Published in Pflugers Arch on December 04, 2012
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PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4. J Biol Chem (2006) 1.71
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A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery. J Biol Chem (2006) 1.70
TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity. J Cell Biol (2005) 1.68
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Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site. J Biol Chem (2003) 1.60
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Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress. J Biol Chem (2003) 1.50
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Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2. Physiol Genomics (2001) 1.46
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Connexin 30 deficiency impairs renal tubular ATP release and pressure natriuresis. J Am Soc Nephrol (2009) 1.37
TRPV4 as a flow sensor in flow-dependent K+ secretion from the cortical collecting duct. Am J Physiol Renal Physiol (2006) 1.37
Differential activation of the volume-sensitive cation channel TRP12 (OTRPC4) and volume-regulated anion currents in HEK-293 cells. Pflugers Arch (2001) 1.36
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Activation of Trpv4 reduces the hyperproliferative phenotype of cystic cholangiocytes from an animal model of ARPKD. Gastroenterology (2010) 1.20
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Intrarenal purinergic signaling in the control of renal tubular transport. Annu Rev Physiol (2010) 1.15
Modulation of TRPV4 gating by intra- and extracellular Ca2+. Cell Calcium (2003) 1.15
Slow spontaneous [Ca2+] i oscillations reflect nucleotide release from renal epithelia. Pflugers Arch (2007) 1.14
Hypertonicity sensing in organum vasculosum lamina terminalis neurons: a mechanical process involving TRPV1 but not TRPV4. J Neurosci (2011) 1.10
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Tyrosine phosphorylation modulates the activity of TRPV4 in response to defined stimuli. J Biol Chem (2008) 1.04
Released nucleotides amplify the cilium-dependent, flow-induced [Ca2+]i response in MDCK cells. Acta Physiol (Oxf) (2009) 1.03
Potential role of purinergic signaling in urinary concentration in inner medulla: insights from P2Y2 receptor gene knockout mice. Am J Physiol Renal Physiol (2008) 1.03
Function of transient receptor potential cation channel subfamily V member 4 (TRPV4) as a mechanical transducer in flow-sensitive segments of renal collecting duct system. J Biol Chem (2012) 1.03
Marked attenuation of inflammatory mediator-induced C-fiber sensitization for mechanical and hypotonic stimuli in TRPV4-/- mice. Mol Pain (2007) 1.01
Atomic force microscopy reveals the alternating subunit arrangement of the TRPP2-TRPV4 heterotetramer. Biophys J (2010) 1.01
TRPV4 mediates hypotonicity-induced ATP release by the thick ascending limb. Am J Physiol Renal Physiol (2008) 1.00
The cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channel. J Biol Chem (2000) 1.00
Microtubule-associated [corrected] protein 7 increases the membrane expression of transient receptor potential vanilloid 4 (TRPV4). J Biol Chem (2003) 0.99
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Interdomain interactions control Ca2+-dependent potentiation in the cation channel TRPV4. PLoS One (2010) 0.98
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Developmental regulation of expression of renal potassium secretory channels. Curr Opin Nephrol Hypertens (2004) 0.96
Functional interaction of the cation channel transient receptor potential vanilloid 4 (TRPV4) and actin in volume regulation. Eur J Cell Biol (2008) 0.94
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Dual role of the TRPV4 channel as a sensor of flow and osmolality in renal epithelial cells. Am J Physiol Renal Physiol (2007) 1.50
