Published in Science on February 11, 2005
Mode of action of Bacillus thuringiensis Cry and Cyt toxins and their potential for insect control. Toxicon (2006) 3.27
Role of receptors in Bacillus thuringiensis crystal toxin activity. Microbiol Mol Biol Rev (2007) 2.74
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Bacillus thuringiensis: A story of a successful bioinsecticide. Insect Biochem Mol Biol (2011) 2.43
Phytotoxicity and innate immune responses induced by Nep1-like proteins. Plant Cell (2006) 1.88
Bacillus thuringiensis Cry1Ca-resistant Spodoptera exigua lacks expression of one of four Aminopeptidase N genes. BMC Genomics (2005) 1.37
Domain II loop 3 of Bacillus thuringiensis Cry1Ab toxin is involved in a "ping pong" binding mechanism with Manduca sexta aminopeptidase-N and cadherin receptors. J Biol Chem (2009) 1.32
A purified Bacillus thuringiensis crystal protein with therapeutic activity against the hookworm parasite Ancylostoma ceylanicum. Proc Natl Acad Sci U S A (2006) 1.27
Synergism of Bacillus thuringiensis toxins by a fragment of a toxin-binding cadherin. Proc Natl Acad Sci U S A (2007) 1.25
The role of the inflammasome in cellular responses to toxins and bacterial effectors. Semin Immunopathol (2007) 1.25
Anopheles gambiae cadherin AgCad1 binds the Cry4Ba toxin of Bacillus thuringiensis israelensis and a fragment of AgCad1 synergizes toxicity. Biochemistry (2008) 1.25
Biosynthesis of truncated N-linked oligosaccharides results from non-orthologous hexosaminidase-mediated mechanisms in nematodes, plants, and insects. J Biol Chem (2007) 1.24
Caenorhabditis elegans N-glycan core beta-galactoside confers sensitivity towards nematotoxic fungal galectin CGL2. PLoS Pathog (2010) 1.23
Apicobasal domain identities of expanding tubular membranes depend on glycosphingolipid biosynthesis. Nat Cell Biol (2011) 1.16
Identification of a Bacillus thuringiensis Cry11Ba toxin-binding aminopeptidase from the mosquito, Anopheles quadrimaculatus. BMC Biochem (2006) 1.15
Glycomic studies of Drosophila melanogaster embryos. Glycoconj J (2006) 1.05
Discovery of a highly synergistic anthelmintic combination that shows mutual hypersusceptibility. Proc Natl Acad Sci U S A (2010) 1.04
Constitutive activation of the midgut response to Bacillus thuringiensis in Bt-resistant Spodoptera exigua. PLoS One (2010) 1.03
Bacillus thuringiensis Cry5B protein is highly efficacious as a single-dose therapy against an intestinal roundworm infection in mice. PLoS Negl Trop Dis (2010) 1.02
Notch ligand activity is modulated by glycosphingolipid membrane composition in Drosophila melanogaster. J Cell Biol (2010) 0.96
Effects of Bacillus thuringiensis delta-endotoxins on the pea aphid (Acyrthosiphon pisum). Appl Environ Microbiol (2009) 0.95
New positive regulators of lin-12 activity in Caenorhabditis elegans include the BRE-5/Brainiac glycosphingolipid biosynthesis enzyme. Genetics (2005) 0.94
P-type ATPase TAT-2 negatively regulates monomethyl branched-chain fatty acid mediated function in post-embryonic growth and development in C. elegans. PLoS Genet (2009) 0.94
A Caenorhabditis elegans glycolipid-binding galectin functions in host defense against bacterial infection. J Biol Chem (2009) 0.93
Nematotoxicity of Marasmius oreades agglutinin (MOA) depends on glycolipid binding and cysteine protease activity. J Biol Chem (2011) 0.93
Expression of ceramide glucosyltransferases, which are essential for glycosphingolipid synthesis, is only required in a small subset of C. elegans cells. J Cell Sci (2009) 0.93
Computational Modeling Deduced Three Dimensional Structure of Cry1Ab16 Toxin from Bacillus thuringiensis AC11. Indian J Microbiol (2011) 0.93
Structure and glycolipid binding properties of the nematicidal protein Cry5B. Biochemistry (2012) 0.92
Risk assessment of toxins derived from Bacillus thuringiensis-synergism, efficacy, and selectivity. Environ Sci Pollut Res Int (2009) 0.92
