Jack L Arbiser

Author PubWeight™ 97.00‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity. Nat Med 2011 3.09
2 Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo. J Biol Chem 2003 2.44
3 Overexpression of Akt converts radial growth melanoma to vertical growth melanoma. J Clin Invest 2007 2.22
4 Mitogen-actived protein kinase activation is an early event in melanoma progression. Clin Cancer Res 2002 2.18
5 Targeted therapy of oral hairy leukoplakia with gentian violet. J Am Acad Dermatol 2008 2.17
6 A key role for NOX4 in epithelial cell death during development of lung fibrosis. Antioxid Redox Signal 2011 1.79
7 Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice. J Invest Dermatol 2006 1.72
8 Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice. J Clin Invest 2009 1.68
9 Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis. Breast Cancer Res 2012 1.65
10 Honokiol, a multifunctional antiangiogenic and antitumor agent. Antioxid Redox Signal 2009 1.53
11 Keloids demonstrate high-level epidermal expression of vascular endothelial growth factor. J Am Acad Dermatol 2004 1.52
12 Honokiol suppresses survival signals mediated by Ras-dependent phospholipase D activity in human cancer cells. Clin Cancer Res 2008 1.43
13 Malignant transformation of melanocytes to melanoma by constitutive activation of mitogen-activated protein kinase kinase (MAPKK) signaling. J Biol Chem 2003 1.39
14 A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells. Proc Natl Acad Sci U S A 2008 1.33
15 Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway. Mol Cancer Res 2006 1.32
16 The reactive oxygen-driven tumor: relevance to melanoma. Pigment Cell Melanoma Res 2008 1.31
17 Reactive oxygen-induced carcinogenesis causes hypermethylation of p16(Ink4a) and activation of MAP kinase. Mol Med 2002 1.25
18 Honokiol inhibits epidermal growth factor receptor signaling and enhances the antitumor effects of epidermal growth factor receptor inhibitors. Clin Cancer Res 2010 1.25
19 Reactive oxygen signaling and MAPK activation distinguish Epstein-Barr Virus (EBV)-positive versus EBV-negative Burkitt's lymphoma. Proc Natl Acad Sci U S A 2004 1.22
20 Honokiol, a natural plant product, inhibits the bone metastatic growth of human prostate cancer cells. Cancer 2007 1.19
21 Honokiol is a potent scavenger of superoxide and peroxyl radicals. Biochem Pharmacol 2008 1.17
22 Honokiol, a natural plant product, inhibits inflammatory signals and alleviates inflammatory arthritis. J Immunol 2007 1.16
23 Gentian violet: a 19th century drug re-emerges in the 21st century. Exp Dermatol 2013 1.13
24 AKT1 overexpression in endothelial cells leads to the development of cutaneous vascular malformations in vivo. Arch Dermatol 2007 1.12
25 Mammalian target of rapamycin (mTOR) is activated in cutaneous vascular malformations in vivo. Lymphat Res Biol 2007 1.12
26 Secreted frizzle-related protein 2 stimulates angiogenesis via a calcineurin/NFAT signaling pathway. Cancer Res 2009 1.12
27 Anti-invasive adjuvant therapy with imipramine blue enhances chemotherapeutic efficacy against glioma. Sci Transl Med 2012 1.12
28 Transgenic expression of dominant negative tuberin through a strong constitutive promoter results in a tissue-specific tuberous sclerosis phenotype in the skin and brain. J Biol Chem 2004 1.04
29 Tris (dibenzylideneacetone) dipalladium, a N-myristoyltransferase-1 inhibitor, is effective against melanoma growth in vitro and in vivo. Clin Cancer Res 2008 1.03
30 Efficacy of topical application of eosin for ulcerated hemangiomas. J Am Acad Dermatol 2009 1.03
31 Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complex. Neurobiol Dis 2011 1.03
