Published in Biochem Biophys Res Commun on March 18, 2005
The seed and soil hypothesis revisited--the role of tumor-stroma interactions in metastasis to different organs. Int J Cancer (2011) 2.87
Interleukin-6 in bone metastasis and cancer progression. Eur J Cancer (2010) 2.04
Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases. Cancer Res (2012) 1.65
Differential expression of the RANKL/RANK/OPG system is associated with bone metastasis in human non-small cell lung cancer. PLoS One (2013) 1.64
Anoikis and survival connections in the tumor microenvironment: is there a role in prostate cancer metastasis? Cancer Res (2005) 1.39
Up-regulation of bone marrow stromal protein 2 (BST2) in breast cancer with bone metastasis. BMC Cancer (2009) 1.29
Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone. Clin Exp Metastasis (2008) 1.25
Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface. Cancer Res (2010) 1.21
Influence of simultaneous targeting of the bone morphogenetic protein pathway and RANK/RANKL axis in osteolytic prostate cancer lesion in bone. Bone (2008) 1.18
Cancer metastasis networks and the prediction of progression patterns. Br J Cancer (2009) 1.17
Integrin αv expression is required for the acquisition of a metastatic stem/progenitor cell phenotype in human prostate cancer. Am J Pathol (2011) 1.16
Therapeutic strategies targeting cancer stem cells. Cancer Sci (2015) 1.07
Proteases as modulators of tumor-stromal interaction: primary tumors to bone metastases. Biochim Biophys Acta (2007) 1.07
XPO1/CRM1-selective inhibitors of nuclear export (SINE) reduce tumor spreading and improve overall survival in preclinical models of prostate cancer (PCa). J Hematol Oncol (2014) 0.99
Tumor metastasis to bone. Arthritis Res Ther (2007) 0.98
The CXCR4-SDF1alpha axis is a critical mediator of rhabdomyosarcoma metastatic signaling induced by bone marrow stroma. Clin Exp Metastasis (2007) 0.95
Parathyroid hormone-related protein and ezrin are up-regulated in human lung cancer bone metastases. Clin Exp Metastasis (2007) 0.95
Homing of cancer cells to the bone. Cancer Microenviron (2011) 0.92
Flat-panel detector-based volume computed tomography: a novel 3D imaging technique to monitor osteolytic bone lesions in a mouse tumor metastasis model. Neoplasia (2007) 0.91
Erlotinib inhibits osteolytic bone invasion of human non-small-cell lung cancer cell line NCI-H292. Clin Exp Metastasis (2011) 0.90
TAK1-TAB2 signaling contributes to bone destruction by breast carcinoma cells. Mol Cancer Res (2011) 0.90
Establishment of a biomarker model for predicting bone metastasis in resected stage III non-small cell lung cancer. J Exp Clin Cancer Res (2012) 0.90
Involvement of cell-cell and cell-matrix interactions in bone destruction induced by metastatic MDA-MB-231 human breast cancer cells in nude mice. J Bone Miner Metab (2008) 0.89
The Role of Cancer Stem Cells in the Organ Tropism of Breast Cancer Metastasis: A Mechanistic Balance between the "Seed" and the "Soil"? Int J Breast Cancer (2011) 0.89
Bone sialoprotein and osteopontin in bone metastasis of osteotropic cancers. Crit Rev Oncol Hematol (2013) 0.88
Features and prognostic impact of distant metastasis in patients with stage IV lung adenocarcinoma harboring EGFR mutations: importance of bone metastasis. Clin Exp Metastasis (2014) 0.87
Osteocalcin: a pivotal mediator or an innocent bystander in energy metabolism? Nephrol Dial Transplant (2010) 0.87
Bosentan inhibits tumor vascularization and bone metastasis in an immunocompetent skin-fold chamber model of breast carcinoma cell metastasis. Clin Exp Metastasis (2006) 0.87
New mechanistic insights of integrin β1 in breast cancer bone colonization. Oncotarget (2015) 0.86