Protist-type lysozymes of the nematode Caenorhabditis elegans contribute to resistance against pathogenic Bacillus thuringiensis. PLoS One (2011) 0.92
Multiplexing ligand-receptor binding measurements by chemically patterning microfluidic channels. Anal Chem (2008) 0.92
Membrane interaction of Pasteurella multocida toxin involves sphingomyelin. FEBS J (2011) 0.92
A novel aminopeptidase in the fat body of the moth Achaea janata as a receptor for Bacillus thuringiensis Cry toxins and its comparison with midgut aminopeptidase. Biochem J (2007) 0.90
All domains of Cry1A toxins insert into insect brush border membranes. J Biol Chem (2008) 0.90
Multiple receptors as targets of Cry toxins in mosquitoes. J Agric Food Chem (2011) 0.90
Methylated glycans as conserved targets of animal and fungal innate defense. Proc Natl Acad Sci U S A (2014) 0.88
Bacterial pore-forming proteins as anthelmintics. Invert Neurosci (2012) 0.87
The pore-forming protein Cry5B elicits the pathogenicity of Bacillus sp. against Caenorhabditis elegans. PLoS One (2011) 0.87
Western corn rootworm (Diabrotica virgifera virgifera) transcriptome assembly and genomic analysis of population structure. BMC Genomics (2014) 0.87
The food and environmental safety of Bt crops. Front Plant Sci (2015) 0.86
Synergistic activity between Bacillus thuringiensis Cry6Aa and Cry55Aa toxins against Meloidogyne incognita. Microb Biotechnol (2011) 0.86
The theoretical 3D structure of Bacillus thuringiensis Cry5Ba. J Mol Model (2008) 0.86
Distinct contributions of beta 4GalNAcTA and beta 4GalNAcTB to Drosophila glycosphingolipid biosynthesis. Glycoconj J (2007) 0.85
UDP-galactopyranose mutase in nematodes. Biochemistry (2013) 0.84
Bisecting Galactose as a Feature of N-Glycans of Wild-type and Mutant Caenorhabditis elegans. Mol Cell Proteomics (2015) 0.84
Bacillus thuringiensis-derived Cry5B has potent anthelmintic activity against Ascaris suum. PLoS Negl Trop Dis (2013) 0.84
Bacillus thuringiensis DB27 produces two novel protoxins, Cry21Fa1 and Cry21Ha1, which act synergistically against nematodes. Appl Environ Microbiol (2014) 0.82
Functional interpretation of a non-gut hemocoelic tissue aminopeptidase N (APN) in a lepidopteran insect pest Achaea janata. PLoS One (2013) 0.82
Gene expression patterns and sequence polymorphisms associated with mosquito resistance to Bacillus thuringiensis israelensis toxins. BMC Genomics (2014) 0.82
Mechanistic and single-dose in vivo therapeutic studies of Cry5B anthelmintic action against hookworms. PLoS Negl Trop Dis (2012) 0.81
Interaction of Bacillus thuringiensis vegetative insecticidal protein with ribosomal S2 protein triggers larvicidal activity in Spodoptera frugiperda. Appl Environ Microbiol (2010) 0.81
Bacillus thuringiensis Crystal Protein Cry6Aa Triggers Caenorhabditis elegans Necrosis Pathway Mediated by Aspartic Protease (ASP-1). PLoS Pathog (2016) 0.81
Intraspecific epitopic variation in a carbohydrate antigen exposed on the surface of Trichostrongylus colubriformis infective L3 larvae. PLoS Pathog (2009) 0.80
Toxicological evaluation of proteins introduced into food crops. Crit Rev Toxicol (2013) 0.79
Caenorhabditis elegans galectins LEC-6 and LEC-10 interact with similar glycoconjugates in the intestine. J Biol Chem (2010) 0.79
New insight to structure-function relationship of GalNAc mediated primary interaction between insecticidal Cry1Ac toxin and HaALP receptor of Helicoverpa armigera. PLoS One (2013) 0.79
Bacillus subtilis strain engineered for treatment of soil-transmitted helminth diseases. Appl Environ Microbiol (2013) 0.79
Identification of distinct Bacillus thuringiensis 4A4 nematicidal factors using the model nematodes Pristionchus pacificus and Caenorhabditis elegans. Toxins (Basel) (2014) 0.78
Structural studies on the neutral glycosphingolipids of Manduca sexta. Bioorg Chem (2007) 0.78
