Werner Reutter

Author PubWeight™ 62.55‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Sialylation is essential for early development in mice. Proc Natl Acad Sci U S A 2002 2.15
2 Versatile biosynthetic engineering of sialic acid in living cells using synthetic sialic acid analogues. J Biol Chem 2001 1.22
3 Two-color glycan labeling of live cells by a combination of Diels-Alder and click chemistry. Angew Chem Int Ed Engl 2013 1.18
4 The homozygous M712T mutation of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase results in reduced enzyme activities but not in altered overall cellular sialylation in hereditary inclusion body myopathy. FEBS Lett 2004 1.17
5 No overall hyposialylation in hereditary inclusion body myopathy myoblasts carrying the homozygous M712T GNE mutation. Biochem Biophys Res Commun 2005 1.16
6 CEACAM1 (CD66a) mediates delay of spontaneous and Fas ligand-induced apoptosis in granulocytes. Eur J Immunol 2005 1.13
7 Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface. J Biol Chem 2004 1.11
8 Enhanced sialylation of EPO by overexpression of UDP-GlcNAc 2-epimerase/ManAc kinase containing a sialuria mutation in CHO cells. FEBS Lett 2007 1.03
9 Engineering the sialic acid in organs of mice using N-propanoylmannosamine. Biochim Biophys Acta 2006 1.02
10 Deficiency of CD26 results in a change of cytokine and immunoglobulin secretion after stimulation by pokeweed mitogen. Eur J Immunol 2003 0.99
11 Sialic acid metabolism is involved in the regulation of gene expression during neuronal differentiation of PC12 cells. Glycoconj J 2008 0.98
12 The cell adhesion receptor carcinoembryonic antigen-related cell adhesion molecule 1 regulates nucleocytoplasmic trafficking of DNA polymerase delta-interacting protein 38. J Biol Chem 2007 0.96
13 Biochemical engineering of cell surface sialic acids stimulates axonal growth. J Neurosci 2002 0.96
14 Evidence for dynamic interplay of different oligomeric states of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase by biophysical methods. J Mol Biol 2007 0.93
15 Structure and function of N-acetylglucosamine kinase. Identification of two active site cysteines. Eur J Biochem 2002 0.93
16 The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1. Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter. FEBS J 2005 0.91
17 Regulation and pathophysiological implications of UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) as the key enzyme of sialic acid biosynthesis. Biol Chem 2009 0.91
18 Comparative proteomics of rat liver and Morris hepatoma 7777 plasma membranes. J Chromatogr B Analyt Technol Biomed Life Sci 2006 0.90
19 N-Propionylmannosamine-induced over-expression and secretion of thioredoxin leads to neurite outgrowth of PC12 cells. Biochem Biophys Res Commun 2010 0.90
20 Quantification of nucleotide-activated sialic acids by a combination of reduction and fluorescent labeling. Anal Chem 2010 0.90
21 The neural cell adhesion molecule is associated with major components of the cytoskeleton. Biochem Biophys Res Commun 2003 0.90
22 Cytoplasmic domain of NCAM 180 reduces NCAM-mediated neurite outgrowth. J Neurosci Res 2004 0.89
23 Selective inhibition of polysialyltransferase ST8SiaII by unnatural sialic acids. Exp Cell Res 2004 0.89
24 2',3'-Dialdehydo-UDP-N-acetylglucosamine inhibits UDP-N-acetylglucosamine 2-epimerase, the key enzyme of sialic acid biosynthesis. FEBS Lett 2002 0.87
25 Epigenetically mediated loss of UDP-GlcNAc 2-epimerase/ManNAc kinase expression in hyposialylated cell lines. Biochem Biophys Res Commun 2003 0.86
26 The intracellular concentration of sialic acid regulates the polysialylation of the neural cell adhesion molecule. FEBS Lett 2005 0.86
