Cellular stress failure in ventilator-injured lungs.

PubWeight™: 1.44‹?› | Rank: Top 5%

🔗 View Article (PMC 2718477)

Published in Am J Respir Crit Care Med on February 01, 2005

Authors

Nicholas E Vlahakis1, Rolf D Hubmayr

Author Affiliations

1: Thoracic Diseases Research Unit, Division of Pulmonary and Critical care Medicine, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. vlahakis.nicholas@mayo.edu

Articles citing this

Animal models of acute lung injury. Am J Physiol Lung Cell Mol Physiol (2008) 6.10

Brief, large tidal volume ventilation initiates lung injury and a systemic response in fetal sheep. Am J Respir Crit Care Med (2007) 1.73

Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice. Am J Respir Crit Care Med (2007) 1.41

The physical basis of ventilator-induced lung injury. Expert Rev Respir Med (2010) 1.11

Recent advances and new opportunities in lung mechanobiology. J Biomech (2009) 1.06

Actin cytoskeleton regulates stretch-activated Ca2+ influx in human pulmonary microvascular endothelial cells. Am J Respir Cell Mol Biol (2009) 1.01

Inhaled activated protein C protects mice from ventilator-induced lung injury. Crit Care (2010) 1.00

Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury. Crit Care (2010) 1.00

Noninjurious mechanical ventilation activates a proinflammatory transcriptional program in the lung. Physiol Genomics (2009) 0.98

Cell wounding and repair in ventilator injured lungs. Respir Physiol Neurobiol (2008) 0.96

Lung parenchymal mechanics. Compr Physiol (2011) 0.96

Mechanical ventilation enhances lung inflammation and caspase activity in a model of mouse pneumovirus infection. Am J Physiol Lung Cell Mol Physiol (2008) 0.94

Stretch-induced activation of AMP kinase in the lung requires dystroglycan. Am J Respir Cell Mol Biol (2008) 0.91

Endocytic response of type I alveolar epithelial cells to hypertonic stress. Am J Physiol Lung Cell Mol Physiol (2011) 0.91

Biophysical determinants of alveolar epithelial plasma membrane wounding associated with mechanical ventilation. Am J Physiol Lung Cell Mol Physiol (2013) 0.91

Hypercapnia: a nonpermissive environment for the lung. Am J Respir Cell Mol Biol (2012) 0.91

Influence of Transmural Pressure and Cytoskeletal Structure on NF-κB Activation in Respiratory Epithelial Cells. Cell Mol Bioeng (2010) 0.90

Interactions between mechanical and biological processes in acute lung injury. Proc Am Thorac Soc (2008) 0.90

Lung-specific loss of the laminin α3 subunit confers resistance to mechanical injury. J Cell Sci (2011) 0.89

Impact of low and high tidal volumes on the rat alveolar epithelial type II cell proteome. Am J Respir Crit Care Med (2007) 0.87

The role of purinergic signaling on deformation induced injury and repair responses of alveolar epithelial cells. PLoS One (2011) 0.86

IL-10 inhibits inflammatory cytokines released by fetal mouse lung fibroblasts exposed to mechanical stretch. Pediatr Pulmonol (2011) 0.85

Role of the Fas/FasL system in a model of RSV infection in mechanically ventilated mice. Am J Physiol Lung Cell Mol Physiol (2011) 0.85

Poloxamer 188 facilitates the repair of alveolus resident cells in ventilator-injured lungs. Am J Respir Crit Care Med (2011) 0.84

Ropivacaine attenuates endotoxin plus hyperinflation-mediated acute lung injury via inhibition of early-onset Src-dependent signaling. BMC Anesthesiol (2014) 0.83

Beyond volutrauma in ARDS: the critical role of lung tissue deformation. Crit Care (2011) 0.83

A dystroglycan/plectin scaffold mediates mechanical pathway bifurcation in lung epithelial cells. J Biol Chem (2010) 0.83

Mechanical strain of alveolar type II cells in culture: changes in the transcellular cytokeratin network and adaptations. Am J Physiol Lung Cell Mol Physiol (2008) 0.82

Mechanobiology in lung epithelial cells: measurements, perturbations, and responses. Compr Physiol (2012) 0.80

