLoS One 2012 0.94
27 Correlation of large artery intracranial occlusive disease with carotid intima-media thickness and presence of carotid plaque. Stroke 2012 0.94
28 Associations of polymorphisms in the apolipoprotein A1/C3/A4/A5 gene cluster with familial combined hyperlipidaemia in Hong Kong Chinese. Atherosclerosis 2009 0.93
29 CYP2C9, but not CYP2C19, polymorphisms affect the pharmacokinetics and pharmacodynamics of glyburide in Chinese subjects. Clin Pharmacol Ther 2005 0.92
30 Linkage of angiotensinogen gene polymorphisms with hypertension in a sibling study of Hong Kong Chinese. J Hypertens 2010 0.91
31 Study of the effects of total flavonoids of Astragalus on atherosclerosis formation and potential mechanisms. Oxid Med Cell Longev 2012 0.91
32 Rimonabant for the treatment of obesity. Recent Pat Cardiovasc Drug Discov 2008 0.91
33 Do the lipid responses to rosuvastatin and atorvastatin differ between Chinese and Caucasians? Comparison of the DISCOVERY-Hong Kong study with other DISCOVERY studies. Int J Cardiol 2013 0.91
34 Antihypertensive effects of tannins isolated from traditional Chinese herbs as non-specific inhibitors of angiontensin converting enzyme. Life Sci 2003 0.90
35 Associations of apolipoprotein E exon 4 and lipoprotein lipase S447X polymorphisms with acute ischemic stroke and myocardial infarction. Clin Chem Lab Med 2006 0.90
36 Variability in renal clearance of substrates for renal transporters in chinese subjects. J Clin Pharmacol 2006 0.90
37 Paraoxonase 1 gene Q192R polymorphism affects stroke and myocardial infarction risk. Clin Biochem 2006 0.90
38 Bernard Lerer: recipient of the 2014 inaugural Werner Kalow Responsible Innovation Prize in Global Omics and Personalized Medicine (Pacific Rim Association for Clinical Pharmacogenetics). OMICS 2014 0.89
39 Leflunomide in the treatment of rheumatoid arthritis. Clin Ther 2004 0.89
40 Clinical and economic impact of clinical pharmacy service on hyperlipidemic management in Hong Kong. J Cardiovasc Pharmacol Ther 2010 0.88
41 Effects of vitamins C and E on oxidative stress markers and endothelial function in patients with systemic lupus erythematosus: a double blind, placebo controlled pilot study. J Rheumatol 2005 0.87
42 Weight management and current options in pharmacotherapy: orlistat and sibutramine. Clin Ther 2003 0.87
43 Middle cerebral artery stenosis in type II diabetic Chinese patients is associated with conventional risk factors but not with polymorphisms of the renin-angiotensin system genes. Cerebrovasc Dis 2003 0.87
44 Febuxostat in the management of hyperuricemia and chronic gout: a review. Ther Clin Risk Manag 2008 0.87
45 Middle cerebral artery stenosis increased the risk of vascular disease mortality among type 2 diabetic patients. Cerebrovasc Dis 2008 0.87
46 Human metapneumovirus-associated atypical pneumonia and SARS. Emerg Infect Dis 2004 0.86
47 Assessing adherence to statin therapy using patient report, pill count, and an electronic monitoring device. Am J Health Syst Pharm 2005 0.86
48 Association of a genetic variant in the apolipoprotein A5 gene with the metabolic syndrome in Chinese. Clin Endocrinol (Oxf) 2011 0.86
49 The role of angiotensin II type 1 receptor antagonists in elderly patients with hypertension. Drugs Aging 2006 0.85
50 The ABCG2 transporter and its relations with the pharmacokinetics, drug interaction and lipid-lowering effects of statins. Expert Opin Drug Metab Toxicol 2010 0.85
51 A systematic review of lifestyle modification and glucose intolerance in the prevention of type 2 diabetes. Curr Diabetes Rev 2010 0.85
