Chih-Chuan Liang

Author PubWeight™ 48.46‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice. Cardiovasc Res 2008 2.97
2 MicroRNAs: key participants in gene regulatory networks. Curr Opin Chem Biol 2003 2.28
3 Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction. Circulation 2007 1.88
4 Active chromatin hub of the mouse alpha-globin locus forms in a transcription factory of clustered housekeeping genes. Mol Cell Biol 2006 1.72
5 Paraoxonase gene polymorphisms, oxidative stress, and diseases. J Mol Med (Berl) 2003 1.57
6 SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages. J Biol Chem 2009 1.39
7 Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction. Circ Res 2011 1.32
8 Positive regulation of hepatic miR-122 expression by HNF4α. J Hepatol 2011 1.31
9 Increased efficiency of oligonucleotide-mediated gene repair through slowing replication fork progression. Proc Natl Acad Sci U S A 2005 1.26
10 Sirt1 deacetylates c-Myc and promotes c-Myc/Max association. Int J Biochem Cell Biol 2011 1.16
11 Modulations of hMOF autoacetylation by SIRT1 regulate hMOF recruitment and activities on the chromatin. Cell Res 2011 1.15
12 SIRT1 acts as a modulator of neointima formation following vascular injury in mice. Circ Res 2011 1.11
13 Isorhapontigenin, a new resveratrol analog, attenuates cardiac hypertrophy via blocking signaling transduction pathways. Free Radic Biol Med 2005 1.11
14 Epigallocathechin-3 gallate inhibits cardiac hypertrophy through blocking reactive oxidative species-dependent and -independent signal pathways. Free Radic Biol Med 2006 1.10
15 Exploring cellular memory molecules marking competent and active transcriptions. BMC Mol Biol 2007 0.96
16 A20 attenuates vascular smooth muscle cell proliferation and migration through blocking PI3k/Akt singling in vitro and in vivo. J Biomed Sci 2007 0.92
17 Human paraoxonase gene cluster transgenic overexpression represses atherogenesis and promotes atherosclerotic plaque stability in ApoE-null mice. Circ Res 2009 0.92
18 A20 inhibits oxidized low-density lipoprotein-induced apoptosis through negative Fas/Fas ligand-dependent activation of caspase-8 and mitochondrial pathways in murine RAW264.7 macrophages. J Cell Physiol 2006 0.91
19 Charting gene regulatory networks: strategies, challenges and perspectives. Biochem J 2004 0.90
20 A conserved, extended chromatin opening within alpha-globin locus during development. Exp Cell Res 2005 0.90
21 Retrovirus vector-mediated stable gene silencing in human cell. Biochem Biophys Res Commun 2004 0.90
22 KATP channel: relation with cell metabolism and role in the cardiovascular system. Int J Biochem Cell Biol 2005 0.89
23 Involvement of the p65/RelA subunit of NF-kappaB in TNF-alpha-induced SIRT1 expression in vascular smooth muscle cells. Biochem Biophys Res Commun 2010 0.89
24 Remembering the cell fate during cellular differentiation. J Cell Biochem 2005 0.87
25 Opening the chromatin for transcription. Int J Biochem Cell Biol 2004 0.87
26 The role of small RNAs in human diseases: potential troublemaker and therapeutic tools. Med Res Rev 2005 0.84
27 Memory mechanisms of active transcription during cell division. Bioessays 2005 0.83
28 Mechanisms of human gamma-globin transcriptional induction by apicidin involves p38 signaling to chromatin. Biochem Biophys Res Commun 2007 0.83
29 Chromatin structure and transcriptional regulation of the beta-globin locus. Exp Cell Res 2002 0.82
30 MafK/NF-E2 p18 is required for beta-globin genes activation by mediating the proximity of LCR and active beta-globin genes in MEL cell line. Int J Biochem Cell Biol 2007 0.81
31 SIRT1 deacetylates SATB1 to facilitate MAR HS2-MAR ε interaction and promote ε-globin expression. Nucleic Acids Res 2012 0.81