TRIM72 is required for effective repair of alveolar epithelial cell wounding. Am J Physiol Lung Cell Mol Physiol (2014) 0.80

Acute respiratory distress syndrome and lung injury: Pathogenetic mechanism and therapeutic implication. World J Crit Care Med (2012) 0.80

The differential effects of inspiratory, expiratory, and combined resistive breathing on healthy lung. Int J Chron Obstruct Pulmon Dis (2016) 0.79

Alveolar type II cells escape stress failure caused by tonic stretch through transient focal adhesion disassembly. Int J Biol Sci (2011) 0.77

Computational analysis of microbubble flows in bifurcating airways: role of gravity, inertia, and surface tension. J Biomech Eng (2014) 0.77

TRIM72 modulates caveolar endocytosis in repair of lung cells. Am J Physiol Lung Cell Mol Physiol (2015) 0.77

Balancing between stiff and soft: a life-saving compromise for lung epithelium in lung injury. J Appl Physiol (1985) (2014) 0.77

Site-specific sonoporation of human melanoma cells at the cellular level using high lateral-resolution ultrasonic micro-transducer arrays. Biosens Bioelectron (2011) 0.77

Murine mechanical ventilation stimulates alveolar epithelial cell proliferation. Exp Lung Res (2010) 0.76

Acute lung injury and acute respiratory distress syndrome: experimental and clinical investigations. J Geriatr Cardiol (2011) 0.75

The impact of low-frequency, low-force cyclic stretching of human bronchi on airway responsiveness. Respir Res (2016) 0.75

Live Cell Imaging during Mechanical Stretch. J Vis Exp (2015) 0.75

Ventilator-induced Lung Injury. Clin Chest Med (2016) 0.75

Plasma membrane wounding and repair in pulmonary diseases. Am J Physiol Lung Cell Mol Physiol (2017) 0.75

Tiotropium bromide exerts anti-inflammatory effects during resistive breathing, an experimental model of severe airway obstruction. Int J Chron Obstruct Pulmon Dis (2017) 0.75

Articles cited by this

(truncated to the top 100)

Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med (2000) 48.03

Integrins: bidirectional, allosteric signaling machines. Cell (2002) 36.25

Lipid rafts and signal transduction. Nat Rev Mol Cell Biol (2000) 25.87

Transmembrane crosstalk between the extracellular matrix--cytoskeleton crosstalk. Nat Rev Mol Cell Biol (2001) 10.74

Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med (1998) 10.22

Structure and function of sphingolipid- and cholesterol-rich membrane rafts. J Biol Chem (2000) 9.96

Membrane fusion. Cell (2003) 7.68

Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proc Natl Acad Sci U S A (1997) 7.24

Defective membrane repair in dysferlin-deficient muscular dystrophy. Nature (2003) 6.50

Scaling the microrheology of living cells. Phys Rev Lett (2001) 6.32

Adhesion-dependent cell mechanosensitivity. Annu Rev Cell Dev Biol (2003) 6.08

Physical properties of the fluid lipid-bilayer component of cell membranes: a perspective. Q Rev Biophys (1991) 5.96

Endothelial contraction induced by histamine-type mediators: an electron microscopic study. J Cell Biol (1969) 5.79

Cytoskeletal regulation of pulmonary vascular permeability. J Appl Physiol (1985) (2001) 5.63

Ventilator-induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med (1998) 5.58

Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes. Cell (2001) 5.12

Caveolae: from cell biology to animal physiology. Pharmacol Rev (2002) 4.45

Stress distribution in lungs: a model of pulmonary elasticity. J Appl Physiol (1970) 4.38

Tensegrity I. Cell structure and hierarchical systems biology. J Cell Sci (2003) 4.36

Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J Clin Invest (1997) 4.00

The conformation of membranes. Nature (1991) 3.96

Cell membrane resealing by a vesicular mechanism similar to neurotransmitter release. Science (1994) 3.78

Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group. Am J Respir Crit Care Med (2003) 3.75

Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome. JAMA (2003) 3.69

Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures. Protection by positive end-expiratory pressure. Am Rev Respir Dis (1974) 3.66

Plasma membrane disruption: repair, prevention, adaptation. Annu Rev Cell Dev Biol (2003) 3.60

