Published in J Mol Cell Cardiol on January 26, 2005
Myocardial ischemia-reperfusion injury: a neglected therapeutic target. J Clin Invest (2013) 2.83
Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition. Circulation (2008) 2.37
Minocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition. Hepatology (2008) 2.22
The role of mitochondria in protection of the heart by preconditioning. Biochim Biophys Acta (2007) 1.74
Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stress. Am J Physiol Heart Circ Physiol (2007) 1.70
Regulation and pharmacology of the mitochondrial permeability transition pore. Cardiovasc Res (2009) 1.66
Mechanisms of cell death in heart disease. Arterioscler Thromb Vasc Biol (2012) 1.63
Cyclosporine preserves mitochondrial morphology after myocardial ischemia/reperfusion independent of calcineurin inhibition. Ann Thorac Surg (2008) 1.57
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Mitochondrial morphology and cardiovascular disease. Cardiovasc Res (2010) 1.51
Ru360, a specific mitochondrial calcium uptake inhibitor, improves cardiac post-ischaemic functional recovery in rats in vivo. Br J Pharmacol (2006) 1.36
The cardioprotective effect of necrostatin requires the cyclophilin-D component of the mitochondrial permeability transition pore. Cardiovasc Drugs Ther (2007) 1.32
Mitochondria as a drug target in ischemic heart disease and cardiomyopathy. Circ Res (2012) 1.31
Cardiac mitochondria and arrhythmias. Cardiovasc Res (2010) 1.29
Mitochondria and reperfusion injury of the heart--a holey death but not beyond salvation. J Bioenerg Biomembr (2009) 1.23
Cyclosporin A and cardioprotection: from investigative tool to therapeutic agent. Br J Pharmacol (2012) 1.19
Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury. Am J Physiol Heart Circ Physiol (2011) 1.17
Mitochondrial permeability transition in liver ischemia and reperfusion: role of c-Jun N-terminal kinase 2. Transplantation (2008) 1.13
Emerging beneficial roles of sirtuins in heart failure. Basic Res Cardiol (2012) 1.08
Physiological and pathological roles of the mitochondrial permeability transition pore in the heart. Cell Metab (2015) 1.07
Cyclosporine A at reperfusion reduces infarct size in pigs. Cardiovasc Drugs Ther (2010) 1.04
Mitochondrial cyclophilin-D as a potential therapeutic target for post-myocardial infarction heart failure. J Cell Mol Med (2011) 1.03
Diabetic inhibition of preconditioning- and postconditioning-mediated myocardial protection against ischemia/reperfusion injury. Exp Diabetes Res (2011) 1.03
Targeting mitochondrial function for the treatment of acute spinal cord injury. Neurotherapeutics (2011) 1.02
Disrupting the EMMPRIN (CD147)-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion. Arterioscler Thromb Vasc Biol (2011) 1.02
Isoflurane preconditioning elicits competent endogenous mechanisms of protection from oxidative stress in cardiomyocytes derived from human embryonic stem cells. Anesthesiology (2010) 1.01
Cyclosporine-assisted adipose-derived mesenchymal stem cell therapy to mitigate acute kidney ischemia-reperfusion injury. Stem Cell Res Ther (2013) 0.97
Quantifying acute myocardial injury using ratiometric fluorometry. IEEE Trans Biomed Eng (2008) 0.96
Mechanism for resveratrol-induced cardioprotection against reperfusion injury involves glycogen synthase kinase 3beta and mitochondrial permeability transition pore. Eur J Pharmacol (2008) 0.96
Stromal derived factor 1α: a chemokine that delivers a two-pronged defence of the myocardium. Pharmacol Ther (2014) 0.95
Optimising cardioprotection during myocardial ischaemia: targeting potential intracellular pathways with glucagon-like peptide-1. Cardiovasc Diabetol (2014) 0.94
In vivo fluorometric assessment of cyclosporine on mitochondrial function during myocardial ischemia and reperfusion. Ann Thorac Surg (2010) 0.93
Translocation of glycogen synthase kinase-3β (GSK-3β), a trigger of permeability transition, is kinase activity-dependent and mediated by interaction with voltage-dependent anion channel 2 (VDAC2). J Biol Chem (2014) 0.92
A novel role for mitochondrial sphingosine-1-phosphate produced by sphingosine kinase-2 in PTP-mediated cell survival during cardioprotection. Basic Res Cardiol (2011) 0.91
Cyclosporin A in left ventricular remodeling after myocardial infarction. Am J Physiol Heart Circ Physiol (2013) 0.91
Cyclosporin variably and inconsistently reduces infarct size in experimental models of reperfused myocardial infarction: a systematic review and meta-analysis. Br J Pharmacol (2012) 0.91
