Published in Hepatology on February 11, 2013
The emerging and diverse roles of sirtuins in cancer: a clinical perspective. Onco Targets Ther (2013) 1.57
Sorting out functions of sirtuins in cancer. Oncogene (2013) 1.47
microRNA-148a dysregulation discriminates poor prognosis of hepatocellular carcinoma in association with USP4 overexpression. Oncotarget (2014) 1.22
MicroRNAs in hepatocellular carcinoma: regulation, function, and clinical implications. ScientificWorldJournal (2013) 1.16
The nucleolus—guardian of cellular homeostasis and genome integrity. Chromosoma (2013) 1.14
Sirtuin 7 plays a role in ribosome biogenesis and protein synthesis. Mol Cell Proteomics (2013) 1.08
miR-29b, miR-205 and miR-221 enhance chemosensitivity to gemcitabine in HuH28 human cholangiocarcinoma cells. PLoS One (2013) 1.00
DNA methylation, microRNAs, and their crosstalk as potential biomarkers in hepatocellular carcinoma. World J Gastroenterol (2014) 0.99
Cardio-miRNAs and onco-miRNAs: circulating miRNA-based diagnostics for non-cancerous and cancerous diseases. Front Cell Dev Biol (2014) 0.99
Sirtuin regulation in aging and injury. Biochim Biophys Acta (2015) 0.98
Towards a molecular basis of oligometastatic disease: potential role of micro-RNAs. Clin Exp Metastasis (2014) 0.96
SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors. Sci Rep (2015) 0.95
Epigenetics of hepatocellular carcinoma: role of microRNA. World J Gastroenterol (2013) 0.95
Noncoding RNA as therapeutic targets for hepatocellular carcinoma. Semin Liver Dis (2015) 0.94
Emerging role of sirtuins on tumorigenesis: possible link between aging and cancer. BMB Rep (2013) 0.93
Identification of recurrence-related serum microRNAs in hepatocellular carcinoma following hepatectomy. Cancer Biol Ther (2015) 0.93
The p53/microRNA connection in gastrointestinal cancer. Clin Exp Gastroenterol (2014) 0.90
Alcoholic and non-alcoholic steatohepatitis. Exp Mol Pathol (2014) 0.89
MicroRNAs dysregulation in hepatocellular carcinoma: Insights in genomic medicine. World J Hepatol (2015) 0.89
miR-375 suppresses IGF1R expression and contributes to inhibition of cell progression in laryngeal squamous cell carcinoma. Biomed Res Int (2014) 0.87
Application of concave microwells to pancreatic tumor spheroids enabling anticancer drug evaluation in a clinically relevant drug resistance model. PLoS One (2013) 0.87
Regulation of SIRT1 by microRNAs. Mol Cells (2013) 0.86
MiR-222 overexpression promotes proliferation of human hepatocellular carcinoma HepG2 cells by downregulating p27. Int J Clin Exp Med (2014) 0.86
Prognostic marker microRNA-125b inhibits tumorigenic properties of hepatocellular carcinoma cells via suppressing tumorigenic molecule eIF5A2. Dig Dis Sci (2014) 0.85
Molecular pathways: emerging roles of mammalian Sirtuin SIRT7 in cancer. Clin Cancer Res (2014) 0.85
Emerging role of microRNA in hepatocellular carcinoma (Review). Oncol Lett (2014) 0.84
Clinical implications of microRNAs in liver cancer stem cells. Chin J Cancer (2013) 0.83
Hepatitis B Virus X Protein Sensitizes TRAIL-Induced Hepatocyte Apoptosis by Inhibiting the E3 Ubiquitin Ligase A20. PLoS One (2015) 0.83
Genome-Wide Expression of MicroRNAs Is Regulated by DNA Methylation in Hepatocarcinogenesis. Gastroenterol Res Pract (2015) 0.82
SIRTain regulators of premature senescence and accelerated aging. Protein Cell (2015) 0.82
MicroRNA expression analysis in high fat diet-induced NAFLD-NASH-HCC progression: study on C57BL/6J mice. BMC Cancer (2016) 0.81
Sirtuins, a promising target in slowing down the ageing process. Biogerontology (2017) 0.80
The role of microRNAs in hepatocarcinogenesis: current knowledge and future prospects. J Gastroenterol (2013) 0.79
The histone demethylase PHF8 promotes prostate cancer cell growth by activating the oncomiR miR-125b. Onco Targets Ther (2015) 0.79
High expression of Sirt7 served as a predictor of adverse outcome in breast cancer. Int J Clin Exp Pathol (2015) 0.79
Inferring the perturbed microRNA regulatory networks in cancer using hierarchical gene co-expression signatures. PLoS One (2013) 0.79
