Published in J Neurosci Res on April 01, 2005
Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis. J Clin Invest (2006) 2.56
Citrullination is an inflammation-dependent process. Ann Rheum Dis (2006) 2.25
Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential. Curr Opin Drug Discov Devel (2009) 1.83
Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3. Biochemistry (2010) 1.66
Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor. Am J Physiol Gastrointest Liver Physiol (2011) 1.61
Citrullination of myofilament proteins in heart failure. Cardiovasc Res (2015) 1.40
Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors. ACS Chem Biol (2011) 1.25
The protein arginine deiminases: Structure, function, inhibition, and disease. Biopolymers (2013) 1.18
An improved synthesis of haloaceteamidine-based inactivators of protein arginine deiminase 4 (PAD4). Tetrahedron Lett (2008) 1.13
Potential role for peptidylarginine deiminase 2 (PAD2) in citrullination of canine mammary epithelial cell histones. PLoS One (2010) 1.12
Potential role for PAD2 in gene regulation in breast cancer cells. PLoS One (2012) 1.08
Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis? Arthritis Res Ther (2010) 1.03
Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis. Dis Model Mech (2012) 0.97
Accumulation of citrullinated proteins by up-regulated peptidylarginine deiminase 2 in brains of scrapie-infected mice: a possible role in pathogenesis. Am J Pathol (2008) 0.97
Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling. Arthritis Rheum (2013) 0.96
Biomarkers in inflammatory bowel diseases: current status and proteomics identification strategies. World J Gastroenterol (2014) 0.93
Seeing citrulline: development of a phenylglyoxal-based probe to visualize protein citrullination. J Am Chem Soc (2012) 0.93
Design, synthesis, and biological evaluation of tetrazole analogs of Cl-amidine as protein arginine deiminase inhibitors. J Med Chem (2015) 0.90
Demonstration of extracellular peptidylarginine deiminase (PAD) activity in synovial fluid of patients with rheumatoid arthritis using a novel assay for citrullination of fibrinogen. Arthritis Res Ther (2014) 0.88
Neutral loss of isocyanic acid in peptide CID spectra: a novel diagnostic marker for mass spectrometric identification of protein citrullination. J Am Soc Mass Spectrom (2008) 0.88
Autoantibodies to posttranslational modifications in rheumatoid arthritis. Mediators Inflamm (2014) 0.86
Vimentin is involved in peptidylarginine deiminase 2-induced apoptosis of activated Jurkat cells. Mol Cells (2014) 0.86
PADI4 and tumourigenesis. Cancer Cell Int (2010) 0.85
Accumulation of glial fibrillary acidic protein and histone H4 in brain storage bodies of Tibetan terriers with hereditary neuronal ceroid lipofuscinosis. J Inherit Metab Dis (2007) 0.82
Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice. BMC Musculoskelet Disord (2016) 0.80
Peptidylarginine deiminase and protein citrullination in prion diseases: strong evidence of neurodegeneration. Prion (2012) 0.79
Protein Arginine Deiminases and Associated Citrullination: Physiological Functions and Diseases Associated with Dysregulation. Curr Drug Targets (2015) 0.79
Retinal deimination and PAD2 levels in retinas from donors with age-related macular degeneration (AMD). Exp Eye Res (2013) 0.77
Dual immunofluorescence study of citrullinated proteins in Alzheimer diseased frontal cortex. Neurosci Lett (2013) 0.77
Is anti-cyclic citrullinated Peptide antibody a good value biomarker for Alzheimer disease? Int J Prev Med (2013) 0.75
The Immune Syntax Revisited: Opening New Windows on Language Evolution. Front Mol Neurosci (2016) 0.75
Protective effect of Cl-amidine against CLP-induced lethal septic shock in mice. Sci Rep (2016) 0.75
NETosis in Alzheimer's Disease. Front Immunol (2017) 0.75
Protein Citrullination: A Proposed Mechanism for Pathology in Traumatic Brain Injury. Front Neurol (2015) 0.75
Citrullination of glial intermediate filaments is an early response in retinal injury. Mol Vis (2016) 0.75
Reduced glutathione as a physiological co-activator in the activation of peptidylarginine deiminase. Arthritis Res Ther (2016) 0.75
Interrogation of the Active Sites of Protein Arginine Deiminases (PAD1, -2, and -4) Using Designer Probes. ACS Med Chem Lett (2013) 0.75
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathol (2007) 8.10
Senescence marker protein-30 protects mice lungs from oxidative stress, aging, and smoking. Am J Respir Crit Care Med (2006) 2.87
Prospective 10-year surveillance of human prion diseases in Japan. Brain (2010) 2.41
Spinocerebellar ataxia type 31 is associated with "inserted" penta-nucleotide repeats containing (TGGAA)n. Am J Hum Genet (2009) 1.96
Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity. Proc Natl Acad Sci U S A (2008) 1.86
Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson's disease. Hum Mol Genet (2006) 1.83
Complete genetic correction of ips cells from Duchenne muscular dystrophy. Mol Ther (2009) 1.74
Granular tau oligomers as intermediates of tau filaments. Biochemistry (2007) 1.67
Accumulation of phosphorylated alpha-synuclein in aging human brain. J Neuropathol Exp Neurol (2003) 1.59
Senescence marker protein-30/gluconolactonase deletion worsens glucose tolerance through impairment of acute insulin secretion. Endocrinology (2009) 1.55
Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene. Biochem Biophys Res Commun (2003) 1.53
Antioxidant, EUK-8, prevents murine dilated cardiomyopathy. Circ J (2009) 1.52
Validation of cardiac (123)I-MIBG scintigraphy in patients with Parkinson's disease who were diagnosed with dopamine PET. Eur J Nucl Med Mol Imaging (2010) 1.51
Lewy body-related alpha-synucleinopathy in aging. J Neuropathol Exp Neurol (2004) 1.49
Molecular evolution of nucleoside diphosphate kinase genes: conserved core structures and multiple-layered regulatory regions. J Bioenerg Biomembr (2003) 1.49
Increased levels of granular tau oligomers: an early sign of brain aging and Alzheimer's disease. Neurosci Res (2006) 1.49
Prion-like properties of pathological TDP-43 aggregates from diseased brains. Cell Rep (2013) 1.49
The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation. Cell Cycle (2007) 1.45
Utilization behavior as a white matter disconnection syndrome. Cortex (2002) 1.43
Novel use for an EGFR mutation-specific antibody in discriminating lung adenocarcinoma from reactive pneumocyte hyperplasia. Histopathology (2015) 1.41
Senescence marker protein 30 functions as gluconolactonase in L-ascorbic acid biosynthesis, and its knockout mice are prone to scurvy. Proc Natl Acad Sci U S A (2006) 1.37
Proteomic analysis of human brain identifies alpha-enolase as a novel autoantigen in Hashimoto's encephalopathy. FEBS Lett (2002) 1.37
Apoptosis accompanied by up-regulation of TNF-alpha death pathway genes in the brain of Niemann-Pick type C disease. Mol Genet Metab (2005) 1.32
Senescence marker protein-30 knockout mouse liver is highly susceptible to tumor necrosis factor-alpha- and Fas-mediated apoptosis. Am J Pathol (2002) 1.30
Hydrogen-rich pure water prevents superoxide formation in brain slices of vitamin C-depleted SMP30/GNL knockout mice. Biochem Biophys Res Commun (2008) 1.29
An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies. Acta Neuropathol (2006) 1.24
Neuropathology of mild cognitive impairment. Neuropathology (2007) 1.23
Staging of argyrophilic grains: an age-associated tauopathy. J Neuropathol Exp Neurol (2004) 1.23
Spliceosome integrity is defective in the motor neuron diseases ALS and SMA. EMBO Mol Med (2013) 1.22
Neuroprotective effect of an antioxidant, lutein, during retinal inflammation. Invest Ophthalmol Vis Sci (2008) 1.21
SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer disease. J Biol Chem (2011) 1.19
Lewy body pathology involves cutaneous nerves. J Neuropathol Exp Neurol (2008) 1.19
Impaired motor coordination in mice lacking neural recognition molecule NB-3 of the contactin/F3 subgroup. J Neurobiol (2003) 1.17
Niemann-Pick type C disease: accelerated neurofibrillary tangle formation and amyloid beta deposition associated with apolipoprotein E epsilon 4 homozygosity. Ann Neurol (2002) 1.16
Incidence and extent of Lewy body-related alpha-synucleinopathy in aging human olfactory bulb. J Neuropathol Exp Neurol (2008) 1.15
Induction of myasthenia by immunization against muscle-specific kinase. J Clin Invest (2006) 1.13
SMP30 deficiency in mice causes an accumulation of neutral lipids and phospholipids in the liver and shortens the life span. Biochem Biophys Res Commun (2004) 1.12
Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid. Proc Natl Acad Sci U S A (2007) 1.11
Development of an open source laboratory information management system for 2-D gel electrophoresis-based proteomics workflow. BMC Bioinformatics (2006) 1.10
Neuropathological diagnostic criteria for Alzheimer's disease. Neuropathology (2004) 1.09
Proteomic identification of differentially-expressed genes in human gastric carcinomas. Proteomics (2005) 1.07
Prospective evaluation of selection criteria for active surveillance in Japanese patients with stage T1cN0M0 prostate cancer. Jpn J Clin Oncol (2008) 1.06
Proteomic analysis of two types of exosomes in human whole saliva. Biol Pharm Bull (2011) 1.06
Enhanced antigen retrieval of amyloid β immunohistochemistry: re-evaluation of amyloid β pathology in Alzheimer disease and its mouse model. J Histochem Cytochem (2012) 1.04
Aberrant phosphorylation of alpha-synuclein in human Niemann-Pick type C1 disease. J Neuropathol Exp Neurol (2004) 1.03
Possibility for neurogenesis in substantia nigra of parkinsonian brain. Ann Neurol (2005) 1.03