52 Pathogenic mutations of the lipoprotein lipase gene in Chinese patients with hypertriglyceridemic type 2 diabetes. Hum Mutat 2003 0.85
53 Increasing severity of cardiovascular risk factors with increasing middle cerebral artery stenotic involvement in type 2 diabetic Chinese patients with asymptomatic cerebrovascular disease. Diabetes Care 2004 0.85
54 Niacin for reduction of cardiovascular risk. N Engl J Med 2014 0.85
55 A polymorphism in transforming growth factor-β1 is associated with carotid plaques and increased carotid intima-media thickness in older Chinese men: the Guangzhou Biobank Cohort Study-Cardiovascular Disease Subcohort. Atherosclerosis 2010 0.85
56 A modified two-portion absorption model to describe double-peak absorption profiles of ranitidine. Clin Pharmacokinet 2003 0.84
57 Liver fat reduction with niacin is influenced by DGAT-2 polymorphisms in hypertriglyceridemic patients. J Lipid Res 2012 0.84
58 A case-control study of apoA5 -1131T-->C polymorphism that examines the role of triglyceride levels in diabetic nephropathy. J Diabetes Complications 2007 0.84
59 Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003 0.84
60 Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br J Nutr 2011 0.84
61 Omeprazole as a CYP2C19 marker in Chinese subjects: assessment of its gene-dose effect and intrasubject variability. J Clin Pharmacol 2004 0.84
62 Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy. Hum Genet 2013 0.84
63 Association of two apolipoprotein A-I gene MspI polymorphisms with lipid and blood pressure levels. Int J Cardiol 2005 0.84
64 The lipoprotein lipase gene HindIII polymorphism is associated with lipid levels in early-onset type 2 diabetic patients. Metabolism 2003 0.84
65 Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients. Pharmacogenet Genomics 2010 0.83
66 A study of the effect of oral glucose loading on plasma oxidant:antioxidant balance in normal subjects. Eur J Nutr 2004 0.83
67 Heterozygous familial hypercholesterolemia in Hong Kong Chinese. Study of 252 cases. Int J Cardiol 2012 0.82
68 Tumour necrosis factor alpha blockade is associated with sustained regression of carotid intima-media thickness for patients with active psoriatic arthritis: a 2-year pilot study. Ann Rheum Dis 2010 0.82
69 Effects of some common food constituents on cardiovascular disease. ISRN Cardiol 2011 0.82
70 A single nucleotide polymorphism in APOA5 determines triglyceride levels in Hong Kong and Guangzhou Chinese. Eur J Hum Genet 2010 0.81
71 Ganoderma lucidum ('Lingzhi'); acute and short-term biomarker response to supplementation. Int J Food Sci Nutr 2004 0.81
72 Health promotion in older Chinese: a 12-month cluster randomized controlled trial of pedometry and "peer support". Med Sci Sports Exerc 2012 0.81
73 CYP2C19 genotype has a major influence on labetalol pharmacokinetics in healthy male Chinese subjects. Eur J Clin Pharmacol 2012 0.81
74 The pharmacogenetics of β-adrenergic receptor antagonists in the treatment of hypertension and heart failure. Expert Opin Drug Metab Toxicol 2012 0.81
75 Prevention of coronary artery disease: the south Asian paradox. Lancet 2003 0.81
76 Safety and efficacy of Ganoderma lucidum (lingzhi) and San Miao San supplementation in patients with rheumatoid arthritis: a double-blind, randomized, placebo-controlled pilot trial. Arthritis Rheum 2007 0.81
