Published in PLoS One on July 26, 2010
VDR/RXR and TCF4/β-catenin cistromes in colonic cells of colorectal tumor origin: impact on c-FOS and c-MYC gene expression. Mol Endocrinol (2011) 1.46
Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation. Proc Natl Acad Sci U S A (2012) 1.35
Peptidylarginine deiminases in citrullination, gene regulation, health and pathogenesis. Biochim Biophys Acta (2013) 1.20
The protein arginine deiminases: Structure, function, inhibition, and disease. Biopolymers (2013) 1.18
Identification of PADI2 as a potential breast cancer biomarker and therapeutic target. BMC Cancer (2012) 1.18
Potential role of peptidylarginine deiminase enzymes and protein citrullination in cancer pathogenesis. Biochem Res Int (2012) 1.08
Potential role for PAD2 in gene regulation in breast cancer cells. PLoS One (2012) 1.08
Identification of macrophage extracellular trap-like structures in mammary gland adipose tissue: a preliminary study. Front Immunol (2013) 1.01
Chemical biology of protein arginine modifications in epigenetic regulation. Chem Rev (2015) 0.99
Potential role for PADI-mediated histone citrullination in preimplantation development. BMC Dev Biol (2012) 0.95
D-amino acid based protein arginine deiminase inhibitors: Synthesis, pharmacokinetics, and in cellulo efficacy. ACS Med Chem Lett (2012) 0.86
Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanism. Biochemistry (2014) 0.85
Protein Arginine Methylation and Citrullination in Epigenetic Regulation. ACS Chem Biol (2015) 0.81
A FluoPol-ABPP PAD2 high-throughput screen identifies the first calcium site inhibitor targeting the PADs. ACS Chem Biol (2014) 0.81
Chemical Proteomic Platform To Identify Citrullinated Proteins. ACS Chem Biol (2015) 0.79
A Critical Reappraisal of Neutrophil Extracellular Traps and NETosis Mimics Based on Differential Requirements for Protein Citrullination. Front Immunol (2016) 0.78
PADI2 gene confers susceptibility to breast cancer and plays tumorigenic role via ACSL4, BINC3 and CA9 signaling. Cancer Cell Int (2016) 0.78
A comprehensive view of the epigenetic landscape. Part II: Histone post-translational modification, nucleosome level, and chromatin regulation by ncRNAs. Neurotox Res (2014) 0.77
Peptidylarginine Deiminase 3 (PAD3) Is Upregulated by Prolactin Stimulation of CID-9 Cells and Expressed in the Lactating Mouse Mammary Gland. PLoS One (2016) 0.77
Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development. Sci Rep (2016) 0.75
A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22. JCI Insight (2016) 0.75
Citrullination/Methylation Crosstalk on Histone H3 Regulates ER-Target Gene Transcription. ACS Chem Biol (2017) 0.75
GnRH Stimulates Peptidylarginine Deiminase Catalyzed Histone Citrullination in Gonadotrope Cells. Mol Endocrinol (2016) 0.75
PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease. Bioessays (2003) 5.04
Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages. Ann Rheum Dis (2004) 2.82
Development and evaluation of canine reference genes for accurate quantification of gene expression. Anal Biochem (2006) 2.07
Citrullination: a posttranslational modification in health and disease. Int J Biochem Cell Biol (2006) 2.05
Citrullination of synovial proteins in murine models of rheumatoid arthritis. Arthritis Rheum (2003) 1.88
Expression of peptidylarginine deiminase type 4 (PAD4) in various tumors. Mol Carcinog (2006) 1.70
Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease. J Neurosci Res (2005) 1.57
Detection of citrulline residues in deiminated proteins on polyvinylidene difluoride membrane. Anal Biochem (1992) 1.43
Comparative expression pathway analysis of human and canine mammary tumors. BMC Genomics (2009) 1.35
