Ronald G Duggleby

Author PubWeight™ 24.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Human sulfotransferases and their role in chemical metabolism. Toxicol Sci 2005 2.27
2 NMR analysis of covalent intermediates in thiamin diphosphate enzymes. Biochemistry 2003 1.48
3 Structure of a human carcinogen-converting enzyme, SULT1A1. Structural and kinetic implications of substrate inhibition. J Biol Chem 2002 1.42
4 Crystal structure of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors. J Mol Biol 2002 1.24
5 Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase. Proc Natl Acad Sci U S A 2006 1.21
6 A new approach to 'megaprimer' polymerase chain reaction mutagenesis without an intermediate gel purification step. BMC Biotechnol 2004 1.19
7 Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase. J Biol Chem 2002 1.16
8 Structure-activity relationships for a new family of sulfonylurea herbicides. J Comput Aided Mol Des 2005 1.13
9 Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase. Biochemistry 2005 1.12
10 The crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate. J Biol Chem 2003 1.08
11 The structure of human SULT1A1 crystallized with estradiol. An insight into active site plasticity and substrate inhibition with multi-ring substrates. J Biol Chem 2005 1.06
12 Active site mutations and substrate inhibition in human sulfotransferase 1A1 and 1A3. J Biol Chem 2004 1.05
13 Regulatory interactions in Arabidopsis thaliana acetohydroxyacid synthase. FEBS Lett 2002 0.99
14 Electron transfer in acetohydroxy acid synthase as a side reaction of catalysis. Implications for the reactivity and partitioning of the carbanion/enamine form of (alpha-hydroxyethyl)thiamin diphosphate in a "nonredox" flavoenzyme. Biochemistry 2004 0.98
15 The crystal structure of a bacterial class II ketol-acid reductoisomerase: domain conservation and evolution. Protein Sci 2005 0.93
16 Thiamin nutrition and catalysis-induced instability of thiamin diphosphate. Br J Nutr 2006 0.87
17 Mechanisms of acetohydroxyacid synthases. Curr Opin Chem Biol 2005 0.86
18 How an enzyme answers multiple-choice questions. Trends Biochem Sci 2005 0.86
19 Probing the mechanism of the bifunctional enzyme ketol-acid reductoisomerase by site-directed mutagenesis of the active site. FEBS J 2005 0.83
20 A CFTR chloride channel activator prevents HrpN(ea)-induced cell death in Arabidopsis thaliana suspension cells. Plant Physiol Biochem 2005 0.81
21 Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase. FEBS J 2009 0.80
22 Facile crystallization of Escherichia coli ketol-acid reductoisomerase. Acta Crystallogr D Biol Crystallogr 2004 0.78
23 Mutations in the regulatory subunit of yeast acetohydroxyacid synthase affect its activation by MgATP. Biochem J 2006 0.75
24 Biochemical characterization of two mutants of human pyruvate dehydrogenase, F205L and T231A of the E1alpha subunit. J Inherit Metab Dis 2003 0.75
25 Synthesis, crystal structure and herbicidal activity of mimics of intermediates of the KARI reaction. Pest Manag Sci 2005 0.75