Published in Development on March 02, 2005
Close sequence comparisons are sufficient to identify human cis-regulatory elements. Genome Res (2006) 3.92
Conservation of core gene expression in vertebrate tissues. J Biol (2009) 2.84
Two or four bristles: functional evolution of an enhancer of scute in Drosophilidae. PLoS Biol (2006) 2.23
Evolution of gene regulatory networks controlling body plan development. Cell (2011) 1.80
On the relation between promoter divergence and gene expression evolution. Mol Syst Biol (2008) 1.43
A multicassette Gateway vector set for high throughput and comparative analyses in ciona and vertebrate embryos. PLoS One (2007) 1.36
Shuffling of cis-regulatory elements is a pervasive feature of the vertebrate lineage. Genome Biol (2006) 1.16
Transphyletic conservation of developmental regulatory state in animal evolution. Proc Natl Acad Sci U S A (2011) 1.09
Detection of weakly conserved ancestral mammalian regulatory sequences by primate comparisons. Genome Biol (2007) 1.08
Evolutionary constraint on Otx2 neuroectoderm enhancers-deep conservation from skate to mouse and unique divergence in teleost. Proc Natl Acad Sci U S A (2006) 1.06
Conserved non-coding elements and cis regulation: actions speak louder than words. Development (2013) 1.00
Comprehensive characterization of the cis-regulatory code responsible for the spatio-temporal expression of olSix3.2 in the developing medaka forebrain. Genome Biol (2007) 0.95
An evolutionary constraint: strongly disfavored class of change in DNA sequence during divergence of cis-regulatory modules. Proc Natl Acad Sci U S A (2005) 0.95
Highly conserved elements discovered in vertebrates are present in non-syntenic loci of tunicates, act as enhancers and can be transcribed during development. Nucleic Acids Res (2013) 0.94
Coevolution within and between regulatory loci can preserve promoter function despite evolutionary rate acceleration. PLoS Genet (2012) 0.92
Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes. Proc Natl Acad Sci U S A (2007) 0.92
A comprehensive analysis of gene expression evolution between humans and mice. Evol Bioinform Online (2009) 0.92
Genetic and genomic toolbox of the chordate Ciona intestinalis. Genetics (2012) 0.91
Evolutionary meandering of intermolecular interactions along the drift barrier. Proc Natl Acad Sci U S A (2014) 0.89
Divergent mechanisms regulate conserved cardiopharyngeal development and gene expression in distantly related ascidians. Elife (2014) 0.88
Cis-regulatory organization of the Pax6 gene in the ascidian Ciona intestinalis. Dev Biol (2008) 0.87
Postmitotic diversification of olfactory neuron types is mediated by differential activities of the HMG-box transcription factor SOX-2. EMBO J (2015) 0.87
Pervasive divergence of transcriptional gene regulation in Caenorhabditis nematodes. PLoS Genet (2014) 0.85
Dynamic in vivo binding of transcription factors to cis-regulatory modules of cer and gsc in the stepwise formation of the Spemann-Mangold organizer. Development (2012) 0.84
Lineage analysis of micromere 4d, a super-phylotypic cell for Lophotrochozoa, in the leech Helobdella and the sludgeworm Tubifex. Dev Biol (2011) 0.84
Multiple signaling pathways coordinate to induce a threshold response in a chordate embryo. PLoS Genet (2013) 0.83
An otx/nodal regulatory signature for posterior neural development in ascidians. PLoS Genet (2014) 0.77
Phylum-Level Conservation of Regulatory Information in Nematodes despite Extensive Non-coding Sequence Divergence. PLoS Genet (2015) 0.77
Tunicates: exploring the sea shores and roaming the open ocean. A tribute to Thomas Huxley. Open Biol (2015) 0.75
Cis-regulatory timers for developmental gene expression. PLoS Biol (2013) 0.75
Uncoupling evolutionary changes in DNA sequence, transcription factor occupancy and enhancer activity. Elife (2017) 0.75
The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins. Science (2002) 11.11
DNA-binding specificities of human transcription factors. Cell (2013) 5.14
Experience-dependent transfer of Otx2 homeoprotein into the visual cortex activates postnatal plasticity. Cell (2008) 3.32