Mechanical behavior in living cells consistent with the tensegrity model. Proc Natl Acad Sci U S A (2001) 3.47

Lysosomes behave as Ca2+-regulated exocytic vesicles in fibroblasts and epithelial cells. J Cell Biol (1997) 3.31

Incidence and mortality after acute respiratory failure and acute respiratory distress syndrome in Sweden, Denmark, and Iceland. The ARF Study Group. Am J Respir Crit Care Med (1999) 3.28

Water permeability and mechanical strength of polyunsaturated lipid bilayers. Biophys J (2000) 3.16

Mechanotransduction at cell-matrix and cell-cell contacts. Annu Rev Biomed Eng (2004) 3.15

Tidal ventilation at low airway pressures can augment lung injury. Am J Respir Crit Care Med (1994) 3.13

The cytoskeleton and cell signaling: component localization and mechanical coupling. Physiol Rev (1998) 3.13

Critical role for CXCR2 and CXCR2 ligands during the pathogenesis of ventilator-induced lung injury. J Clin Invest (2002) 3.08

Multiple system organ failure. Is mechanical ventilation a contributing factor? Am J Respir Crit Care Med (1998) 2.96

Characteristics of a membrane reservoir buffering membrane tension. Biophys J (1999) 2.93

Cell control by membrane-cytoskeleton adhesion. Nat Rev Mol Cell Biol (2001) 2.91

Calcium-regulated exocytosis is required for cell membrane resealing. J Cell Biol (1995) 2.86

Role of integrins in endothelial mechanosensing of shear stress. Circ Res (2002) 2.85

Cell surface area regulation and membrane tension. J Membr Biol (2001) 2.75

Signal transduction by cell adhesion receptors and the cytoskeleton: functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members. Annu Rev Pharmacol Toxicol (2002) 2.62

Race and gender differences in acute respiratory distress syndrome deaths in the United States: an analysis of multiple-cause mortality data (1979- 1996). Crit Care Med (2002) 2.52

Mechanotransduction in response to shear stress. Roles of receptor tyrosine kinases, integrins, and Shc. J Biol Chem (1999) 2.51

Mechanotransduction through growth-factor shedding into the extracellular space. Nature (2004) 2.48

Modulation of the bilayer thickness of exocytic pathway membranes by membrane proteins rather than cholesterol. Proc Natl Acad Sci U S A (2004) 2.44

Mechanisms of surface-tension-induced epithelial cell damage in a model of pulmonary airway reopening. J Appl Physiol (1985) (2002) 2.43

Cell organization in soft media due to active mechanosensing. Proc Natl Acad Sci U S A (2003) 2.41

Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands. Proc Natl Acad Sci U S A (2001) 2.40

The resealing process of lipid bilayers after reversible electrical breakdown. Biochim Biophys Acta (1981) 2.35

Dynamic tension spectroscopy and strength of biomembranes. Biophys J (2003) 2.35

Regulated secretion of conventional lysosomes. Trends Cell Biol (2000) 2.34

Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases. J Biol Chem (1997) 2.34

Ventilator-induced lung injury leads to loss of alveolar and systemic compartmentalization of tumor necrosis factor-alpha. Intensive Care Med (2000) 2.33

Control of cytoskeletal mechanics by extracellular matrix, cell shape, and mechanical tension. Biophys J (1994) 2.32

Cell mechanics and mechanotransduction: pathways, probes, and physiology. Am J Physiol Cell Physiol (2004) 2.32

Invited review: mechanisms of ventilator-induced lung injury: a perspective. J Appl Physiol (1985) (2000) 2.28

Incidence and mortality of acute lung injury and the acute respiratory distress syndrome in three Australian States. Am J Respir Crit Care Med (2002) 2.28

Kinesin- and myosin-driven steps of vesicle recruitment for Ca2+-regulated exocytosis. J Cell Biol (1997) 2.23

Pathogenesis of high-altitude pulmonary edema: inflammation is not an etiologic factor. JAMA (2002) 2.23

Dealing with mechanics: mechanisms of force transduction in cells. Trends Biochem Sci (2004) 2.23

Opposing views on tensegrity as a structural framework for understanding cell mechanics. J Appl Physiol (1985) (2000) 2.19

Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis. J Biol Chem (2004) 2.17

Ventilator-induced injury: from barotrauma to biotrauma. Proc Assoc Am Physicians (1999) 2.13

Impaired membrane resealing and autoimmune myositis in synaptotagmin VII-deficient mice. J Cell Biol (2003) 2.12

A theoretical model study of the influence of fluid stresses on a cell adhering to a microchannel wall. Biophys J (1998) 2.12

Improved survival of patients with acute respiratory distress syndrome (ARDS): 1983-1993. JAMA (1995) 2.12

Phosphoinositides, key molecules for regulation of actin cytoskeletal organization and membrane traffic from the plasma membrane. Biochim Biophys Acta (2001) 2.09

Positive end-expiratory pressure after a recruitment maneuver prevents both alveolar collapse and recruitment/derecruitment. Am J Respir Crit Care Med (2003) 2.06

Calcium mobilization and exocytosis after one mechanical stretch of lung epithelial cells. Science (1990) 2.05

Early changes in lung gene expression due to high tidal volume. Am J Respir Crit Care Med (2003) 2.03

Large plasma membrane disruptions are rapidly resealed by Ca2+-dependent vesicle-vesicle fusion events. J Cell Biol (1997) 2.01

Deformation-induced injury of alveolar epithelial cells. Effect of frequency, duration, and amplitude. Am J Respir Crit Care Med (2000) 1.99

Ventilator-induced cell wounding and repair in the intact lung. Am J Respir Crit Care Med (2002) 1.97

Patching plasma membrane disruptions with cytoplasmic membrane. J Cell Sci (2000) 1.96

Alveolar epithelial surface area-volume relationship in isolated rat lungs. J Appl Physiol (1985) (1999) 1.95

The mechanism of facilitated cell membrane resealing. J Cell Sci (1999) 1.93

Lipid rafts and plasma membrane microorganization: insights from Ras. Trends Cell Biol (2004) 1.92

Intermittent positive-pressure hyperventilation with high inflation pressures produces pulmonary microvascular injury in rats. Am Rev Respir Dis (1985) 1.92

Mechanical ventilation affects local and systemic cytokines in an animal model of acute respiratory distress syndrome. Am J Respir Crit Care Med (1999) 1.90

Stretch induces cytokine release by alveolar epithelial cells in vitro. Am J Physiol (1999) 1.89

A new self-assembled peroxisomal vesicle required for efficient resealing of the plasma membrane. Nat Cell Biol (2000) 1.89

Activation of human macrophages by mechanical ventilation in vitro. Am J Physiol (1998) 1.85

The endomembrane requirement for cell surface repair. Proc Natl Acad Sci U S A (2003) 1.85

Clathrin-dependent or not: is it still the question? Traffic (2002) 1.85

On the physiologic and clinical relevance of lung-borne cytokines during ventilator-induced lung injury. Am J Respir Crit Care Med (2003) 1.84

Prone positioning attenuates and redistributes ventilator-induced lung injury in dogs. Crit Care Med (2000) 1.83

Alveolar volume-surface area relation in air- and saline-filled lungs fixed by vascular perfusion. J Appl Physiol Respir Environ Exerc Physiol (1979) 1.77

Equibiaxial deformation-induced injury of alveolar epithelial cells in vitro. Am J Physiol (1998) 1.74

Science review: mechanisms of ventilator-induced injury. Crit Care (2002) 1.71

Perspective on lung injury and recruitment: a skeptical look at the opening and collapse story. Am J Respir Crit Care Med (2002) 1.71

Pressure-volume curve of total respiratory system in acute respiratory failure. Computed tomographic scan study. Am Rev Respir Dis (1987) 1.66

Spatial distribution of ventilation and perfusion in anesthetized dogs in lateral postures. J Appl Physiol (1985) (2002) 1.66

Gastrointestinal cell plasma membrane wounding and resealing in vivo. Gastroenterology (1989) 1.65

A decrease in membrane tension precedes successful cell-membrane repair. Mol Biol Cell (2000) 1.64

Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress. J Clin Invest (1999) 1.62

Regulated exocytosis: a novel, widely expressed system. Nat Cell Biol (2002) 1.61