Bundled postconditioning therapies improve hemodynamics and neurologic recovery after 17 min of untreated cardiac arrest. Resuscitation (2014) 0.90
Postconditioning of sevoflurane and propofol is associated with mitochondrial permeability transition pore. J Zhejiang Univ Sci B (2008) 0.89
Rescue of Heart Failure by Mitochondrial Recovery. Int Neurourol J (2016) 0.89
Combination of cyclosporine and erythropoietin improves brain infarct size and neurological function in rats after ischemic stroke. J Transl Med (2011) 0.87
Translocator protein (18 kDa): a promising therapeutic target and diagnostic tool for cardiovascular diseases. Oxid Med Cell Longev (2012) 0.86
The cardioprotective efficacy of TVP1022 in a rat model of ischaemia/reperfusion. Br J Pharmacol (2011) 0.85
Mechanisms of sudden cardiac death: oxidants and metabolism. Circ Res (2015) 0.83
Infarct size reduction by cyclosporine A at reperfusion involves inhibition of the mitochondrial permeability transition pore but does not improve mitochondrial respiration. Arch Med Sci (2013) 0.82
Nonanticoagulant heparin reduces myocyte Na+ and Ca2+ loading during simulated ischemia and decreases reperfusion injury. Am J Physiol Heart Circ Physiol (2009) 0.82
Novel targets for mitochondrial medicine. Sci Transl Med (2016) 0.82
Alteration of mitochondrial function and cell sensitization to death. J Bioenerg Biomembr (2007) 0.82
Experimental treatments for mitochondrial dysfunction in sepsis: A narrative review. J Res Med Sci (2015) 0.81
Critical role of mitochondrial ROS is dependent on their site of production on the electron transport chain in ischemic heart. Am J Cardiovasc Dis (2016) 0.79
Functional and pharmacological characteristics of permeability transition in isolated human heart mitochondria. PLoS One (2013) 0.79
Astragaloside IV inhibits oxidative stress-induced mitochondrial permeability transition pore opening by inactivating GSK-3β via nitric oxide in H9c2 cardiac cells. Oxid Med Cell Longev (2012) 0.79
A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (Part I - Protection via specific pathways). Med Gas Res (2014) 0.77
Attenuation of skeletal muscle and renal injury to the lower limb following ischemia-reperfusion using mPTP inhibitor NIM-811. PLoS One (2014) 0.77
Coronary flow and reactivity, but not arrhythmia vulnerability, are affected by cardioplegia during cardiopulmonary bypass in piglets. J Cardiothorac Surg (2013) 0.77
Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep (2016) 0.76
Antineoplastic copper coordinated complexes (Casiopeinas) uncouple oxidative phosphorylation and induce mitochondrial permeability transition in cardiac mitochondria and cardiomyocytes. J Bioenerg Biomembr (2016) 0.76
A small-molecule DS44170716 inhibits Ca(2+)-induced mitochondrial permeability transition. Sci Rep (2017) 0.75
Cardiac Specific Overexpression of Mitochondrial Omi/HtrA2 Induces Myocardial Apoptosis and Cardiac Dysfunction. Sci Rep (2016) 0.75
EPO-cyclosporine combination therapy reduced brain infarct area in rat after acute ischemic stroke: role of innate immune-inflammatory response, micro-RNAs and MAPK family signaling pathway. Am J Transl Res (2017) 0.75
Respiratory uncoupling by increased H(+) or K(+) flux is beneficial for heart mitochondrial turnover of reactive oxygen species but not for permeability transition. BMC Cell Biol (2013) 0.75
Cardiomyocyte mitochondria as targets of humoral factors released by remote ischemic preconditioning. Arch Med Sci (2016) 0.75
The Mitochondrial Unfolded Protein Response Protects against Anoxia in Caenorhabditis elegans. PLoS One (2016) 0.75
In vivo opening of the mitochondrial permeability transition pore in a rat model of ventricular fibrillation and closed-chest resuscitation. Am J Transl Res (2017) 0.75
Dose and timing of injections for effective cyclosporine A pretreatment before renal ischemia reperfusion in mice. PLoS One (2017) 0.75
Effect of cyclosporine on reperfusion injury in acute myocardial infarction. N Engl J Med (2008) 9.40
Cyclosporine before PCI in Patients with Acute Myocardial Infarction. N Engl J Med (2015) 5.90
Postconditioning the human heart. Circulation (2005) 4.35
Postconditioning inhibits mitochondrial permeability transition. Circulation (2005) 3.30
Staphylococcus aureus Panton-Valentine leukocidin directly targets mitochondria and induces Bax-independent apoptosis of human neutrophils. J Clin Invest (2005) 2.82
Assessing the multimodal management of advanced solitary fibrous tumors of the pleura in a routine practice setting. J Thorac Oncol (2015) 2.68
