Published in J Biol Chem on February 04, 2005
VEGF targets the tumour cell. Nat Rev Cancer (2013) 2.71
Neuropilin-1 is a receptor for transforming growth factor beta-1, activates its latent form, and promotes regulatory T cell activity. J Leukoc Biol (2008) 1.72
Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF/SF autocrine pathway. Oncogene (2007) 1.71
Glycosaminoglycan modification of neuropilin-1 modulates VEGFR2 signaling. EMBO J (2006) 1.45
Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity. Oncotarget (2012) 1.37
Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A. Blood (2006) 1.25
NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis. Blood (2013) 1.21
Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells. Biochem J (2010) 1.07
Targeting neuropilin-1 in human leukemia and lymphoma. Blood (2010) 1.03
Semaphorins and their receptors in lung cancer. Cancer Lett (2008) 1.02
Function of members of the neuropilin family as essential pleiotropic cell surface receptors. Biochemistry (2012) 0.99
Neuropilins: expression and roles in the epithelium. Int J Exp Pathol (2012) 0.98
Neuropilin ligands in vascular and neuronal patterning. Biochem Soc Trans (2009) 0.95
Secreted factors as synaptic organizers. Eur J Neurosci (2010) 0.94
Neurovascular development and links to disease. Cell Mol Life Sci (2013) 0.92
Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A). PLoS Pathog (2013) 0.91
The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor. Cell Commun Signal (2010) 0.91
Neuropilins: a new target for cancer therapy. Cancers (Basel) (2011) 0.90
Exogenous recombinant dimeric neuropilin-1 is sufficient to drive angiogenesis. J Biol Chem (2010) 0.86
The emerging role of class-3 semaphorins and their neuropilin receptors in oncology. Onco Targets Ther (2014) 0.86
Neuropilin-2 promotes branching morphogenesis in the mouse mammary gland. Development (2011) 0.84
Neuropilin-1 as Therapeutic Target for Malignant Melanoma. Front Oncol (2015) 0.83
NRP1 function and targeting in neurovascular development and eye disease. Prog Retin Eye Res (2016) 0.82
Functional relevance of the switch of VEGF receptors/co-receptors during peritoneal dialysis-induced mesothelial to mesenchymal transition. PLoS One (2013) 0.81
Inhibition of tumor cell migration by LD22-4, an N-terminal fragment of 24-kDa FGF2, is mediated by Neuropilin 1. Cancer Res (2013) 0.80
Regulation of soluble neuropilin 1, an endogenous angiogenesis inhibitor, in liver development and regeneration. Pathology (2014) 0.79
Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars. PeerJ (2014) 0.79
Neuropilins 1 and 2 mediate neointimal hyperplasia and re-endothelialization following arterial injury. Cardiovasc Res (2015) 0.79
Lymphangiogenesis and metastasis--a closer look at the neuropilin/semaphorin3 axis. Microvasc Res (2014) 0.78
Neuropilin Functions as an Essential Cell Surface Receptor. J Biol Chem (2015) 0.78
Neuropilin-1 is a receptor for extracellular miRNA and AGO2/miRNA complexes and mediates the internalization of miRNAs that modulate cell function. Oncotarget (2016) 0.76
Control of cellular motility by neuropilin-mediated physical interactions. Biomol Concepts (2014) 0.76
Specific Neuropilins Expression in Alveolar Macrophages among Tissue-Specific Macrophages. PLoS One (2016) 0.75
A Sema3C Mutant Resistant to Cleavage by Furin (FR-Sema3C) Inhibits Choroidal Neovascularization. PLoS One (2016) 0.75
Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide. Oncotarget (2016) 0.75
Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma. Oncotarget (2016) 0.75
Neuropilin-1 in transplantation tolerance. Front Immunol (2013) 0.75
The role of the semaphorins in cancer. Cell Adh Migr (2016) 0.75
Regulation of RhoA activity by the cellular prion protein. Cell Death Dis (2017) 0.75
Neuropilins and liver. World J Gastroenterol (2015) 0.75
A Novel Physiological Glycosaminoglycan-Deficient Splice Variant of Neuropilin-1 Is Anti-Tumorigenic In Vitro and In Vivo. PLoS One (2016) 0.75
NRP1 transport of cancer therapeutics mediated by tumor-penetrating peptides. Drugs Future (2017) 0.75
Determination of size and concentration of gold nanoparticles from UV-vis spectra. Anal Chem (2007) 3.55
FGFs, their receptors, and human limb malformations: clinical and molecular correlations. Am J Med Genet (2002) 2.51
Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood (2007) 2.21
Interactions of heparin/heparan sulfate with proteins: appraisal of structural factors and experimental approaches. Glycobiology (2004) 1.83
Transport of fibroblast growth factor 2 in the pericellular matrix is controlled by the spatial distribution of its binding sites in heparan sulfate. PLoS Biol (2012) 1.79
Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication. Cell Host Microbe (2011) 1.74