77 Validation of A&D TM-2430 upper-arm blood pressure monitor for ambulatory blood pressure monitoring in children and adolescents, according to the British Hypertension Society protocol. Blood Press Monit 2012 0.81
78 Targeting the ABCG2-overexpressing multidrug resistant (MDR) cancer cells by PPARγ agonists. Br J Pharmacol 2013 0.81
79 Effect of hepatic lipase -514C->T polymorphism and its interactions with apolipoprotein C3 -482C->T and apolipoprotein E exon 4 polymorphisms on the risk of nephropathy in chinese type 2 diabetic patients. Diabetes Care 2005 0.80
80 Attainment of normal lipid levels among patients on lipid-modifying therapy in Hong Kong. Adv Ther 2012 0.80
81 Association of glomerulopathy with the 5'-end polymorphism of the aldose reductase gene and renal insufficiency in type 2 diabetic patients. Diabetes 2004 0.80
82 Effects of statin treatments and polymorphisms in UGT1A1 and SLCO1B1 on serum bilirubin levels in Chinese patients with hypercholesterolaemia. Atherosclerosis 2012 0.80
83 Methylenetetrahydrofolate reductase gene A222V polymorphism and risk of ischemic stroke. Clin Chem Lab Med 2004 0.80
84 Association of two apolipoprotein A-I gene MspI polymorphisms with high density lipoprotein (HDL)-cholesterol levels and indices of obesity in selected healthy Chinese subjects and in patients with early-onset type 2 diabetes. Clin Endocrinol (Oxf) 2003 0.79
85 Interindividual and intraindividual variability of the urinary 6beta-Hydroxycortisol/Cortisol ratio in Chinese subjects: implications of its use for evaluating CYP3A activity. J Clin Pharmacol 2004 0.79
86 Pharmacogenomics of lipid-lowering therapies. Pharmacogenomics 2013 0.79
87 Management of nephropathy in patients with type 2 diabetes. Chin Med J (Engl) 2002 0.79
88 Effect of central obesity, low high-density lipoprotein cholesterol and C-reactive protein polymorphisms on C-reactive protein levels during treatment with Rosuvastatin (10 mg Daily). Am J Cardiol 2010 0.79
89 Whole soy, but not purified daidzein, had a favorable effect on improvement of cardiovascular risks: a 6-month randomized, double-blind, and placebo-controlled trial in equol-producing postmenopausal women. Mol Nutr Food Res 2013 0.79
90 The effects of candesartan and ramipril on adrenal catecholamine release in anaesthetized dogs. Eur J Pharmacol 2004 0.79
91 Tesamorelin, a human growth hormone releasing factor analogue. Expert Opin Investig Drugs 2009 0.79
92 Beneficial effects on blood pressure and lipid profile of programmed exercise training in subjects with white coat hypertension. Am J Hypertens 2002 0.78
93 Increasing insulin resistance contributes to worsening glycaemic and lipid profiles in older Chinese subjects. Diabetes Res Clin Pract 2004 0.78
94 Improving sublingual delivery of weak base compounds using pH(max) concept: application to propranolol. Eur J Pharm Sci 2010 0.78
95 Clinicopathologic characteristics of nodular glomerulosclerosis in Chinese patients with type 2 diabetes. Am J Kidney Dis 2004 0.78
96 Early investigational drugs targeting PPAR-α for the treatment of metabolic disease. Expert Opin Investig Drugs 2015 0.78
97 Current Perspectives on rosuvastatin. Integr Blood Press Control 2013 0.78
98 Hyperglycaemia and vitamin D: a systematic overview. Curr Diabetes Rev 2012 0.78
99 Translational Research for Improving the Care of Familial Hypercholesterolemia: The "Ten Countries Study" and Beyond. J Atheroscler Thromb 2016 0.78
100 Effects of phenotypic and genotypic factors on the lipid responses to niacin in Chinese patients with dyslipidemia. Medicine (Baltimore) 2015 0.77