Post-conditioning reduces infarct size and edema in patients with ST-segment elevation myocardial infarction. J Am Coll Cardiol (2012) 2.68
Effect of cyclosporine on left ventricular remodeling after reperfused myocardial infarction. J Am Coll Cardiol (2010) 2.54
Idiopathic acute eosinophilic pneumonia: a study of 22 patients. Am J Respir Crit Care Med (2002) 2.35
Inhibition of GSK3beta by postconditioning is required to prevent opening of the mitochondrial permeability transition pore during reperfusion. Circulation (2008) 2.17
Assessment of left ventricular systolic function by deformation imaging derived from speckle tracking: a comparison between 2D and 3D echo modalities. Eur Heart J Cardiovasc Imaging (2013) 2.10
Primary sarcomas of the lung: a clinicopathologic study of 12 cases. Lung Cancer (2002) 2.05
The DNA sequence and analysis of human chromosome 14. Nature (2003) 2.02
Molecular diagnosis of infective endocarditis by PCR amplification and direct sequencing of DNA from valve tissue. J Clin Microbiol (2003) 1.90
Translating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology. Cardiovasc Res (2013) 1.72
New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop. Circulation (2011) 1.66
Long-term benefit of postconditioning. Circulation (2008) 1.65
Quantitative study of nerves of the human left atrium. Heart Rhythm (2005) 1.59
Postconditioning attenuates no-reflow in STEMI patients. Basic Res Cardiol (2013) 1.59
Short- and long-term outcomes of heatstroke following the 2003 heat wave in Lyon, France. Arch Intern Med (2007) 1.58
Home treatment of infection-related acute respiratory failure in kyphoscoliotic patients on long-term mechanical ventilation. Respir Care (2007) 1.56
Cost awareness of physicians in intensive care units: a multicentric national study. Intensive Care Med (2015) 1.43
Mesenchymal stem cell conditioned media attenuates in vitro and ex vivo myocardial reperfusion injury. J Heart Lung Transplant (2010) 1.42
ER stress inhibits neuronal death by promoting autophagy. Autophagy (2012) 1.39
Influence of residual stress/strain on the biomechanical stability of vulnerable coronary plaques: potential impact for evaluating the risk of plaque rupture. Am J Physiol Heart Circ Physiol (2007) 1.38
Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations. Basic Res Cardiol (2010) 1.37
ITMIG consensus statement on the use of the WHO histological classification of thymoma and thymic carcinoma: refined definitions, histological criteria, and reporting. J Thorac Oncol (2014) 1.37
PI 3-kinase regulates the mitochondrial transition pore in controlled reperfusion and postconditioning. Cardiovasc Res (2005) 1.34
Preconditioning delays Ca2+-induced mitochondrial permeability transition. Cardiovasc Res (2004) 1.22
Inhibition of complex I regulates the mitochondrial permeability transition through a phosphate-sensitive inhibitory site masked by cyclophilin D. Biochim Biophys Acta (2012) 1.21
Longitudinal strain quantitates regional right ventricular contractile function. Am J Physiol Heart Circ Physiol (2003) 1.19
Inhibition of mitochondrial permeability transition improves functional recovery and reduces mortality following acute myocardial infarction in mice. Am J Physiol Heart Circ Physiol (2007) 1.18
Cardiac valves in patients with Whipple endocarditis: microbiological, molecular, quantitative histologic, and immunohistochemical studies of 5 patients. J Infect Dis (2004) 1.16
Postconditioning inhibits mPTP opening independent of oxidative phosphorylation and membrane potential. J Mol Cell Cardiol (2009) 1.10
Influence of afterload on left ventricular radial and longitudinal systolic functions: a two-dimensional strain imaging study. Eur J Echocardiogr (2009) 1.10
Diastolic dysfunction in patients with type 2 diabetes mellitus: is it really the first marker of diabetic cardiomyopathy? J Am Soc Echocardiogr (2011) 1.09
Impaired myocardial radial function in asymptomatic patients with type 2 diabetes mellitus: a speckle-tracking imaging study. J Am Soc Echocardiogr (2010) 1.09
Myocardial Salvage, Area at Risk by T2w CMR: The Resolution of the Retrospective Radio Wave Paradigm? J Am Coll Cardiol (2015) 1.08
Inhibition of mitochondrial permeability transition to prevent the post-cardiac arrest syndrome: a pre-clinical study. Eur Heart J (2010) 1.06
Inhibition of mitochondrial permeability transition pore opening: translation to patients. Cardiovasc Res (2009) 1.05
Depressing mitochondria-reticulum interactions protects cardiomyocytes from lethal hypoxia-reoxygenation injury. Circulation (2013) 1.04