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development. Nat Neurosci (2003) 3.08
The amphioxus genome illuminates vertebrate origins and cephalochordate biology. Genome Res (2008) 3.04
Neural tissue in ascidian embryos is induced by FGF9/16/20, acting via a combination of maternal GATA and Ets transcription factors. Cell (2003) 2.37
Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition. Development (2004) 2.01
A cis-regulatory signature in ascidians and flies, independent of transcription factor binding sites. Curr Biol (2010) 1.93
Characterization of the pufferfish Otx2 cis-regulators reveals evolutionarily conserved genetic mechanisms for vertebrate head specification. Development (2003) 1.90
Analysis of multiple ethyl methanesulfonate-mutagenized Caenorhabditis elegans strains by whole-genome sequencing. Genetics (2010) 1.76
Improved genome assembly and evidence-based global gene model set for the chordate Ciona intestinalis: new insight into intron and operon populations. Genome Biol (2008) 1.75
Formation of the ascidian epidermal sensory neurons: insights into the origin of the chordate peripheral nervous system. PLoS Biol (2006) 1.65
Possible involvement of SINEs in mammalian-specific brain formation. Proc Natl Acad Sci U S A (2008) 1.54
Sequential activation of apical and basolateral contractility drives ascidian endoderm invagination. Curr Biol (2010) 1.53
Ciona intestinalis Hox gene cluster: Its dispersed structure and residual colinear expression in development. Proc Natl Acad Sci U S A (2004) 1.49
Functional roles of Otx2 transcription factor in postnatal mouse retinal development. Mol Cell Biol (2007) 1.46
Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm. Dev Cell (2005) 1.43
The ANISEED database: digital representation, formalization, and elucidation of a chordate developmental program. Genome Res (2010) 1.43
A quantitative approach to the study of cell shapes and interactions during early chordate embryogenesis. Curr Biol (2006) 1.40
A multicassette Gateway vector set for high throughput and comparative analyses in ciona and vertebrate embryos. PLoS One (2007) 1.36
Dosage-dependent hedgehog signals integrated with Wnt/beta-catenin signaling regulate external genitalia formation as an appendicular program. Development (2009) 1.31
A combinatorial code of maternal GATA, Ets and beta-catenin-TCF transcription factors specifies and patterns the early ascidian ectoderm. Development (2007) 1.22
Regulation of Otx2 expression and its functions in mouse forebrain and midbrain. Development (2004) 1.17
Ciona intestinalis cDNA projects: expressed sequence tag analyses and gene expression profiles during embryogenesis. Gene (2002) 1.14
Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm. Development (2004) 1.13
A genomewide survey of developmentally relevant genes in Ciona intestinalis. II. Genes for homeobox transcription factors. Dev Genes Evol (2003) 1.11
External mechanical cues trigger the establishment of the anterior-posterior axis in early mouse embryos. Dev Cell (2013) 1.10
Dkk3-Cre BAC transgenic mouse line: a tool for highly efficient gene deletion in retinal progenitor cells. Genesis (2007) 1.08
The neurobiology of the ascidian tadpole larva: recent developments in an ancient chordate. Annu Rev Neurosci (2004) 1.07
Comprehensive survey and classification of homeobox genes in the genome of amphioxus, Branchiostoma floridae. Dev Genes Evol (2008) 1.05
Cellular morphogenesis in ascidians: how to shape a simple tadpole. Curr Opin Genet Dev (2006) 1.05
Cell surface heparan sulfate chains regulate local reception of FGF signaling in the mouse embryo. Dev Cell (2011) 1.03
Genetic modifiers of otocephalic phenotypes in Otx2 heterozygous mutant mice. Development (2002) 1.02
Otx2 is required to respond to signals from anterior neural ridge for forebrain specification. Dev Biol (2002) 1.01
A conserved role for the MEK signalling pathway in neural tissue specification and posteriorisation in the invertebrate chordate, the ascidian Ciona intestinalis. Development (2003) 0.97
Deletion of Otx2 in GnRH neurons results in a mouse model of hypogonadotropic hypogonadism. Mol Endocrinol (2011) 0.97