Dynamic alterations of specific histone modifications during early murine development. J Cell Sci (2004) 1.30
Validity of mouse mammary tumour models for human breast cancer: comparative pathology. Microsc Res Tech (2001) 1.20
Myelin localization of peptidylarginine deiminases 2 and 4: comparison of PAD2 and PAD4 activities. Lab Invest (2008) 1.15
Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system. Dis Model Mech (2008) 1.14
p63: a novel myoepithelial cell marker in canine mammary tissues. Vet Pathol (2003) 1.12
Comparative pathology of mammary gland cancers in domestic and wild animals. Breast Dis (2007) 0.99
Peptidylarginine deiminase in rat pituitary: sex difference, estrous cycle-related changes, and estrogen dependence. Endocrinology (1989) 0.96
Peptidylarginine deiminase of the mouse. Distribution, properties, and immunocytochemical localization. J Biol Chem (1989) 0.96
Expression of the oncogene c-erbB-2 in canine mammary cancers and tumor-derived cell lines. Am J Vet Res (1996) 0.91
Expression of peptidylarginine deiminase in the uterine epithelial cells of mouse is dependent on estrogen. J Biol Chem (1992) 0.91
Estrous cycle-dependent histology and review of sex steroid receptor expression in dog reproductive tissues and mammary gland and associated hormone levels. Birth Defects Res B Dev Reprod Toxicol (2007) 0.89
Biologic properties of cell lines derived from canine mammary carcinomas. J Natl Cancer Inst (1986) 0.85
Changes in oestrogen, progesterone and epidermal growth factor receptor concentrations and affinities during the oestrous cycle in the normal mammary gland and uterus of dogs. Vet Res Commun (1995) 0.80
Human PAD4 regulates histone arginine methylation levels via demethylimination. Science (2004) 5.46
Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J Cell Biol (2009) 5.27
Regulation of coactivator complex assembly and function by protein arginine methylation and demethylimination. Proc Natl Acad Sci U S A (2005) 2.40
Augmentation of tissue transglutaminase expression and activation by epidermal growth factor inhibit doxorubicin-induced apoptosis in human breast cancer cells. J Biol Chem (2004) 1.39
ePAD, an oocyte and early embryo-abundant peptidylarginine deiminase-like protein that localizes to egg cytoplasmic sheets. Dev Biol (2003) 1.37
Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation. Proc Natl Acad Sci U S A (2012) 1.35
Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cells. PLoS Genet (2011) 1.33
Dynamic alterations of specific histone modifications during early murine development. J Cell Sci (2004) 1.30
Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors. ACS Chem Biol (2011) 1.25
CABYR, a novel calcium-binding tyrosine phosphorylation-regulated fibrous sheath protein involved in capacitation. Dev Biol (2002) 1.25
Role for PADI6 and the cytoplasmic lattices in ribosomal storage in oocytes and translational control in the early mouse embryo. Development (2008) 1.22
Identification of PADI2 as a potential breast cancer biomarker and therapeutic target. BMC Cancer (2012) 1.18
SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoa. Biol Reprod (2002) 1.13
Activation of the Ras-ERK pathway inhibits retinoic acid-induced stimulation of tissue transglutaminase expression in NIH3T3 cells. J Biol Chem (2003) 1.11
SAMP14, a novel, acrosomal membrane-associated, glycosylphosphatidylinositol-anchored member of the Ly-6/urokinase-type plasminogen activator receptor superfamily with a role in sperm-egg interaction. J Biol Chem (2003) 1.09
Oolemmal proteomics--identification of highly abundant heat shock proteins and molecular chaperones in the mature mouse egg and their localization on the plasma membrane. Reprod Biol Endocrinol (2003) 1.08
Potential role of peptidylarginine deiminase enzymes and protein citrullination in cancer pathogenesis. Biochem Res Int (2012) 1.08