101 Theranostics meets traditional Chinese medicine: rational prediction of drug-herb interactions. Expert Rev Mol Diagn 2012 0.77
102 Antioxidant effect of lercanidipine. Hypertension 2003 0.77
103 A three-stage genome-wide association study combining multilocus test and gene expression analysis for young-onset hypertension in Taiwan Han Chinese. Am J Hypertens 2014 0.77
104 Effects of the angiotensin II type 1 receptor antagonist valsartan on the expression of superoxide dismutase in hypertensive patients. J Clin Pharmacol 2007 0.77
105 Intronic variants in SLCO1B1 related to statin-induced myopathy are associated with the low-density lipoprotein cholesterol response to statins in Chinese patients with hyperlipidaemia. Pharmacogenet Genomics 2012 0.77
106 Association between metabolic syndrome and carotid atherosclerosis: a community-based study in Hong Kong. Metab Syndr Relat Disord 2013 0.77
107 Evaluation of the pharmacokinetics and drug interactions of the two recently developed statins, rosuvastatin and pitavastatin. Expert Opin Drug Metab Toxicol 2013 0.77
108 An update on the management of nephropathy in type 2 diabetes. J Chin Med Assoc 2003 0.77
109 Overview of dietary influences on atherosclerotic vascular disease: epidemiology and prevention. Cardiovasc Hematol Disord Drug Targets 2007 0.77
110 Association of erectile dysfunction with cardiovascular risk factors and increasing existing vascular disease in male chinese type 2 diabetic patients. Diabetes Care 2005 0.77
111 Impact of CYP2D6 polymorphisms on the pharmacokinetics of lovastatin in Chinese subjects. Eur J Clin Pharmacol 2012 0.77
112 Effects of grapefruit juice and SLCO1B1 388A>G polymorphism on the pharmacokinetics of pitavastatin. Drug Metab Pharmacokinet 2012 0.77
113 Combination therapy in hypertension: an Asia-Pacific consensus viewpoint. Curr Med Res Opin 2015 0.77
114 Clinical pharmacokinetics of buffered propranolol sublingual tablet (Promptol™)-application of a new "physiologically based" model to assess absorption and disposition. AAPS J 2013 0.77
115 Renin-angiotensin system gene polymorphisms and retinopathy in chinese patients with type 2 diabetes. Diabetes Care 2003 0.77
116 Effect of multidrug resistance gene-1 (ABCB1) polymorphisms on the single-dose pharmacokinetics of cloxacillin in healthy adult Chinese men. Clin Ther 2009 0.76
117 Higher islet amyloid load in men than in women with type 2 diabetes mellitus. Pancreas 2008 0.76
118 Expression and activity of ABCG2, but not ABCB1 or OATP1B1, are associated with cholesterol levels: evidence from in vitro and in vivo experiments. Pharmacogenomics 2014 0.76
119 Stereoselective interaction of manidipine and grapefruit juice: a new twist on an old tale. Br J Clin Pharmacol 2006 0.76
120 Polymorphisms in apolipoprotein E and apolipoprotein A-V do not influence the lipid response to rosuvastatin but are associated with baseline lipid levels in Chinese patients with hyperlipidemia. J Clin Lipidol 2012 0.76
121 Managlinat dialanetil, a fructose-1,6-bisphosphatase inhibitor for the treatment of type 2 diabetes. Curr Opin Investig Drugs 2007 0.76
122 Prevention of macrovascular disease in type 2 diabetic patients: blockade of the renin-angiotensin-aldosterone system. Curr Diabetes Rev 2008 0.76
123 Integrated guidance on the care of familial hypercholesterolaemia from the International FH Foundation: executive summary. J Atheroscler Thromb 2014 0.76
124 The farnesoid X receptor -1G>T polymorphism influences the lipid response to rosuvastatin. J Lipid Res 2012 0.76