Distribution and Metabolism of Bt-Cry1Ac Toxin in Tissues and Organs of the Cotton Bollworm, Helicoverpa armigera. Toxins (Basel) (2016) 0.78
Binding of Cyt1Aa and Cry11Aa toxins of Bacillus thuringiensis serovar israelensis to brush border membrane vesicles of Tipula paludosa (Diptera: Nematocera) and subsequent pore formation. Appl Environ Microbiol (2007) 0.77
Nematicidal spore-forming Bacilli share similar virulence factors and mechanisms. Sci Rep (2016) 0.77
The Natural Biotic Environment of Caenorhabditis elegans. Genetics (2017) 0.77
The PCome of Ascaris suum as a model system for intestinal nematodes: identification of phosphorylcholine-substituted proteins and first characterization of the PC-epitope structures. Parasitol Res (2016) 0.76
Effects of the Bacillus thuringiensis toxin Cry1Ab on membrane currents of isolated cells of the ruminal epithelium. J Membr Biol (2007) 0.76
Differential proteomic analysis of Trichoplusia ni cells after continuous selection with activated Cry1Ac toxin. Cytotechnology (2012) 0.75
A Novel Fucose-binding Lectin from Photorhabdus luminescens (PLL) with an Unusual Heptabladed β-Propeller Tetrameric Structure. J Biol Chem (2016) 0.75
Clozapine Modulates Glucosylceramide, Clears Aggregated Proteins, and Enhances ATG8/LC3 in Caenorhabditis elegans. Neuropsychopharmacology (2016) 0.75
Pre-feeding of a glycolipid binding protein LEC-8 from Caenorhabditis elegans revealed enhanced tolerance to Cry1Ac toxin in Helicoverpa armigera. Results Immunol (2012) 0.75
Involvement of Vitamin B6 Biosynthesis Pathways in the Insecticidal Activity of Photorhabdus luminescens. Appl Environ Microbiol (2016) 0.75
Lipid and Carbohydrate Metabolism in Caenorhabditis elegans. Genetics (2017) 0.75
Two novel dissimilar crystal proteins, Cry5Ca1 and Cry5Da1, synergistically act against Meloidogyne incognita and delay Cry5Ba-based nematode resistance. Appl Environ Microbiol (2017) 0.75
N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli. Science (2002) 4.04
GlycoWorkbench: a tool for the computer-assisted annotation of mass spectra of glycans. J Proteome Res (2008) 3.85
Interactions between macromolecules and ions: The Hofmeister series. Curr Opin Chem Biol (2006) 3.25
Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins. Proc Natl Acad Sci U S A (2004) 2.93
Comparison of the methods for profiling glycoprotein glycans--HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study. Glycobiology (2007) 2.71
Engineering N-linked protein glycosylation with diverse O antigen lipopolysaccharide structures in Escherichia coli. Proc Natl Acad Sci U S A (2005) 2.66
A sensitive, versatile microfluidic assay for bacterial chemotaxis. Proc Natl Acad Sci U S A (2003) 2.49
Sulfated fucans, fresh perspectives: structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide. Glycobiology (2003) 2.37
Postanalytical external quality assessment of urine albumin in primary health care: an international survey. Clin Chem (2008) 2.27
Single ion-channel recordings using glass nanopore membranes. J Am Chem Soc (2007) 2.22
Activation of the unfolded protein response is required for defenses against bacterial pore-forming toxin in vivo. PLoS Pathog (2008) 2.16
Functional analysis of the Campylobacter jejuni N-linked protein glycosylation pathway. Mol Microbiol (2005) 2.16
Comparative efficacy of neutralizing antibodies elicited by recombinant hemagglutinin proteins from avian H5N1 influenza virus. J Virol (2008) 2.14
Bacillus thuringiensis crystal proteins that target nematodes. Proc Natl Acad Sci U S A (2003) 2.08
Human sperm binding is mediated by the sialyl-Lewis(x) oligosaccharide on the zona pellucida. Science (2011) 2.02
Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium. FEBS Lett (2005) 1.96
Role of pore-forming toxins in bacterial infectious diseases. Microbiol Mol Biol Rev (2013) 1.91
Haloferax volcanii AglB and AglD are involved in N-glycosylation of the S-layer glycoprotein and proper assembly of the surface layer. J Mol Biol (2007) 1.90