p53-PGC-1α pathway mediates oxidative mitochondrial damage and cardiomyocyte necrosis induced by monoamine oxidase-A upregulation: role in chronic left ventricular dysfunction in mice. Antioxid Redox Signal (2012) 1.02
Acute myocardial infarction in mice: assessment of transmurality by strain rate imaging. Am J Physiol Heart Circ Physiol (2007) 1.01
Mitochondrial permeability transition pore and postconditioning. Cardiovasc Res (2006) 1.01
Regional myocardial function after myocardial infarction in mice: a follow-up study by strain rate imaging. J Am Soc Echocardiogr (2009) 0.99
Retracted Glycogen synthase kinase 3β transfers cytoprotective signaling through connexin 43 onto mitochondrial ATP-sensitive K+ channels. Proc Natl Acad Sci U S A (2012) 0.98
Early- and late-onset ventilator-associated pneumonia acquired in the intensive care unit: comparison of risk factors. J Crit Care (2007) 0.97
Neurosensory changes in a human model of endothelin-1 induced pain: a behavioral study. Neurosci Lett (2007) 0.97
Cyclosporine protects the heart during aortic valve surgery. Anesthesiology (2014) 0.97
Determination of the myocardial area at risk with pre- versus post-reperfusion imaging techniques in the pig model. Basic Res Cardiol (2011) 0.97
Trimetazidine inhibits mitochondrial permeability transition pore opening and prevents lethal ischemia-reperfusion injury. J Mol Cell Cardiol (2005) 0.96
Desflurane-induced preconditioning alters calcium-induced mitochondrial permeability transition. Anesthesiology (2004) 0.95
A de novo mutation of the beta cardiac myosin heavy chain gene in an infantile restrictive cardiomyopathy. Congenit Heart Dis (2008) 0.93
Imaging findings in pyogenic ventriculitis. Neurocrit Care (2009) 0.92
Cardioprotection by clopidogrel in acute ST-elevated myocardial infarction patients: a retrospective analysis. Basic Res Cardiol (2012) 0.91
Evaluation of left ventricular function in anesthetized patients using femoral artery dP/dt(max). J Cardiothorac Vasc Anesth (2006) 0.91
The RIPOST-MI study, assessing remote ischemic perconditioning alone or in combination with local ischemic postconditioning in ST-segment elevation myocardial infarction. Basic Res Cardiol (2014) 0.89
Estimating attributable mortality due to nosocomial infections acquired in intensive care units. Infect Control Hosp Epidemiol (2010) 0.89
Evaluation of cyclosporine A in a stroke model in the immature rat brain. Exp Neurol (2010) 0.89
Transdermal buprenorphine - a critical appraisal of its role in pain management. J Pain Res (2009) 0.88
Management of metformin-associated lactic acidosis by continuous renal replacement therapy. PLoS One (2011) 0.88
Ceramide in the antiapoptotic effect of ischemic preconditioning. Am J Physiol Heart Circ Physiol (2003) 0.87
Non-beating HL-1 cells for confocal microscopy: application to mitochondrial functions during cardiac preconditioning. Prog Biophys Mol Biol (2005) 0.86
Comparison of visual scoring and quantitative planimetry methods for estimation of global infarct size on delayed enhanced cardiac MRI and validation with myocardial enzymes. Eur J Radiol (2009) 0.86
Anti-angiogenic and anti-cancer evaluation of betulin nanoemulsion in chicken chorioallantoic membrane and skin carcinoma in Balb/c mice. J Biomed Nanotechnol (2013) 0.86
High prevalence in Switzerland of pure red-cell aplasia due to anti-erythropoietin antibodies in chronic dialysis patients: report of five cases. Nephrol Dial Transplant (2004) 0.85
Increased mitochondrial calcium coexists with decreased reperfusion injury in postconditioned (but not preconditioned) hearts. Am J Physiol Heart Circ Physiol (2007) 0.85
A permeability transition in liposomes induced by the formation of Ca2+/palmitic acid complexes. Biochim Biophys Acta (2003) 0.84
Right isovolumic contraction velocity predicts survival in pulmonary hypertension. J Am Soc Echocardiogr (2012) 0.84
Postconditioning: from the bench to bedside. J Cardiovasc Pharmacol Ther (2010) 0.84
Formation of palmitic acid/Ca2+ complexes in the mitochondrial membrane: a possible role in the cyclosporin-insensitive permeability transition. J Bioenerg Biomembr (2004) 0.84
Morphological and functional aspects of sciatic nerve regeneration after crush injury. Rom J Morphol Embryol (2013) 0.83
Retraction for Rottlaender et al., "Glycogen synthase kinase 3β transfers cytoprotective signaling through connexin 43 onto mitochondrial ATP-sensitive K+ channels". Proc Natl Acad Sci U S A (2012) 0.83
Brain death provokes very acute alteration in myocardial morphology detected by echocardiography: preventive effect of beta-blockers. Transpl Int (2010) 0.83