1
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Interactions of heparin/heparan sulfate with proteins: appraisal of structural factors and experimental approaches.
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Glycobiology
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2004
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1.83
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2
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Modular synthesis of heparan sulfate oligosaccharides for structure-activity relationship studies.
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J Am Chem Soc
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2009
|
1.72
|
3
|
Identification of the heparan sulfate binding sites in the cellular prion protein.
|
J Biol Chem
|
2002
|
1.41
|
4
|
A molecular mechanism for the heparan sulfate dependence of slit-robo signaling.
|
J Biol Chem
|
2006
|
1.37
|
5
|
Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2.
|
J Biol Chem
|
2005
|
1.36
|
6
|
Fabrication of carbohydrate microarrays on gold surfaces: direct attachment of nonderivatized oligosaccharides to hydrazide-modified self-assembled monolayers.
|
Anal Chem
|
2006
|
1.24
|
7
|
Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling.
|
Glycobiology
|
2002
|
1.18
|
8
|
Specific heparan sulfate structures modulate FGF10-mediated submandibular gland epithelial morphogenesis and differentiation.
|
J Biol Chem
|
2008
|
1.14
|
9
|
Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's beta-secretase.
|
J Cell Biol
|
2003
|
1.11
|
10
|
Extracellular regulation of developmental cell signaling by XtSulf1.
|
Dev Biol
|
2008
|
1.10
|
11
|
Specific heparan sulfate structures involved in retinal axon targeting.
|
Development
|
2002
|
1.09
|
12
|
Heparan 2-O-sulfotransferase, hst-2, is essential for normal cell migration in Caenorhabditis elegans.
|
Proc Natl Acad Sci U S A
|
2005
|
1.09
|
13
|
A versatile gold surface approach for fabrication and interrogation of glycoarrays.
|
Chembiochem
|
2008
|
1.08
|
14
|
Fibroblast growth factor receptors 1 and 2 interact differently with heparin/heparan sulfate. Implications for dynamic assembly of a ternary signaling complex.
|
J Biol Chem
|
2002
|
1.07
|
15
|
Rapid purification and high sensitivity analysis of heparan sulfate from cells and tissues: toward glycomics profiling.
|
J Biol Chem
|
2009
|
1.06
|
16
|
Heparan sulfate phage display antibodies identify distinct epitopes with complex binding characteristics: insights into protein binding specificities.
|
J Biol Chem
|
2009
|
1.05
|
17
|
The heparan sulfate motif (GlcNS6S-IdoA2S)3, common in heparin, has a strict topography and is involved in cell behavior and disease.
|
J Biol Chem
|
2010
|
1.03
|
18
|
Synthesis of a targeted library of heparan sulfate hexa- to dodecasaccharides as inhibitors of β-secretase: potential therapeutics for Alzheimer's disease.
|
Chemistry
|
2013
|
1.02
|
19
|
Novel mechanisms of fibroblast growth factor receptor 1 regulation by extracellular matrix protein anosmin-1.
|
J Biol Chem
|
2009
|
1.01
|
20
|
Software tool for the structural determination of glycosaminoglycans by mass spectrometry.
|
Anal Chem
|
2008
|
0.95
|
21
|
Generating heparan sulfate saccharide libraries for glycomics applications.
|
Nat Protoc
|
2010
|
0.95
|
22
|
Disaccharide compositional analysis of heparan sulfate and heparin polysaccharides using UV or high-sensitivity fluorescence (BODIPY) detection.
|
Nat Protoc
|
2010
|
0.94
|
23
|
Labelling heparan sulphate saccharides with chromophore, fluorescence and mass tags for HPLC and MS separations.
|
Methods Mol Biol
|
2009
|
0.93
|
24
|
Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships.
|
Org Biomol Chem
|
2010
|
0.92
|
25
|
Influence of substitution pattern and cation binding on conformation and activity in heparin derivatives.
|
Glycobiology
|
2007
|
0.91
|
26
|
Towards GAG glycomics: analysis of highly sulfated heparins by MALDI-TOF mass spectrometry.
