Jung Young Lee

Author PubWeight™ 118.04‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene 2005 4.07
2 Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast carcinomas. Clin Cancer Res 2006 1.98
3 Increased expression of histone deacetylase 2 is found in human gastric cancer. APMIS 2005 1.77
4 Somatic mutations of EGFR gene in squamous cell carcinoma of the head and neck. Clin Cancer Res 2005 1.70
5 Inactivating mutations of caspase-8 gene in colorectal carcinomas. Gastroenterology 2003 1.56
6 Sirtuin7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125b. Hepatology 2013 1.49
7 Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling. Hepatology 2005 1.48
8 Somatic mutations of the ERBB4 kinase domain in human cancers. Int J Cancer 2006 1.38
9 Inactivating mutations of CASP10 gene in non-Hodgkin lymphomas. Blood 2002 1.30
10 BRAF and KRAS mutations in stomach cancer. Oncogene 2003 1.27
11 Genetic alterations of the KLF6 gene in gastric cancer. Oncogene 2005 1.26
12 Nod1, a CARD protein, enhances pro-interleukin-1beta processing through the interaction with pro-caspase-1. Biochem Biophys Res Commun 2002 1.23
13 ArrayCyGHt: a web application for analysis and visualization of array-CGH data. Bioinformatics 2005 1.23
14 Altered expression of the KLF4 in colorectal cancers. Pathol Res Pract 2006 1.23
15 CASPASE-8 gene is inactivated by somatic mutations in gastric carcinomas. Cancer Res 2005 1.20
16 Mutational analysis of EGFR and K-RAS genes in lung adenocarcinomas. Virchows Arch 2005 1.20
17 ERBB2 kinase domain mutation in the lung squamous cell carcinoma. Cancer Lett 2005 1.19
18 MiR-145 functions as a tumor suppressor by directly targeting histone deacetylase 2 in liver cancer. Cancer Lett 2013 1.17
19 Decreased expression of tumour suppressor Bax-interacting factor-1 (Bif-1), a Bax activator, in gastric carcinomas. Pathology 2006 1.16
20 Aberrant regulation of HDAC2 mediates proliferation of hepatocellular carcinoma cells by deregulating expression of G1/S cell cycle proteins. PLoS One 2011 1.12
21 Mutations of beta-catenin and AXIN I genes are a late event in human hepatocellular carcinogenesis. Liver Int 2005 1.11
22 Immunohistochemical expression of integrins and extracellular matrix proteins in non-small cell lung cancer: correlation with lymph node metastasis. Lung Cancer 2003 1.11
23 Caspase-8 gene is frequently inactivated by the frameshift somatic mutation 1225_1226delTG in hepatocellular carcinomas. Oncogene 2005 1.09
24 Increased expression of FLIP, an inhibitor of Fas-mediated apoptosis, in stomach cancer. APMIS 2003 1.08
25 Targeted disruption of Nemo-like kinase inhibits tumor cell growth by simultaneous suppression of cyclin D1 and CDK2 in human hepatocellular carcinoma. J Cell Biochem 2010 1.07
26 Loss of caspase-2, -6 and -7 expression in gastric cancers. APMIS 2004 1.06
27 Overexpression of S100A4 is closely related to the aggressiveness of gastric cancer. APMIS 2003 1.05
28 Somatic mutations of CASP3 gene in human cancers. Hum Genet 2004 1.05
29 Inactivation of the Gastrokine 1 gene in gastric adenomas and carcinomas. J Pathol 2011 1.04
30 Comparing fluorescence in situ hybridization and chromogenic in situ hybridization methods to determine the HER2/neu status in primary breast carcinoma using tissue microarray. Mod Pathol 2003 1.04
31 Gastrokine 1 functions as a tumor suppressor by inhibition of epithelial-mesenchymal transition in gastric cancers. J Cancer Res Clin Oncol 2011 1.01
32 PDCD4 expression inversely correlated with miR-21 levels in gastric cancers. J Cancer Res Clin Oncol 2012 1.01
33 Mutational analysis of AKT1, AKT2 and AKT3 genes in common human carcinomas. Oncology 2006 1.00
34 Genetic alterations of the ATBF1 gene in gastric cancer. Clin Cancer Res 2007 0.99
35 GKN1-miR-185-DNMT1 axis suppresses gastric carcinogenesis through regulation of epigenetic alteration and cell cycle. Clin Cancer Res 2013 0.97
