Published in Am J Physiol Heart Circ Physiol on June 08, 2007
Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition. Cell Cycle (2013) 1.94
Ischemia/reperfusion injury and cardioprotective mechanisms: Role of mitochondria and reactive oxygen species. World J Cardiol (2011) 1.51
The molecular composition of the mitochondrial permeability transition pore. J Mol Cell Cardiol (2009) 1.48
A novel estrogen receptor GPER inhibits mitochondria permeability transition pore opening and protects the heart against ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol (2009) 1.33
Mitochondria as a drug target in ischemic heart disease and cardiomyopathy. Circ Res (2012) 1.31
Mitochondria and reperfusion injury of the heart--a holey death but not beyond salvation. J Bioenerg Biomembr (2009) 1.23
Cyclosporin A and cardioprotection: from investigative tool to therapeutic agent. Br J Pharmacol (2012) 1.19
The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muscle apoptosis and ultrastructural defects in Col6a1-/- myopathic mice. Br J Pharmacol (2009) 1.16
Physiological and pathological roles of the mitochondrial permeability transition pore in the heart. Cell Metab (2015) 1.07
Investigation of Debio 025, a cyclophilin inhibitor, in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy. Br J Pharmacol (2008) 1.07
The paradigm of postconditioning to protect the heart. J Cell Mol Med (2007) 1.07
Early mitochondrial dysfunction in electron transfer activity and reactive oxygen species generation after cardiac arrest. Crit Care Med (2008) 1.06
Mitochondrial cyclophilin-D as a potential therapeutic target for post-myocardial infarction heart failure. J Cell Mol Med (2011) 1.03
Targeting mitochondrial function for the treatment of acute spinal cord injury. Neurotherapeutics (2011) 1.02
Mitochondrial reactive oxygen species at the heart of the matter: new therapeutic approaches for cardiovascular diseases. Circ Res (2015) 1.02
The small chill: mild hypothermia for cardioprotection? Cardiovasc Res (2010) 0.97
Mitochondrial calcium homeostasis as potential target for mitochondrial medicine. Mitochondrion (2011) 0.96
A novel role for mitochondrial sphingosine-1-phosphate produced by sphingosine kinase-2 in PTP-mediated cell survival during cardioprotection. Basic Res Cardiol (2011) 0.91
Cyclosporin A in left ventricular remodeling after myocardial infarction. Am J Physiol Heart Circ Physiol (2013) 0.91
Cyclosporin variably and inconsistently reduces infarct size in experimental models of reperfused myocardial infarction: a systematic review and meta-analysis. Br J Pharmacol (2012) 0.91
Rescue of Heart Failure by Mitochondrial Recovery. Int Neurourol J (2016) 0.89
Inhibition of mitochondrial membrane permeability as a putative pharmacological target for cardioprotection. Curr Med Chem (2009) 0.89
CypD(-/-) hearts have altered levels of proteins involved in Krebs cycle, branch chain amino acid degradation and pyruvate metabolism. J Mol Cell Cardiol (2012) 0.88
Blockade of electron transport at the onset of reperfusion decreases cardiac injury in aged hearts by protecting the inner mitochondrial membrane. J Aging Res (2012) 0.88
Cardioprotection and altered mitochondrial adenine nucleotide transport. Basic Res Cardiol (2009) 0.86
Physiological roles of the mitochondrial permeability transition pore. J Bioenerg Biomembr (2016) 0.84
Endothelial NOS activity and myocardial oxygen metabolism define the salvageable ischemic time window for ischemic postconditioning. Am J Physiol Heart Circ Physiol (2011) 0.84
Mechanisms of sudden cardiac death: oxidants and metabolism. Circ Res (2015) 0.83
Novel targets for mitochondrial medicine. Sci Transl Med (2016) 0.82
Cell death disguised: The mitochondrial permeability transition pore as the c-subunit of the F(1)F(O) ATP synthase. Pharmacol Res (2015) 0.80
Heme oxygenase-1 regulates mitochondrial quality control in the heart. JCI Insight (2016) 0.80
Modulation of intracellular calcium waves and triggered activities by mitochondrial ca flux in mouse cardiomyocytes. PLoS One (2013) 0.80
Distinct cardioprotective mechanisms of immediate, early and delayed ischaemic postconditioning. Basic Res Cardiol (2014) 0.78
The SR/ER-mitochondria calcium crosstalk is regulated by GSK3β during reperfusion injury. Cell Death Differ (2015) 0.76
In vivo opening of the mitochondrial permeability transition pore in a rat model of ventricular fibrillation and closed-chest resuscitation. Am J Transl Res (2017) 0.75
Effect of cyclosporine on reperfusion injury in acute myocardial infarction. N Engl J Med (2008) 9.40
Cyclosporine before PCI in Patients with Acute Myocardial Infarction. N Engl J Med (2015) 5.90
Postconditioning the human heart. Circulation (2005) 4.35