Human peptidylarginine deiminase type II: molecular cloning, gene organization, and expression in human skin. Arch Biochem Biophys (2002) 1.02
Interleukin-1 beta up-regulates TACE to enhance alpha-cleavage of APP in neurons: resulting decrease in Abeta production. J Neurochem (2007) 1.02
The TRK-fused gene is mutated in hereditary motor and sensory neuropathy with proximal dominant involvement. Am J Hum Genet (2012) 1.02
SMP30 deficiency causes increased oxidative stress in brain. Mech Ageing Dev (2006) 1.01
Basophilic inclusion body disease and neuronal intermediate filament inclusion disease: a comparative clinicopathological study. Acta Neuropathol (2007) 1.01
Senescence marker protein-30 is a unique enzyme that hydrolyzes diisopropyl phosphorofluoridate in the liver. FEBS Lett (2004) 0.99
Analysis of glycopeptides using lectin affinity chromatography with MALDI-TOF mass spectrometry. Anal Chem (2008) 0.99
SIRT2 downregulation confers resistance to microtubule inhibitors by prolonging chronic mitotic arrest. Cell Cycle (2009) 0.97
Accumulation of citrullinated proteins by up-regulated peptidylarginine deiminase 2 in brains of scrapie-infected mice: a possible role in pathogenesis. Am J Pathol (2008) 0.97
Analysis of the adrenal gland is useful for evaluating pathology of the peripheral autonomic nervous system in lewy body disease. J Neuropathol Exp Neurol (2007) 0.97
Modulation of gene expression of SMP-30 by LPS and calorie restriction during aging process. Exp Gerontol (2004) 0.97
Redox regulation in radiation-induced cytochrome c release from mitochondria of human lung carcinoma A549 cells. Cancer Lett (2008) 0.97
Development of a high-throughput microarray-based resequencing system for neurological disorders and its application to molecular genetics of amyotrophic lateral sclerosis. Arch Neurol (2008) 0.97
Pathological findings at radical prostatectomy in Japanese prospective active surveillance cohort. Jpn J Clin Oncol (2010) 0.96
Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease. EMBO Mol Med (2012) 0.96
Ascorbic acid depletion enhances expression of the sodium-dependent vitamin C transporters, SVCT1 and SVCT2, and uptake of ascorbic acid in livers of SMP30/GNL knockout mice. Arch Biochem Biophys (2010) 0.96
Extensive deamidation at asparagine residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer's disease brain. Acta Neuropathol Commun (2013) 0.95
Complete lack of vitamin C intake generates pulmonary emphysema in senescence marker protein-30 knockout mice. Am J Physiol Lung Cell Mol Physiol (2010) 0.95
Biological role of lutein in the light-induced retinal degeneration. J Nutr Biochem (2011) 0.94
Evidence for a role of Collapsin response mediator protein-2 in signaling pathways that regulate the proliferation of non-neuronal cells. Biochem Biophys Res Commun (2006) 0.93
Beta-site APP cleaving enzyme 1 (BACE1) is increased in remaining neurons in Alzheimer's disease brains. Neurosci Res (2005) 0.93
Developments of geriatric autopsy database and Internet-based database of Japanese single nucleotide polymorphisms for geriatric research (JG-SNP). Mech Ageing Dev (2004) 0.92
Characterization of the protease activity that cleaves the extracellular domain of beta-dystroglycan. Biochem Biophys Res Commun (2006) 0.92
Antibodies against muscle-specific kinase impair both presynaptic and postsynaptic functions in a murine model of myasthenia gravis. Am J Pathol (2011) 0.92
Determination of 1-deoxynojirimycin in mulberry leaves using hydrophilic interaction chromatography with evaporative light scattering detection. J Agric Food Chem (2004) 0.92
Monoclonal antibody against the turn of the 42-residue amyloid β-protein at positions 22 and 23. ACS Chem Neurosci (2010) 0.92
Evaluation of SLC20A2 mutations that cause idiopathic basal ganglia calcification in Japan. Neurology (2014) 0.92
Role of DNA methylation in transcription of human endogenous retrovirus in the pathogenesis of systemic lupus erythematosus. J Rheumatol (2002) 0.91
Vitamin C depletion increases superoxide generation in brains of SMP30/GNL knockout mice. Biochem Biophys Res Commun (2008) 0.91
The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis. Mol Brain (2013) 0.91
Time course of vitamin C distribution and absorption after oral administration in SMP30/GNL knockout mice. Nutrition (2010) 0.91
Autotaxin expression is enhanced in frontal cortex of Alzheimer-type dementia patients. Neurosci Lett (2006) 0.91
Mitochondrial reactive oxygen species generation by the SDHC V69E mutation causes low birth weight and neonatal growth retardation. Mitochondrion (2010) 0.91
Selective loss of Purkinje cells in a patient with anti-glutamic acid decarboxylase antibody-associated cerebellar ataxia. J Neurol Neurosurg Psychiatry (2006) 0.91