ABCC5 supports osteoclast formation and promotes breast cancer metastasis to bone. Breast Cancer Res (2012) 0.86
Extracellular proteolysis in transgenic mouse models of breast cancer. J Mammary Gland Biol Neoplasia (2007) 0.86
Secretion of MCP-1 and other paracrine factors in a novel tumor-bone coculture model. BMC Cancer (2009) 0.85
Override of the osteoclast defect in osteopontin-deficient mice by metastatic tumor growth in the bone. Am J Pathol (2006) 0.85
Parathyroid hormone-related protein expression, in combination with nodal status, predicts bone metastasis and prognosis of breast cancer patients. Exp Ther Med (2012) 0.84
Molecular regulation of bone marrow metastasis in prostate and breast cancer. Bone Marrow Res (2014) 0.84
Notch3 in human breast cancer cell lines regulates osteoblast-cancer cell interactions and osteolytic bone metastasis. Am J Pathol (2010) 0.84
Characterization of bone resorption in novel in vitro and in vivo models of oral squamous cell carcinoma. Oral Oncol (2012) 0.82
Both cell-surface and secreted CSF-1 expressed by tumor cells metastatic to bone can contribute to osteoclast activation. Exp Cell Res (2009) 0.82
The immunological contribution of NF-κB within the tumor microenvironment: a potential protective role of zinc as an anti-tumor agent. Biochim Biophys Acta (2011) 0.82
The Breast Cancer to Bone (B2B) Metastases Research Program: a multi-disciplinary investigation of bone metastases from breast cancer. BMC Cancer (2015) 0.81
Recent aspects for disseminated carcinomatosis of the bone marrow associated with gastric cancer: What has been done for the past, and what will be needed in future? World J Gastroenterol (2015) 0.81
A convenient clinically relevant model of human breast cancer bone metastasis. Clin Exp Metastasis (2007) 0.81
Intraoperative Near-infrared Fluorescence Imaging with Novel Indocyanine Green-Loaded Nanocarrier for Spinal Metastasis: A Preliminary Animal Study. Open Biomed Eng J (2012) 0.81
Cathepsin L inactivation leads to multimodal inhibition of prostate cancer cell dissemination in a preclinical bone metastasis model. Int J Cancer (2016) 0.80
Dihydroartemisinin prevents breast cancer-induced osteolysis via inhibiting both breast caner cells and osteoclasts. Sci Rep (2016) 0.80
Role of RANKL/RANK in primary and secondary breast cancer. World J Orthop (2013) 0.79
The role of the bone microenvironment in skeletal metastasis. J Bone Oncol (2012) 0.79
Role of RANKL (TNFSF11)-dependent osteopetrosis in the dental phenotype of Msx2 null mutant mice. PLoS One (2013) 0.78
Biological roles of human bone morphogenetic protein 9 in the bone microenvironment of human breast cancer MDA-MB-231 cells. Am J Transl Res (2015) 0.78
Behaviour of mesenchymal stem cells from bone marrow of untreated advanced breast and lung cancer patients without bone osteolytic metastasis. Clin Exp Metastasis (2012) 0.78
Mesenchymal stem cells regulate melanoma cancer cells extravasation to bone and liver at their perivascular niche. Int J Cancer (2015) 0.78
Immune mediators in the tumor microenvironment of prostate cancer. Chin J Cancer (2017) 0.78
Skeletal complications of ADT: disease burden and treatment options. Asian J Androl (2012) 0.77
Bone resorption facilitates osteoblastic bone metastatic colonization by cooperation of insulin-like growth factor and hypoxia. Cancer Sci (2014) 0.77
Cadherin-11 regulates the metastasis of Ewing sarcoma cells to bone. Clin Exp Metastasis (2015) 0.77
Does estrogen play a role in response to adjuvant bone-targeted therapies? J Bone Oncol (2013) 0.76
Low expression of BMPRIB indicates poor prognosis of breast cancer and is insensitive to taxane-anthracycline chemotherapy. Oncotarget (2016) 0.76
A tale of mice and (wo)men: development of and insights from an "all human" animal model of breast cancer metastasis to bone. Trans Am Clin Climatol Assoc (2012) 0.76