Postconditioning inhibits mitochondrial permeability transition. Circulation (2005) 3.30
Current and evolving echocardiographic techniques for the quantitative evaluation of cardiac mechanics: ASE/EAE consensus statement on methodology and indications endorsed by the Japanese Society of Echocardiography. J Am Soc Echocardiogr (2011) 2.97
Risk of embolism and death in infective endocarditis: prognostic value of echocardiography: a prospective multicenter study. Circulation (2005) 2.69
Post-conditioning reduces infarct size and edema in patients with ST-segment elevation myocardial infarction. J Am Coll Cardiol (2012) 2.68
Effect of cyclosporine on left ventricular remodeling after reperfused myocardial infarction. J Am Coll Cardiol (2010) 2.54
Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy. Nat Med (2008) 2.49
The cyclophilin inhibitor Debio-025 shows potent anti-hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus. Hepatology (2008) 2.24
Inhibition of GSK3beta by postconditioning is required to prevent opening of the mitochondrial permeability transition pore during reperfusion. Circulation (2008) 2.17
Assessment of left ventricular systolic function by deformation imaging derived from speckle tracking: a comparison between 2D and 3D echo modalities. Eur Heart J Cardiovasc Imaging (2013) 2.10
Noninvasive assessment of murine pulmonary arterial pressure: validation and application to models of pulmonary hypertension. Circ Cardiovasc Imaging (2009) 2.05
The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitro. Hepatology (2006) 1.99
Evaluation of a cyclophilin inhibitor in hepatitis C virus-infected chimeric mice in vivo. Hepatology (2007) 1.95
Specific inhibition of the mitochondrial permeability transition prevents lethal reperfusion injury. J Mol Cell Cardiol (2005) 1.92
A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes. J Biol Chem (2006) 1.75
The cyclophilin inhibitor Debio 025 combined with PEG IFNalpha2a significantly reduces viral load in treatment-naïve hepatitis C patients. Hepatology (2009) 1.75
Translating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology. Cardiovasc Res (2013) 1.72
Endocarditis in the elderly: clinical, echocardiographic, and prognostic features. Eur Heart J (2003) 1.71
Toward understanding response to cardiac resynchronization therapy: left ventricular dyssynchrony is only one of multiple mechanisms. Eur Heart J (2008) 1.66
New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop. Circulation (2011) 1.66
Long-term benefit of postconditioning. Circulation (2008) 1.65
Tissue Doppler imaging detects early asymptomatic myocardial abnormalities in a dog model of Duchenne's cardiomyopathy. Eur Heart J (2004) 1.65
DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A. PLoS One (2010) 1.59
Alterations of systolic left ventricular twist after acute myocardial infarction. Am J Physiol Heart Circ Physiol (2002) 1.59
Postconditioning attenuates no-reflow in STEMI patients. Basic Res Cardiol (2013) 1.59
The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro. Hum Mol Genet (2002) 1.58
Activation of epithelial sodium channels by mouse channel activating proteases (mCAP) expressed in Xenopus oocytes requires catalytic activity of mCAP3 and mCAP2 but not mCAP1. J Am Soc Nephrol (2006) 1.48
Inhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agent. Antimicrob Agents Chemother (2008) 1.46
Naturally occurring capsid substitutions render HIV-1 cyclophilin A independent in human cells and TRIM-cyclophilin-resistant in Owl monkey cells. J Biol Chem (2005) 1.45
Mesenchymal stem cell conditioned media attenuates in vitro and ex vivo myocardial reperfusion injury. J Heart Lung Transplant (2010) 1.42
Cardiac magnetic resonance demonstrates myocardial oedema in remote tissue early after reperfused myocardial infarction. Arch Cardiovasc Dis (2009) 1.40
ER stress inhibits neuronal death by promoting autophagy. Autophagy (2012) 1.39
Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations. Basic Res Cardiol (2010) 1.37
In vitro and in vivo regulation of transepithelial lung alveolar sodium transport by serine proteases. Am J Physiol Lung Cell Mol Physiol (2005) 1.34
PI 3-kinase regulates the mitochondrial transition pore in controlled reperfusion and postconditioning. Cardiovasc Res (2005) 1.34
The nonimmunosuppressive cyclosporin analogs NIM811 and UNIL025 display nanomolar potencies on permeability transition in brain-derived mitochondria. J Bioenerg Biomembr (2004) 1.27
Acute improvement in global and regional left ventricular systolic function after percutaneous heart valve implantation in patients with symptomatic aortic stenosis. Circulation (2004) 1.23
Preconditioning delays Ca2+-induced mitochondrial permeability transition. Cardiovasc Res (2004) 1.22