|
Glycobiology
|
2007
|
0.90
|
27
|
Heparin derivatives as inhibitors of BACE-1, the Alzheimer's beta-secretase, with reduced activity against factor Xa and other proteases.
|
J Med Chem
|
2006
|
0.90
|
28
|
Saccharide microarrays for high-throughput interrogation of glycan-protein binding interactions.
|
Methods Mol Biol
|
2009
|
0.89
|
29
|
Highly diverse heparan sulfate analogue libraries: providing access to expanded areas of sequence space for bioactivity screening.
|
J Med Chem
|
2004
|
0.89
|
30
|
Disruption of rosetting in Plasmodium falciparum malaria with chemically modified heparin and low molecular weight derivatives possessing reduced anticoagulant and other serine protease inhibition activities.
|
J Med Chem
|
2008
|
0.87
|
31
|
The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids.
|
Thromb Haemost
|
2009
|
0.85
|
32
|
The activities of heparan sulfate and its analogue heparin are dictated by biosynthesis, sequence, and conformation.
|
Connect Tissue Res
|
2008
|
0.83
|
33
|
Heparan sulfate in lung morphogenesis: The elephant in the room.
|
Birth Defects Res C Embryo Today
|
2010
|
0.82
|
34
|
Array-based functional screening of heparin glycans.
|
Chem Biol
|
2012
|
0.82
|
35
|
Structure and epitope distribution of heparan sulfate is disrupted in experimental lung hypoplasia: a glycobiological epigenetic cause for malformation?
|
BMC Dev Biol
|
2011
|
0.82
|
36
|
Heparan sulfotransferases Hs6st1 and Hs2st keep Erk in check for mouse corpus callosum development.
|
J Neurosci
|
2014
|
0.81
|
37
|
Attachment of glycosaminoglycan oligosaccharides to thiol-derivatised gold surfaces.
|
Chem Commun (Camb)
|
2004
|
0.81
|
38
|
Proteoglycans make the grade-ient.
|
Mol Cell
|
2004
|
0.80
|
39
|
An expression system for screening of proteins for glycan and protein interactions.
|
Anal Biochem
|
2011
|
0.80
|
40
|
Differential sulfation remodelling of heparan sulfate by extracellular 6-O-sulfatases regulates fibroblast growth factor-induced boundary formation by glial cells: implications for glial cell transplantation.
|
J Neurosci
|
2012
|
0.80
|
41
|
The geometric control of E14 and R1 mouse embryonic stem cell pluripotency by plasma polymer surface chemical gradients.
|
Biomaterials
|
2008
|
0.79
|
42
|
Heparan sulfate phage display antibodies recognise epitopes defined by a combination of sugar sequence and cation binding.
|
Org Biomol Chem
|
2015
|
0.78
|
43
|
Cations modulate polysaccharide structure to determine FGF-FGFR signaling: a comparison of signaling and inhibitory polysaccharide interactions with FGF-1 in solution.
|
Biochemistry
|
2009
|
0.78
|
44
|
Engineered bio-active polysaccharides from heparin.
|
Macromol Biosci
|
2006
|
0.77
|
45
|
Single-entity heparan sulfate glycomimetic clusters for therapeutic applications.
|
Angew Chem Int Ed Engl
|
2015
|
0.76
|
46
|
Glycomics: technologies taming a frontier omics field.
|
OMICS
|
2010
|
0.76
|
47
|
Synthetic sugars enhance the functional glycomics toolkit.
|
Nat Chem Biol
|
2006
|
0.75
|
48
|
Panels of chemically-modified heparin polysaccharides and natural heparan sulfate saccharides both exhibit differences in binding to Slit and Robo, as well as variation between protein binding and cellular activity.
|
Mol Biosyst
|
2016
|
0.75
|
49
|
Heparin Isomeric Oligosaccharide Separation Using Volatile Salt Strong Anion Exchange Chromatography.
|
Anal Chem
|
2016
|
0.75
|
50
|
Enrichment of Two Isomeric Heparin Oligosaccharides Exhibiting Different Affinities toward Monocyte Chemoattractant Protein-1.
|
Anal Chem
|
2016
|
0.75
|