36 Genetic analysis of the liver putative tumor suppressor (LPTS) gene in hepatocellular carcinomas. Cancer Lett 2002 0.97
37 Inactivating mutations of CASPASE-7 gene in human cancers. Oncogene 2003 0.96
38 Non-small cell lung cancers frequently express phosphorylated Akt; an immunohistochemical study. APMIS 2002 0.95
39 Genetic and epigenetic alterations of the KLF6 gene in hepatocellular carcinoma. J Gastroenterol Hepatol 2006 0.95
40 HDAC2 overexpression confers oncogenic potential to human lung cancer cells by deregulating expression of apoptosis and cell cycle proteins. J Cell Biochem 2012 0.95
41 Hypermethylation of the RUNX3 gene in hepatocellular carcinoma. Exp Mol Med 2005 0.93
42 ERBB3 kinase domain mutations are rare in lung, breast and colon carcinomas. Int J Cancer 2006 0.92
43 Inactivating mutations of the Siah-1 gene in gastric cancer. Oncogene 2004 0.92
44 Alterations of Fas-pathway genes associated with nodal metastasis in non-small cell lung cancer. Oncogene 2002 0.92
45 Increased expression of Gab2, a scaffolding adaptor of the tyrosine kinase signalling, in gastric carcinomas. Pathology 2007 0.92
46 Inactivating mutations of the caspase-10 gene in gastric cancer. Oncogene 2002 0.92
47 HDAC1 inactivation induces mitotic defect and caspase-independent autophagic cell death in liver cancer. PLoS One 2012 0.91
48 DBC1 does not function as a negative regulator of SIRT1 in liver cancer. Oncol Lett 2012 0.91
49 Altered expression of KCNK9 in colorectal cancers. APMIS 2004 0.90
50 Somatic mutations of the beta-TrCP gene in gastric cancer. APMIS 2007 0.90
51 Expression of HGF/SF and Met protein is associated with genetic alterations of VHL gene in primary renal cell carcinomas. APMIS 2002 0.90
52 Overexpression of serine-threonine receptor kinase-associated protein in colorectal cancers. Pathol Int 2007 0.89
53 Histone deacetylase 6 functions as a tumor suppressor by activating c-Jun NH2-terminal kinase-mediated beclin 1-dependent autophagic cell death in liver cancer. Hepatology 2012 0.89
54 Inactivating mutation of the pro-apoptotic gene BID in gastric cancer. J Pathol 2004 0.88
55 Aspartic acid repeat polymorphism of the asporin gene with susceptibility to osteoarthritis of the knee in a Korean population. Knee 2008 0.88
56 TNF-α and TNF-β Polymorphisms are Associated with Susceptibility to Osteoarthritis in a Korean Population. Korean J Pathol 2012 0.87
57 Targeted disruption of S100P suppresses tumor cell growth by down-regulation of cyclin D1 and CDK2 in human hepatocellular carcinoma. Int J Oncol 2009 0.87
58 Inactivating mutations of proapoptotic Bad gene in human colon cancers. Carcinogenesis 2004 0.87
59 Gastrokine 1 regulates NF-κB signaling pathway and cytokine expression in gastric cancers. J Cell Biochem 2013 0.87
60 ERBB2 kinase domain mutation in a gastric cancer metastasis. APMIS 2005 0.86
61 Functional analysis of the NH2-terminal hydrophobic region and BRICHOS domain of GKN1. Biochem Biophys Res Commun 2013 0.86
62 HDAC2 provides a critical support to malignant progression of hepatocellular carcinoma through feedback control of mTORC1 and AKT. Cancer Res 2014 0.86
63 Absence of EGFR mutation in the kinase domain in common human cancers besides non-small cell lung cancer. Int J Cancer 2005 0.86
64 A single nucleotide polymorphism in the E-cadherin gene promoter-160 is not associated with risk of Korean gastric cancer. J Korean Med Sci 2003 0.86
65 Colorectal tumors frequently express phosphorylated mitogen-activated protein kinase. APMIS 2004 0.85
66 Genetic analysis of the DBC2 gene in gastric cancer. Acta Oncol 2007 0.85
67 Targeted inactivation of HDAC2 restores p16INK4a activity and exerts antitumor effects on human gastric cancer. Mol Cancer Res 2012 0.85
68 GKN2 contributes to the homeostasis of gastric mucosa by inhibiting GKN1 activity. J Cell Physiol 2014 0.85
69 Immunohistochemical analysis of Smac/DIABLO expression in human carcinomas and sarcomas. APMIS 2003 0.84