Inhibition of complex I regulates the mitochondrial permeability transition through a phosphate-sensitive inhibitory site masked by cyclophilin D. Biochim Biophys Acta (2012) 1.21
ENaC-mediated alveolar fluid clearance and lung fluid balance depend on the channel-activating protease 1. EMBO Mol Med (2010) 1.20
Longitudinal strain quantitates regional right ventricular contractile function. Am J Physiol Heart Circ Physiol (2003) 1.19
Debio 025, a cyclophilin binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically targeted antiviral therapy for HCV (STAT-C) inhibitors. Antimicrob Agents Chemother (2008) 1.18
Quantitative assessment of regional myocardial function in mice by tissue Doppler imaging: comparison with hemodynamics and sonomicrometry. Circulation (2005) 1.14
Postconditioning inhibits mPTP opening independent of oxidative phosphorylation and membrane potential. J Mol Cell Cardiol (2009) 1.10
In vivo characterization of murine myocardial perfusion with myocardial contrast echocardiography: validation and application in nitric oxide synthase 3 deficient mice. Circulation (2007) 1.10
Influence of afterload on left ventricular radial and longitudinal systolic functions: a two-dimensional strain imaging study. Eur J Echocardiogr (2009) 1.10
Cardiac and respiratory self-gated cine MRI in the mouse: comparison between radial and rectilinear techniques at 7T. Magn Reson Med (2007) 1.10
Diastolic dysfunction in patients with type 2 diabetes mellitus: is it really the first marker of diabetic cardiomyopathy? J Am Soc Echocardiogr (2011) 1.09
Cyclosporine increases human immunodeficiency virus type 1 vector transduction of primary mouse cells. J Virol (2006) 1.09
Impaired myocardial radial function in asymptomatic patients with type 2 diabetes mellitus: a speckle-tracking imaging study. J Am Soc Echocardiogr (2010) 1.09
Myocardial Salvage, Area at Risk by T2w CMR: The Resolution of the Retrospective Radio Wave Paradigm? J Am Coll Cardiol (2015) 1.08
Inhibition of mitochondrial permeability transition to prevent the post-cardiac arrest syndrome: a pre-clinical study. Eur Heart J (2010) 1.06
Inhibition of mitochondrial permeability transition pore opening: translation to patients. Cardiovasc Res (2009) 1.05
Systolic myocardial dysfunction in patients with type 2 diabetes mellitus: identification at MR imaging with cine displacement encoding with stimulated echoes. Radiology (2012) 1.04
Depressing mitochondria-reticulum interactions protects cardiomyocytes from lethal hypoxia-reoxygenation injury. Circulation (2013) 1.04
p53-PGC-1α pathway mediates oxidative mitochondrial damage and cardiomyocyte necrosis induced by monoamine oxidase-A upregulation: role in chronic left ventricular dysfunction in mice. Antioxid Redox Signal (2012) 1.02
Activation of lung p53 by Nutlin-3a prevents and reverses experimental pulmonary hypertension. Circulation (2013) 1.01
Acute myocardial infarction in mice: assessment of transmurality by strain rate imaging. Am J Physiol Heart Circ Physiol (2007) 1.01
Mitochondrial permeability transition pore and postconditioning. Cardiovasc Res (2006) 1.01
Validation of noninvasive measurements of cardiac output in mice using echocardiography. J Am Soc Echocardiogr (2011) 1.00
The European CRT Survey: 1 year (9-15 months) follow-up results. Eur J Heart Fail (2012) 0.99
Regional myocardial function after myocardial infarction in mice: a follow-up study by strain rate imaging. J Am Soc Echocardiogr (2009) 0.99
Increased poliovirus-specific intestinal antibody response coincides with promotion of Bifidobacterium longum-infantis and Bifidobacterium breve in infants: a randomized, double-blind, placebo-controlled trial. Pediatr Res (2004) 0.99
Retracted Glycogen synthase kinase 3β transfers cytoprotective signaling through connexin 43 onto mitochondrial ATP-sensitive K+ channels. Proc Natl Acad Sci U S A (2012) 0.98
Cyclosporine protects the heart during aortic valve surgery. Anesthesiology (2014) 0.97
Successful cardiac resynchronization therapy after cardiac surgery. Anesth Analg (2007) 0.97
Right and left ventricular adaptation to hypoxia: a tissue Doppler imaging study. Am J Physiol Heart Circ Physiol (2005) 0.97
Diastolic asynchrony is more frequent than systolic asynchrony in dilated cardiomyopathy and is less improved by cardiac resynchronization therapy. J Am Coll Cardiol (2005) 0.97
Can changes in systolic longitudinal deformation quantify regional myocardial function after an acute infarction? An ultrasonic strain rate and strain study. J Am Soc Echocardiogr (2002) 0.97
Determination of the myocardial area at risk with pre- versus post-reperfusion imaging techniques in the pig model. Basic Res Cardiol (2011) 0.97