27 Biochemical engineering of the acyl side chain of sialic acids stimulates integrin-dependent adhesion of HL60 cells to fibronectin. J Mol Med (Berl) 2002 0.86
28 Synthesis and biochemical properties of reversible inhibitors of UDP-N-acetylglucosamine 2-epimerase. Angew Chem Int Ed Engl 2004 0.85
29 Increased expression of the selectin ligand sialyl-Lewis(x) by biochemical engineering of sialic acids. Exp Cell Res 2004 0.85
30 Crystal structures of HIV-1 Tat-derived nonapeptides Tat-(1-9) and Trp2-Tat-(1-9) bound to the active site of dipeptidyl-peptidase IV (CD26). J Biol Chem 2005 0.85
31 GLIS, a bioactive proteoglycan fraction from Ganoderma lucidum, displays anti-tumour activity by increasing both humoral and cellular immune response. Life Sci 2010 0.85
32 Biochemical engineering of the N-acyl side chain of sialic acids alters the kinetics of a glycosylated potassium channel Kv3.1. FEBS Lett 2011 0.85
33 In vivo stimulation of early peripheral axon regeneration by N-propionylmannosamine in the presence of polysialyltransferase ST8SIA2. J Neural Transm (Vienna) 2015 0.84
34 Phospholipase Cgamma binds alpha1beta1 integrin and modulates alpha1beta1 integrin-specific adhesion. J Biol Chem 2001 0.84
35 Sialic acid biosynthesis: stereochemistry and mechanism of the reaction catalyzed by the mammalian UDP-N-acetylglucosamine 2-epimerase. J Am Chem Soc 2003 0.83
36 Synthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the mitochondrial death pathway. Apoptosis 2011 0.83
37 Activation of B lymphocytes by GLIS, a bioactive proteoglycan from Ganoderma lucidum. Life Sci 2002 0.83
38 Crystal structures of N-acetylmannosamine kinase provide insights into enzyme activity and inhibition. J Biol Chem 2012 0.83
39 PDGF-BB enhances alpha1beta1 integrin-mediated activation of the ERK/AP-1 pathway involved in collagen matrix remodeling by rat mesangial cells. J Cell Physiol 2004 0.83
40 Novel UDP-glycal derivatives as transition state analogue inhibitors of UDP-GlcNAc 2-epimerase. J Org Chem 2004 0.82
41 Homeostatic regulation of NCAM polysialylation is critical for correct synaptic targeting. Cell Mol Life Sci 2011 0.82
42 The key enzyme of sialic acid biosynthesis (GNE) promotes neurite outgrowth of PC12 cells. Neuroreport 2008 0.82
43 Glycosidated phospholipids: uncoupling of signalling pathways at the plasma membrane. Br J Pharmacol 2010 0.81
44 Purification and characterization of N-acetylneuraminic acid-9-phosphate synthase from rat liver. Glycobiology 2002 0.81
45 Experimental approaches to interfere with the polysialylation of the neural cell adhesion molecule in vitro and in vivo. J Neurochem 2007 0.81
46 Biochemical engineering of the N-acyl side chain of sialic acid leads to increased calcium influx from intracellular compartments and promotes differentiation of HL60 cells. FEBS Lett 2004 0.81
47 The 3D structure of rat DPPIV/CD26 as obtained by cryo-TEM and single particle analysis. Biochem Biophys Res Commun 2003 0.81
48 Domain-specific characteristics of the bifunctional key enzyme of sialic acid biosynthesis, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase. Biochem J 2004 0.80
49 The cytoplasmic tail of the alpha3 integrin subunit promotes neurite outgrowth in PC12 cells. J Neurosci Res 2005 0.80
50 Expression, purification, and characterization of human dipeptidyl peptidase IV/CD26 in Sf9 insect cells. Protein Expr Purif 2002 0.80
51 Occurrence of the human tumor-specific antigen structure Galβ1-3GalNAcα- (Thomsen-Friedenreich) and related structures on gut bacteria: prevalence, immunochemical analysis and structural confirmation. Glycobiology 2011 0.80
52 3D structure of the CD26-ADA complex obtained by cryo-EM and single particle analysis. Biochem Biophys Res Commun 2004 0.80