Limited functions of Hox genes in the larval development of the ascidian Ciona intestinalis. Development (2010) 0.97
FGF signaling directs a center-to-pole expansion of tubulogenesis in mouse testis differentiation. Development (2010) 0.96
HrzicN, a new Zic family gene of ascidians, plays essential roles in the neural tube and notochord development. Development (2002) 0.96
Evolution of Brachyury proteins: identification of a novel regulatory domain conserved within Bilateria. Dev Biol (2003) 0.95
Highly conserved elements discovered in vertebrates are present in non-syntenic loci of tunicates, act as enhancers and can be transcribed during development. Nucleic Acids Res (2013) 0.94
HrNodal, the ascidian nodal-related gene, is expressed in the left side of the epidermis, and lies upstream of HrPitx. Dev Genes Evol (2002) 0.92
Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes. Proc Natl Acad Sci U S A (2007) 0.92
Guidelines for the nomenclature of genetic elements in tunicate genomes. Genesis (2014) 0.92
Aging of sensorimotor processes: a systematic study in Fitts' task. Exp Brain Res (2013) 0.91
Organization of Hox genes in ascidians: present, past, and future. Dev Dyn (2005) 0.91
Age-related differences in arithmetic problem-verification strategies. J Gerontol B Psychol Sci Soc Sci (2004) 0.91
Segregation of germ layer fates by nuclear migration-dependent localization of Not mRNA. Dev Cell (2010) 0.90
Divergent functions of two ancient Hydra Brachyury paralogues suggest specific roles for their C-terminal domains in tissue fate induction. Development (2007) 0.90
Antagonizing retinoic acid and FGF/MAPK pathways control posterior body patterning in the invertebrate chordate Ciona intestinalis. PLoS One (2012) 0.89
Dynamic change in the expression of developmental genes in the ascidian central nervous system: revisit to the tripartite model and the origin of the midbrain-hindbrain boundary region. Dev Biol (2007) 0.89
Highly divergent gene expression programs can lead to similar chordate larval body plans. Curr Biol (2009) 0.89
Fluorescent in situ hybridization to ascidian chromosomes. Zoolog Sci (2004) 0.88
Different brain mechanisms mediate two strategies in arithmetic: evidence from Event-Related brain Potentials. Neuropsychologia (2003) 0.88
Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells. Development (2012) 0.88
Ci-FoxA-a is the earliest zygotic determinant of the ascidian anterior ectoderm and directly activates Ci-sFRP1/5. Development (2006) 0.88
Identification of an intact ParaHox cluster with temporal colinearity but altered spatial colinearity in the hemichordate Ptychodera flava. BMC Evol Biol (2013) 0.88
Crème de la Kremen of Wnt signalling inhibition. Nat Cell Biol (2002) 0.88
Wnt asymmetry and the terminal division of neuronal progenitors. Cell Cycle (2009) 0.86
Attentional modulation of masked repetition and categorical priming in young and older adults. Cognition (2006) 0.86
Arithmetic split effects reflect strategy selection: an adult age comparative study in addition comparison and verification tasks. Can J Exp Psychol (2005) 0.86
Origin of mannose-binding lectin-associated serine protease (MASP)-1 and MASP-3 involved in the lectin complement pathway traced back to the invertebrate, amphioxus. J Immunol (2003) 0.85
A saturation screen for cis-acting regulatory DNA in the Hox genes of Ciona intestinalis. Proc Natl Acad Sci U S A (2005) 0.85
Expression of Bblhx3, a LIM-homeobox gene, in the development of amphioxus Branchiostoma belcheri tsingtauense. Mech Dev (2002) 0.85
The influence of cognitive reserve on strategy selection in normal aging. J Int Neuropsychol Soc (2013) 0.84
Identical genomic organization of two hemichordate hox clusters. Curr Biol (2012) 0.84
Evolutionary origins of blastoporal expression and organizer activity of the vertebrate gastrula organizer gene lhx1 and its ancient metazoan paralog lhx3. Development (2009) 0.84
Brd2 is required for cell cycle exit and neuronal differentiation through the E2F1 pathway in mouse neuroepithelial cells. Biochem Biophys Res Commun (2012) 0.84
