Published in Annu Rev Physiol on January 01, 2005
Cep164, a novel centriole appendage protein required for primary cilium formation. J Cell Biol (2007) 3.88
Clinical and genetic aspects of primary ciliary dyskinesia/Kartagener syndrome. Genet Med (2009) 2.71
Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2+ and cAMP signaling. Gastroenterology (2006) 2.43
Direct recording and molecular identification of the calcium channel of primary cilia. Nature (2013) 2.27
Midbody and primary cilium of neural progenitors release extracellular membrane particles enriched in the stem cell marker prominin-1. J Cell Biol (2007) 2.19
Molecular characterization of centriole assembly in ciliated epithelial cells. J Cell Biol (2007) 2.13
FAPP2, cilium formation, and compartmentalization of the apical membrane in polarized Madin-Darby canine kidney (MDCK) cells. Proc Natl Acad Sci U S A (2006) 2.08
Ciliary polycystin-2 is a mechanosensitive calcium channel involved in nitric oxide signaling cascades. Circ Res (2009) 2.02
Human hepatic stem cell and maturational liver lineage biology. Hepatology (2011) 1.99
ATP release from non-excitable cells. Purinergic Signal (2009) 1.78
Forcing form and function: biomechanical regulation of tumor evolution. Trends Cell Biol (2010) 1.77
Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2+ signaling. Am J Physiol Renal Physiol (2006) 1.72
Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors. Am J Physiol Gastrointest Liver Physiol (2008) 1.56
Role of primary cilia in brain development and cancer. Curr Opin Neurobiol (2010) 1.49
Translocation of aquaporin-containing vesicles to the plasma membrane is facilitated by actomyosin relaxation. Biophys J (2007) 1.47
Diffusion of a soluble protein, photoactivatable GFP, through a sensory cilium. J Gen Physiol (2010) 1.47
Mutations in zebrafish leucine-rich repeat-containing six-like affect cilia motility and result in pronephric cysts, but have variable effects on left-right patterning. Development (2009) 1.31
Direct interactions of intraflagellar transport complex B proteins IFT88, IFT52, and IFT46. J Biol Chem (2010) 1.31
Cholangiocyte primary cilia in liver health and disease. Dev Dyn (2008) 1.29
Temporal relationship between primary and motile ciliogenesis in airway epithelial cells. Am J Respir Cell Mol Biol (2010) 1.28
Purinergic inhibition of ENaC produces aldosterone escape. J Am Soc Nephrol (2010) 1.19
Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases. Proc Natl Acad Sci U S A (2011) 1.18
Force-response considerations in ciliary mechanosensation. Biophys J (2007) 1.18
Regulation of transport in the connecting tubule and cortical collecting duct. Compr Physiol (2012) 1.16
Flow regulation of collecting duct endothelin-1 production. Am J Physiol Renal Physiol (2010) 1.15
Polycystins and renovascular mechanosensory transduction. Nat Rev Nephrol (2010) 1.13
Morphological and functional features of hepatic cyst epithelium in autosomal dominant polycystic kidney disease. Am J Pathol (2008) 1.12
Primary cilia-mediated mechanotransduction in human mesenchymal stem cells. Stem Cells (2012) 1.11
ATP and adenosine in the local regulation of water transport and homeostasis by the kidney. Am J Physiol Regul Integr Comp Physiol (2008) 1.09
A role for the inositol kinase Ipk1 in ciliary beating and length maintenance. Proc Natl Acad Sci U S A (2007) 1.06
OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome. Hum Mol Genet (2012) 1.06
The type 3 adenylyl cyclase is required for novel object learning and extinction of contextual memory: role of cAMP signaling in primary cilia. J Neurosci (2011) 1.05
Targeting of beta-arrestin2 to the centrosome and primary cilium: role in cell proliferation control. PLoS One (2008) 1.04
The transition zone: an essential functional compartment of cilia. Cilia (2012) 1.02
Ciliar functions in the nephron. Pflugers Arch (2009) 0.99
Ciliary dysfunction in polycystic kidney disease: an emerging model with polarizing potential. Front Biosci (2008) 0.97
The mechanics of the primary cilium: an intricate structure with complex function. J Biomech (2011) 0.97
Renal cystic diseases: diverse phenotypes converge on the cilium/centrosome complex. Pediatr Nephrol (2006) 0.97
Osteocyte primary cilium and its role in bone mechanotransduction. Ann N Y Acad Sci (2010) 0.95
Primary cilia: highly sophisticated biological sensors. Sensors (Basel) (2009) 0.95
The ciliary flow sensor and polycystic kidney disease. Nephrol Dial Transplant (2013) 0.93
Polycystic liver diseases. Dig Liver Dis (2010) 0.93
CEP proteins: the knights of centrosome dynasty. Protoplasma (2013) 0.92
Evolutionary origins of sensation in metazoans: functional evidence for a new sensory organ in sponges. BMC Evol Biol (2014) 0.92
Vascular biology of the biliary epithelium. J Gastroenterol Hepatol (2013) 0.91
The primary cilium in different tissues-lessons from patients and animal models. Pediatr Nephrol (2010) 0.91