32 Knockdown of human p53 gene expression in 293-T cells by retroviral vector-mediated short hairpin RNA. Acta Biochim Biophys Sin (Shanghai) 2005 0.80
33 The control of expression of the alpha-globin gene cluster. Int J Hematol 2002 0.80
34 Regulation of human apolipoprotein B gene expression at multiple levels. Exp Cell Res 2003 0.80
35 Targeted correction of a chromosomal point mutation by modified single-stranded oligonucleotides in a GFP recovery system. Biochem Biophys Res Commun 2005 0.80
36 Unravelling the world of cis-regulatory elements. Med Biol Eng Comput 2007 0.79
37 Oligonucleotide-mediated gene repair at DNA level: the potential applications for gene therapy. J Mol Med (Berl) 2002 0.79
38 A general method to modify BACs to generate large recombinant DNA fragments. Mol Biotechnol 2005 0.78
39 No existence of translocus balancer to coordinate the expression and regulation of human hemoglobin genes in transgenic mice study. Int J Biochem Cell Biol 2004 0.78
40 Further understanding of the beta-globin locus regulation at the molecular level: looping or linking models? Genes Cells 2002 0.78
41 The apolipoprotein CIII enhancer regulates both extensive histone modification and intergenic transcription of human apolipoprotein AI/CIII/AIV genes but not apolipoprotein AV. J Biol Chem 2008 0.78
42 Improvement of SSO-mediated gene repair efficiency by nonspecific oligonucleotides. Biochem Biophys Res Commun 2008 0.77
43 Optimizing the delivery systems of chimeric RNA.DNA oligonucleotides. Eur J Biochem 2002 0.77
44 The impact of FISH on globin gene regulation research. Exp Cell Res 2003 0.77
45 Knockdown of mouse adult beta-globin gene expression in MEL cells by retrovirus vector-mediated RNA interference. Mol Biotechnol 2004 0.76
46 HS-48 alone has no enhancement role on the expression of human alpha-globin gene cluster. Blood Cells Mol Dis 2006 0.76
47 Endothelium-specific overexpression of human IC53 downregulates endothelial nitric oxide synthase activity and elevates systolic blood pressure in mice. Cardiovasc Res 2009 0.76
48 Identification of long range regulatory elements of mouse alpha-globin gene cluster by quantitative associated chromatin trap (QACT). J Cell Biochem 2008 0.76
49 Analysis of adeno-associated virus-mediated ex vivo transferred human beta-globin gene in bone marrow engrafted mice. J Biomed Sci 2002 0.75
50 High fidelity screening of regulatory sequences in apolipoprotein(a)-plasminogen cluster. Int J Biochem Cell Biol 2005 0.75
51 Cre-mediated site-specific cassette exchange in erythroid cell. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 2003 0.75
52 Efficient isolation of regulatory sequences from human genome and BAC DNA. Biochem Biophys Res Commun 2002 0.75
53 [The possible mechanisms underlying low expression of human beta-globin gene cloned in a retroviral vector]. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 2002 0.75
54 [Development of gene therapy for hematopoietic stem cell using viral vectors]. Yi Chuan Xue Bao 2003 0.75
55 Finding regulatory sequences. Int J Biochem Cell Biol 2003 0.75
56 Excessive expression of the scavenger receptor class A type I can significantly affect the serum lipids. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 2003 0.75
57 Evaluation of optimal expression cassette in retrovirus vector for beta-thalassemia gene therapy. Mol Biotechnol 2003 0.75
58 Screening regulatory sequences from bacterial artificial chromosome DNA of alpha- and beta-globin gene clusters. Biochem Cell Biol 2002 0.75
59 Insights into mechanism of NMD: digging from the NMD-related protein complexes. Curr Med Chem 2006 0.75