Published in Eur J Pharmacol on March 07, 2005
Helping oxytocin deliver: considerations in the development of oxytocin-based therapeutics for brain disorders. Front Neurosci (2013) 1.16
Functional selective oxytocin-derived agonists discriminate between individual G protein family subtypes. J Biol Chem (2011) 0.98
Assessing the antidepressant-like effects of carbetocin, an oxytocin agonist, using a modification of the forced swimming test. Psychopharmacology (Berl) (2010) 0.86
Carbetocin is a Functional Selective Gq Agonist That Does Not Promote Oxytocin Receptor Recycling After Inducing β-Arrestin-Independent Internalisation. J Neuroendocrinol (2016) 0.77
The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion. Blood (2003) 3.51
A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model. J Clin Invest (2004) 2.52
Inhibitory effect of barusiban and atosiban on oxytocin-induced contractions of myometrium from preterm and term pregnant women. J Soc Gynecol Investig (2004) 1.63
Receptor for advanced glycation end products is subjected to protein ectodomain shedding by metalloproteinases. J Biol Chem (2008) 1.52
Genomic structure and functional characterization of the human ADAM10 promoter. FASEB J (2005) 1.31
Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin. FASEB J (2009) 1.28
Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs. EMBO J (2002) 1.22
The non-amyloidogenic pathway: structure and function of alpha-secretases. Subcell Biochem (2005) 1.11
Cholesterol as stabilizer of the oxytocin receptor. Biochim Biophys Acta (2002) 1.10
The disintegrin ADAM9 indirectly contributes to the physiological processing of cellular prion by modulating ADAM10 activity. J Biol Chem (2005) 1.09
ADAM-10 over-expression increases cortical synaptogenesis. Neurobiol Aging (2006) 1.08
The neuropeptide PACAP promotes the alpha-secretase pathway for processing the Alzheimer amyloid precursor protein. FASEB J (2006) 1.07
Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related gamma-secretase dysfunction. J Biol Chem (2009) 1.06
The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10. Cell Mol Life Sci (2012) 1.05
Tumor necrosis factor-alpha converting enzyme is processed by proprotein-convertases to its mature form which is degraded upon phorbol ester stimulation. Eur J Biochem (2003) 1.04
Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice. FASEB J (2011) 1.00
Shedding of the amyloid precursor protein-like protein APLP2 by disintegrin-metalloproteinases. FEBS J (2005) 1.00
Upregulation of the alpha-secretase ADAM10--risk or reason for hope? FEBS J (2010) 1.00
Ectodomain shedding of the receptor for advanced glycation end products: a novel therapeutic target for Alzheimer's disease. Cell Mol Life Sci (2009) 0.98
Expression of the anti-amyloidogenic secretase ADAM10 is suppressed by its 5'-untranslated region. J Biol Chem (2010) 0.94
Alpha-secretase activation--an approach to Alzheimer's disease therapy. Neurodegener Dis (2006) 0.93
Influence of ADAM10 on prion protein processing and scrapie infectiosity in vivo. Neurobiol Dis (2009) 0.92
Statins stimulate the production of a soluble form of the receptor for advanced glycation end products. J Lipid Res (2013) 0.91
Over-expression of two different forms of the alpha-secretase ADAM10 affects learning and memory in mice. Behav Brain Res (2006) 0.90
Unfolded protein response signaling by transcription factor XBP-1 regulates ADAM10 and is affected in Alzheimer's disease. FASEB J (2013) 0.90
The effects of alpha-secretase ADAM10 on the proteolysis of neuregulin-1. FEBS J (2009) 0.88
Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice. BMC Genomics (2009) 0.88
Increased acetylcholine levels in skin biopsies of patients with atopic dermatitis. Life Sci (2003) 0.88
Transport of plasma membrane-derived cholesterol and the function of Niemann-Pick C1 Protein. FASEB J (2003) 0.87
Gradient-echo and CRAZED imaging for minute detection of Alzheimer plaques in an APPV717I x ADAM10-dn mouse model. Magn Reson Med (2007) 0.87
Induction of RAGE shedding by activation of G protein-coupled receptors. PLoS One (2012) 0.87
Regulated proteolysis of RAGE and AbetaPP as possible link between type 2 diabetes mellitus and Alzheimer's disease. J Alzheimers Dis (2009) 0.86
Cholesterol and steroid hormones: modulators of oxytocin receptor function. Prog Brain Res (2002) 0.85
A cellular metalloproteinase activates Vibrio cholerae pro-cytolysin. J Biol Chem (2004) 0.85
Regulation of α-secretase ADAM10 expression and activity. Exp Brain Res (2011) 0.85
CSF APPs alpha and phosphorylated tau protein levels in mild cognitive impairment and dementia of Alzheimer's type. J Geriatr Psychiatry Neurol (2008) 0.84
The Role of the anti-amyloidogenic secretase ADAM10 in shedding the APP-like proteins. Curr Alzheimer Res (2012) 0.84
A closer look at the cholesterol sensor. Trends Biochem Sci (2002) 0.83
Effect of a dominant-negative form of ADAM10 in a mouse model of Alzheimer's disease. J Alzheimers Dis (2009) 0.82
FE 200 440: a selective oxytocin antagonist on the term-pregnant human uterus. BJOG (2003) 0.81
Melatonin stimulates the nonamyloidogenic processing of βAPP through the positive transcriptional regulation of ADAM10 and ADAM17. J Pineal Res (2014) 0.80
Statins and the squalene synthase inhibitor zaragozic acid stimulate the non-amyloidogenic pathway of amyloid-beta protein precursor processing by suppression of cholesterol synthesis. J Alzheimers Dis (2010) 0.80
Intestinal cholesterol absorption: identification of different binding proteins for cholesterol and cholesterol absorption inhibitors in the enterocyte brush border membrane. Biochim Biophys Acta (2003) 0.78
Acitretin, an enhancer of alpha-secretase expression, crosses the blood-brain barrier and is not eliminated by P-glycoprotein. Neurodegener Dis (2012) 0.76
Amphiphilic HPMA-LMA copolymers increase the transport of Rhodamine 123 across a BBB model without harming its barrier integrity. J Control Release (2012) 0.76
Synthesis of maleimide-functionalyzed HPMA-copolymers and in vitro characterization of the aRAGE- and human immunoglobulin (huIgG)-polymer conjugates. Macromol Biosci (2012) 0.75