ERManI is a target of miR-125b and promotes transformation phenotypes in hepatocellular carcinoma (HCC). PLoS One (2013) 0.79
SIRT7 Is Activated by DNA and Deacetylates Histone H3 in the Chromatin Context. ACS Chem Biol (2016) 0.79
SIRT7, H3K18ac, and ELK4 Immunohistochemical Expression in Hepatocellular Carcinoma. J Pathol Transl Med (2016) 0.78
Biogenesis, evolution and functional targets of microRNA-125a. Mol Genet Genomics (2013) 0.78
MiR-125a-5p Decreases the Sensitivity of Treg cells Toward IL-6-Mediated Conversion by Inhibiting IL-6R and STAT3 Expression. Sci Rep (2015) 0.78
Ganoderma lucidum polysaccharide extract inhibits hepatocellular carcinoma growth by downregulating regulatory T cells accumulation and function by inducing microRNA-125b. J Transl Med (2015) 0.77
Histone Deacetylases and Their Regulatory MicroRNAs in Hepatocarcinogenesis. J Korean Med Sci (2015) 0.77
The multifaceted influence of histone deacetylases on DNA damage signalling and DNA repair. Nucleic Acids Res (2016) 0.76
MicroRNA-125a-5p modulates human cervical carcinoma proliferation and migration by targeting ABL2. Drug Des Devel Ther (2015) 0.76
Hypermethylation-Associated Silencing of miR-125a and miR-125b: A Potential Marker in Colorectal Cancer. Dis Markers (2015) 0.76
Stabilization of SIRT7 deacetylase by viral oncoprotein HBx leads to inhibition of growth restrictive RPS7 gene and facilitates cellular transformation. Sci Rep (2015) 0.76
Sirtuins in Cancer: a Balancing Act between Genome Stability and Metabolism. Mol Cells (2015) 0.76
Altered Sirtuin 7 Expression is Associated with Early Stage Breast Cancer. Breast Cancer (Auckl) (2015) 0.76
miR-125b acts as a tumor suppressor in chondrosarcoma cells by the sensitization to doxorubicin through direct targeting the ErbB2-regulated glucose metabolism. Drug Des Devel Ther (2016) 0.76
MiR-125b regulates endometrial receptivity by targeting MMP26 in women undergoing IVF-ET with elevated progesterone on HCG priming day. Sci Rep (2016) 0.75
MicroRNAs in heart failure: Non-coding regulators of metabolic function. Biochim Biophys Acta (2016) 0.75
The seven faces of SIRT7. Transcription (2017) 0.75
TP53/MicroRNA Interplay in Hepatocellular Carcinoma. Int J Mol Sci (2016) 0.75
SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription. Nucleic Acids Res (2017) 0.75
Bioinformatics approach to predict target genes for dysregulated microRNAs in hepatocellular carcinoma: study on a chemically-induced HCC mouse model. BMC Bioinformatics (2015) 0.75
Sirtuins Function as the Modulators in Aging-related Diseases in Common or Respectively. Chin Med J (Engl) (2015) 0.75
Regulation of Serine-Threonine Kinase Akt Activation by NAD(+)-Dependent Deacetylase SIRT7. Cell Rep (2017) 0.75
In Search of New Therapeutic Targets in Obesity Treatment: Sirtuins. Int J Mol Sci (2016) 0.75
SIRT1 and SIRT7 expression in adipose tissues of obese and normal-weight individuals is regulated by microRNAs but not by methylation status. Int J Obes (Lond) (2016) 0.75
Down-regulation of miR-125a-5p is associated with salivary adenoid cystic carcinoma progression via targeting p38/JNK/ERK signal pathway. Am J Transl Res (2017) 0.75
Serum exosomal miR-125b is a novel prognostic marker for hepatocellular carcinoma. Onco Targets Ther (2017) 0.75
Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis. J Biol Chem (2017) 0.75
Development of hepatocellular cancer induced by long term low fat-high carbohydrate diet in a NAFLD/NASH mouse model. Oncotarget (2017) 0.75
MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation (2007) 6.41
PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene (2005) 4.07
High lipophilicity and high daily dose of oral medications are associated with significant risk for drug-induced liver injury. Hepatology (2013) 2.02
Liver-enriched transcription factors in liver function and development. Part I: the hepatocyte nuclear factor network and liver-specific gene expression. Pharmacol Rev (2002) 2.02
Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast carcinomas. Clin Cancer Res (2006) 1.98
Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis. Pharmacol Rev (2008) 1.82
