Published in Int J Biochem Cell Biol on January 11, 2005
A reversible form of lysine acetylation in the ER and Golgi lumen controls the molecular stabilization of BACE1. Biochem J (2007) 1.40
Aging of the brain, neurotrophin signaling, and Alzheimer's disease: is IGF1-R the common culprit? Neurobiol Aging (2007) 1.16
DNA double-strand breaks: a potential causative factor for mammalian aging? Mech Ageing Dev (2008) 1.10
Antagonistic pleiotropy and p53. Mech Ageing Dev (2008) 0.97
p53 as an intervention target for cancer and aging. Pathobiol Aging Age Relat Dis (2013) 0.89
Δ40 Isoform of p53 controls β-cell proliferation and glucose homeostasis in mice. Diabetes (2011) 0.87
Running on empty: how p53 controls INS/IGF signaling and affects life span. Exp Gerontol (2008) 0.84
P44, the 'longevity-assurance' isoform of P53, regulates tau phosphorylation and is activated in an age-dependent fashion. Aging Cell (2014) 0.79
p53 binds the mdmx mRNA and controls its translation. Oncogene (2016) 0.78
p53 and aging: role of p66Shc. Aging (Albany NY) (2013) 0.77
The amyloid precursor protein (APP) intracellular domain regulates translation of p44, a short isoform of p53, through an IRES-dependent mechanism. Neurobiol Aging (2015) 0.76
Dual regulation of TERT activity through transcription and splicing by DeltaNP63alpha. Aging (Albany NY) (2008) 0.76
Δ40p53 is involved in the inactivation of autophagy and contributes to inhibition of cell death in HCT116-Δ40p53 cells. Oncotarget (2017) 0.75
The Δ133p53 Isoform Reduces Wtp53-induced Stimulation of DNA Pol γ Activity in the Presence and Absence of D4T. Aging Dis (2017) 0.75
The emerging role of alternative splicing in senescence and aging. Aging Cell (2017) 0.75
Phosphorylation regulates SIRT1 function. PLoS One (2008) 2.30
Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model. Diabetes (2012) 1.98
Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure. Mol Cell Biol (2009) 1.74
Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy. Mol Neurodegener (2012) 1.63
Progressive loss of SIRT1 with cell cycle withdrawal. Aging Cell (2006) 1.54
Methyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genes. Diabetes (2008) 1.46
Isolation and proteomic analysis of mouse sperm detergent-resistant membrane fractions: evidence for dissociation of lipid rafts during capacitation. Biol Reprod (2005) 1.38
Chronic mild reduction of cerebral perfusion pressure induces ischemic tolerance in focal cerebral ischemia. Stroke (2005) 1.31
Prognostic value of subacute crossed cerebellar diaschisis: single-photon emission CT study in patients with middle cerebral artery territory infarct. AJNR Am J Neuroradiol (2002) 1.26
Regulation of pancreatic juxtaductal endocrine cell formation by FoxO1. Mol Cell Biol (2009) 1.24
Granulocyte colony-stimulating factor enhances arteriogenesis and ameliorates cerebral damage in a mouse model of ischemic stroke. Stroke (2011) 1.11
Granulocyte-macrophage colony-stimulating factor enhances leptomeningeal collateral growth induced by common carotid artery occlusion. Stroke (2008) 1.07
Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes. J Biol Chem (2010) 1.06
Involvement of ICAM-1 in the progression of atherosclerosis in APOE-knockout mice. Atherosclerosis (2002) 1.04
Downregulation of SIK2 expression promotes the melanogenic program in mice. Pigment Cell Melanoma Res (2010) 1.02
Increased proliferation of neural progenitor cells but reduced survival of newborn cells in the contralateral hippocampus after focal cerebral ischemia in rats. J Cereb Blood Flow Metab (2002) 1.02
Ectopic osteogenesis using adenoviral bone morphogenetic protein (BMP)-4 and BMP-6 gene transfer. Mol Ther (2002) 0.99
Involvement of SIK3 in glucose and lipid homeostasis in mice. PLoS One (2012) 0.99
Mouse SLLP1, a sperm lysozyme-like protein involved in sperm-egg binding and fertilization. Dev Biol (2005) 0.99
FoxO1 as a double-edged sword in the pancreas: analysis of pancreas- and β-cell-specific FoxO1 knockout mice. Am J Physiol Endocrinol Metab (2012) 0.98
A novel regulatory function of sweet taste-sensing receptor in adipogenic differentiation of 3T3-L1 cells. PLoS One (2013) 0.96
Cilostazol, not aspirin, reduces ischemic brain injury via endothelial protection in spontaneously hypertensive rats. Stroke (2011) 0.96
An angiotensin II type 1 receptor blocker can preserve endothelial function and attenuate brain ischemic damage in spontaneously hypertensive rats. J Neurosci Res (2010) 0.93
Overexpression of FoxO1 in the hypothalamus and pancreas causes obesity and glucose intolerance. Endocrinology (2011) 0.92
Membrane association of estrogen receptor alpha mediates estrogen effect on MAPK activation. Biochem Biophys Res Commun (2002) 0.92
