Gary Fiskum

Author PubWeight™ 89.91‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Generation of reactive oxygen species by the mitochondrial electron transport chain. J Neurochem 2002 3.61
2 Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species. J Neurosci 2004 2.57
3 Regulation of brain mitochondrial H2O2 production by membrane potential and NAD(P)H redox state. J Neurochem 2003 2.46
4 Hyperoxic resuscitation improves survival but worsens neurologic outcome in a rat polytrauma model of traumatic brain injury plus hemorrhagic shock. J Trauma Acute Care Surg 2015 1.97
5 Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury. Cell Calcium 2004 1.86
6 Mitochondrial mechanisms of neural cell apoptosis. J Neurochem 2004 1.65
7 Diffusion kurtosis as an in vivo imaging marker for reactive astrogliosis in traumatic brain injury. Neuroimage 2011 1.45
8 Hyperoxic reperfusion after global ischemia decreases hippocampal energy metabolism. Stroke 2007 1.37
9 Normoxic resuscitation after cardiac arrest protects against hippocampal oxidative stress, metabolic dysfunction, and neuronal death. J Cereb Blood Flow Metab 2006 1.36
10 Novel mitochondrial targets for neuroprotection. J Cereb Blood Flow Metab 2012 1.35
11 Pyruvate dehydrogenase complex: metabolic link to ischemic brain injury and target of oxidative stress. J Neurosci Res 2004 1.32
12 Mitochondrial mechanisms of cell death and neuroprotection in pediatric ischemic and traumatic brain injury. Exp Neurol 2009 1.31
13 Oximetry-guided reoxygenation improves neurological outcome after experimental cardiac arrest. Stroke 2006 1.31
14 Dietary omega-3 fatty acids alter cardiac mitochondrial phospholipid composition and delay Ca2+-induced permeability transition. J Mol Cell Cardiol 2009 1.28
15 Regulation of hydrogen peroxide production by brain mitochondria by calcium and Bax. J Neurochem 2002 1.26
16 Isolation of mitochondria with high respiratory control from primary cultures of neurons and astrocytes using nitrogen cavitation. J Neurosci Methods 2005 1.24
17 Cyclosporin A-insensitive permeability transition in brain mitochondria: inhibition by 2-aminoethoxydiphenyl borate. J Biol Chem 2003 1.18
18 Physiologic progesterone reduces mitochondrial dysfunction and hippocampal cell loss after traumatic brain injury in female rats. Exp Neurol 2005 1.16
19 Upregulation of the Fas receptor death-inducing signaling complex after traumatic brain injury in mice and humans. J Neurosci 2002 1.15
20 Postischemic hyperoxia reduces hippocampal pyruvate dehydrogenase activity. Free Radic Biol Med 2006 1.15
21 Dietary supplementation with docosahexaenoic acid, but not eicosapentaenoic acid, dramatically alters cardiac mitochondrial phospholipid fatty acid composition and prevents permeability transition. Biochim Biophys Acta 2010 1.14
22 Mechanisms of impaired mitochondrial energy metabolism in acute and chronic neurodegenerative disorders. J Neurosci Res 2007 1.14
23 GABAergic mechanism of propofol toxicity in immature neurons. J Neurosurg Anesthesiol 2008 1.13
24 Early microstructural and metabolic changes following controlled cortical impact injury in rat: a magnetic resonance imaging and spectroscopy study. J Neurotrauma 2011 1.12
25 Nrf2 activators provide neuroprotection against 6-hydroxydopamine toxicity in rat organotypic nigrostriatal cocultures. J Neurosci Res 2009 1.11
26 Sulforaphane protects astrocytes against oxidative stress and delayed death caused by oxygen and glucose deprivation. Glia 2009 1.10
27 Inhibition of Bax-induced cytochrome c release from neural cell and brain mitochondria by dibucaine and propranolol. J Neurosci 2003 1.09
28 Mechanisms of ischemic neuroprotection by acetyl-L-carnitine. Ann N Y Acad Sci 2005 1.07