53 Novel cytosolic binding partners of the neural cell adhesion molecule: mapping the binding domains of PLC gamma, LANP, TOAD-64, syndapin, PP1, and PP2A. Biochemistry 2005 0.80
54 Clustering-induced signaling of CEACAM1 in PC12 cells. Biol Chem 2002 0.80
55 Characterization of ligand binding to the bifunctional key enzyme in the sialic acid biosynthesis by NMR: I. Investigation of the UDP-GlcNAc 2-epimerase functionality. J Biol Chem 2004 0.79
56 Molecular mechanism and structural basis of interactions of dipeptidyl peptidase IV with adenosine deaminase and human immunodeficiency virus type-1 transcription transactivator. Eur J Cell Biol 2011 0.79
57 Mass spectrometry-based analysis of rat liver and hepatocellular carcinoma Morris hepatoma 7777 plasma membrane proteome. Anal Chem 2013 0.79
58 Glucosamine-glycerophospholipids that activate cell-matrix adhesion and migration. J Med Chem 2005 0.79
59 Effects of anti-alpha1 integrin subunit antibody on anti-Thy-1 glomerulonephritis. Lab Invest 2002 0.78
60 Dipeptidyl peptidase IV/CD26 in T cell activation, cytokine secretion and immunoglobulin production. Adv Exp Med Biol 2003 0.78
61 Invasion of Trypanosoma cruzi into host cells is impaired by N-propionylmannosamine and other N-acylmannosamines. Glycoconj J 2011 0.78
62 The ether lipid inositol-C2-PAF is a potent inhibitor of cell proliferation in HaCaT cells. Chembiochem 2006 0.78
63 Involvement of sialic acid in the regulation of γ--aminobutyric acid uptake activity of γ-aminobutyric acid transporter 1. Glycobiology 2010 0.77
64 Identification of members of the annexin family in the detergent-insoluble fraction of rat Morris hepatoma plasma membranes. J Chromatogr A 2006 0.77
65 UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, functionally expressed in and purified from Escherichia coli, yeast, and insect cells. Protein Expr Purif 2004 0.77
66 [Human lectins and their correspondent glycans in cell biology and clinical medicine]. Med Klin (Munich) 2003 0.76
67 Characterization of ligand binding to the bifunctional key enzyme in the sialic acid biosynthesis by NMR: II. Investigation of the ManNAc kinase functionality. J Biol Chem 2004 0.76
68 Metabolic glycoengineering of mesenchymal stromal cells with N-propanoylmannosamine. Glycobiology 2013 0.76
69 Metabolism of galactose in the brain and liver of rats and its conversion into glutamate and other amino acids. J Neural Transm (Vienna) 2008 0.76
70 Liver-specific increase of UTP and UDP-sugar concentrations in rats induced by dietary vitamin B6-deficiency and its relation to complex N-glycan structures of liver membrane-proteins. Glycoconj J 2007 0.75
71 Interaction of human dipeptidyl peptidase IV and human immunodeficiency virus type-1 transcription transactivator in Sf9 cells. Virol J 2010 0.75
72 The novel synthetic ether lipid inositol-C2-PAF inhibits phosphorylation of the tyrosine kinases Src and FAK independent of integrin activation in transformed skin cells. Biochem Pharmacol 2011 0.75
73 N-propanoylmannosamine interferes with O-GlcNAc modification of the tyrosine 3-monooxygenase and stimulates dopamine secretion. J Neurosci Res 2008 0.75
74 Secreted CEACAM1 splice variants in rat cell lines and in vivo in rat serum. Biochem Biophys Res Commun 2002 0.75
75 [Activation of mouse macrophages by the alkali-extracted polysaccharide from spore of Ganoderma lucidum]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2004 0.75
76 Stimulation of human peripheral blood mononuclear cells by the sialic acid precursor N-propanoylmannosamine. Glycoconj J 2013 0.75
77 Structure-function relationship of DPP IV: insights into its dimerisation and gelatinase activity. Adv Exp Med Biol 2003 0.75