Angiotensin II increases activity of the epithelial Na+ channel (ENaC) in distal nephron additively to aldosterone. J Biol Chem (2011) 1.47
Bax-mediated Ca2+ mobilization promotes cytochrome c release during apoptosis. J Biol Chem (2002) 1.35
A carboxy-terminal inter-helix linker as the site of phosphatidylinositol 4,5-bisphosphate action on Kv7 (M-type) K+ channels. J Gen Physiol (2008) 1.33
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Homomeric and heteromeric assembly of KCNQ (Kv7) K+ channels assayed by total internal reflection fluorescence/fluorescence resonance energy transfer and patch clamp analysis. J Biol Chem (2008) 1.16
Ca2+/calmodulin disrupts AKAP79/150 interactions with KCNQ (M-Type) K+ channels. J Neurosci (2010) 1.09
Tumor blood flow measured by PET dynamic imaging of first-pass 18F-FDG uptake: a comparison with 15O-labeled water-measured blood flow. J Nucl Med (2008) 1.08
Bradykinin acutely inhibits activity of the epithelial Na+ channel in mammalian aldosterone-sensitive distal nephron. Am J Physiol Renal Physiol (2011) 1.06
Calmodulin binding to M-type K+ channels assayed by TIRF/FRET in living cells. J Physiol (2008) 1.06
AKAP79/150 signal complexes in G-protein modulation of neuronal ion channels. J Neurosci (2011) 1.04
Function of transient receptor potential cation channel subfamily V member 4 (TRPV4) as a mechanical transducer in flow-sensitive segments of renal collecting duct system. J Biol Chem (2012) 1.03
Heteromeric TRPV4-C1 channels contribute to store-operated Ca(2+) entry in vascular endothelial cells. Cell Calcium (2011) 1.00
Af17 deficiency increases sodium excretion and decreases blood pressure. J Am Soc Nephrol (2011) 1.00
Determinants of TRPV4 activity following selective activation by small molecule agonist GSK1016790A. PLoS One (2011) 0.99
Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: characterization of interaction of NSAIDs with phosphatidylcholine. Biochim Biophys Acta (2012) 0.97
Purinergic activation of Ca2+-permeable TRPV4 channels is essential for mechano-sensitivity in the aldosterone-sensitive distal nephron. PLoS One (2011) 0.91
Direct inhibition of basolateral Kir4.1/5.1 and Kir4.1 channels in the cortical collecting duct by dopamine. Am J Physiol Renal Physiol (2013) 0.91
TRPV1 channels make major contributions to behavioral hypersensitivity and spontaneous activity in nociceptors after spinal cord injury. Pain (2013) 0.90
Salt-dependent inhibition of epithelial Na+ channel-mediated sodium reabsorption in the aldosterone-sensitive distal nephron by bradykinin. Hypertension (2012) 0.90
Hypotonicity-induced TRPV4 function in renal collecting duct cells: modulation by progressive cross-talk with Ca2+-activated K+ channels. Cell Calcium (2011) 0.90
Direct activation of ENaC by angiotensin II: recent advances and new insights. Curr Hypertens Rep (2013) 0.89
TRPC-mediated actin-myosin contraction is critical for BBB disruption following hypoxic stress. Am J Physiol Cell Physiol (2010) 0.88
Critical role of TRPP2 and TRPC1 channels in stretch-induced injury of blood-brain barrier endothelial cells. Brain Res (2011) 0.84
Primary aldosteronism and impaired natriuresis in mice underexpressing TGFβ1. Proc Natl Acad Sci U S A (2013) 0.83
Long-lasting hyperexcitability induced by depolarization in the absence of detectable Ca2+ signals. J Neurophysiol (2009) 0.82
Discrete control of TRPV4 channel function in the distal nephron by protein kinases A and C. J Biol Chem (2013) 0.82
Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens (2014) 0.80
Ca2+ Imaging as a tool to assess TRP channel function in murine distal nephrons. Methods Mol Biol (2013) 0.79
VASP: a TRPC4-associated phosphoprotein that mediates PKG-induced inhibition of store-operated calcium influx. Am J Physiol Renal Physiol (2007) 0.76
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Correction: Emerging Role of the Calcium-Activated, Small Conductance, SK3 K+ Channel in Distal Tubule Function: Regulation by TRPV4. PLoS One (2016) 0.75