Glycomic profiling of cells and tissues by mass spectrometry: fingerprinting and sequencing methodologies. Methods Enzymol (2006) 1.82
His-384 allotypic variant of factor H associated with age-related macular degeneration has different heparin binding properties from the non-disease-associated form. J Biol Chem (2006) 1.79
Mass spectrometry in the analysis of N-linked and O-linked glycans. Curr Opin Struct Biol (2009) 1.77
Automatic annotation of matrix-assisted laser desorption/ionization N-glycan spectra. Proteomics (2005) 1.76
Characterization of a Cry1Ac-receptor alkaline phosphatase in susceptible and resistant Heliothis virescens larvae. Eur J Biochem (2004) 1.75
Altered Glycosylation of 63- and 68-kilodalton microvillar proteins in Heliothis virescens correlates with reduced Cry1 toxin binding, decreased pore formation, and increased resistance to Bacillus thuringiensis Cry1 toxins. Appl Environ Microbiol (2002) 1.73
Specific ion effects on the water solubility of macromolecules: PNIPAM and the Hofmeister series. J Am Chem Soc (2005) 1.73
Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome. Nat Chem Biol (2012) 1.70
Eosinophils in the zebrafish: prospective isolation, characterization, and eosinophilia induction by helminth determinants. Blood (2010) 1.69
Characterization of the oligosaccharides associated with the human ovarian tumor marker CA125. J Biol Chem (2003) 1.63
Glycomic analysis of human respiratory tract tissues and correlation with influenza virus infection. PLoS Pathog (2013) 1.62
The GlycanBuilder: a fast, intuitive and flexible software tool for building and displaying glycan structures. Source Code Biol Med (2007) 1.61
Characterization of the structural features and interactions of sclerostin: molecular insight into a key regulator of Wnt-mediated bone formation. J Biol Chem (2009) 1.60
Glycomics profiling of Chinese hamster ovary cell glycosylation mutants reveals N-glycans of a novel size and complexity. J Biol Chem (2009) 1.58
Investigating the hydrogen-bonding model of urea denaturation. J Am Chem Soc (2009) 1.57
The GlycanBuilder and GlycoWorkbench glycoinformatics tools: updates and new developments. Biol Chem (2012) 1.55
Mass spectrometric analysis of N- and O-glycosylation of tissues and cells. Curr Opin Struct Biol (2006) 1.53
Glycan analysis and influenza A virus infection of primary swine respiratory epithelial cells: the importance of NeuAc{alpha}2-6 glycans. J Biol Chem (2010) 1.53
VEGF165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase. J Biol Chem (2005) 1.53
GM1 clustering inhibits cholera toxin binding in supported phospholipid membranes. J Am Chem Soc (2007) 1.52
Unique modifications with phosphocholine and phosphoethanolamine define alternate antigenic forms of Neisseria gonorrhoeae type IV pili. Proc Natl Acad Sci U S A (2004) 1.52
Global functional analyses of cellular responses to pore-forming toxins. PLoS Pathog (2011) 1.52
Chemistry of Hofmeister anions and osmolytes. Annu Rev Phys Chem (2010) 1.50
A focused microarray approach to functional glycomics: transcriptional regulation of the glycome. Glycobiology (2005) 1.49
Transglutaminase-mediated semen coagulation controls sperm storage in the malaria mosquito. PLoS Biol (2009) 1.49
Characterization of the O antigen gene cluster and structural analysis of the O antigen of Francisella tularensis subsp. tularensis. J Med Microbiol (2003) 1.48
Deletion of Cg-emb in corynebacterianeae leads to a novel truncated cell wall arabinogalactan, whereas inactivation of Cg-ubiA results in an arabinan-deficient mutant with a cell wall galactan core. J Biol Chem (2005) 1.45
AglF, aglG and aglI, novel members of a gene island involved in the N-glycosylation of the Haloferax volcanii S-layer glycoprotein. Mol Microbiol (2008) 1.45
Bone morphogenetic protein and growth differentiation factor cytokine families and their protein antagonists. Biochem J (2010) 1.45
