Kye Jung Shin

Author PubWeight™ 16.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Synthesis and biological evaluations of pyrazolo[3,4-d]pyrimidines as cyclin-dependent kinase 2 inhibitors. Eur J Med Chem 2003 0.95
2 Expression of liver X receptor correlates with intrahepatic inflammation and fibrosis in patients with nonalcoholic fatty liver disease. Dig Dis Sci 2014 0.91
3 An approach to enhance specificity against RNA targets using heteroconjugates of aminoglycosides and chloramphenicol (or linezolid). J Am Chem Soc 2004 0.87
4 Biomimetic asymmetric total synthesis of (-)-laurefucin via an organoselenium-mediated intramolecular hydroxyetherification. J Am Chem Soc 2008 0.86
5 Bis-styrylpyridine and bis-styrylbenzene derivatives as inhibitors for Abeta fibril formation. Bioorg Med Chem Lett 2006 0.85
6 IKKbeta inhibitors identification part II: ligand and structure-based virtual screening. Bioorg Med Chem 2010 0.85
7 A hybrid molecule that prohibits amyloid fibrils and alleviates neuronal toxicity induced by beta-amyloid (1-42). Biochem Biophys Res Commun 2005 0.80
8 IKKβ inhibitor identification: a multi-filter driven novel scaffold. BMC Bioinformatics 2010 0.80
9 Discovery of piperidinyl aminopyrimidine derivatives as IKK-2 inhibitors. Bioorg Med Chem Lett 2011 0.79
10 Glucuronidation of a sarpogrelate active metabolite is mediated by UDP-glucuronosyltransferases 1A4, 1A9, and 2B4. Drug Metab Dispos 2013 0.78
11 Small molecules that protect against β-amyloid-induced cytotoxicity by inhibiting aggregation of β-amyloid. Bioorg Med Chem 2012 0.78
12 3D QSAR pharmacophore model based on diverse IKKβ inhibitors. J Mol Model 2010 0.78
13 Ferulic acid and benzothiazole dimer derivatives with high binding affinity to beta-amyloid fibrils. Bioorg Med Chem Lett 2007 0.76
14 Synthesis and structure-activity relationships of tri-substituted thiazoles as RAGE antagonists for the treatment of Alzheimer's disease. Bioorg Med Chem Lett 2012 0.76
15 Synthesis and biological evaluation of novel 1 beta-methylcarbapenems with isothiazoloethenyl side chains. Bioorg Med Chem Lett 2003 0.76
16 2-Phenylbenzofuran derivatives alleviate mitochondrial damage via the inhibition of β-amyloid aggregation. Bioorg Med Chem Lett 2013 0.76
17 Synthesis and biological activity of novel 1beta-methylcarbapenems with oxyiminopyrrolidinylamide moiety. Bioorg Med Chem Lett 2003 0.76
18 Substrate-controlled asymmetric total synthesis and structure revision of (+)-itomanallene A. Angew Chem Int Ed Engl 2010 0.75
19 Induction of NQO1 and Neuroprotection by a Novel Compound KMS04014 in Parkinson's Disease Models. J Mol Neurosci 2015 0.75
20 Novel 1beta-methylcarbapenems with isoxazoloethenyl moieties containing carboxylic acid sodium salt. Bioorg Med Chem Lett 2005 0.75
21 Synthesis of heteroarylpiperazines and heteroarylbipiperidines with a restricted side chain and their affinities for 5-HT1A receptor. Arch Pharm (Weinheim) 2003 0.75
22 Synthesis and evaluation of alpha,alpha'-disubstituted phenylacetate derivatives for T-type calcium channel blockers. Bioorg Med Chem Lett 2008 0.75
23 Discovery of potent and selective rhodanine type IKKβ inhibitors by hit-to-lead strategy. Bioorg Med Chem Lett 2012 0.75
24 The relationship between glucuronide conjugate levels and hepatotoxicity after oral administration of valproic acid. Arch Pharm Res 2009 0.75
25 Synthesis and biological evaluation of 4-piperidinecarboxylate and 4-piperidinecyanide derivatives for T-type calcium channel blockers. Bioorg Med Chem Lett 2011 0.75
26 Inhibitory effect of pyridyloxy- or phenoxylphenoxyalkanate derivatives on rat lens aldose reductase and rat platelet aggregation. J Pharm Pharmacol 2004 0.75