1
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Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation.
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J Biol Chem
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2004
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3.35
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2
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Regulation of T cell development by the deubiquitinating enzyme CYLD.
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Nat Immunol
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2006
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2.73
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3
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Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation.
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J Biol Chem
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2004
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2.30
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4
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Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses.
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J Exp Med
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2007
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2.14
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5
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The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.
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Cancer Cell
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2010
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2.09
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6
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Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD.
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Dev Cell
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2007
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2.05
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7
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Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100.
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J Biol Chem
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2002
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1.90
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8
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Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production.
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Nat Immunol
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2009
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1.86
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9
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Negative regulation of JNK signaling by the tumor suppressor CYLD.
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J Biol Chem
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2004
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1.79
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10
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Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD.
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J Biol Chem
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2008
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1.78
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11
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IkappaB kinase is an essential component of the Tpl2 signaling pathway.
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Mol Cell Biol
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2004
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1.76
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12
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The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling.
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Nat Immunol
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2012
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1.68
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13
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Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation.
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Mol Cell Biol
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2005
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1.61
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14
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Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice.
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J Clin Invest
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2008
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1.53
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15
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The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity.
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Nat Immunol
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2011
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1.45
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16
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An atypical tumor necrosis factor (TNF) receptor-associated factor-binding motif of B cell-activating factor belonging to the TNF family (BAFF) receptor mediates induction of the noncanonical NF-kappaB signaling pathway.
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J Biol Chem
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2005
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1.37
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17
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The E3 ubiquitin ligase GRAIL regulates T cell tolerance and regulatory T cell function by mediating T cell receptor-CD3 degradation.
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Immunity
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2010
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1.31
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18
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Distinct signal codes generate dendritic cell functional plasticity.
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Sci Signal
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2010
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1.30
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19
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Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK.
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Blood
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2009
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1.29
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20
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Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase.
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J Biol Chem
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2006
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1.23
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21
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OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3.
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Nature
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2013
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1.21
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22
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The specificity of innate immune responses is enforced by repression of interferon response elements by NF-κB p50.
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Sci Signal
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2011
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1.18
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23
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TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage.
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Am J Physiol Cell Physiol
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2005
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1.16
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24
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CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation.
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Proc Natl Acad Sci U S A
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2014
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1.15
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25
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Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK.
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EMBO Rep
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2007
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1.12
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26
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beta-TrCP binding and processing of NF-kappaB2/p100 involve its phosphorylation at serines 866 and 870.
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Cell Signal
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2005
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1.09
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27
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Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation.
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Nat Med
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2013
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1.08
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28
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TSLP production by epithelial cells exposed to immunodeficiency virus triggers DC-mediated mucosal infection of CD4+ T cells.
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Proc Natl Acad Sci U S A
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2009
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1.07
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29
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Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells.
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Nat Immunol
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2012
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1.05
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30
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Peli: a family of signal-responsive E3 ubiquitin ligases mediating TLR signaling and T-cell tolerance.
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Cell Mol Immunol
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2012
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1.04
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31
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CD2AP/SHIP1 complex positively regulates plasmacytoid dendritic cell receptor signaling by inhibiting the E3 ubiquitin ligase Cbl.
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J Immunol
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2012
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1.03
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32
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Deubiquitinating enzyme CYLD regulates the peripheral development and naive phenotype maintenance of B cells.
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J Biol Chem
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2007
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1.01
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33
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Regulation of natural killer T-cell development by deubiquitinase CYLD.
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EMBO J
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2010
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1.01
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34
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NF-kappa B1 p105 regulates T cell homeostasis and prevents chronic inflammation.
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J Immunol
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2009
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1.00
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35
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Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter.
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Proc Natl Acad Sci U S A
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2010
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1.00
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36
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RKIP inhibits NF-kappaB in cancer cells by regulating upstream signaling components of the IkappaB kinase complex.
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FEBS Lett
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2009
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0.99
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37
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Noncanonical NF-kappaB regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development.
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Proc Natl Acad Sci U S A
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2011
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0.99
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38
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HTLV-2 Tax immortalizes human CD4+ memory T lymphocytes by oncogenic activation and dysregulation of autophagy.
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J Biol Chem
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2012
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0.98
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39
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Study of T-cell signaling by somatic cell mutagenesis and complementation cloning.
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J Immunol Methods
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2003
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0.97
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40
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Human T cell leukemia virus type I Tax activates CD40 gene expression via the NF-kappa B pathway.
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Virology
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2005
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0.95
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41
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Ubiquitin-specific protease 25 regulates TLR4-dependent innate immune responses through deubiquitination of the adaptor protein TRAF3.
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Sci Signal
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2013
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0.95
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42
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Regulation of NF-kappaB2/p100 processing by its nuclear shuttling.
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Oncogene
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2003
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0.95
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43
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TRAF3 regulates the effector function of regulatory T cells and humoral immune responses.
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J Exp Med
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2013
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0.93
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44
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Deregulated activation of oncoprotein kinase Tpl2/Cot in HTLV-I-transformed T cells.
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J Biol Chem
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2006
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0.89
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45
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Phosphorylation of NF-kappaB1/p105 by oncoprotein kinase Tpl2: implications for a novel mechanism of Tpl2 regulation.
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Biochim Biophys Acta
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2006
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0.86
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46
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TRIM28 mediates chromatin modifications at the TCRα enhancer and regulates the development of T and natural killer T cells.
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Proc Natl Acad Sci U S A
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2012
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0.86
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47
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CARMA1 regulation of regulatory T cell development involves modulation of interleukin-2 receptor signaling.
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J Biol Chem
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2010
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0.86
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48
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Deregulation of Tpl2 and NF-kappaB signaling and induction of macrophage apoptosis by the anti-depressant drug lithium.
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Cell Signal
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2008
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0.84
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49
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Regulation of antiviral innate immunity by deubiquitinase CYLD.
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Cell Mol Immunol
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2011
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0.83
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50
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S9, a 19 S proteasome subunit interacting with ubiquitinated NF-kappaB2/p100.
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J Biol Chem
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2002
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0.82
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51
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Regulation of hematopoiesis by the K63-specific ubiquitin-conjugating enzyme Ubc13.
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Proc Natl Acad Sci U S A
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2009
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0.81
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52
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A special issue on NF-κB signaling and function.
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Cell Res
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2011
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0.81
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53
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Activation of the transcription factor c-Maf in T cells is dependent on the CARMA1-IKKβ signaling cascade.
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Sci Signal
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2013
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0.79
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54
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The E3 ligase c-Cbl regulates dendritic cell activation.
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EMBO Rep
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2011
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0.78
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55
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Immune receptor signaling: from ubiquitination to NF-κB activation.
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Cell Mol Immunol
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2012
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0.75
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