Centromeric protein CENP-B proteasomal degradation induced by the viral protein ICP0. FEBS Lett (2007) 1.08
Potential role for PAD2 in gene regulation in breast cancer cells. PLoS One (2012) 1.08
Role for peptidylarginine deiminase enzymes in disease and female reproduction. J Reprod Dev (2012) 1.04
Identification of macrophage extracellular trap-like structures in mammary gland adipose tissue: a preliminary study. Front Immunol (2013) 1.01
Potential role for MATER in cytoplasmic lattice formation in murine oocytes. PLoS One (2010) 1.01
Use of proteomics to identify highly abundant maternal factors that drive the egg-to-embryo transition. Reproduction (2010) 1.00
Mouse SLLP1, a sperm lysozyme-like protein involved in sperm-egg binding and fertilization. Dev Biol (2005) 0.99
Regulation of mouse oocyte microtubule and organelle dynamics by PADI6 and the cytoplasmic lattices. Dev Biol (2010) 0.98
Structural requirements for the inhibitory action of the CD9 large extracellular domain in sperm/oocyte binding and fusion. Biochem Biophys Res Commun (2003) 0.97
Potential role for PADI-mediated histone citrullination in preimplantation development. BMC Dev Biol (2012) 0.95
Transient estrogen receptor binding and p300 redistribution support a squelching mechanism for estradiol-repressed genes. Mol Endocrinol (2014) 0.92
Design, synthesis, and biological evaluation of tetrazole analogs of Cl-amidine as protein arginine deiminase inhibitors. J Med Chem (2015) 0.90
Cross-sectional study to investigate the association between vitamin D status and cutaneous mast cell tumours in Labrador retrievers. Br J Nutr (2011) 0.90
Hematologic, serum biochemical, and cortisol changes associated with anticipation of exercise and short duration high-intensity exercise in sled dogs. Vet Clin Pathol (2009) 0.87
D-amino acid based protein arginine deiminase inhibitors: Synthesis, pharmacokinetics, and in cellulo efficacy. ACS Med Chem Lett (2012) 0.86
Use of pedometers to measure the relationship of dog walking to body condition score in obese and non-obese dogs. Br J Nutr (2011) 0.86
Hepatic copper concentrations in Labrador Retrievers with and without chronic hepatitis: 72 cases (1980-2010). J Am Vet Med Assoc (2013) 0.85
Dysregulation of PAD4-mediated citrullination of nuclear GSK3β activates TGF-β signaling and induces epithelial-to-mesenchymal transition in breast cancer cells. Proc Natl Acad Sci U S A (2013) 0.85
TACC3 expression and localization in the murine egg and ovary. Mol Reprod Dev (2002) 0.83
The effects of weight loss on adipokines and markers of inflammation in dogs. Br J Nutr (2011) 0.82
Peptidylarginine deiminase (PAD) is a mouse cortical granule protein that plays a role in preimplantation embryonic development. Reprod Biol Endocrinol (2005) 0.80
A novel role for protein arginine deiminase 4 in pluripotency: the emerging role of citrullinated histone H1 in cellular programming. Bioessays (2014) 0.80
Evaluation of calcium, phosphorus, and selected trace mineral status in commercially available dry foods formulated for dogs. J Am Vet Med Assoc (2013) 0.78
Antibodies to two ZP3 B cell epitopes affect zona pellucida assembly. J Reprod Immunol (2008) 0.77
Assessment of canine autologous platelet-rich plasma produced with a commercial centrifugation and platelet recovery kit. Vet Comp Orthop Traumatol (2015) 0.76
Transient hyperlipidemia in a litter of kittens. J Vet Emerg Crit Care (San Antonio) (2012) 0.75
Evaluation of dietary energy intake and physical activity in dogs undergoing a controlled weight-loss program. J Am Vet Med Assoc (2012) 0.75
Cloning and antibody recognition analysis of the canine 5-lipoxygenase gene. Vet Immunol Immunopathol (2011) 0.75