Cartilage abnormalities associated with defects of chondrocytic primary cilia in Bardet-Biedl syndrome mutant mice. J Orthop Res (2009) 0.90
The primary cilium as a dual sensor of mechanochemical signals in chondrocytes. Cell Mol Life Sci (2012) 0.89
Epigenetics and autosomal dominant polycystic kidney disease. Biochim Biophys Acta (2010) 0.88
Fluid flow sensing and triggered nucleotide release in epithelia. J Physiol (2008) 0.87
An Integrative Review of Mechanotransduction in Endothelial, Epithelial (Renal) and Dendritic Cells (Osteocytes). Cell Mol Bioeng (2011) 0.87
The primary cilium calcium channels and their role in flow sensing. Pflugers Arch (2014) 0.86
Shear stress-induced volume decrease in C11-MDCK cells by BK-alpha/beta4. Am J Physiol Renal Physiol (2010) 0.86
Emerging role of primary cilia as mechanosensors in osteocytes. Bone (2012) 0.86
Reciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways. Autophagy (2015) 0.86
Localization of Golgi 58K protein (formiminotransferase cyclodeaminase) to the centrosome. Histochem Cell Biol (2006) 0.85
How insights from cardiovascular developmental biology have impacted the care of infants and children with congenital heart disease. Mech Dev (2012) 0.85
Nephrocystin and ciliary defects not only in the kidney? Pediatr Nephrol (2007) 0.84
Compensatory Role of Inositol 5-Phosphatase INPP5B to OCRL in Primary Cilia Formation in Oculocerebrorenal Syndrome of Lowe. PLoS One (2013) 0.84
Novel insights into TRPV4 function in the kidney. Pflugers Arch (2012) 0.83
The primary cilium as a novel extracellular sensor in bone. Front Endocrinol (Lausanne) (2012) 0.82
Effect of localization, length and orientation of chondrocytic primary cilium on murine growth plate organization. J Theor Biol (2011) 0.82
Cilia movement regulates expression of the Raf-1 kinase inhibitor protein. Am J Physiol Renal Physiol (2011) 0.81
Multiple gene mutations in patients with type 2 autoimmune pancreatitis and its clinical features. Cent Eur J Immunol (2014) 0.81
Zebrafish inositol polyphosphate kinases: new effectors of cilia and developmental signaling. Adv Enzyme Regul (2009) 0.81
Endogenous ATP release inhibits electrogenic Na⁺ absorption and stimulates Cl⁻ secretion in MDCK cells. Purinergic Signal (2007) 0.80
Deciphering physiological role of the mechanosensitive TRPV4 channel in the distal nephron. Am J Physiol Renal Physiol (2014) 0.80
From bone abnormalities to mineral metabolism dysregulation in autosomal dominant polycystic kidney disease. Pediatr Nephrol (2013) 0.80
Ciliopathy is differentially distributed in the brain of a Bardet-Biedl syndrome mouse model. PLoS One (2014) 0.78
Regulation of polycystin-1 ciliary trafficking by motifs at its C-terminus and polycystin-2 but not by cleavage at the GPS site. J Cell Sci (2015) 0.78
Shear stress blunts tubuloglomerular feedback partially mediated by primary cilia and nitric oxide at the macula densa. Am J Physiol Regul Integr Comp Physiol (2015) 0.77
The type 3 adenylyl cyclase is required for the survival and maturation of newly generated granule cells in the olfactory bulb. PLoS One (2015) 0.77
Epidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na+/H+ exchanger. Am J Physiol Cell Physiol (2014) 0.77
Understanding renal physiology leads to therapeutic advances in renal disease. Physiology (Bethesda) (2015) 0.77
Role of renal TRP channels in physiology and pathology. Semin Immunopathol (2015) 0.77
Fine tuning of RFX/DAF-19-regulated target gene expression through binding to multiple sites in Caenorhabditis elegans. Nucleic Acids Res (2011) 0.76
Unilateral nephrectomy elongates primary cilia in the remaining kidney via reactive oxygen species. Sci Rep (2016) 0.76
The Trypanosome Flagellar Pocket Collar and Its Ring Forming Protein-TbBILBO1. Cells (2016) 0.75
Changes in the oviducal epithelium during the estrous cycle in the marsupial Monodelphis domestica. J Anat (2007) 0.75
Biological and Chemical Removal of Primary Cilia Affects Mechanical Activation of Chondrogenesis Markers in Chondroprogenitors and Hypertrophic Chondrocytes. Int J Mol Sci (2016) 0.75
Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD. Hum Genomics (2016) 0.75
Role of the Primary Cilia on the Macula Densa and Thick Ascending Limbs in Regulation of Sodium Excretion and Hemodynamics. Hypertension (2017) 0.75
Routes and machinery of primary cilium biogenesis. Cell Mol Life Sci (2017) 0.75
The renal cell primary cilium functions as a flow sensor. Curr Opin Nephrol Hypertens (2003) 1.80
Reticulated lipid probe fluorescence reveals MDCK cell apical membrane topography. Biophys J (2002) 0.82
Specific lectins map the distribution of fibronectin and beta 1-integrin on living MDCK cells. Exp Cell Res (2002) 0.80
Focus on "Claudins create charge-selective channels in the paracellular pathway between epithelial cells". Am J Physiol Cell Physiol (2002) 0.78
Basic principles of microscope objectives. Biotechniques (2002) 0.76
Imaging at low light levels with cooled and intensified charge-coupled device cameras. Methods Enzymol (2003) 0.75