Translational control of inducible nitric oxide synthase by p38 MAPK in islet β-cells. Mol Endocrinol (2012) 0.92
Activation of NR2A receptors induces ischemic tolerance through CREB signaling. J Cereb Blood Flow Metab (2010) 0.90
Expression and function of Set7/9 in pancreatic islets. Islets (2010) 0.90
Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling. Cell Cycle (2011) 0.89
A potent inhibitor of SIK2, 3, 3', 7-trihydroxy-4'-methoxyflavon (4'-O-methylfisetin), promotes melanogenesis in B16F10 melanoma cells. PLoS One (2011) 0.88
Rho-kinase activation in endothelial cells contributes to expansion of infarction after focal cerebral ischemia. J Neurosci Res (2007) 0.88
Hypertension impairs leptomeningeal collateral growth after common carotid artery occlusion: restoration by antihypertensive treatment. J Neurosci Res (2011) 0.88
Facial solar UV exposure of Austrian farmers during occupation. Photochem Photobiol (2010) 0.88
Δ40 Isoform of p53 controls β-cell proliferation and glucose homeostasis in mice. Diabetes (2011) 0.87
Identification of the deleted in liver cancer 1 gene, DLC1, as a candidate meningioma tumor suppressor. Neurosurgery (2008) 0.87
Differential expression of Musashi1 and nestin in the adult rat hippocampus after ischemia. J Neurosci Res (2002) 0.87
Genetic defect in phospholipase Cδ1 protects mice from obesity by regulating thermogenesis and adipogenesis. Diabetes (2011) 0.86
FoxO1 gain of function in the pancreas causes glucose intolerance, polycystic pancreas, and islet hypervascularization. PLoS One (2012) 0.86
Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation. PLoS One (2012) 0.86
Protective effect of apolipoprotein E against ischemic neuronal injury is mediated through antioxidant action. J Neurosci Res (2002) 0.85
CRE-mediated gene transcription in the peri-infarct area after focal cerebral ischemia in mice. J Neurosci Res (2004) 0.84
A critical role of fatty acid binding protein 4 and 5 (FABP4/5) in the systemic response to fasting. PLoS One (2013) 0.83
Postischemic administration of HMG CoA reductase inhibitor inhibits infarct expansion after transient middle cerebral artery occlusion. Brain Res (2007) 0.82
Postischemic administration of angiotensin II type 1 receptor blocker reduces cerebral infarction size in hypertensive rats. Hypertens Res (2009) 0.81
Long-term effects of an Apocynum venetum extract on brain monoamine levels and beta-AR density in rats. Pharmacol Biochem Behav (2003) 0.80
Necdin controls Foxo1 acetylation in hypothalamic arcuate neurons to modulate the thyroid axis. J Neurosci (2012) 0.80
Characterization of a novel polyclonal anti-hypusine antibody. Springerplus (2013) 0.80
Postischemic exercise decreases neurogenesis in the adult rat dentate gyrus. Neurosci Lett (2006) 0.78
Functional deterioration of endothelial nitric oxide synthase after focal cerebral ischemia. J Cereb Blood Flow Metab (2013) 0.78
UV exposition during typical lifestyle behavior in an urban environment. Photochem Photobiol (2010) 0.78
Protection against high-fat diet-induced obesity in Helz2-deficient male mice due to enhanced expression of hepatic leptin receptor. Endocrinology (2014) 0.78
Sirt1 rescues the obesity induced by insulin-resistant constitutively-nuclear FoxO1 in POMC neurons of male mice. Obesity (Silver Spring) (2014) 0.77
Protective effects of polyamine depletion in mouse models of type 1 diabetes: implications for therapy. Amino Acids (2013) 0.77
Infiltrating macrophages as in vivo targets for intravenous gene delivery in cerebral infarction. Stroke (2004) 0.77
Maintenance of Pdx1 mRNA translation in islet β-cells during the unfolded protein response. Mol Endocrinol (2014) 0.77
Differential Akt phosphorylation at Ser473 and Thr308 in cultured neurons after exposure to glutamate in rats. Neurosci Lett (2002) 0.77
Deoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetes. J Biol Chem (2013) 0.76
Double Seronegative Myasthenia Gravis with Anti-LRP4 Antibodies Presenting with Dropped Head and Acute Respiratory Insufficiency. Intern Med (2016) 0.75
[Differences between Graduate School Systems between Japan and the United States]. Seishin Shinkeigaku Zasshi (2015) 0.75
Management of the Nipple-Areola Complex in Selected Patients Undergoing Primary Breast Reconstruction: A Comparison of Immediate Replantation and Delayed Reconstruction. Ann Plast Surg (2017) 0.75
Potential Application of 5-Aryl-Substituted 2-Amino- benzamide Type of HDAC1/2-Selective Inhibitors to Pharmaceuticals. Curr Pharm Des (2016) 0.75
[CREB activation is a key player for ischemic tolerance in the brain]. Rinsho Shinkeigaku (2012) 0.75
ATF3 expression is induced by low glucose in pancreatic α and β cells and regulates glucagon but not insulin gene transcription. Endocr J (2013) 0.75