29 Hyperbaric oxygen reduces neuronal death and improves neurological outcome after canine cardiac arrest. Stroke 2003 1.07
30 Mitochondrial dysfunction early after traumatic brain injury in immature rats. J Neurochem 2007 1.06
31 Astrocyte mitochondrial mechanisms of ischemic brain injury and neuroprotection. Neurochem Res 2004 1.06
32 Neuroprotection by acetyl-L-carnitine after traumatic injury to the immature rat brain. Dev Neurosci 2011 1.06
33 Metabolism of acetyl-L-carnitine for energy and neurotransmitter synthesis in the immature rat brain. J Neurochem 2010 1.05
34 Cyclosporin A increases mitochondrial calcium uptake capacity in cortical astrocytes but not cerebellar granule neurons. J Bioenerg Biomembr 2006 1.05
35 Hyperoxic reperfusion after global cerebral ischemia promotes inflammation and long-term hippocampal neuronal death. J Neurotrauma 2010 1.02
36 Effect of Bcl-2 overexpression on mitochondrial structure and function. J Biol Chem 2002 1.02
37 The potential role of mitochondria in pediatric traumatic brain injury. Dev Neurosci 2006 1.02
38 Bcl-2 family proteins regulate mitochondrial reactive oxygen production and protect against oxidative stress. Free Radic Biol Med 2004 1.01
39 Redox mechanisms of cytoprotection by Bcl-2. Antioxid Redox Signal 2005 1.01
40 The role of tetrahydrobiopterin in the regulation of neuronal nitric-oxide synthase-generated superoxide. J Biol Chem 2002 1.00
41 Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation. Exp Neurol 2004 0.98
42 Heterogeneity of the calcium-induced permeability transition in isolated non-synaptic brain mitochondria. J Neurochem 2002 0.98
43 Delayed cerebral oxidative glucose metabolism after traumatic brain injury in young rats. J Neurochem 2009 0.98
44 Influence of aging on membrane permeability transition in brain mitochondria. J Bioenerg Biomembr 2011 0.96
45 Calcium-induced precipitate formation in brain mitochondria: composition, calcium capacity, and retention. J Neurochem 2007 0.96
46 Sulforaphane inhibits mitochondrial permeability transition and oxidative stress. Free Radic Biol Med 2011 0.96
47 Quantitative imaging of mitochondrial and cytosolic free zinc levels in an in vitro model of ischemia/reperfusion. J Bioenerg Biomembr 2012 0.95
48 Neuroprotective effects of hyperbaric oxygen treatment in experimental focal cerebral ischemia are associated with reduced brain leukocyte myeloperoxidase activity. Brain Res 2003 0.95
49 Early and sustained alterations in cerebral metabolism after traumatic brain injury in immature rats. J Neurotrauma 2008 0.95
50 Hyperoxia promotes astrocyte cell death after oxygen and glucose deprivation. Glia 2008 0.92
51 Inhibition of glutamate-induced delayed calcium deregulation by 2-APB and La3+ in cultured cortical neurones. J Neurochem 2004 0.92
52 Methoxychlor inhibits brain mitochondrial respiration and increases hydrogen peroxide production and CREB phosphorylation. Toxicol Sci 2005 0.91
53 Neuron-specific conditional expression of a mitochondrially targeted fluorescent protein in mice. J Neurosci 2006 0.91
54 Brain mitochondria from rats treated with sulforaphane are resistant to redox-regulated permeability transition. J Bioenerg Biomembr 2010 0.91
55 Postnatal developmental regulation of Bcl-2 family proteins in brain mitochondria. J Neurosci Res 2008 0.91
56 Sulforaphane protects immature hippocampal neurons against death caused by exposure to hemin or to oxygen and glucose deprivation. J Neurosci Res 2010 0.90
57 Effects of FK506 and cyclosporin a on calcium ionophore-induced mitochondrial depolarization and cytosolic calcium in astrocytes and neurons. J Neurosci Res 2011 0.89
58 Cyclophilin D is expressed predominantly in mitochondria of gamma-aminobutyric acidergic interneurons. J Neurosci Res 2009 0.89