32 Effectiveness of gentian violet and similar products commonly used to treat pyodermas. Dermatol Clin 2011 1.01
33 Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization. Cancer Res 2009 1.01
34 Expression of the neural stem cell markers NG2 and L1 in human angiomyolipoma: are angiomyolipomas neoplasms of stem cells? Mol Med 2007 1.01
35 Angiomotin expression promotes hemangioendothelioma invasion. Oncogene 2004 0.99
36 Combination therapy of imiquimod and gentian violet for cutaneous melanoma metastases. J Am Acad Dermatol 2012 0.98
37 Disruption of the mitochondrial thioredoxin system as a cell death mechanism of cationic triphenylmethanes. Free Radic Biol Med 2011 0.98
38 Expression of Wilms tumor 1 gene distinguishes vascular malformations from proliferative endothelial lesions. Arch Dermatol 2005 0.97
39 Synthesis and biological evaluation of aromatic enones related to curcumin. Bioorg Med Chem 2005 0.97
40 Infectious angiogenesis: Bartonella bacilliformis infection results in endothelial production of angiopoetin-2 and epidermal production of vascular endothelial growth factor. Am J Pathol 2003 0.96
41 Honokiol, a natural biphenyl, inhibits in vitro and in vivo growth of breast cancer through induction of apoptosis and cell cycle arrest. Int J Oncol 2007 0.96
42 Targeting NADPH oxidases for the treatment of cancer and inflammation. Cell Mol Life Sci 2012 0.96
43 Rapamycin (sirolimus) as a steroid-sparing agent in dermatomyositis. J Am Acad Dermatol 2005 0.96
44 Curcumin as an inhibitor of angiogenesis. Adv Exp Med Biol 2007 0.95
45 The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis. Mol Cancer Ther 2008 0.94
46 Weight loss-induced calciphylaxis: potential role of matrix metalloproteinases. J Dermatol 2003 0.94
47 The role of angiogenesis in the pathogenesis of psoriasis. Autoimmunity 2009 0.93
48 Molecular pathogenesis of vascular anomalies: classification into three categories based upon clinical and biochemical characteristics. Lymphat Res Biol 2003 0.92
49 Angiogenesis in cutaneous lesions of leprosy: implications for treatment. Arch Dermatol 2007 0.91
50 Tuberous sclerosis-associated neoplasms express activated p42/44 mitogen-activated protein (MAP) kinase, and inhibition of MAP kinase signaling results in decreased in vivo tumor growth. Clin Cancer Res 2003 0.91
51 Facile purification of honokiol and its antiviral and cytotoxic properties. J Med Chem 2006 0.90
52 Immunosuppression may be present within condyloma acuminata. J Am Acad Dermatol 2008 0.90
53 gli-1 Oncogene is highly expressed in granulomatous skin disorders, including sarcoidosis, granuloma annulare, and necrobiosis lipoidica diabeticorum. Arch Dermatol 2005 0.90
54 Malignant transformation of human cells by constitutive expression of platelet-derived growth factor-BB. J Biol Chem 2005 0.90
55 Design, synthesis, and biological evaluation of angiogenesis inhibitors: aromatic enone and dienone analogues of curcumin. Bioorg Med Chem Lett 2003 0.89
56 Reductions in funding for medical research. JAMA 2013 0.89
57 Enhanced MCP-1 release by keloid CD14+ cells augments fibroblast proliferation: role of MCP-1 and Akt pathway in keloids. Exp Dermatol 2010 0.88
58 The natural product honokiol inhibits calcineurin inhibitor-induced and Ras-mediated tumor promoting pathways. Cancer Lett 2013 0.88
59 Inactivation of NADPH oxidases NOX4 and NOX5 protects human primary fibroblasts from ionizing radiation-induced DNA damage. Radiat Res 2015 0.88
60 Fumagillin: an anti-infective as a parent molecule for novel angiogenesis inhibitors. Expert Rev Anti Infect Ther 2007 0.88
61 Synthesis, cytotoxicity, and antiviral activities of new neolignans related to honokiol and magnolol. Bioorg Med Chem Lett 2007 0.86