188Re-labelled gemcitabine/bisphosphonate (Gem/BP): a multi-functional, bone-specific agent as a potential treatment for bone metastases. Eur J Nucl Med Mol Imaging (2008) 0.76
Prostate cancer metastasis: roles of recruitment and reprogramming, cell signal network and three-dimensional growth characteristics. Transl Androl Urol (2015) 0.76
Src-signaling interference impairs the dissemination of blood-borne tumor cells. Cell Tissue Res (2012) 0.75
A promising approach for treatment of tumor-induced bone diseases: utilizing bisphosphonate derivatives of nucleoside antimetabolites. Bone (2010) 0.75
The SK-N-AS human neuroblastoma cell line develops osteolytic bone metastases with increased angiogenesis and COX-2 expression. J Bone Oncol (2014) 0.75
The role of macrophages in bone metastasis. J Bone Oncol (2013) 0.75
Osteocytes and Skeletal Pathophysiology. Curr Mol Biol Rep (2015) 0.75
Preclinical evaluation of sunitinib as a single agent in the prophylactic setting in a mouse model of bone metastases. BMC Cancer (2013) 0.75
Progress in the research on the mechanism of bone metastasis in lung cancer. Mol Clin Oncol (2016) 0.75
Bioengineering Models for Breast Cancer Research. Breast Cancer (Auckl) (2016) 0.75
Clinical significance of telomerase activity in peritoneal disseminated cells: gastrointestinal cancers. Mol Med (2008) 0.75
Dynamic live imaging of bone: opening a new era with 'bone histodynametry'. J Bone Miner Metab (2013) 0.75
Estrogen receptors in breast and bone: from virtue of remodeling to vileness of metastasis. Oncogene (2017) 0.75
Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. J Clin Invest (2004) 2.31
C-SRC tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis. Cancer Res (2003) 1.52
Zoledronic acid delays wound healing of the tooth extraction socket, inhibits oral epithelial cell migration, and promotes proliferation and adhesion to hydroxyapatite of oral bacteria, without causing osteonecrosis of the jaw, in mice. J Bone Miner Metab (2009) 1.29
The recovery of Mycobacterium avium-intracellulare complex (MAC) from the residential bathrooms of patients with pulmonary MAC. Clin Infect Dis (2007) 1.26
Cadherin-11-mediated interactions with bone marrow stromal/osteoblastic cells support selective colonization of breast cancer cells in bone. Int J Oncol (2008) 1.20
The effect of the bisphosphonate ibandronate on breast cancer metastasis to visceral organs. Breast Cancer Res Treat (2002) 1.15
Involvement of acidic microenvironment in the pathophysiology of cancer-associated bone pain. Bone (2010) 1.04
Regulation of osteoclast differentiation and function by phosphate: potential role of osteoclasts in the skeletal abnormalities in hypophosphatemic conditions. J Bone Miner Res (2007) 1.03
A synthetic peptide fragment of human MEPE stimulates new bone formation in vitro and in vivo. J Bone Miner Res (2003) 1.02
Acidic microenvironment created by osteoclasts causes bone pain associated with tumor colonization. J Bone Miner Metab (2007) 0.97
Ghrelin treatment of cachectic patients with chronic obstructive pulmonary disease: a multicenter, randomized, double-blind, placebo-controlled trial. PLoS One (2012) 0.96
Infective tricuspid valve endocarditis with pulmonary emboli caused by Campylobacter fetus after tooth extraction. Intern Med (2005) 0.96
Acid activation of Trpv1 leads to an up-regulation of calcitonin gene-related peptide expression in dorsal root ganglion neurons via the CaMK-CREB cascade: a potential mechanism of inflammatory pain. Mol Biol Cell (2010) 0.94
Immunohistochemical study of hard tissue formation in the rat pulp cavity after tooth replantation. Arch Oral Biol (2007) 0.90
