Daniel J Dumont

Author PubWeight™ 52.14‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of antiangiogenesis. Cancer Cell 2005 3.74
2 A role for survivin in chemoresistance of endothelial cells mediated by VEGF. Proc Natl Acad Sci U S A 2002 2.16
3 Vascular endothelial growth factor-mediated decrease in plasma soluble vascular endothelial growth factor receptor-2 levels as a surrogate biomarker for tumor growth. Cancer Res 2008 1.78
4 Angiopoietin-2 promotes myeloid cell infiltration in a β₂-integrin-dependent manner. Blood 2011 1.73
5 Inhibition of Tie-2 signaling induces endothelial cell apoptosis, decreases Akt signaling, and induces endothelial cell expression of the endogenous anti-angiogenic molecule, thrombospondin-1. Cancer Biol Ther 2004 1.62
6 Angiogenic actions of angiopoietin-1 require endothelium-derived nitric oxide. Am J Pathol 2003 1.48
7 Problems with co-funding in Canada. Science 2005 1.48
8 Transgenic induction of vascular endothelial growth factor-C is strongly angiogenic in mouse embryos but leads to persistent lymphatic hyperplasia in adult tissues. Am J Pathol 2008 1.38
9 Cell-based angiopoietin-1 gene therapy for acute lung injury. Am J Respir Crit Care Med 2007 1.33
10 The angiopoietins and Tie2/Tek: adding to the complexity of cardiovascular development. Semin Cell Dev Biol 2002 1.31
11 Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited. Acta Neuropathol 2012 1.30
12 Angiopoietin-2 impairs revascularization after limb ischemia. Circ Res 2007 1.29
13 The synthetic tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis. Crit Care 2011 1.25
14 Activation of Tie2 by angiopoietin-1 and angiopoietin-2 results in their release and receptor internalization. J Cell Sci 2006 1.17
15 The inositol phosphatase SHIP-1 is negatively regulated by Fli-1 and its loss accelerates leukemogenesis. Blood 2010 1.12
16 Hepatocyte growth factor mediates angiopoietin-induced smooth muscle cell recruitment. Blood 2006 1.11
17 A cyclosporine-sensitive psoriasis-like disease produced in Tie2 transgenic mice. Am J Pathol 2005 1.04
18 Nonlinear multicontrast microscopy of hematoxylin-and-eosin-stained histological sections. J Biomed Opt 2010 1.04
19 Dok-R mediates attenuation of epidermal growth factor-dependent mitogen-activated protein kinase and Akt activation through processive recruitment of c-Src and Csk. Mol Cell Biol 2005 1.02
20 Vascular-specific growth factor angiopoietin 1 is involved in the organization of neuronal processes. J Comp Neurol 2005 1.01
21 Enhanced expression of VEGF-A in β cells increases endothelial cell number but impairs islet morphogenesis and β cell proliferation. Dev Biol 2012 1.01
22 A unique autophosphorylation site on Tie2/Tek mediates Dok-R phosphotyrosine binding domain binding and function. Mol Cell Biol 2003 1.00
23 The angiopietin-1-Tie2 pathway prevents rather than promotes pulmonary arterial hypertension in transgenic mice. J Exp Med 2009 0.98
24 Focused ultrasound-mediated bbb disruption is associated with an increase in activation of AKT: experimental study in rats. BMC Neurol 2010 0.97
25 Heterogeneity of Tie2 expression in tumor microcirculation: influence of cancer type, implantation site, and response to therapy. Am J Pathol 2005 0.97
26 Differential response of lymphatic, venous and arterial endothelial cells to angiopoietin-1 and angiopoietin-2. BMC Cell Biol 2007 0.96
27 Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling. Proc Natl Acad Sci U S A 2012 0.95
28 Functional inhibition of secreted angiopoietin: a novel role for angiopoietin 1 in coronary vessel patterning. Biochem Biophys Res Commun 2004 0.94
29 Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature. BMC Dev Biol 2010 0.90
30 Angiopoietin-1 causes reversible degradation of the portal microcirculation in mice: implications for treatment of liver disease. Am J Pathol 2004 0.90
31 Selective role of a distinct tyrosine residue on Tie2 in heart development and early hematopoiesis. Mol Cell Biol 2005 0.86
32 Angiopoietin 1 expression levels in the myocardium direct coronary vessel development. Dev Dyn 2004 0.86
33 Tie2-dependent neovascularization of the ischemic hindlimb is mediated by angiopoietin-2. PLoS One 2012 0.85
34 Dok-R binds c-Abl and regulates Abl kinase activity and mediates cytoskeletal reorganization. J Biol Chem 2003 0.85
35 Vasculotide, an Angiopoietin-1 mimetic, reduces acute skin ionizing radiation damage in a preclinical mouse model. BMC Cancer 2014 0.84
36 Transgenic expression of Angiopoietin 1 in the liver leads to changes in lymphatic and blood vessel architecture. Biochem Biophys Res Commun 2006 0.80
37 Differential proteomic analysis of lymphatic, venous, and arterial endothelial cells extracted from bovine mesenteric vessels. Proteomics 2010 0.80
38 Oligomerized Tie2 localizes to clathrin-coated pits in response to angiopoietin-1. Histochem Cell Biol 2009 0.80
39 Cell-cell interactions influence vascular reprogramming by Prox1 during embryonic development. PLoS One 2013 0.79
40 An eosinophil immune response characterizes the inflammatory skin disease observed in Tie-2 transgenic mice. J Leukoc Biol 2008 0.79
41 Angiopoietin-1-induced ubiquitylation of Tie2 by c-Cbl is required for internalization and degradation. Biochem J 2009 0.78
42 Gene expression analysis of Tek/Tie2 signaling. Physiol Genomics 2005 0.78
43 Loss of Tie2 receptor compromises embryonic stem cell-derived endothelial but not hematopoietic cell survival. Blood 2005 0.77
44 Lymphangiogenesis following obstruction of large postnodal lymphatics in sheep. Microvasc Res 2006 0.77
45 Inhibition of T cell protein tyrosine phosphatase enhances interleukin-18-dependent hematopoietic stem cell expansion. Stem Cells 2013 0.76
46 Tyrosine phosphorylation of Grb14 by Tie2. Cell Commun Signal 2010 0.75