Combining movement kinematics, efficiency functions, and Brinley plots to study age-related slowing of sensorimotor processes: insights from Fitts' task. Gerontology (2011) 0.83
Amphi-Eomes/Tbr1: an amphioxus cognate of vertebrate Eomesodermin and T-Brain1 genes whose expression reveals evolutionarily distinct domain in amphioxus development. J Exp Zool (2002) 0.82
Control of gastrula cell motility by the Goosecoid/Mix.1/ Siamois network: basic patterns and paradoxical effects. Dev Dyn (2008) 0.82
Formation of the digestive tract in Ciona intestinalis includes two distinct morphogenic processes between its anterior and posterior parts. Dev Dyn (2013) 0.82
Working memory, strategy execution, and strategy selection in mental arithmetic. Q J Exp Psychol (Hove) (2007) 0.80
Older and younger adults' strategies in approximate quantification. Acta Psychol (Amst) (2008) 0.80
Effects of aging on arithmetic problem-solving: an event-related brain potential study. J Cogn Neurosci (2005) 0.80
Comparison of the grade evaluated by "Liver damage" of Liver Cancer Study Group of Japan and Child-Pugh classification in patients with hepatocellular carcinoma. Hepatol Res (2006) 0.80
Maternal macho-1 is an intrinsic factor that makes cell response to the same FGF signal differ between mesenchyme and notochord induction in ascidian embryos. Development (2003) 0.80
Ascidian otx gene Hroth activates transcription of the brain-specific gene HrTRP. Dev Dyn (2002) 0.79
Within-item strategy switching: an age comparative study in adults. Psychol Aging (2012) 0.79
Roles of Hroth, the ascidian otx gene, in the differentiation of the brain (sensory vesicle) and anterior trunk epidermis in the larval development of Halocynthia roretzi. Mech Dev (2004) 0.79
Neural correlates of approximate quantification strategies in young and older adults: an fMRI study. Brain Res (2008) 0.79
Eye movement correlates of younger and older adults' strategies for complex addition. Acta Psychol (Amst) (2006) 0.79
Sequential difficulty effects during strategy execution. Exp Psychol (2012) 0.79
Ambulacrarian prototypical Hox and ParaHox gene complements of the indirect-developing hemichordate Balanoglossus simodensis. Dev Genes Evol (2009) 0.79
Strategic aspects of young, healthy older adults', and Alzheimer patients' arithmetic performance. Cortex (2007) 0.79
Spatial and temporal expression of two transcriptional isoforms of Lhx3, a LIM class homeobox gene, during embryogenesis of two phylogenetically remote ascidians, Halocynthia roretzi and Ciona intestinalis. Gene Expr Patterns (2010) 0.79
Repression of Rx gene on the left side of the sensory vesicle by Nodal signaling is crucial for right-sided formation of the ocellus photoreceptor in the development of Ciona intestinalis. Dev Biol (2011) 0.79
Clinical significance of positive immunoblotting but negative immunofluorescence for antimitochondrial antibodies in patients with liver diseases other than primary biliary cirrhosis. Autoimmunity (2002) 0.78
Approximate quantification in young, healthy older adults', and Alzheimer patients. Brain Cogn (2009) 0.78
Time-lapse imaging of live Phallusia embryos for creating 3D digital replicas. Cold Spring Harb Protoc (2011) 0.78
Automated enzymatic mitochondrial antibody assay for the diagnosis of primary biliary cirrhosis: applications of a routine diagnostic tool for the detection of antimitochondrial antibodies. J Gastroenterol Hepatol (2002) 0.78
Cytoplasmic intermediate filament protein expression in tunicate development: a specific marker for the test cells. Eur J Cell Biol (2002) 0.77
Online grammaticality judgments in French young and older adults. Exp Aging Res (2012) 0.77
Alzheimer's disease disrupts arithmetic fact retrieval processes but not arithmetic strategy selection. Brain Cogn (2003) 0.77
Evolution of CUT class homeobox genes: insights from the genome of the amphioxus, Branchiostoma floridae. Int J Dev Biol (2008) 0.77
Similar regulatory logic in Ciona intestinalis for two Wnt pathway modulators, ROR and SFRP-1/5. Dev Biol (2009) 0.77
Left-right asymmetric expression of Pitx is regulated by the asymmetric Nodal signaling through an intronic enhancer in Ciona intestinalis. Dev Genes Evol (2008) 0.77