Nonmuscle myosin IIA and IIB have distinct functions in the exocytosis-dependent process of cell membrane repair. Mol Biol Cell (2003) 1.59

Mechanical stressing of integrin receptors induces enhanced tyrosine phosphorylation of cytoskeletally anchored proteins. J Biol Chem (1998) 1.58

Ca2+-dependent exocytotic pathways in Chinese hamster ovary fibroblasts revealed by a caged-Ca2+ compound. J Biol Chem (1996) 1.58

Stretch-regulated exocytosis/endocytosis in bladder umbrella cells. Mol Biol Cell (2002) 1.56

Articles by these authors

Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation. Crit Care Med (2004) 5.32

Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group. Am J Respir Crit Care Med (2003) 3.75

Transfusion-related acute lung injury in the critically ill: prospective nested case-control study. Am J Respir Crit Care Med (2007) 3.69

Introduction of a 14-hour work shift model for housestaff in the medical ICU. Chest (2005) 3.66

Ventilator settings as a risk factor for acute respiratory distress syndrome in mechanically ventilated patients. Intensive Care Med (2005) 3.32

The Stability and Workload Index for Transfer score predicts unplanned intensive care unit patient readmission: initial development and validation. Crit Care Med (2008) 3.14

Eight-year trend of acute respiratory distress syndrome: a population-based study in Olmsted County, Minnesota. Am J Respir Crit Care Med (2010) 3.10

Effect of 24-hour mandatory versus on-demand critical care specialist presence on quality of care and family and provider satisfaction in the intensive care unit of a teaching hospital. Crit Care Med (2008) 3.04

Silver-coated endotracheal tubes and incidence of ventilator-associated pneumonia: the NASCENT randomized trial. JAMA (2008) 3.01

Association between ICU admission during morning rounds and mortality. Chest (2009) 2.98

Toward the prevention of acute lung injury: protocol-guided limitation of large tidal volume ventilation and inappropriate transfusion. Crit Care Med (2007) 2.72

Risk factors for the development of acute lung injury in patients with septic shock: an observational cohort study. Crit Care Med (2008) 2.68

Intraoperative tidal volume as a risk factor for respiratory failure after pneumonectomy. Anesthesiology (2006) 2.64

Fresh red blood cell transfusion and short-term pulmonary, immunologic, and coagulation status: a randomized clinical trial. Am J Respir Crit Care Med (2012) 2.47

Evidence-based red cell transfusion in the critically ill: quality improvement using computerized physician order entry. Crit Care Med (2006) 2.44

Ventilator settings and outcome of respiratory failure in chronic interstitial lung disease. Chest (2007) 2.34

Validation of an electronic surveillance system for acute lung injury. Intensive Care Med (2009) 2.27

Evaluating the performance of an institution using an intensive care unit benchmark. Mayo Clin Proc (2005) 2.13

Fresh-frozen plasma and platelet transfusions are associated with development of acute lung injury in critically ill medical patients. Chest (2007) 2.11

Extravascular lung water and pulmonary vascular permeability index as markers predictive of postoperative acute respiratory distress syndrome: a prospective cohort investigation. Crit Care Med (2015) 2.05

Ventilator-induced cell wounding and repair in the intact lung. Am J Respir Crit Care Med (2002) 1.97

B-type natriuretic peptide in the assessment of acute lung injury and cardiogenic pulmonary edema. Crit Care Med (2006) 1.85

Limiting ventilator-induced lung injury through individual electronic medical record surveillance. Crit Care Med (2011) 1.74

The effects of the alveolar recruitment maneuver and positive end-expiratory pressure on arterial oxygenation during laparoscopic bariatric surgery. Anesth Analg (2006) 1.73

Failure of non-invasive ventilation in patients with acute lung injury: observational cohort study. Crit Care (2006) 1.71

Six-month survival of patients with acute lung injury: prospective cohort study. Crit Care Med (2007) 1.69

The influence of missing components of the Acute Physiology Score of APACHE III on the measurement of ICU performance. Intensive Care Med (2005) 1.66

Volume Delivered During Recruitment Maneuver Predicts Lung Stress in Acute Respiratory Distress Syndrome. Crit Care Med (2016) 1.57

Comparison of community and referral intensive care unit patients in a tertiary medical center: evidence for referral bias in the critically ill. Crit Care Med (2008) 1.52