59 A fluorescence-based technique for screening compounds that protect against damage to brain mitochondria. Brain Res Brain Res Protoc 2004 0.87
60 Neuroprotection through stimulation of mitochondrial antioxidant protein expression. J Alzheimers Dis 2010 0.86
61 Mitochondrial response to calcium in the developing brain. Brain Res Dev Brain Res 2004 0.85
62 Regulation of mitochondrial gene expression by energy demand in neural cells. J Neurochem 2005 0.85
63 Expression of cellular FLICE inhibitory proteins (cFLIP) in normal and traumatic murine and human cerebral cortex. J Cereb Blood Flow Metab 2005 0.85
64 TAT-mediated endocytotic delivery of the loop deletion Bcl-2 protein protects neurons against cell death. J Neurochem 2005 0.83
65 Delayed therapy of experimental global cerebral ischemia with acetyl-L-carnitine in dogs. Neurosci Lett 2005 0.83
66 Anoxia-induced changes in pyridine nucleotide redox state in cortical neurons and astrocytes. Neurochem Res 2006 0.83
67 Inhibition of mitochondrial neural cell death pathways by protein transduction of Bcl-2 family proteins. J Bioenerg Biomembr 2005 0.82
68 Normoxic ventilatory resuscitation following controlled cortical impact reduces peroxynitrite-mediated protein nitration in the hippocampus. J Neurosurg 2008 0.82
69 Cellular alterations in human traumatic brain injury: changes in mitochondrial morphology reflect regional levels of injury severity. J Neurotrauma 2013 0.82
70 Effects of the organochlorine pesticide methoxychlor on dopamine metabolites and transporters in the mouse brain. Neurotoxicology 2009 0.81
71 Visualization and quantification of NAD(H) in brain sections by a novel histo-enzymatic nitrotetrazolium blue staining technique. Brain Res 2009 0.81
72 Cerebral glucose metabolism in an immature rat model of pediatric traumatic brain injury. J Neurotrauma 2013 0.81
73 Diacylglycerols activate mitochondrial cationic channel(s) and release sequestered Ca(2+). J Bioenerg Biomembr 2005 0.80
74 Magnesium sulfate protects against the bioenergetic consequences of chronic glutamate receptor stimulation. PLoS One 2013 0.79
75 Oxygen: could there be too much of a good thing? Hosp Med 2005 0.78
76 Bilobalide, a component of the Ginkgo biloba extract (EGb 761), protects against neuronal death in global brain ischemia and in glutamate-induced excitotoxicity. Cell Mol Biol (Noisy-le-grand) 2002 0.78
77 Augmentation of normal and glutamate-impaired neuronal respiratory capacity by exogenous alternative biofuels. Transl Stroke Res 2013 0.77
78 Hypotensive hemorrhage increases calcium uptake capacity and Bcl-XL content of liver mitochondria. Shock 2007 0.77
79 Calcium-dependent dephosphorylation of brain mitochondrial calcium/cAMP response element binding protein (CREB). J Neurochem 2005 0.77
80 Synthes Award for Resident Research on Brain and Craniofacial Injury: normoxic ventilatory resuscitation after controlled cortical impact reduces peroxynitrite-mediated protein nitration in the hippocampus. Clin Neurosurg 2005 0.76
81 Common threads in neurodegenerative disorders of aging. Alzheimers Dement 2006 0.76
82 The IFN-beta and retinoic acid-induced cell death regulator GRIM-19 is upregulated during focal cerebral ischemia. J Interferon Cytokine Res 2007 0.76
83 Permeability transition pore-dependent and PARP-mediated depletion of neuronal pyridine nucleotides during anoxia and glucose deprivation. J Bioenerg Biomembr 2014 0.75
84 Perinatal brain injury: the role of development in vulnerability. Anesthesiology 2003 0.75
85 Rat model of brain injury caused by under-vehicle blast-induced hyperacceleration. J Trauma Acute Care Surg 2014 0.75
86 Aeromedical evacuation-relevant hypobaria worsens axonal and neurologic injury in rats following underbody blast-induced hyperacceleration. J Trauma Acute Care Surg 2017 0.75