Involvement of cell-cell and cell-matrix interactions in bone destruction induced by metastatic MDA-MB-231 human breast cancer cells in nude mice. J Bone Miner Metab (2008) 0.89
Acidosis and raised norepinephrine levels are associated with exercise dyspnoea in idiopathic pulmonary fibrosis. Respirology (2009) 0.85
Thy-1-positive cells in the subodontoblastic layer possess high potential to differentiate into hard tissue-forming cells. Histochem Cell Biol (2012) 0.84
Serodiagnosis of pulmonary disease due to Mycobacterium avium complex proven by bronchial wash culture. Chest (2010) 0.84
Alveolar bone regeneration of subcutaneously transplanted rat molar. Bone (2007) 0.83
1α,25-Dihydroxyvitamin D3 inhibits osteoblastic differentiation of mouse periodontal fibroblasts. Arch Oral Biol (2011) 0.83
Exertional dyspnea-related acidotic and sympathetic responses in patients with sequelae of pulmonary tuberculosis. J Physiol Sci (2010) 0.82
Localization of SUMOylation factors and Osterix in odontoblast lineage cells during dentin formation and regeneration. Histochem Cell Biol (2013) 0.81
[A case of spontaneous resolution of sarcoidosis with primary pulmonary cavitations]. Nihon Kokyuki Gakkai Zasshi (2007) 0.81
Effects of ghrelin treatment on exercise capacity in underweight COPD patients: a substudy of a multicenter, randomized, double-blind, placebo-controlled trial of ghrelin treatment. BMC Pulm Med (2013) 0.80
Identification of three exercise-induced mortality risk factors in patients with COPD. COPD (2014) 0.80
Effects of oxygen on exertional dyspnoea and exercise performance in patients with chronic obstructive pulmonary disease. Respirology (2012) 0.79
Localization of Thy-1-positive cells in the perichondrium during endochondral ossification. J Histochem Cytochem (2010) 0.79
Exercise-induced electrocardiographic changes in patients with chronic respiratory diseases: differential diagnosis by 99mTc-tetrofosmin SPECT. J Nucl Med (2003) 0.78
Enhanced bone-forming activity of side population cells in the periodontal ligament. Cell Transplant (2013) 0.78
Suppression by incadronate of invasion and growth of A-375 human melanoma in mandible in nude mice. Oncol Rep (2005) 0.78
Differences in physiological response to exercise in patients with different COPD severity. Respir Care (2013) 0.77
Prostaglandin E(2) receptor EP(4)-selective agonist (ONO-4819) increases bone formation by modulating mesenchymal cell differentiation. Eur J Pharmacol (2010) 0.77
Effects of tiotropium on sympathetic activation during exercise in stable chronic obstructive pulmonary disease patients. Int J Chron Obstruct Pulmon Dis (2012) 0.75
[Mechanism of cancer-induced bone pain]. Clin Calcium (2006) 0.75
[Direct detection of rifampicin resistant Mycobacterium tuberculosis in sputum by line probe assay (LiPA)]. Kekkaku (2004) 0.75
[Long-term care insurance eligibility in Japan for patients having home oxygen therapy]. Nihon Kokyuki Gakkai Zasshi (2003) 0.75
[A case of pneumonitis suspected to be induced by Oseltamivir]. Nihon Kokyuki Gakkai Zasshi (2006) 0.75
[Susceptibility to rifabutin and novel fluoroquinolones in Mycobacterium avium complex isolates from patients with sputum culture-positive pulmonary disease who are undergoing standard chemotherapy]. Nihon Kokyuki Gakkai Zasshi (2010) 0.75
The degree of exercise hypoxemia reflects pulmonary artery pressure during early exercise in chronic obstructive pulmonary disease patients. Clin Physiol Funct Imaging (2007) 0.75
Bisphosphonate actions on bone and visceral metastases. Cancer Treat Res (2004) 0.75
[Grading of officially acknowledged respiratory disability and exercise disorders using cardiopulmonary exercise testing in patients with chronic respiratory diseases]. Nihon Kokyuki Gakkai Zasshi (2004) 0.75