125 Associations between the genotypes and phenotype of CYP3A and the lipid response to simvastatin in Chinese patients with hypercholesterolemia. Pharmacogenomics 2013 0.76
126 Genotype-phenotype studies of six novel LPL mutations in Chinese patients with hypertriglyceridemia. Hum Mutat 2002 0.76
127 Potential effects of NPC1L1 polymorphisms in protecting against clinical disease in a chinese family with sitosterolaemia. J Atheroscler Thromb 2014 0.76
128 Comments on "CYP3AP1*3 allele is associated with lipid-lowering efficacy of simvastatin and atorvastatin in Chinese women". J Clin Pharmacol 2012 0.75
129 Raising high-density lipoprotein: for better or worse? Heart 2010 0.75
130 Clinical Predictors and Long-term Impact of Acute Kidney Injury on Progression of Diabetic Kidney Disease in Chinese Patients With Type 2 Diabetes. Diabetes 2022 0.75
131 Clinical efficacy of rosuvastatin in lipid management in Chinese patients in Hong Kong. Chin Med J (Engl) 2009 0.75
132 Lipid-lowing pharmacogenomics in Chinese patients. Expert Rev Cardiovasc Ther 2013 0.75
133 The use of medications in the secondary prevention of coronary artery disease in the Asian region. Curr Med Res Opin 2015 0.75
134 Pharmacokinetic properties of single-dose lamivudine/adefovir dipivoxil fixed-dose combination in healthy Chinese male volunteers. Clin Ther 2012 0.75
135 Professor Philip Yu-An Ding 1949-2015. J Atheroscler Thromb 2016 0.75
136 Clinical outcome of hypertension management. J Med Econ 2008 0.75
137 OS 31-02 ANTIHYPERTENSIVE RESPONSE TO BISOPROLOL WAS NOT RELATED TO POLYMORPHISMS IN ADRB1 Or CYP2D6 IN CHINESE HYPERTENSIVE PATIENTS. J Hypertens 2016 0.75
138 CYP3A5 but not CYP2D6 polymorphism contributes significantly to the variability in dextropropoxyphene disposition. J Clin Pharmacol 2010 0.75
139 Inflammatory Burden Is Related to an Early Reduction of LV Functional Reserve in Psoriatic Arthritis. JACC Cardiovasc Imaging 2017 0.75
140 Management of Familial Hypercholesterolemia in Hong Kong. J Atheroscler Thromb 2016 0.75
141 Assessing the effectiveness of a Grand Rounds CME activity for health-care professionals. J Cancer Educ 2013 0.75
142 Effects of CYP2D6*10, CYP3A5*3, CYP1A2*1F, and ABCB1 C3435T polymorphisms on the pharmacokinetics of flecainide in healthy Chinese subjects. Drug Metabol Drug Interact 2012 0.75
143 Regulation of endothelin-1 production in deoxycorticosterone acetate- salt-treated endothelial cells. Pharmacology 2002 0.75
144 OS 31-02 ANTIHYPERTENSIVE RESPONSE TO BISOPROLOL WAS NOT RELATED TO POLYMORPHISMS IN ADRB1 Or CYP2D6 IN CHINESE HYPERTENSIVE PATIENTS. J Hypertens 2016 0.75
145 Relationship between obesity and cardiovascular risk factors in elderly Chinese subjects. Chin Med J (Engl) 2002 0.75
146 Effects of concomitant therapy with diltiazem on the lipid responses to simvastatin in Chinese subjects. J Clin Pharmacol 2010 0.75
147 Influence of CYP2C19 genotype on the pharmacokinetics of R483, a CYP2C19 substrate, in healthy subjects and type 2 diabetes patients. Eur J Clin Pharmacol 2010 0.75
148 Age-related anthropometric remodelling resulting in increased and redistributed adiposity is associated with increases in the prevalence of cardiovascular risk factors in Chinese subjects. Diabetes Metab Res Rev 2005 0.75
149 Pharmacokinetic evaluation of lanreotide. Expert Opin Drug Metab Toxicol 2010 0.75
150 Growth hormone-releasing factor agonists for the treatment of HIV-associated lipodystrophy. Curr Opin Investig Drugs 2010 0.75