Comparison of methods for profiling O-glycosylation: Human Proteome Organisation Human Disease Glycomics/Proteome Initiative multi-institutional study of IgA1. Mol Cell Proteomics (2009) 1.45
Chemotactic separation of enzymes. ACS Nano (2014) 1.44
The anaphase-promoting complex and separin are required for embryonic anterior-posterior axis formation. Dev Cell (2002) 1.43
Neoglycolipid probes prepared via oxime ligation for microarray analysis of oligosaccharide-protein interactions. Chem Biol (2007) 1.42
Identification of AglE, a second glycosyltransferase involved in N glycosylation of the Haloferax volcanii S-layer glycoprotein. J Bacteriol (2008) 1.41
AglP is a S-adenosyl-L-methionine-dependent methyltransferase that participates in the N-glycosylation pathway of Haloferax volcanii. Mol Microbiol (2010) 1.41
Resistance to a bacterial toxin is mediated by removal of a conserved glycosylation pathway required for toxin-host interactions. J Biol Chem (2003) 1.41
The Vroman effect: a molecular level description of fibrinogen displacement. J Am Chem Soc (2003) 1.41
Identification of novel Bacillus thuringiensis Cry1Ac binding proteins in Manduca sexta midgut through proteomic analysis. Insect Biochem Mol Biol (2003) 1.40
AglJ adds the first sugar of the N-linked pentasaccharide decorating the Haloferax volcanii S-layer glycoprotein. J Bacteriol (2010) 1.38
Creating fluid and air-stable solid supported lipid bilayers. J Am Chem Soc (2004) 1.36
Design and characterization of immobilized enzymes in microfluidic systems. Anal Chem (2002) 1.35
Many roads to resistance: how invertebrates adapt to Bt toxins. Bioessays (2005) 1.35
RAB-5- and RAB-11-dependent vesicle-trafficking pathways are required for plasma membrane repair after attack by bacterial pore-forming toxin. Cell Host Microbe (2011) 1.35
Hypoxia and the hypoxic response pathway protect against pore-forming toxins in C. elegans. PLoS Pathog (2009) 1.35
Dendritic cell maturation results in pronounced changes in glycan expression affecting recognition by siglecs and galectins. J Immunol (2007) 1.34
The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting mass-spectrometry-based glycoanalytic data. Mol Cell Proteomics (2013) 1.34
Activation of murine CD4+ and CD8+ T lymphocytes leads to dramatic remodeling of N-linked glycans. J Immunol (2006) 1.34
N-glycosylation in Archaea: on the coordinated actions of Haloferax volcanii AglF and AglM. Mol Microbiol (2010) 1.34
Glycosylation status of haptoglobin in sera of patients with prostate cancer vs. benign prostate disease or normal subjects. Int J Cancer (2008) 1.33
Histo-blood group antigens act as attachment factors of rabbit hemorrhagic disease virus infection in a virus strain-dependent manner. PLoS Pathog (2011) 1.31
Characterization of a putative alpha-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis. Biochem J (2002) 1.31
Bt-R1a extracellular cadherin repeat 12 mediates Bacillus thuringiensis Cry1Ab binding and cytotoxicity. J Biol Chem (2004) 1.30
A generic mechanism in Neisseria meningitidis for enhanced resistance against bactericidal antibodies. J Exp Med (2008) 1.30
Glycosyltransferase function in core 2-type protein O glycosylation. Mol Cell Biol (2009) 1.30
A microfluidic device with a linear temperature gradient for parallel and combinatorial measurements. J Am Chem Soc (2002) 1.30
Potent suppression of natural killer cell response mediated by the ovarian tumor marker CA125. Gynecol Oncol (2005) 1.30
Assays for toxicity studies in C. elegans with Bt crystal proteins. Methods Mol Biol (2006) 1.29
Sialic acid capping of CD8beta core 1-O-glycans controls thymocyte-major histocompatibility complex class I interaction. J Biol Chem (2002) 1.29
Structural characterisation of neutrophil glycans by ultra sensitive mass spectrometric glycomics methodology. Glycoconj J (2009) 1.28