62 Solenopsin A, a venom alkaloid from the fire ant Solenopsis invicta, inhibits quorum-sensing signaling in Pseudomonas aeruginosa. J Infect Dis 2008 0.86
63 PSK and Trx80 inhibit B-cell growth in EBV-infected cord blood mononuclear cells through T cells activated by the monocyte products IL-15 and IL-12. Blood 2004 0.86
64 Targeting the intrinsic inflammatory pathway: honokiol exerts proapoptotic effects through STAT3 inhibition in transformed Barrett's cells. Am J Physiol Gastrointest Liver Physiol 2012 0.85
65 The antidepressant sertraline downregulates Akt and has activity against melanoma cells. Pigment Cell Melanoma Res 2008 0.85
66 Maspin expression, angiogenesis, prognostic parameters, and outcome in malignant melanoma. J Am Acad Dermatol 2009 0.85
67 Efficacy of rapamycin in scleroderma: a case study. Lymphat Res Biol 2008 0.84
68 Tumor necrosis factor-related apoptosis-inducing ligand can induce apoptosis in subsets of premalignant cells. Am J Pathol 2004 0.84
69 Phosphorylation by mitogen-activated protein kinase mediates the hypoxia-induced turnover of the TAL1/SCL transcription factor in endothelial cells. J Biol Chem 2002 0.82
70 Cutaneous lesions of secondary syphilis are highly angiogenic. J Am Acad Dermatol 2003 0.82
71 The duality of angiogenesis: implications for therapy of human disease. J Invest Dermatol 2006 0.81
72 A nonsteroidal alternative to impetiginized eczema in the emergency room. J Am Acad Dermatol 2010 0.81
73 Honokiol stimulates osteoblastogenesis by suppressing NF-κB activation. Int J Mol Med 2011 0.81
74 Rapid improvement of nephrogenic systemic fibrosis with rapamycin therapy: possible role of phospho-70-ribosomal-S6 kinase. J Am Acad Dermatol 2010 0.81
75 Combination therapy of doxycycline and topical tacrolimus for venous ulcers. Arch Dermatol 2005 0.81
76 Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo. J Invest Dermatol 2007 0.81
77 Regulation of endothelial cell differentiation and transformation by H-Ras. Exp Cell Res 2003 0.80
78 Wilms tumor 1 expression present in most melanomas but nearly absent in nevi. Arch Dermatol 2006 0.80
79 Cooperative benefit for the combination of rapamycin and imatinib in tuberous sclerosis complex neoplasia. Vasc Cell 2012 0.80
80 Honokiol induces cell cycle arrest and apoptosis via inhibition of survival signals in adult T-cell leukemia. Biochim Biophys Acta 2012 0.80
81 Gentian violet is safe. J Am Acad Dermatol 2009 0.80
82 Honokiol inhibits androgen receptor activity in prostate cancer cells. Prostate 2013 0.80
83 The antioxidant paradox: what are antioxidants and how should they be used in a therapeutic context for cancer. Future Med Chem 2014 0.79
84 Application of angiogenesis to clinical dermatology. Adv Dermatol 2008 0.79
85 High level expression of angiopoietin-2 in human abscesses. J Am Acad Dermatol 2011 0.78
86 Novel antiangiogenic agents in dermatology. Arch Biochem Biophys 2010 0.78
87 Apolipoprotein D is down-regulated during malignant transformation of neurofibromas. Hum Pathol 2005 0.77
88 In vivo Gram staining of tinea versicolor. JAMA Dermatol 2013 0.76
89 Melanomas reveal their nakedness: uncovered by interferon alfa. Arch Dermatol 2009 0.75
90 Role of manganese superoxide dismutase in cancer. Nat Med 2003 0.75
91 Disseminated pyoderma gangrenosum: role for vascular endothelial growth factor and hypoxia inducible factor-2. J Am Acad Dermatol 2009 0.75
92 Ulcerative granulomatous mycosis fungoides. Skinmed 2010 0.75
93 Honokiol Increases CD4+ T Cell Activation and Decreases TNF but Fails to Improve Survival Following Sepsis. Shock 2017 0.75
94 Effective local anesthesia for onabotulinumtoxin A injections to treat hyperhidrosis associated with traumatic amputation. Dermatol Online J 2016 0.75