|
1
|
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction.
|
Neuron
|
2003
|
14.03
|
|
2
|
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.
|
Neurobiol Aging
|
2003
|
3.83
|
|
3
|
Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology.
|
J Biol Chem
|
2005
|
2.56
|
|
4
|
Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles.
|
J Biol Chem
|
2006
|
2.33
|
|
5
|
Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice.
|
J Neurosci
|
2006
|
2.32
|
|
6
|
Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability.
|
J Neurosci
|
2004
|
1.92
|
|
7
|
A dynamic relationship between intracellular and extracellular pools of Abeta.
|
Am J Pathol
|
2006
|
1.66
|
|
8
|
Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease.
|
Proc Natl Acad Sci U S A
|
2005
|
1.51
|
|
9
|
Blocking Abeta42 accumulation delays the onset and progression of tau pathology via the C terminus of heat shock protein70-interacting protein: a mechanistic link between Abeta and tau pathology.
|
J Neurosci
|
2008
|
1.49
|
|
10
|
Methylene blue reduces aβ levels and rescues early cognitive deficit by increasing proteasome activity.
|
Brain Pathol
|
2011
|
1.46
|
|
11
|
Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling.
|
Aging Cell
|
2012
|
1.43
|
|
12
|
Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice.
|
Neurobiol Dis
|
2007
|
1.30
|
|
13
|
Genetically augmenting tau levels does not modulate the onset or progression of Abeta pathology in transgenic mice.
|
J Neurochem
|
2007
|
1.22
|
|
14
|
Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models.
|
Ann N Y Acad Sci
|
2007
|
1.13
|
|
15
|
Genetically altering Abeta distribution from the brain to the vasculature ameliorates tau pathology.
|
Brain Pathol
|
2008
|
0.96
|
|
16
|
Genetically augmenting Abeta42 levels in skeletal muscle exacerbates inclusion body myositis-like pathology and motor deficits in transgenic mice.
|
Am J Pathol
|
2006
|
0.93
|
|
17
|
Loss of muscarinic M1 receptor exacerbates Alzheimer's disease-like pathology and cognitive decline.
|
Am J Pathol
|
2011
|
0.93
|
|
18
|
Amyloid beta and the longest-lived rodent: the naked mole-rat as a model for natural protection from Alzheimer's disease.
|
Neurobiol Aging
|
2013
|
0.89
|
|
19
|
Oxidative damage and amyloid-β metabolism in brain regions of the longest-lived rodents.
|
J Neurosci Res
|
2013
|
0.86
|