70 Activation-induced cytidine deaminase expression in gastric cancer. Tumour Biol 2008 0.84
71 Aberrant expression of SOX9 is associated with gastrokine 1 inactivation in gastric cancers. Gastric Cancer 2013 0.84
72 Decreased expression of annexin A10 in gastric cancer and its overexpression in tumor cell growth suppression. Oncol Rep 2010 0.84
73 Application of amplified RNA and evaluation of cRNA targets for spotted-oligonucleotide microarray. Biochem Biophys Res Commun 2004 0.84
74 Genetic and epigenetic analysis of the KLF4 gene in gastric cancer. APMIS 2007 0.84
75 Autotaxin (lysoPLD/NPP2) protects fibroblasts from apoptosis through its enzymatic product, lysophosphatidic acid, utilizing albumin-bound substrate. Biochem Biophys Res Commun 2005 0.83
76 Immunohistochemical and mutational analysis of apoptosis-inducing factor (AIF) in colorectal carcinomas. APMIS 2006 0.83
77 Programmed cell death 6 (PDCD6) as a prognostic marker for gastric cancers. Tumour Biol 2011 0.83
78 Mutational analysis of the CASP6 gene in colorectal and gastric carcinomas. APMIS 2006 0.83
79 Immunohistochemical analysis of apoptosis-inducing factor (AIF) expression in gastric carcinomas. Pathol Res Pract 2006 0.83
80 Mutational analysis of the ARAF gene in human cancers. APMIS 2005 0.82
81 Genetic alterations of the MYH gene in gastric cancer. Oncogene 2004 0.82
82 Association of IL-17A and IL-17F single nucleotide polymorphisms with susceptibility to osteoarthritis in a Korean population. Gene 2013 0.82
83 Discriminating the molecular basis of hepatotoxicity using the large-scale characteristic molecular signatures of toxicants by expression profiling analysis. Toxicology 2008 0.81
84 BH3 domain mutation of proapoptotic genes Bad, Bmf and Bcl-G is rare in transitional cell carcinomas of the urinary bladder. Pathology 2006 0.81
85 Genetic alterations of the KLF6 gene in colorectal cancers. APMIS 2006 0.81
86 Systemic cell-cycle suppression by Apicidin, a histone deacetylase inhibitor, in MDA-MB-435 cells. Int J Mol Med 2009 0.81
87 Mutational analysis of Noxa gene in human cancers. APMIS 2003 0.81
88 Identification of large-scale characteristic genes of Müllerian inhibiting substance in human ovarian cancer cells. Int J Mol Med 2009 0.80
89 Mutational analysis of PDPK1 kinase domain in gastric, colorectal and lung carcinomas. Acta Oncol 2006 0.80
90 Altered expression of CDX2 in colorectal cancers. APMIS 2006 0.80
91 Mutational analysis of PTPRT phosphatase domains in common human cancers. APMIS 2007 0.80
92 Mutational analysis of proapoptotic caspase-9 gene in common human carcinomas. APMIS 2006 0.80
93 Expression of nuclear and cytoplasmic phosphorylated FADD in gastric cancers. Pathol Res Pract 2007 0.80
94 Genetic alterations of the Cdx2 gene in gastric cancer. APMIS 2008 0.80
95 Absence of E17K mutation in the pleckstrin homology domain of AKT1 in gastrointestinal and liver cancers in the Korean population. APMIS 2008 0.80
96 Genetic alterations of the HCCS1 gene in Korean hepatocellular carcinoma. APMIS 2003 0.79
97 Kinase domain mutation of ERBB family genes is uncommon in acute leukemias. Leuk Res 2005 0.79
98 JAK2 V617F mutation is uncommon in non-Hodgkin lymphomas. Leuk Lymphoma 2006 0.79
99 Stomach cancer highly expresses both initiator and effector caspases; an immunohistochemical study. APMIS 2002 0.79
100 Lysyl oxidase G473A polymorphism is closely associated with susceptibility to gastric cancer in a South Korean population. APMIS 2011 0.79
101 Mitochondrial microsatellite instability of colorectal cancer stroma. Int J Cancer 2006 0.78
102 Mutational analysis of MYC in common epithelial cancers and acute leukemias. APMIS 2006 0.78
103 Mutational analysis of the kinase domain of MYLK2 gene in common human cancers. Pathol Res Pract 2006 0.78
104 Identification of characteristic molecular signature for volatile organic compounds in peripheral blood of rat. Toxicol Appl Pharmacol 2010 0.78