Modular synthesis of heparan sulfate oligosaccharides for structure-activity relationship studies. J Am Chem Soc (2009) 1.72
Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors. Proc Natl Acad Sci U S A (2003) 1.62
Novel approach to inhibit asthma-mediated lung inflammation using anti-CD147 intervention. J Immunol (2006) 1.56
Identification of the heparan sulfate binding sites in the cellular prion protein. J Biol Chem (2002) 1.41
A systems biology approach for the investigation of the heparin/heparan sulfate interactome. J Biol Chem (2011) 1.39
A molecular mechanism for the heparan sulfate dependence of slit-robo signaling. J Biol Chem (2006) 1.37
Rational and combinatorial design of peptide capping ligands for gold nanoparticles. J Am Chem Soc (2004) 1.34
Lactadherin binds selectively to membranes containing phosphatidyl-L-serine and increased curvature. Biochim Biophys Acta (2004) 1.33
A highly sensitive and dynamic immunofluorescent cytometric bead assay for the detection of HIV-1 p24. J Virol Methods (2009) 1.31
Interaction with glycosaminoglycans is required for cyclophilin B to trigger integrin-mediated adhesion of peripheral blood T lymphocytes to extracellular matrix. Proc Natl Acad Sci U S A (2002) 1.30
Semen of HIV-1-infected individuals: local shedding of herpesviruses and reprogrammed cytokine network. J Infect Dis (2011) 1.29
N-glycosylation of fibroblast growth factor receptor 1 regulates ligand and heparan sulfate co-receptor binding. J Biol Chem (2006) 1.27
Fabrication of carbohydrate microarrays on gold surfaces: direct attachment of nonderivatized oligosaccharides to hydrazide-modified self-assembled monolayers. Anal Chem (2006) 1.24
Differential effects of heparin saccharides on the formation of specific fibroblast growth factor (FGF) and FGF receptor complexes. J Biol Chem (2001) 1.22
Syndecan-1/CD147 association is essential for cyclophilin B-induced activation of p44/42 mitogen-activated protein kinases and promotion of cell adhesion and chemotaxis. Glycobiology (2007) 1.21
HIV-1 induced activation of CD4+ T cells creates new targets for HIV-1 infection in human lymphoid tissue ex vivo. Blood (2007) 1.19
Lactadherin detects early phosphatidylserine exposure on immortalized leukemia cells undergoing programmed cell death. Cytometry A (2006) 1.19
Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling. Glycobiology (2002) 1.18
Endocan expression and localization in human glioblastomas. J Neuropathol Exp Neurol (2009) 1.16
Fibroblast growth factors share binding sites in heparan sulphate. Biochem J (2005) 1.15
Specific heparan sulfate structures modulate FGF10-mediated submandibular gland epithelial morphogenesis and differentiation. J Biol Chem (2008) 1.14
Dermatan sulfate binds and potentiates activity of keratinocyte growth factor (FGF-7). J Biol Chem (2002) 1.11
Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's beta-secretase. J Cell Biol (2003) 1.11
Extracellular regulation of developmental cell signaling by XtSulf1. Dev Biol (2008) 1.10
Specific heparan sulfate structures involved in retinal axon targeting. Development (2002) 1.09
Heparan 2-O-sulfotransferase, hst-2, is essential for normal cell migration in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2005) 1.09
A versatile gold surface approach for fabrication and interrogation of glycoarrays. Chembiochem (2008) 1.08
Interactions of hepatocyte growth factor/scatter factor with various glycosaminoglycans reveal an important interplay between the presence of iduronate and sulfate density. J Biol Chem (2007) 1.08
Fibroblast growth factor receptors 1 and 2 interact differently with heparin/heparan sulfate. Implications for dynamic assembly of a ternary signaling complex. J Biol Chem (2002) 1.07
Rapid purification and high sensitivity analysis of heparan sulfate from cells and tissues: toward glycomics profiling. J Biol Chem (2009) 1.06
Long-term tracking of cells using inorganic nanoparticles as contrast agents: are we there yet? Chem Soc Rev (2012) 1.06
Vascular endocan (ESM-1) is markedly overexpressed in clear cell renal cell carcinoma. Histopathology (2010) 1.05
Cathepsin L digestion of nanobioconjugates upon endocytosis. ACS Nano (2009) 1.05
Interleukin-7 facilitates HIV-1 transmission to cervico-vaginal tissue ex vivo. PLoS Pathog (2013) 1.05
Heparan sulfate phage display antibodies identify distinct epitopes with complex binding characteristics: insights into protein binding specificities. J Biol Chem (2009) 1.05
Viral interactions in human lymphoid tissue: Human herpesvirus 7 suppresses the replication of CCR5-tropic human immunodeficiency virus type 1 via CD4 modulation. J Virol (2006) 1.04
The heparan sulfate motif (GlcNS6S-IdoA2S)3, common in heparin, has a strict topography and is involved in cell behavior and disease. J Biol Chem (2010) 1.03