Should we "rescue" patients with 2009 influenza A(H1N1) and lung injury from conventional mechanical ventilation? Chest (2010) 1.52

Pulmonary edema after transfusion: how to differentiate transfusion-associated circulatory overload from transfusion-related acute lung injury. Crit Care Med (2006) 1.49

Bronchoscopy in ventilator-associated pneumonia: agreement of calibrated loop and serial dilution. Am J Respir Crit Care Med (2006) 1.47

The hemodynamic effects of prone positioning in patients with acute respiratory distress syndrome remain to be defined. Am J Respir Crit Care Med (2014) 1.34

The impact of morbid obesity, pneumoperitoneum, and posture on respiratory system mechanics and oxygenation during laparoscopy. Anesth Analg (2002) 1.28

Risk factors and outcomes in transfusion-associated circulatory overload. Am J Med (2013) 1.21

Role of deformation-induced lipid trafficking in the prevention of plasma membrane stress failure. Am J Respir Crit Care Med (2002) 1.21

Acute lung injury after blood transfusion in mechanically ventilated patients. Transfusion (2004) 1.20

MR elastography of the lung with hyperpolarized 3He. Magn Reson Med (2008) 1.17

Hypercapnic acidosis impairs plasma membrane wound resealing in ventilator-injured lungs. Am J Respir Crit Care Med (2005) 1.15

Prospective study on the clinical course and outcomes in transfusion-related acute lung injury*. Crit Care Med (2014) 1.11

The physical basis of ventilator-induced lung injury. Expert Rev Respir Med (2010) 1.11

Bedside quantification of dead-space fraction using routine clinical data in patients with acute lung injury: secondary analysis of two prospective trials. Crit Care (2010) 1.10

Prediction of death and prolonged mechanical ventilation in acute lung injury. Crit Care (2007) 1.07

The Leukocyte Antibody Prevalence Study-II (LAPS-II): a retrospective cohort study of transfusion-related acute lung injury in recipients of high-plasma-volume human leukocyte antigen antibody-positive or -negative components. Transfusion (2011) 1.02

Liberal vs. conservative vasopressor use to maintain mean arterial blood pressure during resuscitation of septic shock: an observational study. Intensive Care Med (2007) 1.01

Determinants of plasma membrane wounding by deforming stress. Am J Physiol Lung Cell Mol Physiol (2010) 1.01

Impact of buffering hypercapnic acidosis on cell wounding in ventilator-injured rat lungs. Am J Physiol Lung Cell Mol Physiol (2008) 1.01

Impact of introducing multiple evidence-based clinical practice protocols in a medical intensive care unit: a retrospective cohort study. BMC Emerg Med (2007) 0.98

Delayed hypersensitivity reaction and acute respiratory distress syndrome following infliximab infusion. Inflamm Bowel Dis (2002) 0.97

MR elastography of human lung parenchyma: technical development, theoretical modeling and in vivo validation. J Magn Reson Imaging (2011) 0.96

Cell wounding and repair in ventilator injured lungs. Respir Physiol Neurobiol (2008) 0.96

Response of alveolar cells to mechanical stress. Curr Opin Crit Care (2003) 0.93

Spatiotemporal dynamics of actin remodeling and endomembrane trafficking in alveolar epithelial type I cell wound healing. Am J Physiol Lung Cell Mol Physiol (2011) 0.93

New insights into the pathology of acute respiratory failure. Curr Opin Crit Care (2005) 0.92

Endocytic response of type I alveolar epithelial cells to hypertonic stress. Am J Physiol Lung Cell Mol Physiol (2011) 0.91

Biophysical determinants of alveolar epithelial plasma membrane wounding associated with mechanical ventilation. Am J Physiol Lung Cell Mol Physiol (2013) 0.91

Hypercapnia: a nonpermissive environment for the lung. Am J Respir Cell Mol Biol (2012) 0.91

Sizing the lung of mechanically ventilated patients. Crit Care (2011) 0.91

Tracheostomy in critically ill patients. Mayo Clin Proc (2005) 0.91

Type I alveolar epithelial phenotype in primary culture. Am J Respir Cell Mol Biol (2010) 0.91