105 Genetic and epigenetic analysis of the EPHB2 gene in gastric cancers. APMIS 2007 0.78
106 Genetic and expression analysis of the KCNRG gene in hepatocellular carcinomas. Exp Mol Med 2006 0.78
107 Analysis of succinate dehydrogenase subunit B gene alterations in gastric cancers. Pathol Int 2010 0.78
108 Association of SOD1 and SOD2 single nucleotide polymorphisms with susceptibility to gastric cancer in a Korean population. APMIS 2012 0.78
109 Identification of large-scale molecular changes of Autotaxin(ENPP2) knock-down by small interfering RNA in breast cancer cells. Mol Cell Biochem 2006 0.78
110 Comparative analysis of expression profiling of early-stage carcinogenesis using nodule-in-nodule-type hepatocellular carcinoma. Eur J Gastroenterol Hepatol 2006 0.77
111 Characteristic molecular signature for the early detection and prediction of polycyclic aromatic hydrocarbons in rat liver. Toxicol Lett 2012 0.77
112 Absence of DKC1 exon 3 mutation in common human cancers. Acta Oncol 2006 0.77
113 Somatic mutation of pro-apoptosis caspase-6 gene is rare in breast and lung carcinomas. Pathology 2006 0.77
114 Genetic alterations and expression pattern of CEACAM1 in colorectal adenomas and cancers. Pathol Oncol Res 2010 0.77
115 Identification of post-generation effect of 3,4-methylenedioxymethamphetamine on the mouse brain by large-scale gene expression analysis. Toxicol Lett 2010 0.76
116 Transcriptomic configuration of mouse brain induced by adolescent exposure to 3,4-methylenedioxymethamphetamine. Toxicol Appl Pharmacol 2009 0.76
117 Genetic and epigenetic analysis of the VHL gene in gastric cancers. Acta Oncol 2008 0.76
118 Characteristic molecular signature for early detection and prediction of persistent organic pollutants in rat liver. Environ Sci Technol 2012 0.76
119 Molecular signature for early detection and prediction of polycyclic aromatic hydrocarbons in peripheral blood. Environ Sci Technol 2010 0.76
120 Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. J Appl Toxicol 2014 0.76
121 Transcriptional profiling and Wnt signaling activation in proliferation of human hepatic stellate cells induced by PDGF-BB. Korean J Hepatol 2009 0.76
122 Absence of JAK2 V617F mutation in gastric cancers. Acta Oncol 2006 0.76
123 Immunohistochemical analysis of Omi/HtrA2 expression in stomach cancer. APMIS 2003 0.75
124 Mutational analysis of P-loop domains of proapoptotic Nod1 and ARTS genes in colon carcinomas. Acta Oncol 2006 0.75
125 Absence of the ERBB2 kinase domain mutation in lung adenocarcinomas in Korean patients. Int J Cancer 2005 0.75
126 Pin1 gene mutation is a rare event in gastric cancer. APMIS 2006 0.75
127 Mutational analysis of the HIPK2 gene in keratoacanthoma and squamous cell carcinoma of the skin. APMIS 2011 0.75
128 Kinase domain mutation of MAP2K4 is rare in gastric, colorectal and lung carcinomas. Pathology 2006 0.75
129 Down-regulation of transforming growth factor beta receptor type III in hepatocellular carcinoma is not directly associated with genetic alterations or loss of heterozygosity. Oncol Rep 2009 0.75
130 Kinase domain mutation of NTRK3 gene is uncommon in gastric carcinomas. Acta Oncol 2005 0.75
131 SMAC/DIABLO mutation is uncommon in gastric and colorectal carcinomas. Pathology 2006 0.75
132 Mutation of FADD gene is rare in human colon and stomach cancers. APMIS 2004 0.75
133 Characteristic molecular signatures of early exposure to volatile organic compounds in rat liver. Biomarkers 2013 0.75
134 Absence of BH3 domain mutations in the proapoptotic Bcl-2 gene family in non-Hodgkin lymphomas. Acta Haematol 2006 0.75
135 Mutational analysis of Fas ligand gene in human non-Hodgkin lymphoma. APMIS 2003 0.75
136 Mutational analysis of salvador gene in human carcinomas. APMIS 2003 0.75
137 Absence of the mutation of serine/threonine kinase genes AKT2 and MYLK2 in acute leukemias. Eur J Haematol 2006 0.75