The basic C-terminal amino acids of calcium-binding protein S100A4 promote metastasis. Carcinogenesis (2008) 1.02
Synthesis of a targeted library of heparan sulfate hexa- to dodecasaccharides as inhibitors of β-secretase: potential therapeutics for Alzheimer's disease. Chemistry (2013) 1.02
The heparin/heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue. J Biol Chem (2007) 1.02
Novel mechanisms of fibroblast growth factor receptor 1 regulation by extracellular matrix protein anosmin-1. J Biol Chem (2009) 1.01
Sonic hedgehog induces epidermal growth factor dependent matrix infiltration in HaCaT keratinocytes. J Invest Dermatol (2005) 1.01
War and peace between microbes: HIV-1 interactions with coinfecting viruses. Cell Host Microbe (2009) 1.00
Cervico-vaginal tissue ex vivo as a model to study early events in HIV-1 infection. Am J Reprod Immunol (2011) 1.00
A generic approach to monofunctionalized protein-like gold nanoparticles based on immobilized metal ion affinity chromatography. Chembiochem (2006) 0.98
Mechanisms associated with HIV-1 resistance to acyclovir by the V75I mutation in reverse transcriptase. J Biol Chem (2009) 0.98
Cobalt nanoparticles as a novel magnetic resonance contrast agent--relaxivities at 1.5 and 3 Tesla. Contrast Media Mol Imaging (2008) 0.97
Self-association of calcium-binding protein S100A4 and metastasis. J Biol Chem (2009) 0.97
Contrasting roles for TLR ligands in HIV-1 pathogenesis. PLoS One (2010) 0.97
Extracellular interactome of the FGF receptor-ligand system: complexities and the relative simplicity of the worm. Dev Dyn (2009) 0.96
Mutually antagonistic actions of S100A4 and S100A1 on normal and metastatic phenotypes. Oncogene (2005) 0.95
Software tool for the structural determination of glycosaminoglycans by mass spectrometry. Anal Chem (2008) 0.95
Generating heparan sulfate saccharide libraries for glycomics applications. Nat Protoc (2010) 0.95
ESM-1 expression in stromal cells is predictive of recurrence after radiofrequency ablation in early hepatocellular carcinoma. J Hepatol (2013) 0.95
The crystal structure at 2A resolution of the Ca2+ -binding protein S100P. J Mol Biol (2003) 0.95
Sef is an inhibitor of proinflammatory cytokine signaling, acting by cytoplasmic sequestration of NF-κB. Dev Cell (2012) 0.95
Kinase-catalyzed modification of gold nanoparticles: a new approach to colorimetric kinase activity screening. J Am Chem Soc (2006) 0.94
Differential scanning fluorimetry measurement of protein stability changes upon binding to glycosaminoglycans: a screening test for binding specificity. Anal Chem (2010) 0.94
Alternative splicing generates an isoform of the human Sef gene with altered subcellular localization and specificity. Proc Natl Acad Sci U S A (2004) 0.94
Disaccharide compositional analysis of heparan sulfate and heparin polysaccharides using UV or high-sensitivity fluorescence (BODIPY) detection. Nat Protoc (2010) 0.94
Cell surface expression of CD147/EMMPRIN is regulated by cyclophilin 60. J Biol Chem (2005) 0.93
Labelling heparan sulphate saccharides with chromophore, fluorescence and mass tags for HPLC and MS separations. Methods Mol Biol (2009) 0.93
Aquaglyceroporins, one channel for two molecules. Biochim Biophys Acta (2002) 0.93
Serum proteoglycans as prognostic biomarkers of hepatocellular carcinoma in patients with alcoholic cirrhosis. Cancer Epidemiol Biomarkers Prev (2013) 0.93
N-Glycosylation regulates fibroblast growth factor receptor/EGL-15 activity in Caenorhabditis elegans in vivo. J Biol Chem (2009) 0.92
Endothelial expression of endocan is strongly associated with tumor progression in pituitary adenoma. Brain Pathol (2012) 0.92
Identification of heparin-binding sites in proteins by selective labeling. Mol Cell Proteomics (2009) 0.92
Robust ligand shells for biological applications of gold nanoparticles. Langmuir (2008) 0.92
Structural and functional characterization of the interaction between cyclophilin B and a heparin-derived oligosaccharide. J Biol Chem (2007) 0.92
Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships. Org Biomol Chem (2010) 0.92
Targeting perlecan in human keratinocytes reveals novel roles for perlecan in epidermal formation. J Biol Chem (2005) 0.92
Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificity. J Biol Chem (2012) 0.92
Expression of human FE65 in amyloid precursor protein transgenic mice is associated with a reduction in beta-amyloid load. J Neurochem (2005) 0.91
The application of phosphoramidate protide technology to acyclovir confers anti-HIV inhibition. J Med Chem (2009) 0.91
Influence of substitution pattern and cation binding on conformation and activity in heparin derivatives. Glycobiology (2007) 0.91
The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor. Cell Commun Signal (2010) 0.91