CrossTalk opposing view: there is not added benefit to providing permissive hypercapnia in the treatment of ARDS. J Physiol (2013) 0.89

Magnetic resonance assessment of parenchymal elasticity in normal and edematous, ventilator-injured lung. J Appl Physiol (1985) (2012) 0.89

A prospective trial of elective extubation in brain injured patients meeting extubation criteria for ventilatory support: a feasibility study. Crit Care (2008) 0.89

Temporal trends of ventilator-associated pneumonia incidence and the effect of implementing health-care bundles in a suburban community. Chest (2013) 0.88

Will the electronic medical record live up to its promise? Am J Respir Crit Care Med (2010) 0.88

Experimental models to study cell wounding and repair. Cell Physiol Biochem (2009) 0.88

Magnetic resonance elastography of the lung parenchyma in an in situ porcine model with a noninvasive mechanical driver: correlation of shear stiffness with trans-respiratory system pressures. Magn Reson Med (2011) 0.87

Feasibility of quantifying the mechanical properties of lung parenchyma in a small-animal model using (1)H magnetic resonance elastography (MRE). J Magn Reson Imaging (2009) 0.86

Respiratory monitoring tools in the intensive care unit. Curr Opin Crit Care (2003) 0.86

The role of purinergic signaling on deformation induced injury and repair responses of alveolar epithelial cells. PLoS One (2011) 0.86

The initial Mayo Clinic experience using high-frequency oscillatory ventilation for adult patients: a retrospective study. BMC Emerg Med (2006) 0.86

Poloxamer 188 facilitates the repair of alveolus resident cells in ventilator-injured lungs. Am J Respir Crit Care Med (2011) 0.84

Alveolar microstrain and the dark side of the lung. Crit Care (2007) 0.83

Plasma membrane stress failure in ventilator-injured lungs. A hypothesis about osmoregulation and the pharmacologic protection of the lungs against deformation injury. Biol Neonate (2004) 0.83

Estimation of the absolute shear stiffness of human lung parenchyma using (1) H spin echo, echo planar MR elastography. J Magn Reson Imaging (2013) 0.83

Diaphragm muscle shortening modulates kinematics of lower rib cage in dogs. Am J Physiol Regul Integr Comp Physiol (2010) 0.80

Should mechanical ventilation be guided by esophageal pressure measurements? Curr Opin Crit Care (2011) 0.79

Another look at the opening and collapse story. Crit Care Med (2009) 0.79

Is there a place for esophageal manometry in the care of patients with injured lungs? J Appl Physiol (1985) (2010) 0.79

Inhaled carbon monoxide attenuates myocardial inflammatory cytokine expression in a rat model of cardiopulmonary bypass. J Extra Corpor Technol (2011) 0.78

Dopamine inhibits pulmonary edema through the VEGF-VEGFR2 axis in a murine model of acute lung injury. Am J Physiol Lung Cell Mol Physiol (2011) 0.78

Diaphragm curvature modulates the relationship between muscle shortening and volume displacement. Am J Physiol Regul Integr Comp Physiol (2011) 0.77

The times are a-changin': should we hang up the stethoscope? Anesthesiology (2004) 0.77

Ventilator-induced lung injury without biotrauma? J Appl Physiol (1985) (2005) 0.76

Rebuttal from Jeremy R. Beitler, Rolf D. Hubmayr and Atul Malhotra. J Physiol (2013) 0.76

Lung stress and strain in acute respiratory distress syndrome: good ideas for clinical management? Am J Respir Crit Care Med (2008) 0.76

Regenerative medicine: why does it matter? Physiology (Bethesda) (2013) 0.75

Does oxygen tune cellular mechanotransduction? Am J Physiol Lung Cell Mol Physiol (2012) 0.75

Epithelial to mesenchymal transition: a new twist to biotrauma?. Crit Care Med (2012) 0.75

Straining to make mechanical ventilation safe and simple. Am J Respir Crit Care Med (2011) 0.75

Determination of infection probability versus the diagnosis and treatment of antibiotic-responsive diseases. Crit Care Med (2003) 0.75

Interpretation of airway pressure waveforms. Intensive Care Med (2006) 0.75

Understanding lung protection. Intensive Care Med (2015) 0.75