Increased expression of histone deacetylase 2 is found in human gastric cancer. APMIS (2005) 1.77
Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate. Cancer Res (2003) 1.73
Somatic mutations of EGFR gene in squamous cell carcinoma of the head and neck. Clin Cancer Res (2005) 1.70
Drug-induced phospholipidosis. FEBS Lett (2006) 1.69
Expression of viral microRNAs in Epstein-Barr virus-associated gastric carcinoma. J Virol (2006) 1.62
Age-dependent impairment of endothelial progenitor cells is corrected by growth-hormone-mediated increase of insulin-like growth-factor-1. Circ Res (2007) 1.61
Critical enhancements of MRI contrast and hyperthermic effects by dopant-controlled magnetic nanoparticles. Angew Chem Int Ed Engl (2009) 1.57
Inactivating mutations of caspase-8 gene in colorectal carcinomas. Gastroenterology (2003) 1.56
Silicon nanotube battery anodes. Nano Lett (2009) 1.55
Silencing of caspase-8 in murine hepatocellular carcinomas is mediated via methylation of an essential promoter element. Gastroenterology (2005) 1.51
Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling. Hepatology (2005) 1.48
Nuclear factor-eythroid 2-related factor 2 prevents alcohol-induced fulminant liver injury. Gastroenterology (2008) 1.46
Totally laparoscopic total gastrectomy using endoscopic linear stapler: early experiences at one institute. J Laparoendosc Adv Surg Tech A (2012) 1.41
Somatic mutations of the ERBB4 kinase domain in human cancers. Int J Cancer (2006) 1.38
Inactivating mutations of CASP10 gene in non-Hodgkin lymphomas. Blood (2002) 1.30
BRAF and KRAS mutations in stomach cancer. Oncogene (2003) 1.27
Genetic alterations of the KLF6 gene in gastric cancer. Oncogene (2005) 1.26
Expression of xenobiotic metabolizing enzymes in different lung compartments of smokers and nonsmokers. Environ Health Perspect (2006) 1.24
Nod1, a CARD protein, enhances pro-interleukin-1beta processing through the interaction with pro-caspase-1. Biochem Biophys Res Commun (2002) 1.23
ArrayCyGHt: a web application for analysis and visualization of array-CGH data. Bioinformatics (2005) 1.23
Altered expression of the KLF4 in colorectal cancers. Pathol Res Pract (2006) 1.23
CASPASE-8 gene is inactivated by somatic mutations in gastric carcinomas. Cancer Res (2005) 1.20
Mutational analysis of EGFR and K-RAS genes in lung adenocarcinomas. Virchows Arch (2005) 1.20
ERBB2 kinase domain mutation in the lung squamous cell carcinoma. Cancer Lett (2005) 1.19
MiR-145 functions as a tumor suppressor by directly targeting histone deacetylase 2 in liver cancer. Cancer Lett (2013) 1.17
Decreased expression of tumour suppressor Bax-interacting factor-1 (Bif-1), a Bax activator, in gastric carcinomas. Pathology (2006) 1.16
A decade of toxicogenomic research and its contribution to toxicological science. Toxicol Sci (2012) 1.14
Phagocytosis of microglia in the central nervous system diseases. Mol Neurobiol (2014) 1.14
Aberrant regulation of HDAC2 mediates proliferation of hepatocellular carcinoma cells by deregulating expression of G1/S cell cycle proteins. PLoS One (2011) 1.12
Mutations of beta-catenin and AXIN I genes are a late event in human hepatocellular carcinogenesis. Liver Int (2005) 1.11
Immunohistochemical expression of integrins and extracellular matrix proteins in non-small cell lung cancer: correlation with lymph node metastasis. Lung Cancer (2003) 1.11
Caspase-8 gene is frequently inactivated by the frameshift somatic mutation 1225_1226delTG in hepatocellular carcinomas. Oncogene (2005) 1.09
Increased expression of FLIP, an inhibitor of Fas-mediated apoptosis, in stomach cancer. APMIS (2003) 1.08
The kinetics of transcriptomic changes induced by cigarette smoke in rat lungs reveals a specific program of defense, inflammation, and circadian clock gene expression. Toxicol Sci (2006) 1.08
Surfactin from Bacillus subtilis displays anti-proliferative effect via apoptosis induction, cell cycle arrest and survival signaling suppression. FEBS Lett (2007) 1.07
Targeted disruption of Nemo-like kinase inhibits tumor cell growth by simultaneous suppression of cyclin D1 and CDK2 in human hepatocellular carcinoma. J Cell Biochem (2010) 1.07